LOCUS       BGC0001049             19177 bp    DNA     linear   PLN 14-JUL-2016
DEFINITION  Beauveria bassiana tenellin biosynthesis gene cluster.
ACCESSION   BGC0001049
VERSION     BGC0001049
KEYWORDS    .
SOURCE      Beauveria bassiana
  ORGANISM  Beauveria bassiana
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Cordycipitaceae;
            Beauveria.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:45:43
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 19177
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             join(1..585,650..1175,1238..1653)
                     /codon_start=1
                     /db_xref="GOA:A0JJT8"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002974"
                     /db_xref="UniProtKB/TrEMBL:A0JJT8"
                     /gene="tens1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 240.3; E-value: 6.7e-73)"
                     /gene_kind="biosynthetic-additional"
                     /product="hypothetical protein"
                     /protein_id="CAL69594.1"
                     /sec_met_domain="p450 (E-value: 2.1e-49, bitscore: 156.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPLLDSVSLPYLILSACLSVILLRRFLAHDKGGSKSIAQGCLPE
                     PRLRQWDPIFGFGIVISQARALRGHRYLEWLRDLHASMPHTKTFSANYGGYRWIFSIEP
                     EILKAVYATNLQNFGVEPIRQHPPGFQPFAHKGVSTSDGDDWSFSRTLIKPFFERSVYI
                     STDRIKPFADKFMTLLPDDGETFDIQPLLQRWFLDITSEFIFGKSQDSMTHADRAEVTW
                     AMADVLRGGRQRAQTHRILWAFNWDWWFEAVEKVHGFLNPYIRSTLKELEERQQRIKDG
                     LPVDEERTDLLWSMATMLPDEEELRSQVCLIFVPNNDTTSMFIGHCLYFLARNSNAWKR
                     LRDEVDAVGDAPITFEMLRNMKYLNGILNETHRLIPNNVTQVRAALSDVVLPLGGGPNG
                     KAPLDVRKGDIVSVTKTVMYRDPEQWGPDANEYRPERWDGMRGGWHFLPYGGGPRRCPA
                     QMMVQNESAYMLFRLAQKYSTIVARDPEPFRARMRIGPSSMHGVKIAFYK"
     protocluster    1..19177
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[6224:19176]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6225..19176
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     protocluster    1..19177
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[6224:19176]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      6225..19176
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..19177
                     /SMILES="C([*])C(-O)(C)NC(Cc1ccc(O)cc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="chemical_hybrid"
                     /product="T1PKS"
                     /product="NRPS"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..19177
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001049"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..19177
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     intron          586..649
                     /gene="tens"
                     /number=1
     exon            650..1175
                     /gene="tens"
                     /number=2
     intron          1176..1237
                     /gene="tens"
                     /number=2
     exon            1238..3443
                     /gene="tens"
                     /number=3
     gene            complement(order(1238..3443,3501..7498))
                     /gene="tens2"
     mRNA            complement(join(1238..3443,3501..7498))
                     /gene="tens2"
     CDS             complement(join(2061..3443,3501..3737))
                     /codon_start=1
                     /db_xref="GOA:A0JJT9"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002403"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="UniProtKB/TrEMBL:A0JJT9"
                     /gene="tens2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 98.1; E-value: 9.5e-30)"
                     /gene_kind="biosynthetic-additional"
                     /product="hypothetical protein"
                     /protein_id="CAL69595.1"
                     /sec_met_domain="p450 (E-value: 3.8e-30, bitscore: 93.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALFQAMSMVAQLGYYEKVAGVLGFLSIALLFWKLNHKPFYPALP
                     LAGEPPQRRWFSLSNRLRYYNDCAALFDEAYHTAYAKKGKAVLVPSMGVHTAMIMPESA
                     MNWAMSQPDDSLSIKKAFSELNQTKYSLGHGRYWEDPWQLDLVKAHLSSILQNLIPQLN
                     EELAAAFSKHLGTDAENWKEIELEVIMRRIIAQATSRFIVGLPLCRDDGYLDLSYKVIL
                     GMVTTIWATLPFPDLIRAITGPIASWQTRRNIARIQEYLEPLYQERISILESRDGPESD
                     PEPQDLFMMMLRFAQKKRPDEYANLGIMTRRVCAANFVAMHQSTVSVTNLILNIIGSDA
                     EFNTTATLRDEITQVMRGTDAKSWTKDTFTRMRKCDSVAREAMRLNFPLGTRGSMRAVL
                     KDGLESPEGIKLQKGTTISWLASCAQVDADRFDNPQKFDPFRFSRASKDDDDDGKSTSS
                     HAKDAFVTTSPQYLPFGHGKHACPGRFMVDLMFKILLAQLLTHYDLGWPEDYQGKQPPS
                     VWQGELSEPPPGARILVKRRKV"
     intron          3444..3500
                     /gene="tens"
                     /number=3
     gene            complement(3501..7498)
                     /gene="tens3"
     mRNA            complement(3501..7498)
                     /gene="tens3"
     exon            3501..7498
                     /gene="tens"
                     /number=4
     CDS             complement(4377..5543)
                     /NRPS_PKS="Domain: PKS_ER (19-154). E-value: 1.8e-15.
                     Score: 48.7. Matches aSDomain:
                     nrpspksdomains_tens3_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GOA:A0JJU0"
                     /db_xref="InterPro:IPR002085"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:A0JJU0"
                     /gene="tens3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 149.3; E-value: 2.5e-45)"
                     /gene_kind="biosynthetic-additional"
                     /product="hypothetical protein"
                     /protein_id="CAL69596.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.4e-12, bitscore:
                     34.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAISSPPLTQKALKVASPDTLHLVTDAPLPTLGQDDSVLIRVVC
                     VAINPVDGKSAEMSPTPGATSGTDFAGIVVALHGDAKSRTETADTIKTGDRVMGFVFGN
                     NPHVLGNGAFAEYVTLPRRFLWRVPDHMSLEAAASLPVGVASVGMALHYLRISMSSLLK
                     AVSRSIAAPSASQPHDGAFDSDANVFILVYGGGTSTGAIAIQILKAAGFHPITCCSSES
                     ASRAKRLGAVATFDYQSATCGRDIRDYTNDSLTLAIDCLSESASMAICYEAMGSAGGRY
                     VSLDPFPVRGCVRRSIVPDWICSFTQFGQSIPWAPPYNLDERPDDHRLAEEWYHLAQKL
                     LDAELIEAPTLEIRSGGLLHVPEGVAAVKLGQIKRRKLVYHISEEALP"
     aSDomain        complement(5082..5486)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tens3_PKS_ER.1"
                     /evalue="1.80E-15"
                     /label="tens3_PKS_ER.1"
                     /locus_tag="tens3"
                     /protein_end="154"
                     /protein_start="19"
                     /score="48.7"
                     /tool="antismash"
                     /translation="DTLHLVTDAPLPTLGQDDSVLIRVVCVAINPVDGKSAEMSPTPGA
                     TSGTDFAGIVVALHGDAKSRTETADTIKTGDRVMGFVFGNNPHVLGNGAFAEYVTLPRR
                     FLWRVPDHMSLEAAASLPVGVASVGMALHYL"
     CDS             join(6225..7498,7612..10836,10956..19176)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (17-455). E-value:
                     1.1e-164. Score: 540.2. Matches aSDomain:
                     nrpspksdomains_tens_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (588-912). E-value: 8.2e-90.
                     Score: 293.0. Matches aSDomain:
                     nrpspksdomains_tens_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (992-1183). E-value: 1.1e-23.
                     Score: 76.3. Matches aSDomain:
                     nrpspksdomains_tens_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (1479-1656). E-value: 1.6e-75.
                     Score: 245.7. Matches aSDomain: nrpspksdomains_tens_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (2208-2380). E-value: 3.3e-51.
                     Score: 165.7. Matches aSDomain:
                     nrpspksdomains_tens_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2506-2578). E-value: 2.1e-11.
                     Score: 35.9. Matches aSDomain:
                     nrpspksdomains_tens_PKS_PP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (2723-3027). E-value:
                     1.6e-48. Score: 157.2. Matches aSDomain:
                     nrpspksdomains_tens_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (3202-3614). E-value:
                     2.9e-87. Score: 284.8. Matches aSDomain:
                     nrpspksdomains_tens_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (3776-3831). E-value:
                     5.9e-11. Score: 34.7. Matches aSDomain:
                     nrpspksdomains_tens_PP-binding.1"
                     /NRPS_PKS="Domain: TD (3896-4149). E-value: 2.1e-49. Score:
                     159.8. Matches aSDomain: nrpspksdomains_tens_TD.1"
                     /codon_start=1
                     /db_xref="GOA:A0JJU1"
                     /db_xref="InterPro:IPR000794"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="InterPro:IPR013217"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="InterPro:IPR016038"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020801"
                     /db_xref="InterPro:IPR020807"
                     /db_xref="InterPro:IPR020841"
                     /db_xref="InterPro:IPR020842"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="UniProtKB/TrEMBL:A0JJU1"
                     /gene="tens"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 223.5; E-value:
                     8.2e-68)"
                     /gene_kind="biosynthetic"
                     /note="tenellin polyketide synthase"
                     /product="nonribosomal peptide synthase"
                     /protein_id="CAL69597.1"
                     /sec_met_domain="PKS_KS (E-value: 8.1e-166, bitscore:
                     540.2, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5.9e-91, bitscore: 293.0,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 6e-47, bitscore:
                     148.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 8.6e-47, bitscore:
                     147.7, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8.1e-94, bitscore:
                     302.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.2e-12, bitscore:
                     34.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 8.6e-27, bitscore:
                     81.9, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPMKQNESESHSVSEPIAIIGSAYRFPGGCNTPSKLWDLLRQPR
                     DILKEIDPERLNLRRYYHPDGETHGSTDVANKAYTLEEDISRFDASFFGISPLEAASMD
                     PQQRTLLEVVYESTETAGIPLDKLRGSLTSVHVGVMTTDWAQMQRRDPETMPQYTATGI
                     ASSIISNRISYIFDLKGASETIDTACSSSLVALHNAARALQSGDCEKAIVAGVNLILDP
                     DPFIYESKLHMLSPDARSRMWDAAANGYARGEGAAAVVLKTLGHALRDGDRIEGVIRST
                     FVNSDGLSSGLTMPSSAAQTALIRQTYRKAGLDPVRDRPQFFECHGTGTKAGDPVEARA
                     ISDAFLPPSHRTNGAATTVDAPLYVGSIKTVVGHLEGCAGLAGLVKVLLSLKHGIIPPN
                     LWFDKLNPEIARYYGPLQIPTKAIPWPKLAPGTPLRASVNSFGFGGTNAHAIIERYDAS
                     QSYCSQWRRNMTEEKTIARTQNNESIEIPVPLVLTAKTGRALWRTVDAYAQHLRQHPKL
                     RVTNLSQFMHSRRSTHRVRASFSGASREELVENMAKFVQAHAADAKSPASQNRIGYSPL
                     HIDPKEAPGILGVFTGQGAQWPAMGRDMMHQSPLFRKTIADCESVLQALPAKDAPVWSL
                     SEELKKDASTSRLGEAEISQPLCTAVQLALVNVLLASGVHFDAVVGHSSGEIAATYASG
                     IINLEAAMQIAYYRGLYAKLARGETDAAGGMMAAGLSMNDAVKLCRLPEFEGRIHVAAS
                     NAPQSVTLSGDKEAIKAAKAKLDADGVFARELKVDTAYHSHHMLPCAEPYLKALLACDI
                     QVSAPTTTPGRKCMWSSSVRGDAELLRHDRNLDSLKGPYWVANMVQTVLFSRAVQSTIW
                     HGGPFDLAVEVGPHPALKGPTEQTLKAVYGSAPLYTGVLSRGANDAVAFSTAIGNIWSH
                     LGPAFVDITGYQSIFSSTCEGHGGGSAAPFISDLPLYPWDHDEEYWRESRISRRHRTGK
                     DESHELLGRRTPDDNEREIRWRNLLKVSELPWTQGHRVLGEVLLPGAAYISMAIEAGRR
                     LALDQGREARLLEVSDVDILRPVVVADNKEGTETLFTVRLLDEYASTGKKSDELITASF
                     SFYIYNSPASTSIVHTCEGRIAVQLGAKLGSEAGANSMPQLPHREPSISNLQQLDCEKL
                     YSVFETIGLEYSGAFRRIVSSSRCLGHATATASWPTTDLNDCYLIHPAILDVAFQTIFV
                     ARAHPDSGQLSSALLPSRIERVRVVPSLAMGSKLQNNENFNAAIDSWALNQTASSLTGN
                     INVYDAESGRALIQVEGFEVRAVGEPDASKDRLLFYETVWGRDISIMGLSDPIRDETSD
                     AMVHNLSEAIERVSLFYVRQLMGELSTADRRQANWYHTRMLAAFDYHLAKVHEETHLHL
                     RPEWLADDWAVIQTIDEAYPDAVELQMLHAVGQNVADVIRGKKHLLEVLRVDNLLDRLY
                     TEDKGMHMANLFLANALEEITFKFPRCKILEIGAGTGATTWAALSAIGEAFDTYTYTDL
                     SVGFFENAVERFSAFRHRMVFRALDIEKDPASQSFDLNSYDIIIATNVLHATRNLGVTL
                     GNVRALLKPGGYLLLNEKTGPESLRATFNFGGLEGWWLAEEKERQLSPLMSPDGWDAQL
                     QKASFSGVDHIVHDVQEDQQDKQQNSMIMSQAVDDTFYARLSPLSEMANLLPMNEPLLI
                     IGGQTTATLKMIKEIQKLLPRQWRHKVRLIASVDHVEAEGLPAHSDVICLQELDRGLFT
                     TAMTSKCLDALKTLFINTRNLLWVTNAQNSSSMTPRASMFRGITRVLDGEVPHIRTQVL
                     GIEPRETPSATARTLLEAFLRLRSDDGRHAGNVDEDGADGSSQQVLWLHEPEAELLSNG
                     TMMVPRVKARKSLNDTYLASTRAISTTVDARCVSVQAVAGPAKMLLRPVEDFAGEHAIS
                     NQTSDSKVHIQVESTLHIPEALDGTCLYLVCGWTRTAETSVPVIALSANNASMVAVESK
                     AVAMIDEVDVKPETLLRVFQHMAMQALDSAVKRHGQGQSTALIYGADEELAKLTSERFA
                     VRESKVYFASSRTFAPGDWLKVQPLLSKFALSQMIPADVEVFIDCLGDTESFDACRTLQ
                     SCLSTTRTVQHRLDACLLSQMSRCSPDALVDAYSYAKTQSNAEFSWNGYVKTFTAAELA
                     GKLSHSLIHSVYMTNWQKKDSILVTVPPLQTRGLFKSDRTYLMVGAAGGLGTSICRWMV
                     RNGARHVVVTSRNPKADPEMLNEAERYGAAVQVVPMDACSKDSVQTVVDMIRATMPPIA
                     GVCNAAMVLRDKLFLDMNVDHMKDVLGPKMQGTEHLDSIFAQEPLDFFVLLSSSAAILN
                     NTGQSNYHCANLYMDSLVTNRRSRGLAASIIHVGHVCDTGYVARLVDDTKVQMSLGTTR
                     VMSVSETDVHHAFAEAVRGGQPDSRSGSHNIIMGIEPPTKPLDLTKRKPVWISDPRLGP
                     CLPFSTLENQMMASEQAAAASAVDSLAQQVSEATTDEEAAVAALKGFATKLEGILLLPL
                     GSIGEDSAGRPVTDLGIDSLVAVEIRTWFLKQLRVDVPVMKILGGSTVGQLSALAAKLA
                     RQDAKKRAQLEEPSGNQPVALPSPPPKDKAGGLNKNGKSPKLPEIAQVDTVVERMEPLV
                     LEASDRGGSSTANLTTSSSVSELDDSLHESTLQSSDNNGESTPSKSSNCNSDSGSDNQA
                     PKEIPSNGFFTQPAATARPNVLREAPMSPAQSRIWFLSKHIAEPDAYNMVFHYRVRGPL
                     SMVRLRHALQTVTNHHECLCMCFYASADNGQPMQGLLASSAFQMTHVPGGEEQDVQREL
                     RKLKTRVWSVESGQTLELVVLGPRPGTAAAAEEEEEEFSLLFGYHHIVMDAISFYIFLA
                     DLDKAYRMLPLDKASAGSHLDLAAHQRQQERAGAWEESLEFWRAEFETIPEMLPSLSVA
                     LPTLHRGAVGTHRVLRELAHEQGGDAAIKKMCKHLRVSPFNLHIAVLQVVIARLASIED
                     VCVGIVDANRSDSRASRMVGCFVNMLPVRSRILPTATLADVARAASSKALAAFAHGQVP
                     LDSILDKVKAPRPAGSTPLFQVALNYRPAAAIASKQALGGECEMELLADDFKDAENPFE
                     ISVLVSEMSGGRIAVEVVCQKSRYTMQATEALLDAYLNVLAGFLSDSAQSVGDCVVHDQ
                     SKVEHALDLGRGAQKSFGWPRTLSERVMSICQQHSTKSAIKDGRNELSYAQLASRVNRT
                     ASAILGTGCSVGSRIAVLCNPSIDAIVAMLAILHIGGVYVPLDTSLPEARHQSLASNCT
                     PSLIISHAATRERAHKLSAAISAPGHEPARELTLDDLSPPEETGYMAPLNAEPNAPAIL
                     LYTSGSTGTPKGVLLTQANFGNHIALKTDILGLQRGECVLQQSSLGFDMSLVQVFCALA
                     NGGCLVIVRQDVRRDPVELTTLMTQHKVSLTIATPSEYLAWLQYGSDALAQATSWKNLC
                     MGGEPIPPLLKDELRRRLERKDLVVTNCYGPTETTAAISFQSVALDSEHGHELPGESEL
                     AQYAVGKALPNYSIRIRDSAGGAWLPVNHTGEIVIGGAGVALGYLDMPEETRARFLQTP
                     GEEDGMMLYRTGDKGRLLSDGTLLCFGRITGDYQVKLRGLRIELGEVEAALLQASHGLI
                     HTAVVSRRGDVLVAHCARSHESSRETTGGGEQQDATAILRRVSELLPQYSVPAAIALLP
                     SLPTNANGKLDRKAIAALPLSPQDEAAAATSPSNNNINNNTPSGGGGEKMTVRQGELRL
                     LWERVLPRDAATTTTNSVRITPESDFFLRGGNSLLLMKLQAAIRESMGVRVSTKALYQA
                     STLSGMARCVAEQRSDDDEAEEDIDWAAEVAVPPSMLAQIEKLQHSSASSSSSSSSSSS
                     AGSSSTQRPRKTSGLEILLTGATGFLGGQLLERLVQSPRVSTVHCVAVPVDEQSLLEPF
                     LQQQADGTRRKVRCYIGNLAAPALGLTAADQTALSQTADVIVHAGSMGHCLNTYATLAA
                     PNFASTRHLCSLALSRSPPIPLAFASSNRVALLTGSTAPPPASAAAFPPPPGAQGFTAS
                     KWASEAFLEKLAASIMTSKTKSTTTTTTTTVPWRVSIHRPCALISDRAPNSDALNAILR
                     YSTSMRCVPSLPEHRAEGYLDFGQVDKVVEEMVGDILGLADERQQEGPAVVYRHHSGGV
                     KVPIHEFREHMESVYGGRFESVELGQWIVRAVDAGMDPLISAYLETFLEGDASMVFPYM
                     GEQAV"
     aSDomain        join(6276..7498,7612..7702)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tens_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.10E-164"
                     /label="tens_PKS_KS.1"
                     /locus_tag="tens"
                     /protein_end="455"
                     /protein_start="17"
                     /score="540.2"
                     /tool="antismash"
                     /translation="IAIIGSAYRFPGGCNTPSKLWDLLRQPRDILKEIDPERLNLRRYY
                     HPDGETHGSTDVANKAYTLEEDISRFDASFFGISPLEAASMDPQQRTLLEVVYESTETA
                     GIPLDKLRGSLTSVHVGVMTTDWAQMQRRDPETMPQYTATGIASSIISNRISYIFDLKG
                     ASETIDTACSSSLVALHNAARALQSGDCEKAIVAGVNLILDPDPFIYESKLHMLSPDAR
                     SRMWDAAANGYARGEGAAAVVLKTLGHALRDGDRIEGVIRSTFVNSDGLSSGLTMPSSA
                     AQTALIRQTYRKAGLDPVRDRPQFFECHGTGTKAGDPVEARAISDAFLPPSHRTNGAAT
                     TVDAPLYVGSIKTVVGHLEGCAGLAGLVKVLLSLKHGIIPPNLWFDKLNPEIARYYGPL
                     QIPTKAIPWPKLAPGTPLRASVNSFGFGGTNAHAIIERY"
     aSModule        6276..14190
                     /complete
                     /domains="nrpspksdomains_tens_PKS_KS.1"
                     /domains="nrpspksdomains_tens_PKS_AT.1"
                     /domains="nrpspksdomains_tens_PKS_DH.1"
                     /domains="nrpspksdomains_tens_cMT.1"
                     /domains="nrpspksdomains_tens_PKS_KR.1"
                     /domains="nrpspksdomains_tens_PKS_PP.1"
                     /iterative
                     /locus_tags="tens"
                     /monomer_pairings="pk -> Me-pk"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       6762..6809
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0001"
                     /evalue="7.50E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="tens"
                     /protein_end="195"
                     /protein_start="179"
                     /score="15.1"
                     /tool="antismash"
                     /translation="GASETIDTACSSSLVA"
     CDS_motif       6951..6989
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0002"
                     /evalue="2.00E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="tens"
                     /protein_end="255"
                     /protein_start="242"
                     /score="11.4"
                     /tool="antismash"
                     /translation="WDAAANGYARGEG"
     CDS_motif       7191..7235
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0003"
                     /evalue="1.50E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="tens"
                     /protein_end="337"
                     /protein_start="322"
                     /score="11.1"
                     /tool="antismash"
                     /translation="FECHGTGTKAGDPVE"
     intron          7499..7611
                     /gene="tens"
                     /number=4
     exon            7612..10836
                     /gene="tens"
                     /number=5
     CDS_motif       8102..8152
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0004"
                     /evalue="2.00E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="tens"
                     /protein_end="605"
                     /protein_start="588"
                     /score="14.0"
                     /tool="antismash"
                     /translation="VFTGQGAQWPAMGRDMM"
     aSDomain        8102..9073
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tens_PKS_AT.1"
                     /evalue="8.20E-90"
                     /label="tens_PKS_AT.1"
                     /locus_tag="tens"
                     /protein_end="912"
                     /protein_start="588"
                     /score="293.0"
                     /specificity="substrate consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFTGQGAQWPAMGRDMMHQSPLFRKTIADCESVLQALPAKDAPVW
                     SLSEELKKDASTSRLGEAEISQPLCTAVQLALVNVLLASGVHFDAVVGHSSGEIAATYA
                     SGIINLEAAMQIAYYRGLYAKLARGETDAAGGMMAAGLSMNDAVKLCRLPEFEGRIHVA
                     ASNAPQSVTLSGDKEAIKAAKAKLDADGVFARELKVDTAYHSHHMLPCAEPYLKALLAC
                     DIQVSAPTTTPGRKCMWSSSVRGDAELLRHDRNLDSLKGPYWVANMVQTVLFSRAVQST
                     IWHGGPFDLAVEVGPHPALKGPTEQTLKAVYGSAPLYTGVLSR"
     CDS_motif       8354..8458
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0005"
                     /evalue="3.90E-09"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="tens"
                     /protein_end="707"
                     /protein_start="672"
                     /score="29.0"
                     /tool="antismash"
                     /translation="GVHFDAVVGHSSGEIAATYASGIINLEAAMQIAYY"
     CDS_motif       8486..8551
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0006"
                     /evalue="7.40E+00"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="tens"
                     /protein_end="738"
                     /protein_start="716"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="GETDAAGGMMAAGLSMNDAVKL"
     aSDomain        9314..9886
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tens_PKS_DH.1"
                     /evalue="1.10E-23"
                     /label="tens_PKS_DH.1"
                     /locus_tag="tens"
                     /protein_end="1183"
                     /protein_start="992"
                     /score="76.3"
                     /tool="antismash"
                     /translation="HELLGRRTPDDNEREIRWRNLLKVSELPWTQGHRVLGEVLLPGAA
                     YISMAIEAGRRLALDQGREARLLEVSDVDILRPVVVADNKEGTETLFTVRLLDEYASTG
                     KKSDELITASFSFYIYNSPASTSIVHTCEGRIAVQLGAKLGSEAGANSMPQLPHREPSI
                     SNLQQLDCEKLYSVFETIGLEYSGAFRR"
     CDS_motif       9398..9475
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0007"
                     /evalue="5.20E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="tens"
                     /protein_end="1046"
                     /protein_start="1020"
                     /score="31.8"
                     /tool="antismash"
                     /translation="WTQGHRVLGEVLLPGAAYISMAIEAG"
     aSDomain        join(10775..10836,10956..11424)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tens_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="1.60E-75"
                     /label="tens_cMT.1"
                     /locus_tag="tens"
                     /protein_end="1656"
                     /protein_start="1479"
                     /score="245.7"
                     /tool="antismash"
                     /translation="EITFKFPRCKILEIGAGTGATTWAALSAIGEAFDTYTYTDLSVGF
                     FENAVERFSAFRHRMVFRALDIEKDPASQSFDLNSYDIIIATNVLHATRNLGVTLGNVR
                     ALLKPGGYLLLNEKTGPESLRATFNFGGLEGWWLAEEKERQLSPLMSPDGWDAQLQKAS
                     FSGVDHIVHDVQED"
     intron          10837..10956
                     /gene="tens"
                     /number=5
     CDS_motif       13081..13179
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0008"
                     /evalue="7.80E-16"
                     /label="PKSI-KR_m1"
                     /locus_tag="tens"
                     /protein_end="2241"
                     /protein_start="2208"
                     /score="50.6"
                     /tool="antismash"
                     /translation="TYLMVGAAGGLGTSICRWMVRNGARHVVVTSRN"
     aSDomain        13081..13596
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tens_PKS_KR.1"
                     /evalue="3.30E-51"
                     /label="tens_PKS_KR.1"
                     /locus_tag="tens"
                     /protein_end="2380"
                     /protein_start="2208"
                     /score="165.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="TYLMVGAAGGLGTSICRWMVRNGARHVVVTSRNPKADPEMLNEAE
                     RYGAAVQVVPMDACSKDSVQTVVDMIRATMPPIAGVCNAAMVLRDKLFLDMNVDHMKDV
                     LGPKMQGTEHLDSIFAQEPLDFFVLLSSSAAILNNTGQSNYHCANLYMDSLVTNRRSRG
                     LAASIIHVG"
     CDS_motif       13450..13560
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0009"
                     /evalue="1.70E-16"
                     /label="PKSI-KR_m4"
                     /locus_tag="tens"
                     /protein_end="2368"
                     /protein_start="2331"
                     /score="52.7"
                     /tool="antismash"
                     /translation="LDFFVLLSSSAAILNNTGQSNYHCANLYMDSLVTNRR"
     aSDomain        13975..14190
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tens_PKS_PP.1"
                     /evalue="2.10E-11"
                     /label="tens_PKS_PP.1"
                     /locus_tag="tens"
                     /protein_end="2578"
                     /protein_start="2506"
                     /score="35.9"
                     /tool="antismash"
                     /translation="ALKGFATKLEGILLLPLGSIGEDSAGRPVTDLGIDSLVAVEIRTW
                     FLKQLRVDVPVMKILGGSTVGQLSALA"
     aSDomain        14626..15537
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tens_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.60E-48"
                     /label="tens_Condensation_LCL.1"
                     /locus_tag="tens"
                     /protein_end="3027"
                     /protein_start="2723"
                     /score="157.2"
                     /tool="antismash"
                     /translation="EAPMSPAQSRIWFLSKHIAEPDAYNMVFHYRVRGPLSMVRLRHAL
                     QTVTNHHECLCMCFYASADNGQPMQGLLASSAFQMTHVPGGEEQDVQRELRKLKTRVWS
                     VESGQTLELVVLGPRPGTAAAAEEEEEEFSLLFGYHHIVMDAISFYIFLADLDKAYRML
                     PLDKASAGSHLDLAAHQRQQERAGAWEESLEFWRAEFETIPEMLPSLSVALPTLHRGAV
                     GTHRVLRELAHEQGGDAAIKKMCKHLRVSPFNLHIAVLQVVIARLASIEDVCVGIVDAN
                     RSDSRASRMVGCFVNMLPVRSRI"
     aSModule        14626..18903
                     /complete
                     /domains="nrpspksdomains_tens_Condensation_LCL.1"
                     /domains="nrpspksdomains_tens_AMP-binding.1"
                     /domains="nrpspksdomains_tens_PP-binding.1"
                     /domains="nrpspksdomains_tens_TD.1"
                     /final_module
                     /locus_tags="tens"
                     /monomer_pairings="Tyr -> Tyr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       14689..14802
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0010"
                     /evalue="2.60E-08"
                     /label="C2_LCL_024-062"
                     /locus_tag="tens"
                     /protein_end="2782"
                     /protein_start="2744"
                     /score="26.3"
                     /tool="antismash"
                     /translation="DAYNMVFHYRVRGPLSMVRLRHALQTVTNHHECLCMCF"
     CDS_motif       15040..15096
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0011"
                     /evalue="2.00E-04"
                     /label="C3_DCL_135-156"
                     /locus_tag="tens"
                     /protein_end="2880"
                     /protein_start="2861"
                     /score="14.0"
                     /tool="antismash"
                     /translation="YHHIVMDAISFYIFLADLD"
     CDS_motif       15439..15528
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0012"
                     /evalue="2.60E-09"
                     /label="C5_LCL_267-296"
                     /locus_tag="tens"
                     /protein_end="3024"
                     /protein_start="2994"
                     /score="29.5"
                     /tool="antismash"
                     /translation="DVCVGIVDANRSDSRASRMVGCFVNMLPVR"
     CDS_motif       15586..15696
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0013"
                     /evalue="1.20E-08"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="tens"
                     /protein_end="3080"
                     /protein_start="3043"
                     /score="27.2"
                     /tool="antismash"
                     /translation="ALAAFAHGQVPLDSILDKVKAPRPAGSTPLFQVALNY"
     aSDomain        16063..17298
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tens_AMP-binding.1"
                     /evalue="2.90E-87"
                     /label="tens_AMP-binding.1"
                     /locus_tag="tens"
                     /protein_end="3614"
                     /protein_start="3202"
                     /score="284.8"
                     /specificity="substrate consensus: Tyr"
                     /tool="antismash"
                     /translation="CQQHSTKSAIKDGRNELSYAQLASRVNRTASAILGTGCSVGSRIA
                     VLCNPSIDAIVAMLAILHIGGVYVPLDTSLPEARHQSLASNCTPSLIISHAATRERAHK
                     LSAAISAPGHEPARELTLDDLSPPEETGYMAPLNAEPNAPAILLYTSGSTGTPKGVLLT
                     QANFGNHIALKTDILGLQRGECVLQQSSLGFDMSLVQVFCALANGGCLVIVRQDVRRDP
                     VELTTLMTQHKVSLTIATPSEYLAWLQYGSDALAQATSWKNLCMGGEPIPPLLKDELRR
                     RLERKDLVVTNCYGPTETTAAISFQSVALDSEHGHELPGESELAQYAVGKALPNYSIRI
                     RDSAGGAWLPVNHTGEIVIGGAGVALGYLDMPEETRARFLQTPGEEDGMMLYRTGDKGR
                     LLSDGTLLCFGRI"
     CDS_motif       16237..16278
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0014"
                     /evalue="3.50E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="tens"
                     /protein_end="3274"
                     /protein_start="3260"
                     /score="11.0"
                     /tool="antismash"
                     /translation="LAILHIGGVYVPLD"
     CDS_motif       16495..16551
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0015"
                     /evalue="4.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="tens"
                     /protein_end="3365"
                     /protein_start="3346"
                     /score="22.4"
                     /tool="antismash"
                     /translation="AILLYTSGSTGTPKGVLLT"
     CDS_motif       17092..17115
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0016"
                     /evalue="1.70E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="tens"
                     /protein_end="3553"
                     /protein_start="3545"
                     /score="-0.1"
                     /tool="antismash"
                     /translation="AGGAWLPV"
     CDS_motif       17110..17199
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0017"
                     /evalue="3.30E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="tens"
                     /protein_end="3581"
                     /protein_start="3551"
                     /score="35.4"
                     /tool="antismash"
                     /translation="PVNHTGEIVIGGAGVALGYLDMPEETRARF"
     CDS_motif       17305..17355
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0018"
                     /evalue="2.60E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="tens"
                     /protein_end="3633"
                     /protein_start="3616"
                     /score="19.9"
                     /tool="antismash"
                     /translation="DYQVKLRGLRIELGEVE"
     aSDomain        17785..17949
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tens_PP-binding.1"
                     /evalue="5.90E-11"
                     /label="tens_PP-binding.1"
                     /locus_tag="tens"
                     /protein_end="3831"
                     /protein_start="3776"
                     /score="34.7"
                     /tool="antismash"
                     /translation="TNSVRITPESDFFLRGGNSLLLMKLQAAIRESMGVRVSTKALYQA
                     STLSGMARCV"
     aSDomain        18145..18903
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tens_TD.1"
                     /evalue="2.10E-49"
                     /label="tens_TD.1"
                     /locus_tag="tens"
                     /protein_end="4149"
                     /protein_start="3896"
                     /score="159.8"
                     /tool="antismash"
                     /translation="ILLTGATGFLGGQLLERLVQSPRVSTVHCVAVPVDEQSLLEPFLQ
                     QQADGTRRKVRCYIGNLAAPALGLTAADQTALSQTADVIVHAGSMGHCLNTYATLAAPN
                     FASTRHLCSLALSRSPPIPLAFASSNRVALLTGSTAPPPASAAAFPPPPGAQGFTASKW
                     ASEAFLEKLAASIMTSKTKSTTTTTTTTVPWRVSIHRPCALISDRAPNSDALNAILRYS
                     TSMRCVPSLPEHRAEGYLDFGQVDKVVEEMV"
     CDS_motif       18148..18204
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_tens_0019"
                     /evalue="5.40E-01"
                     /label="PKSI-KR_m1"
                     /locus_tag="tens"
                     /protein_end="3916"
                     /protein_start="3897"
                     /score="3.0"
                     /tool="antismash"
                     /translation="LLTGATGFLGGQLLERLVQ"
ORIGIN
        1 atgctgcccc tcctagacag cgtgagcctc ccatacctca tcctgtcggc atgtctttct
       61 gtcatactgc tgcgcagatt cctagctcac gacaagggag gatccaagtc catcgcacaa
      121 ggctgtttgc ctgagccacg tttgcgtcaa tgggatccta ttttcggttt cggcattgtc
      181 attagccagg caagagcctt gcggggacat cgctacctcg aatggctccg agacctccac
      241 gccagcatgc ctcatacaaa gaccttttct gcaaactatg gcggctaccg gtggatcttt
      301 tccattgagc cagagattct gaaagccgtc tatgctacca atttacaaaa ctttggcgtc
      361 gagcccatca ggcagcaccc tcctggattt caaccatttg cccacaaggg tgtcagcacc
      421 agtgatggcg acgactggag cttcagtcgg accttgatca agcccttttt cgaacgaagt
      481 gtctatatca gtactgatcg tatcaagcca tttgcggaca aattcatgac actgcttcct
      541 gatgatggag agacttttga catacagcct ctgcttcaac gatgggtacg tgagctgctg
      601 tgcccacatc ataaaacaac gtactgagaa atttttgaac aacttttagt ttctcgacat
      661 tacatctgaa ttcatttttg gcaaatctca ggattccatg acgcatgccg accgtgctga
      721 agtcacgtgg gcaatggccg atgttctccg aggcggccgt caacgagcgc agactcacag
      781 aattctctgg gcgtttaatt gggattggtg gtttgaggcc gtggaaaagg tacacggttt
      841 tctgaatcca tacattcggt cgactttgaa ggaactcgag gaacgacagc agcgcatcaa
      901 agatggcctc ccagtcgacg aggagagaac agacttgctc tggtcaatgg ccacgatgct
      961 tcccgacgag gaagagctga ggtctcaagt ctgcctcatc tttgtcccaa acaatgacac
     1021 gacatcaatg tttattggcc attgcctgta cttcctcgcc cgcaactcga acgcgtggaa
     1081 gagactgaga gatgaagtgg atgcggtcgg cgatgcgccc attacttttg agatgctcag
     1141 aaacatgaag tacctcaacg gcatcttgaa tgaaagtatg aaacccaatc ccctctcatc
     1201 tagctgaccc tagcactgac cacactttgc acaccagcgc accgtttgat acccaacaat
     1261 gtgactcagg tccgagctgc cctctcagat gtggtactgc cgcttggggg aggaccaaac
     1321 ggcaaagccc ctctcgacgt tcgcaaaggt gatatcgttt cggtgacaaa gactgtcatg
     1381 tatcgggacc ccgaacagtg gggtccggat gccaacgagt atcggcctga acgctgggac
     1441 ggcatgcgag gcggctggca ctttttaccc tatgggggcg ggccgagaag atgcccagcg
     1501 caaatgatgg tccagaatga gtctgcgtat atgcttttcc ggttggcgca aaagtatagc
     1561 accattgtgg cgcgggaccc ggagccgttt agggccagaa tgcgtattgg tccttctagc
     1621 atgcatggag tcaagattgc gttttacaag taacttttag gatactctta cttgaatgaa
     1681 atctgcttaa agatgaagtt gaagtaatgt aatgggctag tttggtgact tgtgtggtgc
     1741 cagcgggaac tttgttttca acgaccattt caagcagcat gagcgtcgca agtccaccag
     1801 aatgatacca gttttctcag actgctttgg tcaagactgt ccttcacaaa gacggcaggt
     1861 gtgttagcaa tatgccaaag tctcaccaag gctcggatat taaagtagca ctagtgacaa
     1921 tgggttacga aagttgccaa agtacacaat tagacactat gcatagccag tctgtgaata
     1981 gtgtagaatt ctagcagata acgatgccaa agtacaagta caagaaaaaa agtagaaaaa
     2041 gaacaaaaga aaaaacaaaa ctaaactttg cgcctcttga ccagaatacg cgcgccagga
     2101 ggaggctccg ataattctcc ctgccaaaca ctgggcggct gcttgccctg gtaatcctcc
     2161 ggccagccaa ggtcgtagtg tgtcagaagc tgggccagga gaatcttgaa catcaagtcg
     2221 accatgaacc ttcccgggca ggcgtgtttt ccatggccaa agggcaagta ctgcggcgaa
     2281 gtcgtgacaa aagcatcctt ggcatgacta ctagtactct tgccgtcgtc gtcgtcgtct
     2341 ttggacgctc tcgaaaagcg aaaggggtca aacttttgcg gattgtcgaa ccggtcggca
     2401 tcgacctgtg cgcaagaggc cagccaggat atggtggttc ccttttggag cttgatgcct
     2461 tcggggctct cgaggccgtc cttgagaacg gcgcgcatgg agccgcgcgt acccagggga
     2521 aagttgagac gcatcgcttc acgcgcgacg ctgtcgcatt tcctcatgcg cgtaaacgta
     2581 tccttggtcc agctttttgc gtctgtacct ctcattactt gggtgatttc atctcgaagt
     2641 gtggctgtgg tgttgaattc ggcgtctgag ccgatgatgt tgaggatgag atttgtcacg
     2701 gaaacggtgg actggtgcat cgcgacaaag ttggccgcgc acacgcgtcg cgtcatgatg
     2761 ccgaggttgg catactcgtc tgggcgcttt ttttgtgcga agcggagcat catcatgaag
     2821 aggtcctgtg gctcagggtc gctttccggg ccgtctctgc tttcgaggat ggagatgcgc
     2881 tcttggtaca gaggctcgag gtactcttga atcctcgcaa tatttcgacg tgtctgccag
     2941 ctggctatag gtccagttat tgcgcggatc aagtcgggaa atgggagggt agcccagatt
     3001 gtagtcacca tgccgagaat gaccttgtaa gagagatcaa gatagccatc gtctcggcaa
     3061 agcggcaggc cgacaataaa tcggcttgtt gcctgggcaa tgatcctcct cataatgact
     3121 tctagctcaa tctctttcca attctccgca tcagttccca ggtgttttga aaaagcggca
     3181 gctagctctt cattcagctg ggggataaga ttttgcagga tggagcttag atgagccttg
     3241 acgagatcga gctgccacgg gtcctcccag tatctgccat gtccaaggct gtacttggtt
     3301 tgattgagct ctgaaaatgc ctttttgatg ctcagcgagt cgtcgggctg cgacatggcc
     3361 caattcattg cactttcggg catgatcatg gcagtgtgaa cacccatgga cggaactaga
     3421 accgctttgc cctttttggc atactatgta gcgttagttt aattaattaa ttacatccaa
     3481 gattatttca tctagtgact tgcagtatga taggcttcat cgaaaagagc cgcgcagtcg
     3541 ttgtagtatc tcaatctgtt ggaaagggaa aaccatcttc gctgtggagg ttctcctgcc
     3601 aatggcaacg cagggtaaaa gggcttatga ttgagcttcc aaaagagtag agcaatgctg
     3661 agaaatccca aaacgcccgc cactttttcg tagtagccaa gctgggctac catggacatt
     3721 gcctggaaaa gcgccatttc ggttgtcgac aaagcgtcga cagtacgtca gtgcgtaaca
     3781 agaatggcac ttcaaatagc acattatgga aggaaatgtg gaaaaatccc aaaggtaggg
     3841 tataataaaa accacacttg tatggatcgg caacaaatca ctggaacatc cggaatatta
     3901 tgcagcctca cggagaattg cgggcgctac tggagtggca gcattctgca actgtttgat
     3961 ctgatatgtt gtgtctcgct gttccacaat tctataggtt tattccgtga ctgttgagtt
     4021 gcagaagtta ctacagtcat caactacagt catcaaggaa ggtttacaat atgtgcagat
     4081 caaaacagtg gcgcagtgcc ggtcgagtac gctacttggc tacgcactag caacgccgcg
     4141 atttttagat tattaatttc gtcacaggaa ttaatttcgt cgcgggaatt aatttcgtcg
     4201 caggacaaaa taaagcaact attcaagaaa ctcagagcca agactgttta tttgattgtg
     4261 acagttttac tattcgcttg ccctcaggag cctaatcatc ttcgctagct ggccgaagca
     4321 agcgcaggat tgcaacaatg cccaacacat ctcacattcc aaggtatagc atcaactcag
     4381 ggcagcgcct cctctgaaat atgataaacc agcttccgac gcttaatctg gcccagtttg
     4441 acagcagcta ctccttctgg tacatggagc agcccaccgc ttcttatttc tagggtaggc
     4501 gcctcaatca actcggcatc caacagtttc tgtgccagat gataccactc ctcggcaagg
     4561 cgatgatcat ccggtctctc atcaagatta tatggcgggg cccaaggtat ggactgcccg
     4621 aattgcgtaa aggagcatat ccagtccggc acgatgcttc gacgcacaca gccgcgcacc
     4681 gggaacgggt ccagtgagac gtagcgtccg cccgcgcttc ccatggcttc gtagcatatg
     4741 gccattgagg ctgactcact cagacagtca atggcgagcg tcagagagtc attcgtgtag
     4801 tcgcgaatgt cccggccaca tgttgctgat tgataatcga atgtggcgac cgcacctaga
     4861 cgtttggcac ggcttgcaga ctcggatgag cagcaggtaa tggggtggaa accagcagct
     4921 ttgagaatct gtatagctat agctccagtc gaggtaccgc ctccatagac taggatgaag
     4981 acgttggcgt cgctgtcaaa agcaccgtca tgaggttgag atgcggatgg agccgcaatg
     5041 gatctcgaca ctgcttttag cagggaagac atggaaatgc gcagataatg cagcgccatg
     5101 ccaactgatg caactccaac tggtagggag gctgccgctt ccagagacat gtggtcaggc
     5161 acacgccaga ggaatcgacg cggcaaggtg acgtactcgg caaaggcgcc attaccgagt
     5221 acgtgcgggt tgttgccaaa gacaaatccc atgacgcgat caccagtctt gattgtgtct
     5281 gctgtttcgg tcctgctctt tgcatcaccg tgtagagcga ccacgatgcc ggcaaagtct
     5341 gttccgctgg tagcgccagg cgtaggagac atttctgccg acttgccatc gaccgggttg
     5401 atggcaacgc agacgactcg gatcaagact gaatcatcct gcccaagcgt gggaagagga
     5461 gcatccgtaa caagatggag agtatcggga ctggctactt tgagagcctt ttgagtgagt
     5521 ggtggggaag agatggctgc catgatgggt tgaatggctg tccttgtgtt gatcgtaatc
     5581 acgaatgaat ctcaagcaga ctcgagactc ggtaagcgat gcgattatgt aagagtattt
     5641 tataactcat acaaggccgt tttgagctga atgtggtgga acctattttg ccggcttgtg
     5701 tcgacactcc gaacgtatgg gtcagcattg acgaggctcg gagcggagaa ttccacggtg
     5761 ctgacaagga ttcaaagagg atacgcgggt ggatttccgc cggagttcat gtctgtctta
     5821 cgtttgagtc aatgtttcgg ggaaaaagac cgggttcgct gcagccttgc ctgaacgcct
     5881 cgtcccaata ttgccacgtg ggatgaagag gcttggctga tgcccgttta tactcacgga
     5941 caggcacgga atatgttgtt ggctgaggtc tcgacaagaa agatagggtg gaaagaaaca
     6001 aagtctcgag tacactaata tagaaagttc tctaggtaat tcatttcaac aaaagtcagc
     6061 aaagtgtgat tactgcatgt attgcctatt acccatgcaa gttcaaccat tctacaaccg
     6121 ccctttatca tctttcgttt agcaaagtgt atctacatat gcccctttat tctctttgat
     6181 tcagcaaaaa gtagccctac gtcgaaaact gcaacactgt gagcatgtca cccatgaagc
     6241 agaacgaatc agagtcacac tctgtgtctg aaccgattgc cattatcggc tctgcgtatc
     6301 ggttcccagg tggttgcaat accccatcca agctctggga ccttctccgg caaccgcgag
     6361 atatcctaaa ggagattgac cctgaacgtc ttaatctgag acgctattat catcctgatg
     6421 gcgagaccca cggttcgaca gatgtcgcga acaaagccta caccctcgag gaagacatta
     6481 gccgctttga tgcctccttt ttcggcatta gccccctcga ggcggcaagc atggatccgc
     6541 aacagcggac actcctcgag gtagtatacg agtcgacaga aacggcaggt attccactgg
     6601 acaagctgcg cggctccttg acgtcggtcc atgtgggcgt catgacgacc gactgggccc
     6661 agatgcagcg gcgcgatcca gagaccatgc cgcagtatac ggccacgggc atcgcgagca
     6721 gcatcatctc caatcgcatc tcgtacattt tcgacctcaa gggtgcttcc gagacgattg
     6781 acacggcctg ctccagctcg ctcgtggcgc tgcacaatgc cgcgcgcgcg ctgcaaagcg
     6841 gcgactgcga aaaagccatt gtcgctggcg tcaacctcat cctggaccct gatcccttca
     6901 tctacgagtc caagctgcac atgctgtctc cagacgcgcg gtcacgcatg tgggacgcgg
     6961 cggccaacgg ctacgcgcgc ggcgagggtg ccgcggctgt tgtactcaag acgcttggcc
     7021 acgctctccg agacggcgac cggattgaag gagtcattcg cagcacgttt gtcaactcgg
     7081 acggcttgag ctccgggctg accatgccgt cgtcggcggc gcagacggcg ctcatccgcc
     7141 agacatatcg caaagccggc ctcgacccgg tcagggaccg accgcagttt ttcgaatgcc
     7201 acggcactgg cacaaaggcg ggcgatccgg tcgaggcgcg ggccattagc gatgctttcc
     7261 tgccccccag ccacaggacc aatggtgcag ctactacagt cgacgctcct ctgtatgtgg
     7321 gctcaatcaa gacggtggtt gggcatttgg aagggtgcgc cggcctggct ggtcttgtca
     7381 aggtgcttct cagcctcaaa cacggcatca ttccgcccaa cctctggttc gataagctga
     7441 atccagagat tgcgcgctac tatgggccac ttcagattcc tacaaaagcg ataccgtggt
     7501 aagttttttt tttttttttt ctttttcttt tacatgtata catgtccttt tttaccactc
     7561 tatgaatgac ttttctgggc aatgactgat acaaaagttt acatataata ggcccaagtt
     7621 ggctcctggt acaccgttgc gtgctagtgt gaatagtttt ggattcggag gaaccaatgc
     7681 ccacgccatc attgagcgct acgatgctag ccagagctac tgctcacagt ggcgacgaaa
     7741 tatgaccgag gaaaagacca ttgccagaac gcaaaacaat gaaagtatcg agattcctgt
     7801 tccgctggtt cttacagcca aaacggggcg cgctttgtgg cgaaccgtag atgcatatgc
     7861 gcagcatctg aggcagcatc ccaagcttag ggtcacgaat ctgagccagt ttatgcactc
     7921 gaggcgatcg actcaccgag ttcgagccag cttctcgggc gcatctcgtg aggagcttgt
     7981 cgaaaacatg gccaaatttg tccaagctca tgctgccgac gccaaatcac cggcctcgca
     8041 gaatcgcatc ggctactccc cgctgcacat tgacccgaaa gaagctcccg gcatccttgg
     8101 tgtattcacc ggacaaggag cacagtggcc agcaatgggc cgcgacatga tgcaccagtc
     8161 gccactgttt cgaaagacta ttgcagactg cgagtcggtc ttgcaggccc tccctgcaaa
     8221 agacgcccct gtgtggtcct tgtctgaaga gttgaaaaag gatgcatcga cgtctcggct
     8281 gggagaagca gagatttccc agccgctatg tacagctgtg caactggctc tggtcaatgt
     8341 cctccttgcg tctggcgtcc attttgatgc agtcgtcggc cattcgtctg gcgaaattgc
     8401 agcaacctat gcgagcggca tcatcaatct agaggccgca atgcagattg cctattatcg
     8461 cggcctctat gccaagcttg cgcgaggtga aactgacgcg gccggcggta tgatggcagc
     8521 tgggctctca atgaatgacg ccgtcaaact ctgccgtcta cccgagtttg agggccgcat
     8581 tcacgtcgcc gcaagcaacg cgccccaaag tgtcacgctt tccggagaca aggaggcgat
     8641 caaagccgcc aaggccaagc tcgacgctga cggtgtcttt gcgcgagagt taaaggtgga
     8701 cacggcgtac cactcgcatc acatgcttcc gtgcgctgaa ccgtacctga aagcgcttct
     8761 tgcttgtgat atccaagtca gcgctccgac gacgacgccc gggaggaaat gtatgtggag
     8821 ctcgagcgta cgaggagacg ccgagctgct gcgtcatgac agaaacctgg atagtctgaa
     8881 agggccgtat tgggttgcca acatggtgca aacagtccta ttctcccgcg ctgttcagtc
     8941 caccatctgg cacggcggcc cattcgactt ggctgttgaa gttgggccgc accctgctct
     9001 caagggcccg accgagcaga ctctcaaggc cgtatatggc tctgctccat tgtacactgg
     9061 ggttttgagc cgtggtgcca acgatgcggt cgcattctcc acggctattg gaaacatttg
     9121 gtcgcacctg gggccggcct ttgtcgacat cacaggctac cagtcgatat tttcaagtac
     9181 ttgcgaggga catggcggcg gctcagcagc tcccttcatc tcggatctac cactataccc
     9241 gtgggaccac gacgaagagt actggcgcga gtctcgcatc tctcggcgtc atcgcacagg
     9301 caaagacgag agccacgagc tgctcggacg ccgcacgccc gatgacaacg agcgcgagat
     9361 tcgctggcgc aacctgctca aggtcagcga gctgccctgg acgcagggcc acagagtcct
     9421 cggcgaggtc ttgctgcctg gagccgctta cattagcatg gcaatcgagg ctggtcgacg
     9481 tctggcactt gatcaaggca gggaagcccg tctccttgag gtgtctgatg tcgacattct
     9541 ccgccctgtt gtagtcgccg acaacaagga aggcaccgag acactattca cagtgcgact
     9601 gctcgatgaa tacgcctcga ctgggaaaaa aagcgacgag ttaatcacgg catcattttc
     9661 attttacatt tataacagcc ctgccagcac atccattgtt catacctgcg agggtcgcat
     9721 tgccgtccaa cttggcgcga agctcggttc cgaagcggga gcgaacagca tgccgcagct
     9781 gccacacaga gagccatcga tttccaactt gcagcaactt gactgcgaga agctctattc
     9841 ggtgtttgag actataggct tggagtactc tggggctttc cgacgcatcg tcagcagtag
     9901 ccggtgtcta gggcatgcga cagccaccgc ttcttggccc actacagatc tgaatgactg
     9961 ctaccttatt caccctgcca tcttggatgt tgcgtttcag accatttttg ttgcgcgcgc
    10021 acaccctgac agcgggcagt tgagctctgc attgctgcct tcacgtatcg agcgcgtcag
    10081 ggtggtacca tcgttggcga tggggtccaa actgcaaaac aatgagaatt tcaacgccgc
    10141 gattgattct tgggctctga atcagaccgc atcatctttg actggaaata tcaacgtgta
    10201 cgacgcagag agcggaagag cgctcatcca agtcgagggg ttcgaagtga gggcggttgg
    10261 tgagccagac gcctcaaagg atcgccttct cttttatgag acagtgtggg gtagagacat
    10321 ttccatcatg ggcttgtcgg accctattcg tgacgagact tccgatgcca tggtgcacaa
    10381 cttgagcgaa gccattgagc gcgtcagcct attctatgtg cgacagctta tgggcgagct
    10441 cagtaccgca gataggcgtc aggcaaactg gtatcacacc cgcatgctcg cggcgtttga
    10501 ctatcatttg gccaaggtcc atgaggaaac gcatcttcac ctgcgcccgg aatggcttgc
    10561 agacgactgg gccgtcatcc aaaccattga tgaggcatac ccagatgctg tcgagttgca
    10621 gatgcttcac gccgttgggc aaaatgtggc agatgtcatc aggggcaaaa agcatttgct
    10681 agaggtcctg cgtgtcgata atctcctcga tcgcctctac acggaagaca agggcatgca
    10741 catggcgaac ctcttcttgg ccaatgcact cgaggaaatt acctttaaat ttcctcggtg
    10801 caagattttg gagattgggg ctggtactgg cgctacagta agtggttttt ttttcctttt
    10861 ttttctttct ttccttcttt tcttttcttt tttttttttt tttttttttt ttttggtttt
    10921 ttttggcaaa ggttgaatac caactcgaca tgacagacct gggccgcact gagtgcaatt
    10981 ggtgaggcat tcgacacgta tacttacaca gatctctcgg ttggcttttt cgagaatgct
    11041 gtcgagagat tttccgcatt tcgtcacagg atggtcttta gagccctcga tattgagaaa
    11101 gacccagcat ctcagagctt tgatctcaat tcgtacgaca tcatcatcgc gaccaatgtc
    11161 ctccatgcca cgaggaacct gggggtcacg ctcggtaatg ttcgagccct cttgaagccc
    11221 ggcggctatc tgctattaaa cgaaaagact ggcccagaga gtcttcgcgc tacctttaac
    11281 tttggtgggc tcgaaggctg gtggcttgcc gaggagaaag agcgtcagct cagcccgctc
    11341 atgtcccccg atggctggga tgcccagctc caaaaggcct cgttctctgg cgttgatcat
    11401 atagtacacg acgttcagga agatcagcag gataagcagc aaaactccat gatcatgagt
    11461 caagccgtgg atgacacgtt ctatgcccgg ctctccccgc tttccgaaat ggccaaccta
    11521 ttgcctatga atgagccgct gctcatcatc ggaggtcaaa caacggctac gttgaagatg
    11581 atcaaagaga ttcaaaagct gctacctcgg cagtggaggc acaaggtgcg tctcattgct
    11641 agtgtcgatc atgtcgaggc cgagggcctg cctgctcact cggatgtgat ttgcctgcaa
    11701 gagctagaca gagggctgtt tacgacagcc atgacgtcaa aatgtctaga tgctctaaag
    11761 acacttttca tcaatacacg aaacctcttg tgggtgacaa atgcccaaaa ctctagctcc
    11821 atgactccca gagctagcat gtttcgaggc atcactcgtg tcttggatgg agaagtcccg
    11881 catattcgaa cccaagttct tggcattgag cccagagaaa ccccttctgc gacggcaaga
    11941 actttgctag aggcgttcct gcgactacga tctgatgatg gtcgtcacgc aggcaatgtg
    12001 gatgaagacg gtgcagatgg cagtagccag caagtgttgt ggttgcatga acccgaggct
    12061 gagcttttgt ccaacggtac catgatggtt cctcgagtca aagcgcgcaa gtccctaaat
    12121 gacacgtatc ttgcttccac tagggctata tctacgacag tggacgctcg ttgtgtctcc
    12181 gtccaagccg tggccgggcc cgccaagatg ctgcttcgac ctgttgaaga ttttgcaggc
    12241 gagcatgcaa tctctaacca gacttcagat tcaaaagtac acattcaagt cgaatcaact
    12301 ctgcacatcc ccgaagcgct ggacggcacc tgtctctacc ttgtctgcgg ctggacacgg
    12361 acggctgaaa catctgtccc ggtaatagcg ctctccgcga acaatgcctc aatggttgcc
    12421 gtcgagtcaa aggcagtagc catgattgat gaggttgatg tgaaacctga aaccctcttg
    12481 cgagttttcc agcacatggc tatgcaagct ctggattctg cagtcaagcg tcatggccag
    12541 ggtcaatcaa cagctctaat ctacggcgcc gacgaagaat tagccaagct gacctcggaa
    12601 agattcgcgg tccgtgaaag caaggtgtac tttgcatcat cacgtacttt tgctcccggc
    12661 gattggctca aggtccagcc tctgctcagc aagtttgccc tgagtcaaat gattcccgct
    12721 gatgttgagg tattcattga ctgccttggc gacacagagt cttttgacgc gtgccgtact
    12781 ctccagtcct gcttatcaac gacacgcacg gtgcagcacc gtctcgacgc ctgtctgctt
    12841 tcgcaaatgt ctcgatgctc ccccgacgct cttgttgatg catattcata tgcaaagacg
    12901 cagtcgaatg ccgagtttag ctggaacggg tatgtcaaaa catttacagc tgcggaactt
    12961 gcgggcaagc tcagtcactc gctcatacac agcgtgtaca tgacaaattg gcaaaagaag
    13021 gactctatac tggtgactgt accgcccctc cagacccgtg ggcttttcaa gagcgacaga
    13081 acctatctca tggttggcgc agcaggcggg cttggcacgt ctatatgccg ttggatggtg
    13141 cgcaatggtg cgcgacatgt ggttgtgacg agccgcaatc ccaaagccga cccagagatg
    13201 ctcaacgagg cggagcgata cggcgccgcc gttcaagttg tgccaatgga cgcttgcagc
    13261 aaagactctg tgcagactgt ggtggacatg attcgtgcca ccatgccgcc tattgctggt
    13321 gtatgcaatg ccgccatggt cttgcgtgac aagctttttc tggacatgaa tgtcgatcat
    13381 atgaaggatg tccttggtcc caagatgcaa ggtacggagc atctggactc gattttcgcc
    13441 caggagcctc tcgacttttt tgtcttgcta agctcgagcg ctgccattct gaataataca
    13501 ggccagtcaa actaccactg cgcaaatctc tacatggaca gcctagtcac gaatcggcgc
    13561 tcgagaggac tcgcagcttc cattatccat gtcggtcatg tctgcgacac gggatacgtt
    13621 gcccgcttgg ttgacgacac caaggtgcag atgagcctag gtaccacgcg agtcatgagt
    13681 gtctctgaga cggatgtgca tcatgccttt gctgaggcgg tccgcggggg gcagccagac
    13741 agccggagcg gctcccacaa catcataatg ggtattgagc caccgacgaa gccactggat
    13801 ctcacgaagc gaaagccagt gtggatttcg gatcctcggc tcggcccatg cctgcctttt
    13861 agcaccctgg agaatcagat gatggcctcg gagcaagcag ccgccgcatc ggcggtagac
    13921 agtctagcgc agcaggtcag cgaagctaca acagatgaag aggctgctgt cgccgcgctc
    13981 aaggggtttg ccaccaagct tgaaggtatc ctgctgttgc cgctaggaag catcggcgag
    14041 gatagtgcgg gcagaccggt gactgacttg ggcatcgact ctctggtggc cgttgagatt
    14101 cggacttggt tcttgaagca gctgcgtgtc gacgttcccg tcatgaagat tctagggggc
    14161 agcacggtcg ggcaactgtc cgcattggca gctaagctcg cccggcagga tgcgaagaaa
    14221 cgggcccaac tcgaagagcc ttccgggaac caacccgttg ctctcccatc accaccacca
    14281 aaggacaagg caggaggact aaacaagaac ggcaaatcac caaagcttcc tgagattgca
    14341 caagtagata cagtggtgga aagaatggaa cctcttgtac ttgaagcgtc agaccgggga
    14401 ggctcttcca ctgccaactt gaccacgagc agcagcgtct ccgagttgga tgacagtctg
    14461 cacgagtcta ctcttcaatc atctgacaac aacggcgagt caactcccag caagtctagc
    14521 aattgcaact ctgattccgg atcggacaat caagcgccca aagagattcc ctcgaatggc
    14581 ttcttcaccc aaccagcagc gactgcgcgt ccaaacgtac tacgagaggc gccaatgtcg
    14641 cccgcccagt cccgcatctg gtttctatca aagcacattg cagagccaga cgcctacaac
    14701 atggtattcc actaccgcgt ccgcgggccc ctcagcatgg tgcgcctccg tcacgccctg
    14761 cagaccgtca ccaaccacca cgagtgtctg tgcatgtgct tctacgccag cgccgacaac
    14821 gggcagccca tgcagggcct gctggcgtcg tctgcgtttc aaatgacgca tgtcccgggc
    14881 ggcgaggaac aagacgtgca gagggagctg cgcaagctaa agacgcgcgt gtggagcgtc
    14941 gagagcgggc agacgctgga gctggtggtt ctcggcccgc ggcctggcac agcggcagca
    15001 gcggaagaag aagaagaaga gttttcgctg ctatttggct atcaccatat cgtcatggac
    15061 gcgattagct tttacatctt cctggccgat ctggacaagg cataccgcat gctgccgctc
    15121 gacaaggctt ctgctggatc gcacctcgat ctggctgcgc atcagcgaca gcaggaacgc
    15181 gcgggcgcgt gggaagagtc gttggaattc tggcgggccg agtttgagac gattccagag
    15241 atgcttccgt cgctatccgt tgcgttgccg actcttcatc gaggcgcagt cggaacgcat
    15301 cgtgtactgc gcgagcttgc ccatgaacaa ggcggcgacg ccgccatcaa gaagatgtgc
    15361 aagcatctcc gcgtcagccc ctttaacctt cacattgccg tgctgcaagt ggtgattgcg
    15421 cgtctggcca gcatcgaaga cgtctgtgta ggcatcgtgg atgccaaccg cagcgactct
    15481 cgtgcctcgc gcatggttgg ctgttttgtc aacatgctcc ccgtccggtc ccgaattcta
    15541 cccaccgcga ccctcgcaga cgtcgcccgc gccgcatcgt ccaaagccct tgccgctttt
    15601 gcgcacggcc aggtgccgct ggacagcatc ctcgacaagg taaaggcgcc gcggcccgcc
    15661 ggcagcacgc cgctgttcca ggtcgccctc aactatcgcc ccgcggccgc gatagcctcc
    15721 aagcaagccc tgggaggcga gtgcgagatg gagcttcttg ccgacgattt caaggatgcg
    15781 gagaatcctt tcgagattag cgtcttggtt agcgagatgt cgggcggccg aatcgcggtc
    15841 gaggtggtct gccagaaatc ccggtacact atgcaggcga ctgaagcgct cctcgacgcg
    15901 tacttgaatg tgctggcggg attcttgtca gactcggccc agagcgtcgg cgactgtgta
    15961 gtccatgacc agagtaaagt tgagcatgct ctggacttgg gcaggggagc gcagaagagc
    16021 ttcgggtggc ctcgtacgct gtctgagcga gtgatgagca tctgccagca gcactcgacc
    16081 aagtctgcaa tcaaagatgg tcgaaacgag ctttcgtatg ctcagttagc ctccagggtt
    16141 aaccgcacag ccagcgccat tcttggcaca ggctgcagtg tcggttcccg catcgcagtc
    16201 ttatgcaacc cctcgattga tgccattgtc gccatgctgg ccattctcca tatcggcggt
    16261 gtatatgttc ctctcgacac cagtctgccc gaggcgcgtc atcagtctct agcatcaaac
    16321 tgcacaccaa gcctaatcat ctcccacgcg gctaccagag agcgtgccca caagctcagc
    16381 gctgcaatca gtgctcctgg ccacgagcca gctcgcgagc tcacactaga cgacttgtcg
    16441 ccaccagaag agactggata catggcgccg ctcaatgccg agccaaacgc ccccgccatc
    16501 ctgctataca ccagtggctc aacgggcacc ccaaagggcg ttttgctcac gcaagccaac
    16561 tttggcaacc acattgcgct caagacggac attctcggtc tgcaacgagg cgagtgcgtc
    16621 ctgcagcaga gctcactcgg ttttgacatg tctctggtgc aagtcttttg cgctctagcc
    16681 aacggcggct gtcttgtcat tgtgcggcaa gacgtaagac gcgatccggt ggagctgaca
    16741 accctcatga ctcagcacaa ggtgtcgctc acaatcgcga cgccatcaga gtacctcgct
    16801 tggctgcagt atggatccga cgcgctcgcg caggccacgt catggaagaa tttgtgcatg
    16861 ggcggcgagc cgatcccgcc gcttctaaaa gatgaactgc gacgccgtct tgagcgcaag
    16921 gacttggtgg tgaccaattg ctatgggccg acggaaacga cggcggcgat atcgtttcag
    16981 tccgtcgccc tcgactcgga acatggccac gagctgccag gcgagagcga gctggcccag
    17041 tacgctgttg gcaaagcact ccccaactac tcgatccgca tccgggactc tgccggcggc
    17101 gcctggctac ctgtcaacca cacgggtgaa atcgtgattg gcggcgctgg cgttgctttg
    17161 gggtatctgg acatgcccga ggagacgcga gcccggtttt tgcagacccc cggcgaggag
    17221 gatggcatga tgttgtatcg cacgggcgac aagggccgtc tgctttccga cggcaccttg
    17281 ctttgctttg ggcgcatcac gggagactac caagtcaagc tccgcggtct tcgcatcgag
    17341 ctcggcgagg tcgaagccgc tctgctccaa gcttcacacg gcctgattca cacggccgtc
    17401 gtatcccgtc gcggagacgt gctcgtcgca cactgcgcgc gctcgcacga gagcagcaga
    17461 gaaactacgg gcggaggaga gcaacaagac gccaccgcca ttcttcgtcg cgtttcggag
    17521 ctgctaccgc agtattctgt tcccgcagcc attgccctgc tcccctcgct gccgaccaat
    17581 gccaatggca aactagaccg caaggccatt gccgctttgc ctctctcccc gcaagacgaa
    17641 gccgccgccg ccacctctcc atccaacaac aacatcaaca acaacacccc ctcgggcggc
    17701 ggcggcgaga agatgacggt ccgtcaaggt gagctgcggc tgctttggga gcgtgttctg
    17761 ccccgcgacg ccgccaccac caccaccaac agtgtgcgca tcacgcccga gtccgacttt
    17821 ttcctgcgcg gcggcaactc gctgctgctg atgaagctgc aggccgccat ccgcgagtcc
    17881 atgggcgtgc gcgtctcgac aaaggcgctg taccaggcga gcacgctcag cggcatggcg
    17941 cggtgcgtcg cagagcagcg gagcgacgac gatgaagcgg aagaggacat tgactgggcg
    18001 gccgaggtgg ctgtgccgcc ctcgatgctg gcacagattg aaaagctgca gcattcctct
    18061 gcttcttcgt cttcttcttc ttcttcttca tcttctgcag ggtcctcctc tacgcagcga
    18121 ccacgcaaga cgtccgggct ggagattctt ttaacaggcg ccacgggctt cctcggcggc
    18181 cagctcctcg agcgccttgt ccagtcacct cgcgtctcta cggtgcactg cgtcgctgta
    18241 cccgtcgacg agcaatcatt actcgagccc ttcttgcagc aacaagccga cggaacaaga
    18301 agaaaagtgc gctgctacat tggcaacctg gccgctcccg ctctcggcct caccgccgcg
    18361 gaccagactg cgctttcgca aaccgccgac gtcattgtcc acgctggctc catgggccac
    18421 tgcctcaaca cgtacgccac gctggcggcg cccaactttg cctcgacccg gcatctctgc
    18481 tccctcgccc tcagccgctc cccgcccatc ccgctcgcct ttgcgtcgtc gaaccgcgtc
    18541 gcgctgctga cgggcagcac cgcgccgcct ccggcttccg ccgccgcgtt tccgccgccg
    18601 ccgggcgcgc agggctttac ggcgagtaag tgggccagcg aggcgttttt ggagaagctc
    18661 gcggcgagca tcatgacctc aaagacaaaa tcgacgacga cgacgacaac gacgaccgtg
    18721 ccgtggaggg tctcgataca taggccctgc gcgctgatta gcgatcgcgc gcccaactct
    18781 gatgccctca acgccattct gcgctactcg acctcgatgc gatgcgtgcc gtcgttgcca
    18841 gagcacaggg ccgagggata cttggacttt gggcaggtgg acaaggtggt cgaggaaatg
    18901 gtgggcgaca tcctcgggct cgcggatgag cgtcagcaag agggacctgc cgtcgtgtat
    18961 aggcaccatt ccgggggcgt caaggtgccg attcacgagt ttcgggagca catggaatct
    19021 gtctatggag gacgctttga gagtgttgag cttgggcaat ggatcgtccg cgccgtcgac
    19081 gccggcatgg atccattgat tagcgcctat ctcgagacct ttttagaggg tgacgcgtcc
    19141 atggtttttc cttatatggg agagcaagca gtttgag
//
