BGC0001049: tenellin biosynthetic gene cluster from Beauveria bassiana
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Location: 1,717 - 20,893 nt. (total: 19,177 nt).
This entry is originally from NCBI GenBank AM409327.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001049
Short description tenellin biosynthetic gene cluster from Beauveria bassiana
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Iterative type I)
Loci
AM409327.1
1717 - 20893
via Knock-out studies, Heterologous expression
Compounds
  • tenellin
Species Beauveria bassiana [taxonomy]
References
Chemical products information
tenellin Evidence:
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C21H23N1O5
Chemical database entries
NPAtlas
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAL69594.1
  • tens1
 1717 - 3369 (+) hypothetical protein
  • Tailoring
  • Knock-out
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  • CAL69595.1
  • tens2
 3777 - 5453 (-) hypothetical protein
  • Tailoring
  • Knock-out
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  • CAL69596.1
  • tens3
 6093 - 7259 (-) hypothetical protein
  • Scaffold biosynthesis
  • Other in vivo study
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  • CAL69597.1
  • tens
 7941 - 20892 (+) PKS-NRPS
  • Scaffold biosynthesis
  • Other in vivo study
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Biosynthesis information

Biosynthetic modules

Name
2
Type
nrps-type1
Genes
tens
Substrates
tyrosine (evidence: Structure-based inference, Heterologous expression)
Integrated Monomers
Domains
condensation (LCL), adenylation
Name
1
Type
pks-modular
Genes
tens
Substrates
Integrated Monomers
Domains
acyltransferase, ketosynthase, acyltransferase, dehydratase, ketoreductase, methyltransferase
Annotation changelog

Entry version: 3

Date
Changes
Submitters
Reviewers
2022-09-15
Fixed gene accessions
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
2022-09-15
Corrected NRP module activity
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
2022-09-15
Updated NRP substrate specificities
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 2

Date
Changes
Submitters
Reviewers
2019-10-16
Migrated from v1.4
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
2019-10-16
Updated compound(s) information (NPAtlas curation)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
2019-10-16
Updated loci information
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 1

Date
Changes
Submitters
Reviewers
2015-06-12
Submitted
  • (ID: 3XTF2R3BHL5LPPSMGJ2QHJQC)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
Detailed domain annotation
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Similar known gene clusters from MIBiG 4.0
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