BGC0001060: dynemicin A biosynthetic gene cluster from Micromonospora chersina
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Location: 1 - 76,048 nt. (total: 76,048 nt).
This entry is originally from NCBI GenBank EF552206.1.

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core biosynthetic genes
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resistance
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Gene details
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001060
Short description dynemicin A biosynthetic gene cluster from Micromonospora chersina
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
EF552206.1
via
Compounds
  • dynemicin A
Species Micromonospora chersina [taxonomy]
References
Chemical products information
dynemicin A Evidence:
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C30H19N1O9
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACB47031.1
 2116 - 3345 (+) hypothetical protein
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    • ACB47032.1
    		 3364 - 4284 (-) NTP pyrophosphohydrolase
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      • ACB47033.1
      		 4478 - 6295 (+) hypothetical protein
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        • ACB47034.1
        		 6369 - 7016 (-) hypothetical protein
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          • ACB47035.1
          		 13044 - 13523 (+) GntT-like protein
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            • ACB47036.1
            		 13423 - 13773 (-) TobX-like protein
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              • ACB47037.1
              		 14054 - 14521 (-) unkown protein
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                • ACB47038.1
                		 14799 - 15254 (+) hypothetical protein
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                  • ACB47039.1
                  		 15598 - 16656 (+) putative tryptophanyl-tRNA synthetase
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                    • ACB47040.1
                    		 16939 - 18657 (+) putative class Ic arginyl-tRNA synthetase
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                      • ACB47041.1
                      		 18716 - 19150 (-) hypothetical protein
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                        • ACB47042.1
                        		 19092 - 20252 (-) putative xanthine/CO dehydrogenases maturation factor
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                          • ACB47043.1
                          		 20194 - 20781 (-) hypothetical protein
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                            • ACB47044.1
                            		 20782 - 22653 (-) CalR2-like protein
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                              • ACB47045.1
                              		 22855 - 23841 (+) DynU15
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                                • ACB47046.1
                                		 23898 - 25796 (+) DynU14
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                                  • ACB47047.1
                                  		 25826 - 26815 (+) DynT3
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                                    • ACB47048.1
                                    		 26849 - 32551 (+) DynE8
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                                      • ACB47049.1
                                      		 32556 - 32990 (+) DynE7
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                                        • ACB47050.1
                                        		 32987 - 33646 (+) DynS6
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                                          • ACB47051.1
                                          		 33652 - 34326 (-) DynU8
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                                            • ACB47052.1
                                            		 34396 - 35319 (+) DynU6
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                                              • ACB47053.1
                                              		 35283 - 37166 (-) DynR2
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                                                • ACB47054.1
                                                		 37274 - 38638 (+) DynR3
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                                                  • ACB47055.1
                                                  		 38660 - 39226 (+) DynU21
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                                                    • ACB47056.1
                                                    		 39223 - 39798 (+) unkown protein
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                                                      • ACB47057.1
                                                      		 39828 - 41045 (-) unkown protein
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                                                        • ACB47058.1
                                                        		 41055 - 41687 (-) unkown protein
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                                                          • ACB47059.1
                                                          		 41709 - 43034 (-) PBS lyase HEAT-like repeat protein
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                                                            • ACB47060.1
                                                            		 43124 - 44674 (+) ketone reductase
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                                                              • ACB47061.1
                                                              		 44713 - 45564 (+) unkown protein
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                                                                • ACB47062.1
                                                                		 45570 - 46421 (+) DynR7
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                                                                  • ACB47063.1
                                                                  		 46468 - 47724 (-) hypothetical protein
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                                                                    • ACB47064.1
                                                                    		 47735 - 48871 (-) FAD-dependent oxidoreductase
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                                                                      • ACB47065.1
                                                                      		 49086 - 49514 (+) putative hydroxylase
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                                                                        • ACB47066.1
                                                                        		 49551 - 50054 (+) putative hydroxylase
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                                                                          • ACB47067.1
                                                                          		 50182 - 51078 (-) conserved hypothetical protein
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                                                                            • ACB47068.1
                                                                            		 51075 - 52604 (-) putative secreted hydrolase
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                                                                              • ACB47069.1
                                                                              		 52523 - 53635 (-) putative methyltransferase
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                                                                                • ACB47070.1
                                                                                		 53691 - 54902 (-) putative cytochrome P450 hydroxylase
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                                                                                  • ACB47071.1
                                                                                  		 54945 - 56147 (-) putative cytochrome P450 hydroxylase
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                                                                                    • ACB47072.1
                                                                                    		 56283 - 56723 (-) hypothetical protein
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                                                                                      • ACB47073.1
                                                                                      		 56720 - 57064 (-) putative transcriptional regulator
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                                                                                        • ACB47074.1
                                                                                        		 57068 - 57439 (-) hypothetical protein
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                                                                                          • ACB47075.1
                                                                                          		 57582 - 58391 (-) putative integral membrane transport protein
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                                                                                            • ACB47076.1
                                                                                            		 58388 - 59389 (-) DynT5
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                                                                                              • ACB47077.1
                                                                                              		 59513 - 59884 (-) hypothetical protein
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                                                                                                • ACB47078.1
                                                                                                		 59911 - 62271 (-) putative carbon monoxide dehydrogenase large subunit
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                                                                                                  • ACB47079.1
                                                                                                  		 62268 - 62762 (-) putative carbon monoxide dehydrogenase small subunit
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                                                                                                    • ACB47080.1
                                                                                                    		 62778 - 63656 (-) putative carbon monoxide dehydrogenase medium subunit
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                                                                                                      • ACB47081.1
                                                                                                      		 63682 - 64731 (-) DynO6
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                                                                                                        • ACB47082.1
                                                                                                        		 64871 - 65890 (-) putative transmembrane transport protein
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                                                                                                          • ACB47083.1
                                                                                                          		 65887 - 66804 (-) putative ABC transporter ATP-binding protein
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                                                                                                            • ACB47084.1
                                                                                                            		 66977 - 67972 (-) putative transmembrane transport protein
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                                                                                                              • ACB47085.1
                                                                                                              		 68128 - 68697 (+) putative 2-component system sensor kinase
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                                                                                                                • ACB47086.1
                                                                                                                		 68795 - 69451 (+) hypothetical protein
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                                                                                                                  • ACB47087.1
                                                                                                                  		 69668 - 70093 (+) hypothetical protein
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                                                                                                                    • ACB47088.1
                                                                                                                    		 70161 - 70586 (+) unkown protein
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                                                                                                                      • ACB47089.1
                                                                                                                      		 71495 - 74911 (-) type I site-specific deoxyribonuclease protein R
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                                                                                                                        Biosynthesis information
                                                                                                                        Annotation changelog

                                                                                                                        Entry version: 4

                                                                                                                        Date
                                                                                                                        Changes
                                                                                                                        Submitters
                                                                                                                        Reviewers
                                                                                                                        2022-10-07
                                                                                                                        Update chemical activity to schema version 2.11
                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                        Entry version: 3

                                                                                                                        Date
                                                                                                                        Changes
                                                                                                                        Submitters
                                                                                                                        Reviewers
                                                                                                                        2022-09-15
                                                                                                                        Updated bioactivity data
                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                        Entry version: 2

                                                                                                                        Date
                                                                                                                        Changes
                                                                                                                        Submitters
                                                                                                                        Reviewers
                                                                                                                        2019-10-16
                                                                                                                        Migrated from v1.4
                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                        2019-10-16
                                                                                                                        Updated compound(s) information (NPAtlas curation)
                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                                                        Entry version: 1

                                                                                                                        Date
                                                                                                                        Changes
                                                                                                                        Submitters
                                                                                                                        Reviewers
                                                                                                                        2015-06-12
                                                                                                                        Submitted
                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                                                        Detailed domain annotation
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