LOCUS       BGC0001064             26219 bp    DNA     linear   BCT 12-NOV-2012
DEFINITION  Cylindrospermum licheniforme UTEX 'B 2014' cylindrocyclophane
            biosynthetic gene cluster, complete sequence.
ACCESSION   BGC0001064
VERSION     BGC0001064
KEYWORDS    .
SOURCE      Cylindrospermum licheniforme UTEX B 2014 (Cylindrospermum
            licheniforme ATCC 29412)
  ORGANISM  Cylindrospermum licheniforme UTEX B 2014
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
            Cylindrospermum.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 14:48:10
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 26219
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..26219
                     /culture_collection="ATCC:29412"
                     /db_xref="taxon:379530"
                     /mol_type="genomic DNA"
                     /organism="Cylindrospermum licheniforme UTEX B 2014"
                     /strain="UTEX 'B 2014'"
     misc_feature    1..26219
                     /note="cylindrocyclophane biosynthetic gene cluster"
     subregion       1..26219
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="PKS"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..26219
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             1069..2886
                     /NRPS_PKS="Domain: CAL_domain (41-477). E-value: 7.1e-132.
                     Score: 432.3. Matches aSDomain:
                     nrpspksdomains_AFV96135.1_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 374;
                     E-value: 1.6e-113)"
                     /gene_kind="biosynthetic-additional"
                     /note="CylA"
                     /product="AMP-dependent synthetase/ligase"
                     /protein_id="AFV96135.1"
                     /sec_met_domain="AMP-binding (E-value: 1.2e-94, bitscore:
                     306.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHLLQQENLSLIEIINYRAQYQPDKKAYIFLQNGEEESASLTYGE
                     LDRRARAIAARLQSWQGERALLLYPSGLEFITAFFGCLYAGVVAMPVYPPKRNQKLSRL
                     LSIVNDAQANLALTTSSILLDISQKWKEETESLTQLNWVPTDTIEADSQDFVPTLVTPE
                     SLAFLQYTSGSTGTPKGVMVTHGNLIHNSECIKQAFELTSDSVSVSWLPTFHDMGLIDG
                     VLQPLYTGFTGYLMPPVAFLMKPACWLQAITRYKATHCGGPNFAYDLCVSKVTSEQLKT
                     LDLSSWYTAYSGSEPVRNETLNLFVEKFRDCGFKENFFYPCYGMAEATLFISGGFKQSP
                     PIVKCLQAQTLKENIIVDVTHPTPSSQEASKVLVGCGHSWLDYKIVIADPESFELCADG
                     RVGEIWVSSASVTKGYWNRPQQTQETFKAYLKDGLGPFLRTGDLGFLHDGELYVTGRLK
                     DIIIIRGQNHYPQDIELTVQKSYSALRLNCGAAFTIEVKGKEQLIIVQEVERTYLKKLD
                     VNHVLEIITQAVATEHGLQVYATVLVKTGSIPKTSSGKIQRHACRTKFLNASLDVVEDW
                     SENPQYKSGFIRLQDEVESVFNTFAKKRE"
     aSDomain        1192..2499
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96135.1_CAL_domain.1"
                     /evalue="7.10E-132"
                     /label="AFV96135.1_CAL_domain.1"
                     /locus_tag="AFV96135.1"
                     /protein_end="477"
                     /protein_start="41"
                     /score="432.3"
                     /tool="antismash"
                     /translation="TYGELDRRARAIAARLQSWQGERALLLYPSGLEFITAFFGCLYAG
                     VVAMPVYPPKRNQKLSRLLSIVNDAQANLALTTSSILLDISQKWKEETESLTQLNWVPT
                     DTIEADSQDFVPTLVTPESLAFLQYTSGSTGTPKGVMVTHGNLIHNSECIKQAFELTSD
                     SVSVSWLPTFHDMGLIDGVLQPLYTGFTGYLMPPVAFLMKPACWLQAITRYKATHCGGP
                     NFAYDLCVSKVTSEQLKTLDLSSWYTAYSGSEPVRNETLNLFVEKFRDCGFKENFFYPC
                     YGMAEATLFISGGFKQSPPIVKCLQAQTLKENIIVDVTHPTPSSQEASKVLVGCGHSWL
                     DYKIVIADPESFELCADGRVGEIWVSSASVTKGYWNRPQQTQETFKAYLKDGLGPFLRT
                     GDLGFLHDGELYVTGRLKDIIIIRGQNHYPQDIELTV"
     CDS_motif       1564..1623
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96135.1_0001"
                     /evalue="6.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="AFV96135.1"
                     /protein_end="185"
                     /protein_start="165"
                     /score="31.0"
                     /tool="antismash"
                     /translation="AFLQYTSGSTGTPKGVMVTH"
     CDS_motif       2260..2346
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96135.1_0002"
                     /evalue="4.00E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="AFV96135.1"
                     /protein_end="426"
                     /protein_start="397"
                     /score="35.2"
                     /tool="antismash"
                     /translation="DGRVGEIWVSSASVTKGYWNRPQQTQETF"
     CDS_motif       2428..2490
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96135.1_0003"
                     /evalue="8.70E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="AFV96135.1"
                     /protein_end="474"
                     /protein_start="453"
                     /score="18.3"
                     /tool="antismash"
                     /translation="TGRLKDIIIIRGQNHYPQDIE"
     CDS             3419..3745
                     /NRPS_PKS="Domain: ACP (32-102). E-value: 1.5e-18. Score:
                     58.8. Matches aSDomain: nrpspksdomains_AFV96136.1_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047:phosphopantetheine-binding domain-containing
                     protein (Score: 82.1; E-value: 4.2e-25)"
                     /gene_kind="biosynthetic-additional"
                     /note="CylB"
                     /product="acyl carrier protein"
                     /protein_id="AFV96136.1"
                     /sec_met_domain="PP-binding (E-value: 3.1e-15, bitscore:
                     46.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIVNSQINSISVDAENNHARAKKLPTKVEIQTWLVNYLVEQLDL
                     NPARVDVSIPFERYGIDSAAAIVLVGDLKDWLEIDLEPTLIYDYPSIEELARHLNDSIK
                     AEYS"
     aSDomain        3515..3724
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96136.1_ACP.1"
                     /evalue="1.50E-18"
                     /label="AFV96136.1_ACP.1"
                     /locus_tag="AFV96136.1"
                     /protein_end="102"
                     /protein_start="32"
                     /score="58.8"
                     /tool="antismash"
                     /translation="TWLVNYLVEQLDLNPARVDVSIPFERYGIDSAAAIVLVGDLKDWL
                     EIDLEPTLIYDYPSIEELARHLNDS"
     CDS             4003..5418
                     /codon_start=1
                     /note="CylC"
                     /product="hypothetical protein"
                     /protein_id="AFV96137.1"
                     /transl_table=11
                     /translation="MTSVNVKLKDEESSTLIENNKKKHLKVTEITYKNNTESNYTEKIE
                     ELDKSFNYSDNSNHYWSHPELSIFYGTPLYAEASHSQKIALNHLYWVTQYSQIAASEAN
                     TILYNDVTNGVFFAVGGYEMLCKELDLESNQEKSHIHAFHTISYKTKKALLGKAALTTP
                     VELNQSQALENNSQENAASKALQKLLGYKPLSSTPLALEDAALRLLKNIRLKSKADCYS
                     PYLHELEKKDLFLPGPRTGILRVFPRYLLRLFTLSWGSSSFLASQYYCFRYIANMLLKT
                     AEYEYTRHYRDLEKTGDFIPNPTEVSRYHLLDESYHTTMSKLIAQDVYKDFAKPTAYER
                     YMGNLSVKVTQSRLLGGLSGGLPAIFQDDSWFTLSYYKLLRSPIFNMSHEETLHWLEKC
                     LCHEHEGFHVNLKYHHRLLTDLRYFFGEFDYMWPVNREMSLMAEGGSLEKAIQRNIESF
                     RDFSKSFTKGAIK"
     CDS             5656..9342
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (5-429). E-value:
                     6.7e-189. Score: 620.0. Matches aSDomain:
                     nrpspksdomains_AFV96138.1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (534-831). E-value: 2.5e-112.
                     Score: 366.9. Matches aSDomain:
                     nrpspksdomains_AFV96138.1_PKS_AT.1"
                     /NRPS_PKS="Domain: ACP_beta (997-1064). E-value: 4.4e-30.
                     Score: 95.2. Matches aSDomain:
                     nrpspksdomains_AFV96138.1_ACP_beta.1"
                     /NRPS_PKS="Domain: PP-binding (1166-1217). E-value:
                     5.6e-07. Score: 21.9. Matches aSDomain:
                     nrpspksdomains_AFV96138.1_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 263.7; E-value: 6.2e-80)"
                     /gene_kind="biosynthetic"
                     /note="CylD"
                     /product="polyketide synthase"
                     /protein_id="AFV96138.1"
                     /sec_met_domain="hyb_KS (E-value: 3.1e-202, bitscore:
                     661.7, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5.4e-113, bitscore:
                     366.9, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-16, bitscore:
                     50.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMEAIAIIGIGVRSPGAKNPESFWHLLREGVDAITEVPLERWNV
                     DEFYDPKPATAGKMITRCGGFVDEVDSFDAGFFGISPREAECMDPQQRLVLEVAWEALE
                     NAGIAPDKLNGSQTGVFMGIGNYDYGRLQSWHFSRLNAYDGTGTSLGVAANRLSYVLNL
                     HGPSLVMETSCSSSLVAVHYASQSLHSKESDLCLVGGVSLILSPESHIIFSQARMMAPD
                     GRCKTFDASADGYVRGEGCGVIVLKRLSDALRDGDNILATIRGSAVNQDGRSNGLTAPN
                     GPTQQAVIRKALENAGVTADQISYVEAHGTGTSLGDPIEFNSLKTVLMKGRQPTQTCYI
                     GSVKTNIGHLEPAAGIVGLIKVVLSLQNKQIPPHLHFKQLNPYIKINNTPLTIPTALQE
                     WNVDQGSRLAGVSAFGFGGTNAHVILEEAPESVAVVKNIERPQQLLALSAKSGKALQEL
                     VRSYEAYLESHPERSLEDVCYTANTGRSHFPHRLAIIASHKQELADKLSKISAEQEVNQ
                     VFFSQNSGDSISPKIAFLFTGQGSQYINMGRQLYETQTVFRQTIDKCEQILQSYSEKSL
                     LDVLYPEDNQQLNNSLIDQTAYTQTALFAIEYALAQLWQSWGIKPDVVMGHSVGEYVAA
                     TVAGVFSLEDGLKLIAHRGRLMQSLPEGGEMLAVMATEEKINQLIAPYTEKVAIAAINE
                     PFSIVISGAGEVIRTLRDSLNAEGIKTHQLQVSHAFHSPLVESILAEFEAIANTITYNQ
                     PQIPLISNVSGTKAHENIATASYWVNHARQPVHFAQSIKVLHQEGYEIFLEIGPKPILL
                     GMGRECLMGNKKLWLPSLHPSRPDWLQMLQTLGQLYAQGVKVDWAGFYKDYSYQKVALP
                     TYPWQRKRYWITNIQEGKNQDKISLISQGETTRTNGNIQSQERQMNENKILQQTKLTLS
                     NPELLSFPKAPLKTEETPTRQLAQLTVPSIQVEPAESTQPQVESGNIAQTRSISALNNS
                     NGNVNQIKQTLKESLASALYTDISEIEEDKKFIDLGLDSIVGVEWLTTINQTYNLNIKA
                     TKLYDYPTLLDLAKYITQEISSIGGSRLAPNNQDSPKESPQNQDSSGDSQEDLRHKLRS
                     ILNKVANKELTVQEANQIIQEIKQKAASSSKFQSNGTNNNRIFQIIKKSIYEVEPKLER
                     APLKTTDSLRQLGIDSVNRAEIMTIVMEELDLHIPLIELAGAQNIGELADLFATKLEAH
                     HGI"
     aSDomain        5671..6942
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96138.1_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="6.70E-189"
                     /label="AFV96138.1_PKS_KS.1"
                     /locus_tag="AFV96138.1"
                     /protein_end="429"
                     /protein_start="5"
                     /score="620.0"
                     /tool="antismash"
                     /translation="IAIIGIGVRSPGAKNPESFWHLLREGVDAITEVPLERWNVDEFYD
                     PKPATAGKMITRCGGFVDEVDSFDAGFFGISPREAECMDPQQRLVLEVAWEALENAGIA
                     PDKLNGSQTGVFMGIGNYDYGRLQSWHFSRLNAYDGTGTSLGVAANRLSYVLNLHGPSL
                     VMETSCSSSLVAVHYASQSLHSKESDLCLVGGVSLILSPESHIIFSQARMMAPDGRCKT
                     FDASADGYVRGEGCGVIVLKRLSDALRDGDNILATIRGSAVNQDGRSNGLTAPNGPTQQ
                     AVIRKALENAGVTADQISYVEAHGTGTSLGDPIEFNSLKTVLMKGRQPTQTCYIGSVKT
                     NIGHLEPAAGIVGLIKVVLSLQNKQIPPHLHFKQLNPYIKINNTPLTIPTALQEWNVDQ
                     GSRLAGVSAFGFGGTNAHVILEEAP"
     aSModule        5671..8847
                     /complete
                     /domains="nrpspksdomains_AFV96138.1_PKS_KS.1"
                     /domains="nrpspksdomains_AFV96138.1_PKS_AT.1"
                     /domains="nrpspksdomains_AFV96138.1_ACP_beta.1"
                     /locus_tags="AFV96138.1"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       6148..6195
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96138.1_0001"
                     /evalue="7.60E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="AFV96138.1"
                     /protein_end="180"
                     /protein_start="164"
                     /score="15.1"
                     /tool="antismash"
                     /translation="GPSLVMETSCSSSLVA"
     CDS_motif       6337..6375
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96138.1_0002"
                     /evalue="3.20E-05"
                     /label="PKSI-KS_m4"
                     /locus_tag="AFV96138.1"
                     /protein_end="240"
                     /protein_start="227"
                     /score="16.7"
                     /tool="antismash"
                     /translation="FDASADGYVRGEG"
     CDS_motif       6568..6615
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96138.1_0003"
                     /evalue="7.20E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="AFV96138.1"
                     /protein_end="320"
                     /protein_start="304"
                     /score="14.6"
                     /tool="antismash"
                     /translation="YVEAHGTGTSLGDPIE"
     CDS_motif       6676..6720
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96138.1_0004"
                     /evalue="7.40E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="AFV96138.1"
                     /protein_end="355"
                     /protein_start="340"
                     /score="12.0"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEPAAG"
     aSDomain        7258..8148
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96138.1_PKS_AT.1"
                     /evalue="2.50E-112"
                     /label="AFV96138.1_PKS_AT.1"
                     /locus_tag="AFV96138.1"
                     /protein_end="831"
                     /protein_start="534"
                     /score="366.9"
                     /tool="antismash"
                     /translation="LFTGQGSQYINMGRQLYETQTVFRQTIDKCEQILQSYSEKSLLDV
                     LYPEDNQQLNNSLIDQTAYTQTALFAIEYALAQLWQSWGIKPDVVMGHSVGEYVAATVA
                     GVFSLEDGLKLIAHRGRLMQSLPEGGEMLAVMATEEKINQLIAPYTEKVAIAAINEPFS
                     IVISGAGEVIRTLRDSLNAEGIKTHQLQVSHAFHSPLVESILAEFEAIANTITYNQPQI
                     PLISNVSGTKAHENIATASYWVNHARQPVHFAQSIKVLHQEGYEIFLEIGPKPILLGMG
                     RECLMGNKKLWLPSLH"
     CDS_motif       7261..7308
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96138.1_0005"
                     /evalue="7.70E-07"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="AFV96138.1"
                     /protein_end="551"
                     /protein_start="535"
                     /score="21.3"
                     /tool="antismash"
                     /translation="FTGQGSQYINMGRQLY"
     CDS_motif       7447..7503
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96138.1_0006"
                     /evalue="3.30E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="AFV96138.1"
                     /protein_end="616"
                     /protein_start="597"
                     /score="13.8"
                     /tool="antismash"
                     /translation="YTQTALFAIEYALAQLWQS"
     CDS_motif       7507..7629
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96138.1_0007"
                     /evalue="2.00E-29"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="AFV96138.1"
                     /protein_end="658"
                     /protein_start="617"
                     /score="94.1"
                     /tool="antismash"
                     /translation="GIKPDVVMGHSVGEYVAATVAGVFSLEDGLKLIAHRGRLMQ"
     CDS_motif       7915..7947
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96138.1_0008"
                     /evalue="3.20E-03"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="AFV96138.1"
                     /protein_end="764"
                     /protein_start="753"
                     /score="10.3"
                     /tool="antismash"
                     /translation="PQIPLISNVSG"
     CDS_motif       7981..8016
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96138.1_0009"
                     /evalue="3.60E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="AFV96138.1"
                     /protein_end="787"
                     /protein_start="775"
                     /score="14.0"
                     /tool="antismash"
                     /translation="YWVNHARQPVHF"
     aSDomain        8647..8847
                     /aSDomain="ACP_beta"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96138.1_ACP_beta.1"
                     /evalue="4.40E-30"
                     /label="AFV96138.1_ACP_beta.1"
                     /locus_tag="AFV96138.1"
                     /protein_end="1064"
                     /protein_start="997"
                     /score="95.2"
                     /tool="antismash"
                     /translation="QTLKESLASALYTDISEIEEDKKFIDLGLDSIVGVEWLTTINQTY
                     NLNIKATKLYDYPTLLDLAKYI"
     aSDomain        9154..9306
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96138.1_PP-binding.1"
                     /evalue="5.60E-07"
                     /label="AFV96138.1_PP-binding.1"
                     /locus_tag="AFV96138.1"
                     /protein_end="1217"
                     /protein_start="1166"
                     /score="21.9"
                     /tool="antismash"
                     /translation="APLKTTDSLRQLGIDSVNRAEIMTIVMEELDLHIPLIELAGAQNI
                     GELADL"
     CDS             9332..10573
                     /NRPS_PKS="Domain: PKS_KS(Enediyne-KS) (86-411). E-value:
                     3.1e-48. Score: 156.6. Matches aSDomain:
                     nrpspksdomains_AFV96139.1_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: t2pks2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 337; E-value:
                     2.9e-102)"
                     /gene_kind="biosynthetic"
                     /note="CylE"
                     /product="beta-ketoacyl synthase"
                     /protein_id="AFV96139.1"
                     /sec_met_domain="t2pks2 (E-value: 2.6e-179, bitscore:
                     586.0, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGYSFAPIRIEITGMGIVTPIGQGVAAFRDALLAGKTQFGYLKRS
                     GREGSRSFIGAELPDISAKSLLPEHSGLLRTASWSSQIASVAVSEAWEDAQLSSGKVNP
                     ERIGIVVGGSNFQERDKQQIWQRYQSNPEFIRPTYGVTLWDTDVMSLLSQCFQIQGEGY
                     SVGAASASGAVAIIHAARQILMGITDVSVAVGSLFDISQWECQGFTNLGAMGSARFADT
                     PDLACRPFDRDHDGFIYGEGCGVLVLERTDHAQQRGVRSHGELIGWGLGLDGKRTPEPS
                     QKGEEQAMNAALAIANLKPEQIDYVNTHGTGSPLGDKTEVAALKSVGLSHCLLNSTKSL
                     TGHCLTAAGVVEVIATLLQMKFGFCHPTHNLVNPIDTTLNWVKETSIKAEIQYAISNSF
                     AFGGINTALLIKKE"
     aSDomain        9590..10564
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96139.1_PKS_KS.1"
                     /domain_subtypes="Enediyne-KS"
                     /evalue="3.10E-48"
                     /label="AFV96139.1_PKS_KS.1"
                     /locus_tag="AFV96139.1"
                     /protein_end="411"
                     /protein_start="86"
                     /score="156.6"
                     /tool="antismash"
                     /translation="AVSEAWEDAQLSSGKVNPERIGIVVGGSNFQERDKQQIWQRYQSN
                     PEFIRPTYGVTLWDTDVMSLLSQCFQIQGEGYSVGAASASGAVAIIHAARQILMGITDV
                     SVAVGSLFDISQWECQGFTNLGAMGSARFADTPDLACRPFDRDHDGFIYGEGCGVLVLE
                     RTDHAQQRGVRSHGELIGWGLGLDGKRTPEPSQKGEEQAMNAALAIANLKPEQIDYVNT
                     HGTGSPLGDKTEVAALKSVGLSHCLLNSTKSLTGHCLTAAGVVEVIATLLQMKFGFCHP
                     THNLVNPIDTTLNWVKETSIKAEIQYAISNSFAFGGINTALLIK"
     CDS_motif       10244..10291
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96139.1_0001"
                     /evalue="5.10E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="AFV96139.1"
                     /protein_end="320"
                     /protein_start="304"
                     /score="9.7"
                     /tool="antismash"
                     /translation="YVNTHGTGSPLGDKTE"
     CDS             10578..11837
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:hydroxymethylglutaryl-CoA synthase (Score: 484.1;
                     E-value: 4.8e-147)"
                     /gene_kind="biosynthetic"
                     /note="CylF"
                     /product="HMG-CoA synthase-like enzyme"
                     /protein_id="AFV96140.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 2.9e-09,
                     bitscore: 26.4, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQVGIEALNIYGGASQLDVRMLAQARHLDTSRFDNLMMKEKAVS
                     LPYEDPVSYAVNAAKPIIDRLSDSDKQRVEMVITCSESGIDFGKSMSTYIQDYLGLSRN
                     CRMFELKQACYSGTAGLQMAINFILSQTSPGAKALVIATDISRFTLAEGGEALSEDWSF
                     AEPSSGAGAAAILVSDVPYIFQVDVGCNGYYGYEVMDTCRPKPDSEAGDADLSLLSYLD
                     CCENAYLHYQKRVEGVDYQKSFDYLSFHTPFGGMVKGAHRNMMRKLKKAKPEEIEADFQ
                     RRVMPGLVYCQQVGNIMGATVFLALASTIDNGDFSQPRRIGIFSYGSGCSSEFYSGVVT
                     PEGKEIQAQQRISSQLATRYSLNIEEYEQLLHYSRVVAFGTRNVTLDYKIFPGVWKQIE
                     GKGRLVLKKIKEFHREYEWV"
     CDS             11840..12604
                     /NRPS_PKS="Domain: ECH (8-246). E-value: 1.3e-49. Score:
                     160.5. Matches aSDomain: nrpspksdomains_AFV96141.1_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 182.2; E-value:
                     1.6e-55)"
                     /gene_kind="biosynthetic-additional"
                     /note="CylG"
                     /product="enoyl-CoA hydratase/isomerase"
                     /protein_id="AFV96141.1"
                     /transl_table=11
                     /translation="MDYQTLKINHQSAVQRIQIYRPEANNSINSQLIQELLSALQAAEA
                     EEAVKVVILEGLPDVFCTGMDFQEIADGKQVDPKMSSHGYYNILKQMSQCSIVIVSLVR
                     GKVQAGGVGLVAASDIVIADETVTFVLSELLFGLLPACVLPFLIRRIGFQKAYRLALTT
                     QEISASEAYNLGLIDEYGSNTNKLISQYVKRLKYLPSSGVRELKNYINQLWIIQAETQD
                     LAVNKISSLLDDPTVQEKIKRFKNEGVFPWQA"
     aSDomain        11864..12577
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96141.1_ECH.1"
                     /evalue="1.30E-49"
                     /label="AFV96141.1_ECH.1"
                     /locus_tag="AFV96141.1"
                     /protein_end="246"
                     /protein_start="8"
                     /score="160.5"
                     /tool="antismash"
                     /translation="NHQSAVQRIQIYRPEANNSINSQLIQELLSALQAAEAEEAVKVVI
                     LEGLPDVFCTGMDFQEIADGKQVDPKMSSHGYYNILKQMSQCSIVIVSLVRGKVQAGGV
                     GLVAASDIVIADETVTFVLSELLFGLLPACVLPFLIRRIGFQKAYRLALTTQEISASEA
                     YNLGLIDEYGSNTNKLISQYVKRLKYLPSSGVRELKNYINQLWIIQAETQDLAVNKISS
                     LLDDPTVQEKIKRFKN"
     CDS             12592..19266
                     /NRPS_PKS="Domain: ECH (20-258). E-value: 9.6e-55. Score:
                     177.4. Matches aSDomain: nrpspksdomains_AFV96142.1_ECH.1"
                     /NRPS_PKS="Domain: PKS_ER (315-634). E-value: 8.2e-102.
                     Score: 332.3. Matches aSDomain:
                     nrpspksdomains_AFV96142.1_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (878-1304). E-value:
                     2.1e-172. Score: 565.7. Matches aSDomain:
                     nrpspksdomains_AFV96142.1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1415-1710). E-value: 4.4e-113.
                     Score: 369.4. Matches aSDomain:
                     nrpspksdomains_AFV96142.1_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_PP (1863-1926). E-value: 1.9e-09.
                     Score: 29.6. Matches aSDomain:
                     nrpspksdomains_AFV96142.1_PKS_PP.1"
                     /NRPS_PKS="Domain: Thioesterase (1993-2217). E-value:
                     2.6e-44. Score: 144.2. Matches aSDomain:
                     nrpspksdomains_AFV96142.1_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     tra_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 273.6; E-value: 3.7e-83)"
                     /gene_kind="biosynthetic"
                     /note="CylH"
                     /product="polyketide synthase"
                     /protein_id="AFV96142.1"
                     /sec_met_domain="ADH_N (E-value: 1.7e-10, bitscore: 30.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.9e-18, bitscore:
                     55.4, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 1.4e-178, bitscore:
                     583.7, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 9.5e-114, bitscore:
                     369.4, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3e-09, bitscore:
                     27.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASLNFNLDSAKGNSEVVQLVELGNGVVKITMKDEENHNTFSSEI
                     IDGLYKCFGAVAQNKSYKVVILTGYGNYFCSGGTKEELIKIYKGELQFNELDFFRILLD
                     CEIPVIAAMQGHGIGGGFVFGLYADLVVLSQESIYTTNFMKYGFTPGLGSTFIVPTKLG
                     SVLGQEMMYTAQNYRGKELFKKGIPFPVVPRKEVLNHALMLGYKIAEKPRLSLVTLKEH
                     LTSEIKKRLPEVLEKELKMHDITFHQLEVANRIETIYGDTNISSQPHNLSQELVNESAD
                     VQNQVPLLSSQKNRQEIIENSITLKQVQLKISSYGLLNNLTLAPLQRRVLGCAEVEVQI
                     KAVAVNFRDVINALGMLKEYNEQKFGITSVENLIFGFEGVGTIVAVGEEVTQWQVGDEV
                     MVIGIHDAFSSFIVCSPNNLVAKPSNLSMVSAATIPIPFFTAAHGLYNLAKIQPGERVL
                     IHAAAGGTGQASVQLAQLMGAEVFATASPGKMAFLQRQGIKHIMNSRTTEFADQVMELT
                     QGCGVDVIFNSLTHGEYIQKNIDILALGGRYVEIGKLNIWSHEQVAQKRADVKYFPFDL
                     GDEFAKDSQLFSRIWGKLAQHFERDYLKPLHYKEFPLEDVVESFRYIQHSKHIGRVVVT
                     MPESSYWGEESNGDRLSNQNKLINQEDVLHQLQSGAVSLEEAEKLLLGFTEEVEETLEK
                     KPIENGHNKLINQEDVLHQLQSGAVSLEEAEKLLLGFTEEVEETLEKKPIENGHNKLIN
                     QEDVLHQLQSGAVSLEEAEKLLLGFTEEVEETLEKKPIENGHNKLITKDDSESILSLQS
                     AGAISLENIENGHNKLITKDDSESILSLQSAGAISLENAEKLLLEKTVESETKINTVIS
                     KLVKNTDIAIIGISCRYPGAKNWQEFWKNLKNGIDSVTEVPPGRWQEKEWYHPDPEHVG
                     TSYSKCAGFLDEIDKFDPLFFQISPVEAQFIEPQQRIFLEEAYHAIEDAGYATDSLKGK
                     QCGVFVGAGTNGDYNKLLSIAGLDTHRLALTGNLLSMIPARIAYFLDLRGPVVAIDTAC
                     SSSLVAVHQACESIQRGESELAIAGGIAIMATADFQVLSSQFQMLSAAGRCKTFDASAS
                     GTVWSEGCGVVLLKSYEQAIRDNDHIYAVIKGTGVNYDGNTNGISAPSGQSQTRLEEGV
                     YQKFGINPETISYVEAHGTATPLGDPIEVEGLTAAFSKWTTKKQFCAIGSVKTNIGHAA
                     TSAGISGLIKTILCLKNQKLVPSLHFNQPNPHIDFENSPFYVNTEFKDWQVTDRNPRRA
                     TVSSFGFSGTNAHLVIEEAPLQVNSQNLRFPGDEFSQRSHHLLTLSAKCEKGLQELVQD
                     YQEFLETNSTAALSDVCFSANTGRSHFDYRLALVAESTENLLQQLKAFATGEETTKLLR
                     GQATSKERPKIAFLFTGQGSQYVDMGRELYSTQPVFRKTLEECDRILRLYLDKPLLNIL
                     YPASGDTSVIDETAYTQPALFAIEYALVQLWKSWGIQPDVVMGHSAGEYVAACVAGVFS
                     LEDALKLIAHRGKLMQALPANGKMVSVMADEATVTAAISSCRWEVAIAAYNGPESIVIS
                     DQQDKVDVVKALLEDKGIKTKELNVFHAFHSPLMEPMLAEYETIATQVSYKTPQIPLIS
                     NVTGKRVDESIASAKYWVRHVKEPVKFAQSMETLNAQGNFIFLEIGPKPILLGMGRQCL
                     PSDVGVWLPSLRQRVKDWQQILNSLGQLYVQGIEVDWSEFDRDYARCKVTLPTYPFQRQ
                     RYWVETAKDGVGQQKVQSLKQENTSSPIYHLLCKGETELVSSELEKLGVLSQDEIKLLP
                     KLLKLLVEQHQQQFKIESNAHQNESAKTDEKIASPPASEPSNKGDEILAADSETRQQLL
                     RTYIGQILAKVVGISPAALNWQKRLSELGFDSLMAADLRKTIDSNLKVAVPVEYLAELN
                     IEQFLTQILYLIEQKFPKEHLQKANSTIDEQKSSINPVKKVVDEAQKWFKVSPRNSQPQ
                     FRLFCFPHAGASSYIFNSWPEKFASKIEVCPIQLPGRGNRVKEPAFTKIKPLVQTFAPL
                     LKPYLDVPFAFFGHSMGALLSFELARELRRQNYPNPDYLFVGGYRAPHIPDLNLPIYKL
                     PEPKFIQAISGYGGIPENMLQDPFFLQTFLPTFRADFELLDTYFHTKEEPLESPIYIFG
                     GLEDHTVGIKELSGWEEQTKANFKLKMFNGDHFFLRGVEDEIINIIEETIFCTIN"
     aSDomain        12652..13365
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96142.1_ECH.1"
                     /evalue="9.60E-55"
                     /label="AFV96142.1_ECH.1"
                     /locus_tag="AFV96142.1"
                     /protein_end="258"
                     /protein_start="20"
                     /score="177.4"
                     /tool="antismash"
                     /translation="VELGNGVVKITMKDEENHNTFSSEIIDGLYKCFGAVAQNKSYKVV
                     ILTGYGNYFCSGGTKEELIKIYKGELQFNELDFFRILLDCEIPVIAAMQGHGIGGGFVF
                     GLYADLVVLSQESIYTTNFMKYGFTPGLGSTFIVPTKLGSVLGQEMMYTAQNYRGKELF
                     KKGIPFPVVPRKEVLNHALMLGYKIAEKPRLSLVTLKEHLTSEIKKRLPEVLEKELKMH
                     DITFHQLEVANRIETI"
     aSModule        12652..14493
                     /domains="nrpspksdomains_AFV96142.1_ECH.1"
                     /domains="nrpspksdomains_AFV96142.1_PKS_ER.1"
                     /incomplete
                     /locus_tags="AFV96142.1"
                     /tool="antismash"
                     /type="pks"
     aSDomain        13537..14493
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96142.1_PKS_ER.1"
                     /evalue="8.20E-102"
                     /label="AFV96142.1_PKS_ER.1"
                     /locus_tag="AFV96142.1"
                     /protein_end="634"
                     /protein_start="315"
                     /score="332.3"
                     /tool="antismash"
                     /translation="GLLNNLTLAPLQRRVLGCAEVEVQIKAVAVNFRDVINALGMLKEY
                     NEQKFGITSVENLIFGFEGVGTIVAVGEEVTQWQVGDEVMVIGIHDAFSSFIVCSPNNL
                     VAKPSNLSMVSAATIPIPFFTAAHGLYNLAKIQPGERVLIHAAAGGTGQASVQLAQLMG
                     AEVFATASPGKMAFLQRQGIKHIMNSRTTEFADQVMELTQGCGVDVIFNSLTHGEYIQK
                     NIDILALGGRYVEIGKLNIWSHEQVAQKRADVKYFPFDLGDEFAKDSQLFSRIWGKLAQ
                     HFERDYLKPLHYKEFPLEDVVESFRYIQHSKHIGRVVV"
     CDS_motif       13882..13926
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0001"
                     /evalue="2.50E-03"
                     /label="PKSI-ER_m4"
                     /locus_tag="AFV96142.1"
                     /protein_end="445"
                     /protein_start="430"
                     /score="11.4"
                     /tool="antismash"
                     /translation="AATIPIPFFTAAHGL"
     CDS_motif       13951..14013
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0002"
                     /evalue="1.30E-09"
                     /label="PKSI-ER_m5"
                     /locus_tag="AFV96142.1"
                     /protein_end="474"
                     /protein_start="453"
                     /score="30.3"
                     /tool="antismash"
                     /translation="GERVLIHAAAGGTGQASVQLA"
     CDS_motif       14023..14070
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0003"
                     /evalue="3.60E-03"
                     /label="PKSI-ER_m6"
                     /locus_tag="AFV96142.1"
                     /protein_end="493"
                     /protein_start="477"
                     /score="10.3"
                     /tool="antismash"
                     /translation="GAEVFATASPGKMAFL"
     CDS_motif       14140..14178
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0004"
                     /evalue="3.90E-03"
                     /label="PKSI-ER_m7"
                     /locus_tag="AFV96142.1"
                     /protein_end="529"
                     /protein_start="516"
                     /score="10.0"
                     /tool="antismash"
                     /translation="TQGCGVDVIFNSL"
     CDS_motif       14449..14493
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0005"
                     /evalue="1.50E-04"
                     /label="PKSI-ER_m9"
                     /locus_tag="AFV96142.1"
                     /protein_end="634"
                     /protein_start="619"
                     /score="14.8"
                     /tool="antismash"
                     /translation="FRYIQHSKHIGRVVV"
     aSDomain        15226..16503
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96142.1_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="2.10E-172"
                     /label="AFV96142.1_PKS_KS.1"
                     /locus_tag="AFV96142.1"
                     /protein_end="1304"
                     /protein_start="878"
                     /score="565.7"
                     /tool="antismash"
                     /translation="IAIIGISCRYPGAKNWQEFWKNLKNGIDSVTEVPPGRWQEKEWYH
                     PDPEHVGTSYSKCAGFLDEIDKFDPLFFQISPVEAQFIEPQQRIFLEEAYHAIEDAGYA
                     TDSLKGKQCGVFVGAGTNGDYNKLLSIAGLDTHRLALTGNLLSMIPARIAYFLDLRGPV
                     VAIDTACSSSLVAVHQACESIQRGESELAIAGGIAIMATADFQVLSSQFQMLSAAGRCK
                     TFDASASGTVWSEGCGVVLLKSYEQAIRDNDHIYAVIKGTGVNYDGNTNGISAPSGQSQ
                     TRLEEGVYQKFGINPETISYVEAHGTATPLGDPIEVEGLTAAFSKWTTKKQFCAIGSVK
                     TNIGHAATSAGISGLIKTILCLKNQKLVPSLHFNQPNPHIDFENSPFYVNTEFKDWQVT
                     DRNPRRATVSSFGFSGTNAHLVIEEAP"
     aSModule        15226..19242
                     /complete
                     /domains="nrpspksdomains_AFV96142.1_PKS_KS.1"
                     /domains="nrpspksdomains_AFV96142.1_PKS_AT.1"
                     /domains="nrpspksdomains_AFV96142.1_PKS_PP.1"
                     /domains="nrpspksdomains_AFV96142.1_Thioesterase.1"
                     /final_module
                     /locus_tags="AFV96142.1"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       15706..15753
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0006"
                     /evalue="5.00E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="AFV96142.1"
                     /protein_end="1054"
                     /protein_start="1038"
                     /score="18.5"
                     /tool="antismash"
                     /translation="GPVVAIDTACSSSLVA"
     CDS_motif       16126..16173
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0007"
                     /evalue="1.20E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="AFV96142.1"
                     /protein_end="1194"
                     /protein_start="1178"
                     /score="11.4"
                     /tool="antismash"
                     /translation="YVEAHGTATPLGDPIE"
     aSDomain        16837..17721
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96142.1_PKS_AT.1"
                     /evalue="4.40E-113"
                     /label="AFV96142.1_PKS_AT.1"
                     /locus_tag="AFV96142.1"
                     /protein_end="1710"
                     /protein_start="1415"
                     /score="369.4"
                     /tool="antismash"
                     /translation="LFTGQGSQYVDMGRELYSTQPVFRKTLEECDRILRLYLDKPLLNI
                     LYPASGDTSVIDETAYTQPALFAIEYALVQLWKSWGIQPDVVMGHSAGEYVAACVAGVF
                     SLEDALKLIAHRGKLMQALPANGKMVSVMADEATVTAAISSCRWEVAIAAYNGPESIVI
                     SDQQDKVDVVKALLEDKGIKTKELNVFHAFHSPLMEPMLAEYETIATQVSYKTPQIPLI
                     SNVTGKRVDESIASAKYWVRHVKEPVKFAQSMETLNAQGNFIFLEIGPKPILLGMGRQC
                     LPSDVGVWLPSLRQ"
     CDS_motif       16840..16887
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0008"
                     /evalue="1.00E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="AFV96142.1"
                     /protein_end="1432"
                     /protein_start="1416"
                     /score="20.9"
                     /tool="antismash"
                     /translation="FTGQGSQYVDMGRELY"
     CDS_motif       17014..17073
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0009"
                     /evalue="1.90E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="AFV96142.1"
                     /protein_end="1494"
                     /protein_start="1474"
                     /score="14.6"
                     /tool="antismash"
                     /translation="AYTQPALFAIEYALVQLWKS"
     CDS_motif       17077..17199
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0010"
                     /evalue="1.90E-28"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="AFV96142.1"
                     /protein_end="1536"
                     /protein_start="1495"
                     /score="91.0"
                     /tool="antismash"
                     /translation="GIQPDVVMGHSAGEYVAACVAGVFSLEDALKLIAHRGKLMQ"
     CDS_motif       17485..17517
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0011"
                     /evalue="2.40E-03"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="AFV96142.1"
                     /protein_end="1642"
                     /protein_start="1631"
                     /score="10.6"
                     /tool="antismash"
                     /translation="PQIPLISNVTG"
     CDS_motif       17551..17586
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0012"
                     /evalue="9.30E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="AFV96142.1"
                     /protein_end="1665"
                     /protein_start="1653"
                     /score="12.7"
                     /tool="antismash"
                     /translation="YWVRHVKEPVKF"
     aSDomain        18181..18369
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96142.1_PKS_PP.1"
                     /evalue="1.90E-09"
                     /label="AFV96142.1_PKS_PP.1"
                     /locus_tag="AFV96142.1"
                     /protein_end="1926"
                     /protein_start="1863"
                     /score="29.6"
                     /tool="antismash"
                     /translation="AADSETRQQLLRTYIGQILAKVVGISPAALNWQKRLSELGFDSLM
                     AADLRKTIDSNLKVAVPV"
     aSDomain        18571..19242
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AFV96142.1_Thioesterase.1"
                     /evalue="2.60E-44"
                     /label="AFV96142.1_Thioesterase.1"
                     /locus_tag="AFV96142.1"
                     /protein_end="2217"
                     /protein_start="1993"
                     /score="144.2"
                     /tool="antismash"
                     /translation="RLFCFPHAGASSYIFNSWPEKFASKIEVCPIQLPGRGNRVKEPAF
                     TKIKPLVQTFAPLLKPYLDVPFAFFGHSMGALLSFELARELRRQNYPNPDYLFVGGYRA
                     PHIPDLNLPIYKLPEPKFIQAISGYGGIPENMLQDPFFLQTFLPTFRADFELLDTYFHT
                     KEEPLESPIYIFGGLEDHTVGIKELSGWEEQTKANFKLKMFNGDHFFLRGVEDEIINII
                     EE"
     CDS_motif       18766..18828
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AFV96142.1_0013"
                     /evalue="1.20E-05"
                     /label="NRPS-te1"
                     /locus_tag="AFV96142.1"
                     /protein_end="2079"
                     /protein_start="2058"
                     /score="17.9"
                     /tool="antismash"
                     /translation="PFAFFGHSMGALLSFELAREL"
     CDS             19362..20483
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:chalcone and stilbene synthase domain protein
                     (Score: 276.3; E-value: 4.8e-84)"
                     /gene_kind="biosynthetic"
                     /note="CylI"
                     /product="type III polyketide synthase"
                     /protein_id="AFV96143.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 1.7e-10,
                     bitscore: 30.4, seeds: 21, tool: rule-based-clusters)"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 5.2e-26,
                     bitscore: 81.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYIVSTSTAFPENYYPQTVLAAALRRFFTVMELDFDLEQIDRFF
                     TNVKIDGRYFALPLDSLLDPPTWGVSISRGLENSLNLAETAITKLLEKTNVQPQDISLL
                     ASVSMTPAIPSLDGRLMNRIPFSSTLKRLPMNGVGCMGGAFGISRVADYLKAHPKEAAI
                     LFAVEISSALWQGSLQANLTSLIRRLPENPSLYSEIIMDIITAALFADGCGAVLMVGKE
                     HPLAKSGLPQVIDNRSFLVPNTVELMGLDVVDNGFRNILRPEVSDALKQGLRPLINGLL
                     ADNNIESENLYRWIVHPGGPKVIDTVEAEFGLDSQTLQLSRDTLAEVGNISSATVLYML
                     DKVLSEEQSPPDSYGLIVAMGPGLAQEAILLKW"
     CDS             20495..21094
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1150:isoprenylcysteine carboxyl methyltransferase
                     (Score: 166.6; E-value: 7.6e-51)"
                     /gene_kind="biosynthetic-additional"
                     /note="CylJ"
                     /product="phospholipid methyltransferase"
                     /protein_id="AFV96144.1"
                     /transl_table=11
                     /translation="MLTRYIFIGIIFVVFLQRMFELRISRNNEAYMLAQGAKKHSDNLL
                     GAVKVLQISWVIASISEIWYFNRPFSFALAAVALSLTIAGQVLRYLSMQALGKRWTLSI
                     ITLPDMPVVDKGIYLYLRHPNWLGVILEIAALPLIHGAYLSAIIFSLANVFLMSKRIQT
                     EEEALVKNSNYTSVFSNRPRFIPKIPLTYQATSGGE"
     CDS             21475..23430
                     /codon_start=1
                     /note="CylK"
                     /product="hemolysin-type calcium-binding region"
                     /protein_id="AFV96145.1"
                     /transl_table=11
                     /translation="MSDVLPDQLQTYIRTVLQFSGRPEGANLLTGPNTEIEFFSQDPNK
                     NFPNIFAKYSNVLTVSSDPNFITSEDEEVKIIWGRHGSDSLIGFDPGADLVGKRRIDIF
                     LGDFIDEQFNPIPGALNAGKSWSDRFILGDWQKPYYFEDDETLGLNQSAMILDFNPNED
                     VIQLHGDRQDYELVNISLGTAIFWREKKGYDLIGVLGGVSDLSLKGDYFEFKGNTAPKT
                     VLKTAEHIGTAANDYIFSSTVDAKGNFYVGGGTGGSLGGRNIGARDAWLAKYDSNGNQR
                     WSRQFGSTGTESLWGMASDGSNIYVAGNTTGQLENNTVKGGNDAYLAKYDSDGNQVWIK
                     QNGTYTLEESYKITVDSSGNIYTAGHTFGSLGGPNQNLEQGEVFELPSTDGYVAKFDSN
                     GNQLWVAQFGTITLDDNWGVAADNNGNVFAGGNTKGSFGAKNTGTAGEYDAWLVKLNKD
                     GQTDWVRQFGTPNYDFMWDIETDSLGDIYATGWTLGDLGGKNAGSYDVWLAKYNTNGNQ
                     LWIKQFGTSEDDAPFLDGIDIDANDNIFLTGNTNGNLGGANAGSYDAWAAKFDKDGNQL
                     WLKQFGTPDYDTATTVTAVNFGKLYVSGITEGSLGTTNAGSYDSWALKLDADNGEIQDF
                     NSSTNTFGQTGFLNLG"
     CDS             23972..25579
                     /codon_start=1
                     /note="CylL"
                     /product="choline dehydrogenase-like flavoprotein"
                     /protein_id="AFV96146.1"
                     /transl_table=11
                     /translation="MKIQAKYCVIGTGAGGGIVAYKLAQSGQDVVVLNTGKLPEQNIFE
                     NELTAEQKYNFGIGKNITFPIKDQADFSEELYADVPDKSTTKIPPEVFLHFQIQHINGL
                     QNLWNGICLRYSQEDFANRHNHNGNCQWQVSYEEMADHYSAVEKLAFVVGSQDGLSQFP
                     DGDFMPPKQLRDIDELFLSSNKYLEHPELVFFNNRKAIDLREYSIQKCVSCGRCFSGCR
                     SGSVYRFSTHLYPQIKQLKNFRLFEYARVIKVASEPGQKAKVMALDERNHTAVEVYADV
                     VIISAGAIESARLLLNSFSIQYAGMDQVGKYLQDVPSVGLGTSLMKTWFKPVSANRGYG
                     DHVLVGGKLKAKDTKFPFVAQFWSDFMKDPIYLNDINFLPRPLKKIVAKQIYRSTAALI
                     LWGPSVPRKENRLELSNDLDRYGQRQLNVLYQRDPLELVFNQQLEKLGRKLLRNASGFV
                     ASRFASRPGKGIHYSGTCRMGATPDQGVVDKNLKFYGADNIYICDGGVIPQLSEKHPTL
                     TIMALAHRLGEHLIRKYS"
ORIGIN
        1 aatttagtca attcttctct tgtcttggaa tgactttttc agcaaaccct aaataatttt
       61 acctatgatg ttcgttagcg atggcaacga gaacaccgca ggcatcgctc tccagatggg
      121 gtcatctcac aaaatcacgt tgctccccag gccactaccg tcttctggcg tacatctaat
      181 ccagcacatc ggggatgaat gacttccatg tttcttctcc ctcattcact ttagacgacc
      241 ggcatggaca cctggatgtc aaattctgac ttacgtgctc tcttagggca aatgcatcta
      301 aattactctt gatcacaacc aaggttaaga accaacaaaa aaatcggtat ttatcgtttg
      361 gttgattttc ccagactcaa agcgatgtct acgacgggtc atgcctacgc taatttagtg
      421 tcaatcagca gttattcatg cgactaattt tgagttattg agaataaaat ccttctattg
      481 acatgatgcg ttcgccctgc gtgctctccc aatcgggggc gacagtttgt ggtgcttgaa
      541 ggtatccagg tcagactatt gggcaggctc tgagcaccta aattaatttt tgttaagtct
      601 caaacaaagt taattttatt tttctctgaa aactaaaagt cttataaatc aagggtttta
      661 gacttttatt tgatgaaaat ataaaagacg gttcactatc atcaggattg atcgcataat
      721 tcgtatcaat acaactgata tataagtaac gtcactttgg gttaagggtt caaatttgat
      781 gacttggacg aaagaataag attcacacat attttttagc ttacatacta gcgtaaatat
      841 actgactctg ctatagtaag ttttaggtag atgtaatgcg tttaaaagtg cttgtaaaat
      901 tcataaaacc aggagctata catattcgta ttagatatag ctattgaaaa gcagttttat
      961 gaatactttc tatattgcac tgactgcttg ggcttggaag tttcatcaaa taccagcaac
     1021 gtattttgtt gtttgtttta tcacctaata aaatggagaa gaacaaagat gcatttgcta
     1081 caacaagaaa atctatcttt gatagaaatc atcaattata gagcccaata tcaacccgat
     1141 aaaaaagcct acatctttct gcaaaacgga gaagaagaat cagcaagtct cacctacggg
     1201 gagttagaca gaagagcaag agcgatcgca gctcgtcttc aatcttggca aggagagcgg
     1261 gctttattgt tatacccttc tggattagag tttattacag ccttctttgg ttgtttgtac
     1321 gctggggtag tggcgatgcc agtttatcct cccaaacgta atcaaaagtt atctcggttg
     1381 ctctctatcg ttaatgatgc ccaggctaac ttagcactga caacctcatc aatattgctt
     1441 gacattagtc aaaagtggaa agaggaaaca gagtcattaa cccagttgaa ctgggtgcct
     1501 acagatacta ttgaagctga ttctcaagat tttgtaccta cattagtaac acctgagagt
     1561 ttggcgtttt tgcaatatac ttccggttct acgggaacac ccaaaggggt gatggttact
     1621 catggtaacc tgatccacaa ttcggagtgc attaagcaag catttgaact cacatcagac
     1681 agtgtatctg tgagttggtt gcccactttt catgatatgg gactgattga tggagtactt
     1741 caacctttgt atactggttt tactggttat ctaatgccac ctgtagcttt tctcatgaaa
     1801 ccggcttgtt ggttgcaggc aattacccga tataaggcta ctcactgtgg aggtcctaac
     1861 tttgcttatg atttgtgtgt gagtaaagtg acttccgaac aactcaaaac acttgacctt
     1921 agtagttggt atacagctta cagtggttca gagccagttc gtaatgaaac cttgaatctt
     1981 tttgtcgaaa aatttagaga ttgtggtttt aaagagaatt ttttctatcc ttgctatgga
     2041 atggcagaag caactctatt tatttctgga ggtttcaaac aatctcctcc tatcgttaaa
     2101 tgtctacaag cacaaacttt aaaggaaaac ataatagtag atgtaactca tccaactcca
     2161 tcttctcaag aagcaagtaa agtgttagtc ggatgtggtc acagttggtt agattacaaa
     2221 attgttattg ctgatccaga gtcttttgaa ctttgtgcag atgggcgagt cggagaaatt
     2281 tgggtgtcta gtgctagtgt tactaaagga tattggaatc gtccacaaca gactcaagaa
     2341 acttttaagg cctatttgaa agatggttta ggtccatttt tacgtacagg tgatctaggc
     2401 tttttgcacg atggtgagtt gtatgttacg ggacgactta aagatattat tatcatcagg
     2461 gggcaaaacc attatcccca agacatcgaa ctgacagttc agaaaagtta ctcagcactg
     2521 cggcttaatt gtggggctgc ctttaccata gaggtcaagg ggaaagagca attaataatt
     2581 gttcaagagg tagaacgaac ttatctaaaa aagttggatg taaatcatgt attagagatc
     2641 attactcagg cggtggcgac agagcatggt ctacaggttt atgccacggt cttggttaag
     2701 actggcagta ttcctaaaac ttctagcggg aagattcagc gtcatgcttg tcggactaaa
     2761 ttcttgaatg caagtttaga tgtagttgaa gattggagcg aaaatcctca atataaatcg
     2821 ggatttatcc gtcttcagga tgaagttgaa tctgtattca atacctttgc caaaaaaaga
     2881 gaatgaagag agagggtcga tgtaatatat ttattatctc tcacaacaaa aatgtattac
     2941 atggcttatg tgaattaaat gctgaaacca ttgtaatacc cagggtaagc gcatctcaaa
     3001 cccgattgac acggtagttt tggcgttctc cgttcattag atagagagca aaaactggac
     3061 accgcgccta aaaaaggact tgacattaag gctcttgcat ggtcatagag tgagactaaa
     3121 ggtttaaacc tcaatttctc taattttttc ggcaattaac cccaatttag accgaatttt
     3181 aacatttcac ttaccatgcc ttaacattat tgtctgtact ttgtgctaca aaattagatg
     3241 cgcttaccct gttgtaatac cgtcgatgat tccaaaatta tcgttctagg caactctaga
     3301 agccctgata aaacaacaag aattttaact cacataaggc gtattatatg tttctctatt
     3361 cttcaatatg aagatattga aaccccaatc gatcatgcta caactattaa aggtaaaaat
     3421 ggaaatcgta aatagtcaga ttaattcaat ctcggtcgat gcagaaaaca atcacgcccg
     3481 tgccaagaaa ctacccacaa aggtagaaat tcaaacctgg ctagttaact acctagtgga
     3541 acagctagac ttaaatccag ccagagtaga tgtctcaatt ccttttgaac gctacggcat
     3601 tgattctgct gctgcaatag tgttggtagg ggatttaaaa gattggttgg aaatagacct
     3661 agagccaact ttaatctacg attatccatc tattgaagag ttagcccggc acttgaatga
     3721 ttcaattaaa gcagaatatt catgataaac ctgtaagcac cagcagtcat cagccgtaaa
     3781 tcttaggctc tgtgaaatcc caaatttcca ccataattgg tactgcttga aagggtgttg
     3841 gaaaaattta gggttttgag catcctctga gccatttatt acaaaacttc tctctcatgt
     3901 agctcttcga ttacctaaaa tttaattaat cgaggttccc tgacgttacc tgatggtaat
     3961 taatcaacgt ttctaattat tcactttgag gtaaaactaa caatgactag cgttaatgta
     4021 aagcttaaag acgaggaatc gtcaacccta atagagaaca ataaaaagaa gcatctaaaa
     4081 gtcactgaaa tcacttataa gaacaacact gaatccaact acacagaaaa aatagaggag
     4141 ttggataaaa gctttaacta cagtgacaac agcaatcatt actggagcca tcctgaactg
     4201 tcaatttttt acggcactcc gctttatgca gaagcctcac actcacaaaa aattgctctc
     4261 aatcatcttt attgggtgac gcagtatagc cagatcgctg ctagtgaagc aaacaccata
     4321 ctttacaatg atgtgaccaa tggagtgttt ttcgctgttg gtggctatga aatgctctgt
     4381 aaagaattag atttggagag caaccaggaa aaatcccaca ttcatgcttt tcataccatc
     4441 agttataaaa ctaagaaagc tctgctggga aaagcagcat tgaccacacc tgtagagcta
     4501 aatcaaagcc aagctctgga aaataattcc caagagaatg cagctagcaa agctttgcaa
     4561 aaattattag gttacaagcc cctaagttcg acacctttag ctttagaaga tgctgccctc
     4621 cgcttactaa aaaatatcag actcaaaagc aaagcagact gctattcccc ctatttacat
     4681 gaattggaga agaaagattt atttcttcca ggccccagaa caggtatatt aagagtcttt
     4741 cctagatatc tgctgaggtt gtttacctta agttggggaa gttcatcttt cttagcttct
     4801 cagtattact gcttccgcta catagcaaat atgctgctca aaacagctga atatgaatat
     4861 acaaggcatt acagagactt agaaaaaaca ggagatttta tcccaaatcc aacagaagtt
     4921 tcccgttacc atttgttgga tgaatcttac cacaccacaa tgtctaaact gattgctcaa
     4981 gatgtataca aggattttgc taaaccaaca gcatatgaaa gatacatggg caatttgtca
     5041 gtcaaagtaa cgcaaagccg tctgcttggt ggtctttctg gcggtttacc tgccatattc
     5101 caagacgatt cctggttcac actttcatac tacaagttac tccgcagtcc tatcttcaat
     5161 atgtctcacg aagaaactct gcactggttg gagaaatgct tgtgtcatga acatgaaggt
     5221 tttcatgtca atctcaagta tcaccatcgc ctgttaacag acctgcgtta ctttttcggc
     5281 gaattcgatt atatgtggcc tgttaaccgg gaaatgagct tgatggctga agggggatcg
     5341 cttgaaaaag ctatccaaag aaatatcgag tcctttagag atttttctaa atcttttacc
     5401 aagggggcta taaaatagcc ttaaaagcgt tattaacgct aaaaacctaa tttattaggg
     5461 ataaaagcca gaaaaataag acgttgcata atagagggat aaattgaaga tatatacttg
     5521 caatgtccat aatgtggatc tatgtatatc tacagtatga aaatgtacta aagcaaattt
     5581 atccctttat taagcaacgt taaaaataaa atgtgctttt ttgcaaaata aatgcttgta
     5641 ggaagaggtc aagatatgac aatggaagca atagctatta ttggaatagg tgttcgctcc
     5701 cctggcgcta aaaaccctga atctttctgg catctcctac gtgaaggtgt agatgcgatt
     5761 actgaagtcc ccctagaacg gtggaatgtt gatgaatttt acgacccgaa accagccaca
     5821 gcaggcaaaa tgattactcg ctgtggtggt tttgtggatg aggtagatag ctttgatgct
     5881 ggtttttttg gcatttcccc ccgcgaagcg gaatgtatgg acccccagca aagactggtt
     5941 ttggaagtag cctgggaagc cctagaaaac gcaggtatag caccagacaa gctaaatggt
     6001 agccaaactg gggttttcat gggaattggc aactacgatt atggcaggtt gcaaagctgg
     6061 catttctctc gcctcaacgc atacgatggc acaggcacca gcctcggtgt tgcggctaat
     6121 cgcttatcct atgtgctgaa cctgcatggg ccgagtttag ttatggaaac ctcttgctct
     6181 tcgtccctgg ttgcagtcca ctatgccagc caaagcttac atagcaaaga atccgatctg
     6241 tgcttggtcg gaggtgtcag tttaatactg tcgccggaat cacatattat tttttcccaa
     6301 gcgagaatga tggcacctga tggtcgctgt aaaacctttg atgccagtgc tgacggttat
     6361 gttcggggag aaggatgtgg tgtaattgtt ctcaaacgtc tctcagatgc gctcagggat
     6421 ggagacaaca ttctggcaac catcagaggt tcagcagtaa atcaagatgg tcggagcaat
     6481 ggactcaccg cccctaatgg gcctactcaa caggctgtta tccgtaaagc tttagaaaac
     6541 gctggagtta cggcagatca aattagctat gtagaagctc acggtacggg aacctccctg
     6601 ggagatccta tagaatttaa ctccttaaaa actgtattaa tgaagggtcg ccaaccgact
     6661 caaacctgtt atattggctc agtcaaaaca aatattggtc atttggaacc agctgcgggg
     6721 attgttggct taattaaggt ggtattatcg ctgcaaaata agcagatacc ccctcacctg
     6781 catttcaagc agttgaatcc atatataaaa attaataata ctcccttgac gattcccaca
     6841 gcactacagg aatggaatgt tgatcaagga tcgcgtttag ctggtgtcag tgcttttggt
     6901 tttggtggta cgaatgctca cgtcatcttg gaagaggctc ctgagtcggt ggcagtagta
     6961 aaaaatatag agcgtcctca gcaattactc gctctatccg ccaaaagtgg taaggctttg
     7021 caagagctag tacgaagtta tgaagcgtat cttgagtccc atccagagcg atcgctagag
     7081 gatgtgtgtt ataccgccaa tacggggcga tcgcatttcc cccatcgtct agctatcatc
     7141 gcctcccaca aacaagaatt agctgacaaa ttatctaaaa tcagtgcaga gcaagaagtt
     7201 aatcaagtat tttttagtca aaattctggt gatagcatat caccaaaaat tgccttcctg
     7261 ttcactgggc aaggttctca atacatcaac atgggaagac aactttatga aactcaaacc
     7321 gtcttccgtc aaaccataga caagtgcgag caaattctcc aatcctattc agaaaaatct
     7381 cttttagacg ttctttatcc tgaagataac caacaattaa ataattctct cattgaccaa
     7441 actgcttata ctcaaaccgc tctatttgcc attgaatatg ccctagccca actatggcaa
     7501 tcctggggca taaaaccaga tgtagtgatg ggtcatagtg taggagaata tgtagccgca
     7561 acagtagcag gagtatttag tttagaagac ggattaaaac tgattgccca tcggggacgc
     7621 ttaatgcaaa gcttacctga agggggtgag atgttagctg tgatggcaac agaggagaaa
     7681 ataaatcaac tcatcgcccc atacacagaa aaagtggcaa tagcagccat caatgagcct
     7741 ttcagcattg tcatttccgg cgcaggagaa gtcattagga ctctgaggga cagcttaaac
     7801 gcagaaggaa ttaagacaca ccagctacaa gtatcccatg ccttccattc gcccctagtg
     7861 gaatcgatat tggcggagtt tgaggcaata gccaatacaa taacctacaa tcaacctcag
     7921 attccactga tatcaaacgt ctcaggaacc aaagcacacg agaatattgc cacagccagc
     7981 tactgggtaa atcatgcacg ccaacccgtg cattttgccc aaagtataaa agtcttgcac
     8041 caagaaggtt atgaaatctt tctagaaatt ggacccaaac caattttgtt aggaatgggg
     8101 cgcgaatgcc tcatgggaaa taaaaagcta tggttgccaa gtttacatcc tagtagacca
     8161 gactggctac aaatgttgca aactttaggg cagttatacg cacaaggagt caaggtagat
     8221 tgggcgggat tttacaaaga ttattcctat cagaaggtag cgttacccac atatccttgg
     8281 caacgaaaaa ggtattggat cacaaatatt caggaaggca aaaatcaaga caagattagc
     8341 ttaatctctc aaggcgaaac aacaagaact aatgggaata tacaatctca ggaaagacaa
     8401 atgaatgaaa acaaaatatt acagcaaaca aagctgacat tatccaatcc agagttactg
     8461 tcttttccga aagctccatt aaaaacagaa gaaacaccca caaggcagct agctcagttg
     8521 acagttccat caattcaggt agaacctgct gaatctactc aaccacaagt tgaatcggga
     8581 aatattgccc aaacacgaag catatcagca ttaaataact ccaatggtaa tgtgaatcaa
     8641 atcaaacaga ccctcaagga aagtctagcc tcagccctgt atacagatat tagtgaaatt
     8701 gaagaagata aaaaatttat tgatttaggc ttagactcta tcgtgggagt cgaatggctc
     8761 accaccatca atcaaaccta caatttaaat atcaaagcaa ccaagctcta cgattaccca
     8821 accttattag atttagcgaa atacatcacc caggaaattt cctcaatcgg tggaagcaga
     8881 ttagccccaa ataatcaaga ctctccaaaa gaatctccac aaaatcagga ttcatctgga
     8941 gattcacaag aagacttgag gcataaatta cgatcaatac tgaataaagt cgcaaataaa
     9001 gaattaactg ttcaagaagc aaatcaaatc attcaagaaa tcaaacaaaa agctgcatct
     9061 agtagtaaat ttcagagtaa cggcacaaat aataatcgaa tatttcaaat cattaaaaaa
     9121 tccatttatg aggtagaacc caaattagaa agagcccccc tcaaaaccac tgatagccta
     9181 agacaattag gaattgattc agtcaaccga gcagaaatta tgacgatagt tatggaagag
     9241 ttagatttgc atatcccact aattgaatta gctggagcgc aaaacattgg agaattagct
     9301 gatttatttg caactaaatt ggaagcgcat catgggatat agctttgcac caataagaat
     9361 agagataact ggtatgggaa ttgttactcc tattgggcaa ggagtagcag cttttcgtga
     9421 tgctctgttg gctgggaaaa ctcagtttgg ttatctcaaa cgatctggac gtgaaggatc
     9481 taggtcattt attggtgcag aacttccaga cattagtgct aaatctttgc tccccgaaca
     9541 tagcggattg ctacgcacag cttcatggag tagccagata gcaagcgtag ctgtttctga
     9601 ggcttgggaa gatgcacaac tgtcttcagg caaagtgaac cccgaacgta ttgggattgt
     9661 agtgggcggt tcaaatttcc aagaacgtga taaacaacaa atctggcagc gttaccaatc
     9721 gaatcctgag tttatacgac caacttatgg cgttaccctt tgggacaccg atgtaatgag
     9781 tttgctctcc cagtgttttc agattcaagg cgaaggctat agcgtaggtg cagcttctgc
     9841 tagtggagca gttgctataa ttcatgctgc ccggcaaatt ttaatgggga tcactgacgt
     9901 gagcgttgct gttgggtctt tgtttgatat ctcccaatgg gaatgccagg gattcacgaa
     9961 tttaggagct atgggcagtg cgcgttttgc cgatactcct gatcttgctt gtcggccatt
    10021 tgatcgagat catgatggct ttatttatgg agaaggttgt ggagttttag tcctcgaaag
    10081 aactgaccat gctcaacaaa gaggagtaag gtctcatggg gaactcattg gctggggatt
    10141 aggtttagat ggaaaacgga ctcctgagcc atctcaaaaa ggagaagaac aagctatgaa
    10201 tgctgcccta gcgatcgcaa acctgaagcc agagcagatt gattatgtga atactcacgg
    10261 cacaggctct cctttaggtg acaagacaga agtagctgcc ttgaaatctg taggactatc
    10321 tcactgtttg ctcaattcca caaagtctct gacaggtcac tgtttaacgg cagcaggagt
    10381 cgtggaggtc attgccactt tattgcaaat gaagtttggt ttttgtcatc cgacccataa
    10441 cctagttaat cccattgata ccaccctaaa ttgggttaaa gaaacgtcta ttaaagctga
    10501 aattcaatat gccatcagta acagttttgc ttttggggga atcaatacag ctttattaat
    10561 caaaaaggag taaatctgtg caacaagtgg gaattgaagc tttaaatata tatggaggcg
    10621 catctcaatt agatgtgcgg atgttggcac aagcacgtca cttggacacg agccgcttcg
    10681 acaatctgat gatgaaagag aaagcggtct ctctgcccta tgaagatcca gtttcttatg
    10741 ctgttaatgc cgccaagcca atcatcgatc gcctgagtga ttctgacaag caacgggtag
    10801 aaatggtcat tacctgtagt gagtctggca ttgactttgg caaatctatg agtacttata
    10861 ttcaagatta cttagggctt agtcgtaact gccggatgtt tgaactcaag caagcttgct
    10921 actcagggac agccggcttg cagatggcaa tcaactttat tttgtcccaa acatctccag
    10981 gagctaaagc tttagttata gccactgata tatctcggtt tacccttgca gagggaggag
    11041 aagctcttag tgaagattgg tcttttgcgg aaccgagtag tggtgctggg gcagccgcta
    11101 ttttggtaag tgatgttcct tacatttttc aagttgatgt gggatgcaac ggctactatg
    11161 gctatgaagt aatggatacc tgccgaccca agccagattc agaagcggga gatgcagact
    11221 tatcattgct ttcttactta gactgttgcg aaaatgccta cctgcattat caaaagcgag
    11281 tagaaggcgt ggactaccaa aaatcttttg attacttgag ctttcatacc ccctttggag
    11341 gcatggtcaa aggggcgcac agaaatatga tgcgtaaatt gaaaaaggct aaacctgaag
    11401 agattgaagc agactttcaa agaagggtga tgccgggatt agtctattgc caacaggtag
    11461 gcaacattat gggggcgaca gtgtttttag ccctggctag cacgattgac aatggggatt
    11521 tcagccaacc tcgaagaata ggtatatttt cttatggctc tggttgttcc tcagaatttt
    11581 atagtggggt tgtgactcca gaaggaaagg aaattcaagc tcaacaaagg atttcatcac
    11641 agttagcaac gcgctattcc ttaaacatcg aagaatatga gcagttacta cattacagtc
    11701 gcgtagttgc ctttggcacc agaaatgtca ccctagatta caaaatcttt cctggtgtgt
    11761 ggaaacaaat tgaaggtaag ggtcgattag tactcaaaaa aatcaaggaa tttcaccgag
    11821 aatatgaatg ggtataaaca tggactatca aaccctaaaa atcaatcatc aaagtgctgt
    11881 acaaaggatt cagatatatc gacctgaagc taacaatagc atcaatagtc aactgattca
    11941 agaattgttg tcagccttgc aagctgccga agcagaagaa gcagtgaaag tggtgatcct
    12001 agagggacta cctgatgtgt tttgtacggg aatggatttt caagaaatag cagacggaaa
    12061 acaagtcgat ccaaaaatga gttctcatgg ttactacaac atcctcaaac aaatgtcaca
    12121 atgtagcata gtgattgtgt cacttgtgcg tggcaaggta caagcagggg gagtgggttt
    12181 ggtagcagcc agcgatatag ttattgcaga tgaaactgtt acatttgttt tatcagaact
    12241 attatttggt ttattaccag cttgtgtatt accttttttg attcgtcgaa taggatttca
    12301 aaaagcttac cgtttagcat taacaactca agaaatctca gcatcagagg cttataactt
    12361 gggcttgatt gatgaatatg gcagcaatac taataagtta attagtcaat acgttaaacg
    12421 tttaaaatat ttaccctcat ctggggtgag ggagttaaaa aactatataa atcaattatg
    12481 gattattcaa gcagaaactc aagatttagc tgttaataaa atttccagtt tgttagatga
    12541 tcctactgtt caagaaaaaa ttaagcgctt taaaaatgag ggtgtatttc catggcaagc
    12601 ctgaatttta acctggactc agcaaagggc aattccgagg tagtacaact ggtagagttg
    12661 ggtaatggtg ttgttaaaat cacgatgaaa gatgaggaaa accataatac attttcttca
    12721 gaaataattg atgggttata caaatgtttt ggtgcagttg ctcaaaataa gagctataaa
    12781 gtagtaattt tgacgggcta tggaaattac ttttgttcgg gagggacaaa ggaagagtta
    12841 atcaaaattt acaaaggaga actgcaattt aatgagttag atttttttag aatattactg
    12901 gattgtgaaa taccagtaat tgcagctatg caaggtcatg gtattggggg tggttttgtt
    12961 tttgggttat atgcagattt agttgtgttg agtcaagaaa gtatttacac aactaatttt
    13021 atgaagtatg gtttcacccc tgggctggga agtacgttca ttgtacctac aaaattaggc
    13081 tctgtattag gtcaggaaat gatgtacaca gcccaaaact atcgagggaa agaattattc
    13141 aagaagggta ttcctttccc tgttgtaccg agaaaagagg tgctaaacca tgctctaatg
    13201 ttaggctata aaatagccga aaaaccgaga ttatctttag taactttaaa agaacattta
    13261 acttctgaaa tcaaaaaaag attaccagaa gtgctagaaa aagaactaaa gatgcacgat
    13321 attaccttcc atcaactaga ggtagccaat cggattgaga caatttatgg cgacaccaat
    13381 attagtagtc agccacacaa tttgagccaa gaattggtca atgaatcagc agatgttcaa
    13441 aatcaagtgc ctctactgtc gagccagaag aatagacaag aaattattga aaattcaatt
    13501 actcttaaac aggtccaatt aaagatatct agttatggct tattaaataa tttaacttta
    13561 gcacctttgc aacgtagggt tctcggctgt gctgaagttg aggtgcaaat caaagctgtg
    13621 gcagttaatt ttcgggatgt aattaacgcc cttggtatgc tcaaagagta caatgagcaa
    13681 aaatttggca ttaccagtgt tgaaaatctc atctttggtt ttgaaggtgt aggtactatc
    13741 gtggctgtcg gggaagaggt gactcagtgg caagtcggcg atgaggtgat ggtaatcgga
    13801 attcatgatg ccttcagtag cttcattgtc tgctcaccaa ataacctagt ggctaaacct
    13861 tctaacctga gcatggtgag tgcagctact attcccatac ccttttttac ggcagctcac
    13921 ggtttgtata acttagccaa aattcagcca ggagaacgag tattaattca tgctgctgcc
    13981 ggtgggactg gacaggcatc agttcagtta gctcaactca tgggcgcaga agtatttgct
    14041 accgctagtc caggtaagat ggcttttctc caaagacagg gaataaagca tatcatgaat
    14101 tctcggacta ctgagtttgc cgatcaggta atggaactaa ctcaaggctg cggggtggat
    14161 gttattttta atagcctgac tcatggagag tacatccaga aaaatataga tatcctggct
    14221 ttgggaggac gatatgttga aattggtaag ctgaacatct ggagtcatga gcaggtcgct
    14281 cagaagcgtg cggatgtcaa gtattttcct tttgatttag gggatgaatt tgctaaggat
    14341 agtcaattgt tttcccggat ctggggcaag ttggcacaac attttgagcg cgattacctg
    14401 aagccattac attacaaaga atttccgctt gaagatgttg ttgaatcttt ccgttacata
    14461 cagcacagta agcatatcgg cagggtagta gtaaccatgc cagagtcctc ctattggggg
    14521 gaagaatcga atggcgatcg cctatctaat caaaacaagc taattaatca ggaagatgta
    14581 ctgcatcaat tacaatcggg tgcagtttcc ttggaggaag cagagaaact gttgttaggc
    14641 tttactgaag aagtagaaga aactcttgag aaaaagccca tcgagaatgg tcacaacaaa
    14701 ctgattaatc aggaagatgt actgcatcaa ttacaatcgg gtgcagtttc cttggaggaa
    14761 gcagagaaac tgttgttagg ctttactgaa gaagtagaag aaactcttga gaaaaagccc
    14821 atcgagaatg gtcacaacaa actgattaat caggaagatg tactgcatca attacaatcg
    14881 ggtgcagttt ccttggagga agcagagaaa ctgttgttag gctttactga agaagtagaa
    14941 gaaactcttg agaaaaagcc aatcgagaat ggtcacaaca aactgattac taaagatgac
    15001 tcggagtcaa tattatctct acagagtgca ggagcaatat ctttagaaaa tatcgagaat
    15061 ggtcacaaca aactgattac taaagatgac tcggagtcaa tattatctct acagagtgca
    15121 ggagcaatat ctttagaaaa tgctgaaaaa ttattattag aaaaaacagt agaatcagaa
    15181 actaaaatca atactgttat ttccaagctt gttaagaata cggatatagc tataattgga
    15241 atttcctgtc gatatccagg agcgaaaaat tggcaagaat tttggaaaaa tttaaagaat
    15301 ggaattgaca gcgtaacgga agttcccccc ggaagatggc aagaaaaaga atggtatcat
    15361 ccagacccag aacatgtagg aacttcctat tcaaagtgtg ctggtttctt agatgaaatt
    15421 gataaatttg accctttatt ctttcaaatt tctccagtag aagctcagtt tattgagcct
    15481 cagcaaagaa tatttttaga agaagcttac cacgcgattg aagatgctgg atatgctact
    15541 gattctctca agggtaaaca gtgtggagta tttgtaggag caggaacaaa cggtgattac
    15601 aacaagttat tgtcaattgc cggattagat actcatcgac tggctctaac aggaaatctg
    15661 ctgtcaatga taccagcaag aatagcttat ttccttgacc tgagaggtcc agtagtagct
    15721 attgatactg cttgctcatc ttcattagtc gctgttcatc aagcttgtga aagtattcaa
    15781 cggggagaga gcgaactggc gatcgcaggg ggaattgcca ttatggcaac agcagacttc
    15841 caagtattat caagccagtt tcaaatgtta tcggctgctg gtcgatgcaa aacttttgat
    15901 gcttcagcat cggggacagt ttggagcgaa ggttgcggtg ttgtcctcct caaaagctat
    15961 gagcaagcca ttcgtgataa cgaccatatt tatgcagtta tcaagggtac aggcgttaat
    16021 tatgatggca atactaacgg aattagcgct cccagtggtc agtctcaaac acgcttagaa
    16081 gaaggggttt atcagaagtt tggcattaat ccagaaacca ttagttatgt agaagctcat
    16141 gggacagcca caccactagg agatcctatc gaggttgaag gtttaacagc ggctttttct
    16201 aaatggacaa cgaagaaaca gttttgtgcg atcggctcgg taaagactaa tattggtcat
    16261 gcagcaacct ctgccggaat ttctggttta attaagacaa ttttgtgcct caagaaccag
    16321 aaattagttc cttcgttaca ttttaatcaa cccaacccac atattgactt tgagaatagt
    16381 cccttctatg tcaatacaga atttaaagat tggcaagtaa cagatcgcaa ccccagacga
    16441 gccacagtga gttcctttgg ttttagtggc acaaatgctc atttagtcat agaagaagca
    16501 cctttacaag tcaatagtca aaatttaaga tttccaggtg atgagtttag tcagcgatcg
    16561 caccatctat tgactctatc tgctaagtgt gaaaaaggtc tgcaagagct agtacaagat
    16621 tatcaggaat ttttagagac taattccaca gccgcgctct cagatgtttg tttcagtgcc
    16681 aatacgggac gctcacattt tgactatcgc cttgccttag tagctgaatc tacagaaaac
    16741 ttacttcaac agttaaaggc gtttgcaact ggggaggaaa caactaagct gttaagaggt
    16801 caagctacca gcaaagagcg tccaaaaatc gcgtttttat tcacaggtca gggttcgcag
    16861 tacgtggaca tgggaaggga actgtactct acccaacctg tattccgcaa aaccttagag
    16921 gaatgcgatc gcattttacg cctttatcta gacaaacccc tgctcaacat tttatatcca
    16981 gcatcagggg atacttcagt aatagatgaa actgcttata ctcaaccagc cctatttgcc
    17041 attgaatatg ccctagttca attatggaaa tcctggggga ttcaacccga tgtagtcatg
    17101 ggtcacagtg caggagaata tgtggctgct tgtgtggcag gagttttcag tttagaagat
    17161 gcactgaagc tgattgccca taggggaaag ctaatgcaag cattacctgc taatggcaaa
    17221 atggtgtccg tgatggcaga tgaagcaacc gtaacagcag cgatttcctc ttgtagatgg
    17281 gaagtagcga tcgcagctta caatggccct gagagtatag tgatttctga ccaacaagac
    17341 aaagtagacg tagtcaaggc gctattagaa gacaaaggaa tcaaaaccaa agaattaaat
    17401 gttttccacg ccttccactc tcctttgatg gagccgatgc tggcagaata tgaaaccata
    17461 gccacacaag tcagctacaa aacccctcaa atccccttaa tttctaacgt cacgggtaag
    17521 agggtagatg aaagcatagc tagtgcaaaa tactgggtgc gtcatgtcaa agaaccagtt
    17581 aagtttgccc agagtatgga aaccttgaac gcacaaggaa acttcatatt tttagaaatt
    17641 gggccgaaac caatcttatt aggcatgggt cgtcaatgtc taccgtcaga tgtgggagtg
    17701 tggctaccgt ctctcagaca aagagtaaaa gattggcaac aaatattaaa tagtctggga
    17761 caattgtatg tgcagggaat agaggtagat tggtcagaat ttgaccgtga ctatgctcgt
    17821 tgcaaagtta cattacccac ttatccattc caacggcagc gatattgggt agaaacggct
    17881 aaggatggag ttggacaaca aaaagtacaa tctctaaagc aagagaatac atccagtcca
    17941 atttatcatc tcttgtgtaa aggggaaaca gaacttgtca gcagcgagtt agaaaaatta
    18001 ggagtacttt cgcaagacga aattaagtta ttacctaagc tactgaaact attagttgag
    18061 caacatcaac aacagtttaa aatagaatct aatgctcatc aaaatgaatc tgctaaaacc
    18121 gatgaaaaaa ttgcttcccc gccggcatca gaacccagta ataaaggtga tgaaatcctg
    18181 gcagcagatt cagaaacgcg ccagcaacta ttaaggactt atattggtca aatattagct
    18241 aaggtggtag gaatatctcc tgctgctctg aactggcaaa agcgcctttc tgaactagga
    18301 tttgactctt taatggctgc tgatttaaga aaaactattg atagcaactt aaaggtggct
    18361 gttcctgtag aatatttggc agagctaaat attgaacagt tcttaaccca gatactttac
    18421 ctgattgaac agaagtttcc caaggaacat ctgcaaaaag ccaattcaac gattgatgaa
    18481 caaaaaagtt ccatcaatcc agttaaaaag gttgtagatg aagcccaaaa gtggttcaaa
    18541 gtctcaccga gaaattccca acctcagttt cgtcttttct gcttccctca tgcaggagct
    18601 agctcttata tttttaattc ctggccagaa aaatttgcct caaagataga agtttgccca
    18661 atacaattac caggaagagg aaatcgagtt aaggaacctg cctttactaa aataaagcct
    18721 ctagttcaaa cttttgcacc gcttctcaag ccatatctag acgttccatt tgcatttttc
    18781 ggtcatagta tgggagcact actcagtttt gaattagctc gtgaacttcg tagacaaaat
    18841 tacccaaatc cagattactt atttgttggc ggatatcgcg ctccccacat accagattta
    18901 aacttaccaa tttataaact tcctgaaccg aagtttattc aagcaatttc tggttacggg
    18961 ggaatacctg aaaatatgct gcaagacccg tttttcttgc aaacgtttct tcctactttt
    19021 agagctgatt ttgagctttt agacacatac tttcacacaa aggaagaacc ccttgaatct
    19081 cccatatata tatttggcgg tctcgaagat catacagttg gcataaaaga actttctggt
    19141 tgggaggaac aaactaaagc taactttaag ctgaaaatgt ttaatggaga tcatttcttt
    19201 ttgcgtggag tagaggatga aattatcaat attattgaag agactatttt ctgtacaatc
    19261 aattaaggaa ggcagaaggc aattagatag ggatttagtc cccagctaat taaagaccac
    19321 cctcatcaga gattttgcaa gtaaaacaag taaaatttgc catgacttat atagtttcta
    19381 catcaacagc atttccagaa aattactacc ctcaaacagt tttagctgct gctttacgca
    19441 ggttttttac tgtcatggag ttagatttcg atctagaaca gattgatcgt tttttcacaa
    19501 acgtcaaaat cgacggtcgt tacttcgctc taccactaga ttccttactc gatccgccca
    19561 catggggagt aagtatcagt agaggtttgg aaaattcttt gaacttggct gaaaccgcta
    19621 tcaccaaatt gctggaaaaa actaatgtcc aaccccaaga tatatctctg cttgcgtctg
    19681 tttctatgac tccagcaatt ccctctttag atgggcggtt gatgaatcgg attccatttt
    19741 cttccaccct gaagagattg cccatgaatg gagtaggttg tatgggtgga gcttttggca
    19801 tttcccgcgt tgctgattac cttaaagcac atccaaagga agcagcaatt ttatttgcag
    19861 tggaaatttc ttccgctcta tggcaaggtt ctttgcaagc aaatttaact tcattgattc
    19921 gtcgccttcc agaaaatccc tctttatata gtgagattat tatggatatt atcactgctg
    19981 ctttgtttgc agatggttgc ggcgcagtgt taatggtagg aaaagagcat cctttagcta
    20041 aatcgggact acctcaagtc attgataatc gttccttttt agttcctaac acagtagaac
    20101 taatggggct ggacgtagtt gataatggtt ttagaaatat tctcagaccg gaagtatccg
    20161 atgctcttaa acaaggattg cgaccgttaa ttaacggttt gcttgctgat aacaacattg
    20221 aaagtgagaa cttgtatcgc tggatcgtac atccaggggg ccctaaagta attgatacag
    20281 ttgaagcaga atttggatta gatagtcaaa ctttacaatt aagtcgcgat accttagcag
    20341 aggtaggtaa tatctcttct gcaacagtgc tttatatgct cgataaggtg ctatcagaag
    20401 aacagtctcc tcctgactcc tatggactga tagtagcaat ggggcctggt ttggctcagg
    20461 aagcaatttt actcaaatgg taggacggca ttatatgtta accaggtata tcttcattgg
    20521 gattattttt gtagttttct tgcaacgaat gtttgagctg cgtatcagca gaaacaacga
    20581 agcgtatatg ctagctcaag gagcaaaaaa gcatagcgat aatttactag gtgccgtgaa
    20641 agtgctacaa attagttggg tgatagcatc aatcagtgaa atttggtact ttaaccgtcc
    20701 ttttagcttc gctttggccg ctgtcgcttt atctctaaca atagcaggac aagtcttacg
    20761 ttacttatct atgcaagctt tagggaaacg ctggactctg tcaattataa ccttaccaga
    20821 tatgcctgta gtggataaag gaatttatct ttatctgcgt catcctaatt ggttgggagt
    20881 catcctggaa attgccgcac taccattaat tcatggagct tatctaagcg cgattatttt
    20941 ttctcttgct aacgttttct taatgagtaa gcgaattcaa acagaagagg aagctttagt
    21001 caaaaacagc aattacactt cagttttctc caaccgacct cgttttattc ccaaaatccc
    21061 acttacttac caagcaactt ctggaggtga ataaacatga gttgtaaaag tttatcagca
    21121 ctcaattcta ggtatgtttc atgagaaatt aagcttttga agtgctgaaa acttctcaat
    21181 acttctatcg atcaagttaa gaaaattatt taaatgacaa ataaattacc tgtttaccca
    21241 acttctcgat ggaagaagca caacctatct caaaacctca tacaactggc aaaaatcttg
    21301 gtgatatatc ttatttatta taagatttaa gttgtcacga atgatctcaa caaattctca
    21361 actcaaaagg attgcaatca aatcaatagt ttttactacc atgaaaaaaa caaaaaaaca
    21421 acaaaatcct tactctcagc cgacgaaaaa ataacagagt ccttacgctc aacattgagt
    21481 gacgttcttc cagaccagct tcaaacatat atcagaactg tcttacaatt ctctggtaga
    21541 ccggaggggg ccaatctcct aacaggcccc aatactgaga tagaattttt cagtcaagat
    21601 cccaataaga attttcccaa catttttgcc aagtatagta atgtactgac agtttccagc
    21661 gatcctaatt tcataacatc agaagatgaa gaggtcaaaa tcatttgggg ccgtcatgga
    21721 agtgatagcc taattggttt tgaccctggt gctgaccttg ttggtaaacg cagaattgat
    21781 attttcctcg gtgattttat cgatgaacaa ttcaatccaa tacctggcgc attgaacgca
    21841 ggtaaatcgt ggtcagacag atttattctg ggtgattggc aaaaacccta ctattttgag
    21901 gatgacgaaa ccttgggttt aaaccaatca gctatgattt tagactttaa ccccaatgaa
    21961 gatgtcattc agctccacgg cgatcgccaa gactatgaac tggtaaatat tagcttggga
    22021 acagcaatat tttggcggga gaaaaaaggt tatgacctca tcggcgtttt aggtggagtc
    22081 tctgatttaa gtttaaaggg tgactacttc gagttcaagg gcaacaccgc accaaaaaca
    22141 gtcctaaaga cggctgaaca tattgggact gccgcgaatg attacatatt tagttccacc
    22201 gtagatgcta agggcaattt ctatgttgga ggaggaaccg ggggatcttt aggaggacgc
    22261 aacataggag ctagggacgc ttggctggcc aaatacgata gcaatggcaa ccagcgatgg
    22321 agtagacaat ttggctcaac cggcactgaa agcttatggg gtatggctag tgacgggagc
    22381 aatatttacg ttgcgggaaa caccacaggc cagctagaaa ataacaccgt taaaggcggc
    22441 aacgatgctt atttagctaa atacgatagt gatggcaacc aagtgtggat taaacagaat
    22501 gggacttaca cacttgagga atcttataaa attaccgtcg attccagtgg caatatttac
    22561 actgctggtc acacttttgg cagcttgggt gggccaaacc aaaacttgga acaaggcgaa
    22621 gtattcgagt taccatcgac tgatggctac gtggccaagt tcgacagcaa tggtaatcag
    22681 ttgtgggttg cacagtttgg tacgatcaca cttgacgaca attggggtgt cgcagccgac
    22741 aacaatggca atgtcttcgc tggaggaaat acaaaaggca gtttcggagc aaagaatact
    22801 gggacagcgg gagaatatga tgcctggcta gttaagttga acaaagatgg tcagactgat
    22861 tgggttagac agtttggcac tccgaattat gactttatgt gggacattga aacggatagt
    22921 ctaggcgata tctatgcgac cggatggact ctgggagact tggggggaaa aaatgccggc
    22981 tcttatgatg tctggctggc caagtacaac actaatggca accagttgtg gatcaaacag
    23041 tttggcacta gtgaagatga tgcacccttt ttagatggga tagatataga cgcaaatgac
    23101 aatattttcc tgacgggaaa tacaaacggc aacttaggcg gagctaatgc tggatcttat
    23161 gatgcttggg cggcgaagtt tgacaaggat ggcaatcagt tatggctcaa acagtttggt
    23221 acccccgact atgacactgc taccacggta actgccgtta atttcggtaa actttatgtt
    23281 tcgggaatta ctgagggaag tttgggaact accaatgctg ggtcttatga ctcttgggcg
    23341 ctcaaactag acgctgataa cggagagata caagatttta attcttctac taatactttt
    23401 ggccaaacgg gttttttgaa tttagggtaa atgcaaatgg taggtaaggc tagaacatgg
    23461 ggaataccaa caacttgcac catttttgcc agcaagttaa gtggtatacc tcatgactta
    23521 ccgccatgac aaacaactga taactacttt cgccatgctt ctaagatcca taagtatttt
    23581 cttttgaaac tagaccgact tatcctgata ttaaaacctg aaaatacgta aatatcattc
    23641 ttttgggaat cacattgcta ttaatggtta aaacagtgtt aatagaacag ttaaacgaag
    23701 accaaacgcg aaagaacgaa ttagcgagag acctcgttaa tatatcctca gaagcagctg
    23761 agatcgagca tctagtagag cgtattcctg agatcatgtg tgccaatgac cagctgcgac
    23821 tattttggga gcgttgggaa aaagaaggca tgggtacaaa atctccacac aagttatttt
    23881 ctcgtcaaga aattcgtatc ttaaaagcat tccttgagta tctcagctac gccagcgatc
    23941 gctttatctc acagattcat gaaggtaaat aatgaaaatt caggcaaaat actgtgtgat
    24001 tggcactgga gccggtggcg gcattgtagc ctataaactg gctcagtccg gtcaagatgt
    24061 tgtagtctta aataccggta agctcccaga gcaaaacata tttgaaaatg agcttacggc
    24121 agagcaaaaa tataattttg gtataggcaa gaacattacc tttccgatta aggatcaagc
    24181 agacttcagc gaagaacttt atgccgatgt tccagacaaa agtacaacaa agattcctcc
    24241 agaagtcttt ctgcactttc aaattcaaca tataaacgga cttcagaacc tctggaatgg
    24301 aatttgcctg cgctattccc aggaagattt tgctaatcgg cataatcata atggaaattg
    24361 tcaatggcaa gtatcttatg aggaaatggc agaccattat agtgcagtgg aaaagcttgc
    24421 cttcgttgtc ggtagtcaag atggactttc acaatttccc gacggcgatt ttatgccacc
    24481 aaagcaactg cgtgacattg atgaactctt cctcagcagc aataaatacc ttgaacaccc
    24541 agagctagtt tttttcaaca accgcaaagc catagaccta cgtgaatatt ccatacagaa
    24601 atgtgtgtct tgtggcagat gttttagcgg ctgtcgctct ggtagtgtat ataggttttc
    24661 gactcactta tatccgcaaa tcaagcagct aaaaaacttc cgtctatttg agtatgcccg
    24721 tgtgattaaa gtggcatcag aaccagggca aaaagctaaa gtgatggcgc tcgacgagcg
    24781 caaccatacg gcagtcgagg tgtatgctga tgtcgtaatt atttcagctg gagctataga
    24841 atccgctcgg ctgcttctca actccttttc catccagtat gcaggtatgg atcaggtagg
    24901 taaatacctt caagatgtcc catccgttgg actaggaacg agtttgatga aaacttggtt
    24961 caaaccagtt tcagcgaaca gaggatatgg agatcatgtt cttgttggcg gtaagctgaa
    25021 agccaaagat acaaaatttc cttttgtagc tcagttttgg tcggatttta tgaaagaccc
    25081 gatttatcta aatgatatta attttctgcc ccgccctttg aaaaaaatag ttgctaaaca
    25141 aatttatcgc agcacagctg ctttaatttt atgggggcct tctgtgccac gaaaggaaaa
    25201 ccgccttgaa ctttcaaatg atctcgatag atatgggcaa agacaactta atgtactcta
    25261 ccaaagagat cccttagagc ttgtgtttaa ccagcaactg gaaaaactag ggcgaaaact
    25321 ccttcgtaat gcttccggct ttgtcgccag ccgcttcgct agccgtccag gtaaaggcat
    25381 ccattactca ggtacctgcc gaatgggggc tacgcccgat caaggtgttg tggataaaaa
    25441 cctgaagttt tatggcgctg acaatattta tatttgtgac gggggtgtga ttccccaact
    25501 tagtgagaaa catccgacat tgacaatcat ggctctggcg catcgcttag gcgaacattt
    25561 aatcaggaaa tactcatgac acacacaaaa atcgcaacca agccatcgag aattgttctt
    25621 ggtacagatt ggatgattgc ttatcccaac tcaagtaagt ggaacatcct gcctgctaac
    25681 aaggcgaata cccttttaga aaaggctgtt agtttaggta ttaatgcttt tgatacagcc
    25741 agagtctacg ctagcgaagg tatccttggt cgatttatca gagctaacaa aattgaccga
    25801 gaaaaggtat ttattatctc caaaggcggt caccctggac tctttttcaa aaatccaaaa
    25861 cccattagta accagcgttt gcaagagcaa ctagagacct cactcaaagc cctcaataca
    25921 gaatatcttg atgtattttt acttcactat gatgatccca gtgttccgac tgacgagata
    25981 gttagatggt gtttaaacct cctggaaact ggcaaaaccc ggcaagtagg ttattctaac
    26041 ttctctctga atcgcctcac agccattacg aaagctttag agtctgaagg tcatattccc
    26101 tgggtaagtg cagagtttaa ttgccttccc gtacaaaatg aaagatggaa gggcgcacaa
    26161 aatatctcgc aaaattttga gtaccttcag tttctcaaag agaagaatat tccattcct
//
