BGC0001080: endophenazine A biosynthetic gene cluster from Streptomyces anulatus
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Location: 1 - 17,804 nt. (total: 17,804 nt).
This entry is originally from NCBI GenBank FN178498.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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Gene details
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General
Compounds
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KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001080
Short description endophenazine A biosynthetic gene cluster from Streptomyces anulatus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other (Phenazine)
Loci NCBI GenBank: FN178498.1
Compounds
  • endophenazine A
  • endophenazine B
Species Streptomyces anulatus [taxonomy]
References
Chemical products information
endophenazine A
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C18H16N2O2
Chemical database entries
NPAtlas
PubCHEM
endophenazine B
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C19H18N2O3
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAX48655.1
  • ppzP
 1 - 900 (+) 5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase (dihydro-PCA prenyltransferase)
  • Tailoring (Prenylation)
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  • CAX48656.1
  • mk
 1009 - 2046 (+) mevalonate kinase
  • Precursor biosynthesis
Sequence-based prediction
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  • CAX48657.1
  • mdpd
 2036 - 3091 (+) diphosphomevalonate decarboxylase
  • Precursor biosynthesis
Sequence-based prediction
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  • CAX48658.1
  • pmk
 3088 - 4203 (+) phosphomevalonate kinase
  • Precursor biosynthesis
Sequence-based prediction
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  • CAX48659.1
  • ippi
 4200 - 5291 (+) type II isopentenyl diphosphate delta isomerase
  • Precursor biosynthesis
Sequence-based prediction
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  • CAX48660.1
  • hmgr
 5288 - 6349 (+) 3-hydroxy-3-methylglutaryl-CoA reductase
  • Precursor biosynthesis
Sequence-based prediction
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  • CAX48661.1
  • hmgs
 6353 - 7528 (+) 3-hydroxy-3-methylglutaryl-CoA synthase
  • Precursor biosynthesis
Sequence-based prediction
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  • CAX48662.1
  • ppzT
 7587 - 8570 (+) 3-oxoacyl-[acyl-carrier-protein] synthase
  • Precursor biosynthesis
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  • CAX48663.1
  • ppzU
 8628 - 9353 (+) Flavodoxin
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  • CAX48664.1
  • ppzV
 9501 - 10121 (-) conserved hypothetical protein ovmZ-like
  • Unknown
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  • CAX48665.1
  • ppzM
 10210 - 11232 (-) phenazine N-methyltransferase
  • Tailoring (Methylation)
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  • CAX48666.1
  • ppzB
 11292 - 11798 (-) Phenazine biosynthesis protein PhzB
  • Scaffold biosynthesis
Sequence-based prediction
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  • CAX48667.1
  • ppzG
 11834 - 12535 (-) FMN-dependent oxidase
  • Scaffold biosynthesis
Sequence-based prediction
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  • CAX48668.1
  • ppzF
 12528 - 13367 (-) trans-2,3-dihydro-3-hydroxyanthranilate isomerase
  • Scaffold biosynthesis
Sequence-based prediction
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  • CAX48669.1
  • ppzE
 13464 - 15404 (-) 2-amino-2-desoxy-isochorismate synthase
  • Scaffold biosynthesis
Sequence-based prediction
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  • CAX48670.1
  • ppzD
 15401 - 16024 (-) 2,3-dihydro-3-hydroxy-anthranilate synthase
  • Scaffold biosynthesis
Sequence-based prediction
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  • CAX48671.1
  • ppzC
 16103 - 17281 (-) 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthase
  • Scaffold biosynthesis
Sequence-based prediction
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  • CAX48672.1
  • ppzA
 17316 - 17804 (-) Phenazine biosynthesis protein PhzA
  • Scaffold biosynthesis
Sequence-based prediction
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: 6BNBMTTKZLI3ZE3JTCJWEZIV, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (MIBiG Annotathon)
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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