LOCUS       BGC0001082             18809 bp    DNA     linear   PLN 17-OCT-2010
DEFINITION  Penicillium paxilli strain PN2013 hypothetical protein PP101,
            hypothetical protein PP102, hypothetical protein PP103, hypothetical
            protein PP104, hypothetical protein PP105, hypothetical protein
            PP106, hypothetical protein PP107, hypothetical protein PP108,
            hypothetical protein PP109, hypothetical protein PP110, hypothetical
            protein PP111, and hypothetical protein PP112 genes, complete cds;
            paxilline biosynthetic gene cluster, complete sequence; and
            hypothetical protein PP121 and hypothetical protein PP122 genes,
            complete cds.
ACCESSION   BGC0001082
VERSION     BGC0001082
KEYWORDS    .
SOURCE      Penicillium paxilli
  ORGANISM  Penicillium paxilli
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Penicillium.
COMMENT     On Oct 17, 2010 this sequence version replaced AF279808.1.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 14:50:51
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 28173
            Orig. end    :: 46982
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(join(1..412,469..795,851..1005,1073..1294))
                     /codon_start=1
                     /gene="paxG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: fung_ggpps"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: fung_ggpps2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 226; E-value:
                     9.3e-69)"
                     /gene_kind="biosynthetic"
                     /note="geranylgeranyl pyrophosphate synthase"
                     /product="PaxG"
                     /protein_id="AAK11531.1"
                     /sec_met_domain="fung_ggpps (E-value: 9.3e-135, bitscore:
                     436.9, seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="fung_ggpps2 (E-value: 6.5e-97, bitscore:
                     312.5, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYILAEALNFVRRGISHLNYWGASHSLSADNYWESNFQGFPRLL
                     SDSSKAPSTIRTVQVLEDDVDDIAIQYNKIVRGPLDYLLAIPGKDIRSKLIDSFNIWLQ
                     LPEEKLSIVKDIINLLHTASLLIDDIQDASRLRRGKPVAHDVYGVAQTINSANYAYYLQ
                     QARLKEIGDPRAFEIFTRSLLDLHLGQGMDLYWRDMVVCPTEEEYTRMVMYKTGGLFNL
                     ALDLMRIQSRKNTDFSKLVELLGVIFQIRDDYMNLQSGLYAEKKGLMEDLTEGKFSYPI
                     IHSIRASPESSELLDILKQRTEDEAVKIRAVKIMESTGSFQYTRETLSRLSAEARGYVK
                     KLETSLGPNPGIHKILDLLEVEYPTNEKGRV"
     subregion       1..18809
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="terpene"
                     /subregion_number="1"
                     /tool="antismash"
     gene            complement(<1..>1294)
                     /gene="paxG"
     mRNA            complement(join(<1..412,469..795,851..1005,1073..>1294))
                     /gene="paxG"
                     /product="PaxG"
     misc_feature    1..18809
                     /note="paxilline biosynthetic gene cluster"
     region          1..18809
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(<1837..>2967)
                     /gene="paxA"
     mRNA            complement(join(<1837..2563,2624..>2967))
                     /gene="paxA"
                     /product="PaxA"
     CDS             complement(join(1837..2563,2624..2967))
                     /codon_start=1
                     /gene="paxA"
                     /product="PaxA"
                     /protein_id="ADO29933.1"
                     /transl_table=11
                     /translation="MTSITTSVLVLHSLLAANFKYYQSFQNGFIDMLSAMADSNSVSGL
                     PGQLCREYTGIRPLDTFLTSCTVFFWPTFQGEIPGLSLYGIAFASAMIPMWLIIVIDVH
                     RRRQPFGALVELIAFAGPLIQCIGPGLVMPLLLARIHTPSRDSKSASQFDYRTFIPSMI
                     IGYILPLLLASLPAPLILSYHNKQQFIAIWQGWPLYSSVLMWAFRRRSGHVHCSRHKGL
                     KHACIFALACSSAGHLVLLSLTWLWSLSYWGYIQSAPWNEPPLASLEAGVLRFLQWDYT
                     LSASATLSWAIAFRHEVVQQKSLRISLLSLLRCLIGIVFLGPCSMVALLYWQTCSLQEE
                     AGQKAPAKDKQLDQEI"
     gene            complement(<3720..>5278)
                     /gene="paxM"
     mRNA            complement(join(<3720..4588,4647..4918,4986..>5278))
                     /gene="paxM"
                     /product="PaxM"
     CDS             complement(join(3720..4588,4647..4918,4986..5278))
                     /codon_start=1
                     /gene="paxM"
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 261.3; E-value: 2.8e-79)"
                     /gene_kind="other"
                     /note="monooxygenase"
                     /product="PaxM"
                     /protein_id="AAK11530.1"
                     /transl_table=11
                     /translation="MEKAEFQVIIVGGSIGGLTLAHCLHRAGIKHVVLEKASDPAPQIG
                     ASIGILPNGARVLDQLQLYDQVEEHIEPLSKATIGLPDGFNFSSSYPKIIDQRFGFPIA
                     FLDRQKMLEILYKGYPDPSKIRLGQRVTSIESLDDGVLITTTTGHVYRGDLLVGADGVH
                     SIVRREIWKARGIARRVSKIKQDSSKLTVEFRCIFGISSAMPGLKLGEQVNALFDGLTI
                     VTIHGKDGRIYWFVIQKLGKKYVYPDSPRYTSHETSIAAEEIRDVKFYENITFGELWDK
                     RETSSMTALEENTFKVWHHGRCVLLGDSVHKMTPNVGQGANMAIEDAAALANLLRKMRI
                     SSGPYFPTSSQMEFLLQKYRDLRYERVNTIYQSSRFLVRFQVRDGIIYSLLSRYWAPYA
                     GDLPADMASKTIADGTMCDFLPTPKRSGGGWEKYSKQGRSWSYLTQLMIYLFGLTIVYT
                     SLTMMFDLEGALKFYFLQV"
     gene            complement(<5758..>6576)
                     /gene="paxB"
     mRNA            complement(join(<5758..5971,6059..>6576))
                     /gene="paxB"
                     /product="PaxB"
     CDS             complement(join(5758..5971,6059..6576))
                     /codon_start=1
                     /gene="paxB"
                     /product="PaxB"
                     /protein_id="ADO29934.1"
                     /transl_table=11
                     /translation="MDGFDVSQAPPEYQAIKPLADLFVVGMGVGWIINYIGMVYISFKH
                     ETYGMSIMPLCCNIAWELVYCLVFPSKSPVERGVFWMGLLINFGVMYAAITFSSREWGH
                     APLVERNISLIFFVATMGFLSGHVALALEIGPALAYSWGAVICQLLLSVGGLSQLLCRG
                     STRGASYTLWASRFLGSTCTVGFAGLRWMYWSEAFGWLNSPLVLWSLVVFLSIDGFYGI
                     CFWYVDRNEKSLGISGPKKAN"
     gene            <7642..>8718
                     /gene="paxC"
     mRNA            join(<7642..7923,7986..8338,8400..>8718)
                     /gene="paxC"
                     /product="PaxC"
     CDS             join(7642..7923,7986..8338,8400..8718)
                     /codon_start=1
                     /gene="paxC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: fung_ggpps2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 93.1; E-value:
                     2.7e-28)"
                     /gene_kind="biosynthetic"
                     /product="PaxC"
                     /protein_id="AAK11529.1"
                     /sec_met_domain="fung_ggpps2 (E-value: 7.8e-113, bitscore:
                     364.7, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVAGSGVLYFLFNNVPSPRFWLKKTQLIGTENPEGITGYECPYE
                     YLRKSYGKHHWAAFVDKLSPNLQNEDPAKYRMVLETMDVIHLCLMMVDDISDGSEYRKG
                     KPAAHKIYGAPETANRAYYRVTQILAQTATEFPRLSPWLMTDLRDILEGQDMSLVWRRD
                     GVNGFPGTASERTAAYKRMVLLKTGGLFRLLGHLTLENNSMDEAFSTLGWHSQLQNDCK
                     NVYSSEYAKMKGVVAEDLLNREMTYPIVLALDASGGHWVEAALKSPSRRNVGNALKIIQ
                     CDYVRDVCMAELARSGAPVKEWLKLWKREEKLDLKA"
     gene            complement(<9258..>11106)
                     /gene="paxP"
     mRNA            complement(join(<9258..9667,9733..10350,10416..10484,
                     10543..10627,10688..10813,10867..>11106))
                     /gene="paxP"
                     /product="PaxP"
     CDS             complement(join(9258..9667,9733..10350,10416..10484,
                     10543..10627,10688..10813,10867..11106))
                     /codon_start=1
                     /gene="paxP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 126.8; E-value: 1.8e-38)"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome P450 monooxygenase"
                     /product="PaxP"
                     /protein_id="AAK11528.1"
                     /sec_met_domain="p450 (E-value: 3e-47, bitscore: 150.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLSDFHISTPLRYFHEEASLLWKLGVFAVLVYFLLPKPTYKTNV
                     KVPTVKYMGPWMPEILSRIFFNSHAPTVIYKGYEKFKTSAFKVVKPDGDLVVLSTRYAE
                     ELRQMPSTTLNALEATFTDHVGGYTTILTDSHLHTETIQKKLTPAIGRLIPRMISELDH
                     AFEVEFPTCDDQFASINPYTVFLRLVARVGARIFIGDELCREEKWLQASIDYTKNIFLT
                     IALMRPMPGFLHPIVGRILPSSRSLKDQLSYIQQDLLGPVIKERRRLEASSDSEYKKPD
                     DFLQWMMDLAQNENESHPDNLSHRLLGITSMAVVHTSAMSMTHILYDLLTMPDLIEPLR
                     DEIRNEIKDWNKATQADLSRLIIMDSFLKESQRLNPPGDLSFHRVVKKDLTLSDGLFLP
                     KGTHICMAAGPISKDPDVVSDPDTFDAFRFVKQRTATSGFVSTGPNNMHFGLGRYACPG
                     RFFAAFVIKLILSRFLMDYDFKFETEHKERPKNLLIGDKIVPNVATPILIKRRATKA"
     gene            complement(<13492..>15578)
                     /gene="paxQ"
     mRNA            complement(join(<13492..13672,13739..13982,14033..14210,
                     14276..14395,14461..14566,14621..14801,14858..15044,
                     15111..15239,15307..15411,15471..>15578))
                     /gene="paxQ"
                     /product="PaxQ"
     CDS             complement(join(13492..13672,13739..13982,14033..14210,
                     14276..14395,14461..14566,14621..14801,14858..15044,
                     15111..15239,15307..15411,15471..15578))
                     /codon_start=1
                     /gene="paxQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 123.6; E-value: 1.8e-37)"
                     /gene_kind="biosynthetic-additional"
                     /note="cytochrome P450 monooxygenase"
                     /product="PaxQ"
                     /protein_id="AAK11527.1"
                     /sec_met_domain="p450 (E-value: 5e-40, bitscore: 126.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFVLSALQRDSWGIAAIILVSIWALHSFHRSRKLQIPVPYVGKC
                     GILGPWISALQWESKARELVQEGYEKHGNFAFKVALLNRWEVCICNEDMIREYKNLMDN
                     QFSAIAVTSELFQIKWTAPGTEEGAHKISIPLLGKALTWQRNRSAAQNDPYFSEFVEEF
                     LYAWKEEVPVPENGDYELPCFETGARVVAHLTARSLVGYPLCRNPEIVNLFTDYGSAVP
                     TSGFFIAMFPEIMKPFVANFCSAPRISKRLQAILLEEFAKRREEGGIESTDIMGWLRNW
                     TDQNEPGVYGDLEITSSIIATIFGAIHTTTQVLVHCLFELATRPEYVEPLRVEIQSALE
                     EHGGWVKEGIEGMVKLDSFIKECQRFNPLDAGSLARRATKDFTFKNGLTIPEGTFVFAP
                     NGPILFDDTLYPEARQFDGYRFYNLGQKTGKPQDFRFAATNQKYLQFGDGRHTCPGRWM
                     ASDEIRLMLAHILMNYDIATKDNKGRPENWIFKKILFPDMKAVVILKARKSVSA"
     gene            complement(<17403..>18809)
                     /gene="paxD"
     mRNA            complement(join(<17403..17550,17641..>18809))
                     /gene="paxD"
                     /product="PaxD"
     CDS             complement(join(17403..17550,17641..18809))
                     /codon_start=1
                     /gene="paxD"
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     dmat"
                     /gene_kind="biosynthetic"
                     /note="aromatic prenyl transferase"
                     /product="PaxD"
                     /protein_id="AAK11526.2"
                     /sec_met_domain="dmat (E-value: 2.5e-99, bitscore: 322.2,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSDELQIPPWESLAEGLGFSNADEEYWWTVFGQPLNKLMDWADY
                     STSEKYRVLAFIHRYVIPTCGPRPKPNGDQYWDTFMGFDHTPIQVSINFYNSKATVRTG
                     NIPISEASGTTEDPINQKASLDTIASQRHLVPGHNLRLFKHFTDAFFIPNEEANILNAE
                     LENRTIAMQAVQCMLSYDFPYRQIQTKVAICPMWKSMQVKRPMGDLMISSIKDLGIDAA
                     DYMKSLKVIEDFINSEKAVQSGAYAIFFAFDTMLTDDYQRTRVKIYFATQSTAFNNMVD
                     IFTLGGRLDGPEMQRATKELRKLWMSTMAIPDGLRDDETLPKSPLPCAGVIFNFEIWPG
                     ADKPNPKIYLPCAYYGKDDLDIADGMDSFFKDQGWSKSFHSYKDNYIKAFVKDGKVMCR
                     HHDISFSYKGQGAYITAYYKPELSEYADPSVWAPKLFKA"
ORIGIN
        1 ttaaactctt cctttctcat tagtagggta ctccacttca agtagatcga gaatcttatg
       61 aattccagga ttgggcccta aggaagtctc cagcttcttt acatagccac gagcctccgc
      121 actaagtcga cttagggtct ccctagtata ttggaagctc cccgtcgact ccatgatctt
      181 cacagcccgg attttgactg cttcgtcctc tgtgcgttgc tttagaatat cgagaagctc
      241 ggagctctct ggagatgcac ggatgctgtg tatgatagga taggagaact tcccctccgt
      301 caaatcttcc atcagccctt ttttctcagc atagagtccg ctctgcagat tcatatagtc
      361 atcacgaatt tggaatataa cacccaatag ctcgacaagt ttagaaaagt cactgtaaaa
      421 tactaattag cattgctgcg aagtgaccgt tatggattag aaacttacgt attcttgcgg
      481 gattggatac gcatcaaatc gagggccagg ttgaaaagac ctccagtttt gtacataacc
      541 atccgggtgt attcctcctc ggtcggacaa accaccatat cacgccaata taggtccatg
      601 ccctggccaa gatgtagatc tagcagtgac cttgtaaata tttcgaaggc gcgggggtct
      661 ccaatctctt tcaatcttgc ttgttggaga tagtaggcat agttggctga gttgatagtt
      721 tgtgctacac cgtatacatc atgagccaca ggctttcctc tccggagccg tgatgcatct
      781 tgaatatcat cgatactata atcaccatga tgttagaata gaacaggagc gctggggttg
      841 gaaatctcac agaagggatg cagtgtgaag taagtttatt atatctttca caatagacaa
      901 cttctcctct ggaagctgga gccatatgtt gaaggagtcg atcagcttgc ttcggatgtc
      961 ttttcccgga atcgctagaa gatagtctag aggtccacga acaatctaag aagaacaaac
     1021 gattggtata atgaaacaca aggggaatcc caagagcaat gacagaactg accttgttat
     1081 actgaatagc aatatcgtca acgtcatctt ctagcacctg cactgttcta atcgtgcttg
     1141 gtgctttgct ggaatcactc aggagtcttg ggaatccttg gaagtttgat tcccagtaat
     1201 tatcagcaga taatgagtgt gaagctcccc aataattaag atgagatatt cctcgacgaa
     1261 cgaagttcag agcttctgca aggatgtagg acatggcgtc gaacttgatg aagttttctc
     1321 tggcgtgaac ctgaattcaa gagcactatt tttataaccc tatgatgaaa gaaatgggac
     1381 tggaagaaat tcttttctat tttgcagagt aggattgcaa aattgcgatg aaggaaattc
     1441 cggggtatgg gtagggttcg agagtaaacg acaccggatc cttgtattga tttatgccgc
     1501 taaaaatccg ttcccaacta ccccagttaa ataactctct ataattacaa ctgcggtaca
     1561 gtcatgtttc aaattctcga aaataaatcc ctctgccccc acttgagaac tccgtattat
     1621 agacaaggcg tgcgaacatg gatgacatga tgcaacgatt atggttgcgt tgtaatacat
     1681 ccatgactgg gtgattcgta ttcacaaagc gagatgtaat tctgtgtacg gaagtaaact
     1741 ccatagatta tacgtgccag atctcgtgca tagtattcaa cacaacaccc agtaagtttt
     1801 aaaattgata accttgacta gtcacaggtc gtgaatctag atctcctggt ccagttgttt
     1861 atctttagcc ggcgcttttt gcccagcttc ctcctgcagt gagcatgttt gccaatacaa
     1921 caaggccacc atgctgcatg gcccaagaaa aacgatccca attaggcaac gaaggagtga
     1981 gagtaacgaa atgcggaggg acttttgttg aactacttcg tgtcggaaag caatcgccca
     2041 gctcaacgtg gctgaagccg ataacgtgta gtcccactga aggaagcgga gtacgccagc
     2101 ttctagactg gccaatggag gttcgttcca tggggcagat tgaatgtaac cccaatagga
     2161 caaactccag agccaagtca atgacagaag aaccaggtgg cctgcagatg agcaagccaa
     2221 ggcaaatatg catgcatgct ttagcccctt atggcgcgaa caatgtacgt ggcccgagcg
     2281 gcgacggaag gcccacatga gaacggaact gtacaggggc catccttgcc agatcgcaat
     2341 aaattgctgc ttattatgat acgaaaggat aagtggagct gggagtgagg cgagaagtaa
     2401 aggtaagatg tatccgatga tcattgaggg gatgaatgtg cgataatcga attgagaagc
     2461 tgatttgctg tcgcgacttg gtgtatgaat ccttgctaag agaagtggca ttacaaggcc
     2521 cggtccaata cattgaatca aaggtccggc aaaagctatg agcctatcga agcgattcct
     2581 gtcagcttgg gtcgctatac cgatgatctg cacgcgggct tactccacca aggcgccaaa
     2641 cggctgacgg cgccgatgta catcgatcac gattatcaac cacatcggaa tcatggcact
     2701 agcgaaagcg attccataaa gggacaatcc gggaatctca ccctgaaagg ttggccagaa
     2761 gaatacagta cagcttgtca agaatgtatc aaggggcctt attcctgtat actcgcggca
     2821 gagttgtccg ggaagtcccg aaacggaatt gctgtcggcc attgctgata acatgtcgat
     2881 gaagccattt tgaaaggatt ggtaatactt gaagtttgcc gcaagtagcg agtgtaaaac
     2941 aagaacactc gtggtgatgg atgtcatttt ggcttacttc agtttaactg ttttgctaat
     3001 tggccgattt ccgagaatag agttgcaaaa caatgggcat ctgatacaat agcctggtga
     3061 gatctccctt cttaaatccc cgatagaatg aaacatggcc caaaaagacg aggaattata
     3121 gctaggagga aattggatct ttcatcggtg taactgacat ccattacagc tgacgaaatt
     3181 accaagttcg ctggctggtc tcgattgctt gtgggtctac ggccacccag gtaattcttc
     3241 tgtcgtagag gtggattagg acttgcatta tgatactaac cttggaacat tgcttatata
     3301 ttatgagaca ctgtccggcc ttgatttgcc acatttaata tagaatttcg ttttcggagt
     3361 tgacccagtg tagtagaagg tggtgaagga atgtcgattg tcaatttcga aagttctatc
     3421 ttccatcgta ctggtcagtc agagtacccc tctgcagtag aaatatttcg tagaaaaagt
     3481 aggtatggat agtgtatgga attttcatag tatggcttac tcaagctgtg agtattcgct
     3541 gcccatttga gatcgcttga atgctctcgc agggagcctg aagacggttt aaaacaaagc
     3601 ggcttaacga tatagtacta attgaactca aatctagtga tgtttcttga aagcaagata
     3661 ggtgacaatc aacagctaga cactggaaag aaaggaaaac caaaaattgc tccaatggtt
     3721 taaacttgaa gaaaataaaa cttcagggca ccctcgaggt cgaacatcat tgtaagagag
     3781 gtatagacaa tggttagtcc aaatagatag atcataagtt gagtcaaata actccagctt
     3841 cgcccctgtt tgctatactt ctcccatcca ccaccacttc gctttggcgt agggaggaaa
     3901 tcacacattg tgccatcagc aatcgttttt gacgccatat cagcaggcag gtcaccagcg
     3961 tatggtgccc aataccggct tagcaggcta tagattatgc catcacgaac ctgaaaacga
     4021 accaagaatc gagagctctg gtagatagta ttgacgcgct catatcgaag gtcgcgatat
     4081 ttttgcaaaa ggaactccat ttgtgaggag gtgggaaagt atggtccaga ggaaatccgc
     4141 atctttcgaa ggagatttgc cagagcagcg gcatcctcaa tggccatatt agccccttga
     4201 ccaacattgg gagtcatttt gtggacactg tctcctaaga gcacgcagcg gccatggtgc
     4261 cagactttga atgtattttc ttccagagca gtcattgaag atgtctctct tttgtcccag
     4321 agctcgccaa aagtaatgtt ttcgtaaaac ttgacatccc tgatctcttc tgccgcaata
     4381 gatgtttcat gggacgtgta gcgggggctg tcaggataca cgtatttctt gcccagcttt
     4441 tgaatgacga accaatatat gcgaccgtct tttccatgga ttgtgacaat agtgagacca
     4501 tcgaataaag cgttgacttg ctcgccaagt tttaatcccg gcatcgccga tgaaatgccg
     4561 aaaatacagc gaaactcgac cgtaagctct tcgtacttgt tagcatgaat gcaaagacat
     4621 gaggcctgtt gatgctatcc actcactgga actatcttgt ttgatctttg atacccgtct
     4681 ggcaattccc cttgccttcc atatctctct gcggacgatg ctgtggactc catctgcgcc
     4741 gacaagaaga tccccacgat aaacgtgtcc agttgtggtg gtaattagca ctccatcatc
     4801 caatgattca attgatgtaa ctctttggcc cagacgtatt ttgctgggat ctggataccc
     4861 tttgtagaga atttcgagca tcttctgtcg atctagaaac gctataggaa aaccgaacct
     4921 gttgcctcac gggtgccatt ttagatgata atgcaaaact gtataagatc aagataatta
     4981 ctgacctttg atcgatgatc tttggatatg agctgctgaa gttgaaccca tcaggaagcc
     5041 caattgtagc tttgcttagc ggttcgatat gctcttcaac ttgatcatag agctgaagct
     5101 gatccagcac gcgagctcca ttcggcagaa tgccgatgga tgctccaatc tgtggtgctg
     5161 gatcgctggc cttttccagg acaacatgtt ttattcccgc acgatgtaga caatgtgcca
     5221 atgtcaatcc tccgatcgac ccgcccacaa tgataacttg aaactcggcc ttttccatgg
     5281 tttctgaatc ttaaagatac atgaaaagaa taaagcaaaa ggtgaaatat gaataaggtt
     5341 aacaatgagg aacgatgaac agtggttgaa attcaaactc agaatcaacc tttgcatact
     5401 aatatcatat gatacagatt gcatagtgtc agccacaaat gatcattgct tactactaaa
     5461 acgtgccaat tatatcatgg attgggtcgc cttggacatg cacgttacgc gtatcgtaag
     5521 caaagtacat cgtatgtact tttcttcaat ttcaatctag cactggcaga aatgcatgaa
     5581 gaaaagattt cttttttcgg atcttagttt ccaaggttat ttcaaaaagt aaacgtgtat
     5641 ttttgtttct aattttcttt tcttttcttc aatttcattt tactttttct catccctcca
     5701 tagataatgc attgtatgca gaataagcta gttacatgtt tcaccctcaa ctgccgatca
     5761 atttgctttt ttcggcccgc ttatgccaag tgacttttcg ttacggtcga cgtaccagaa
     5821 acaaattcca taaaacccat cgattgataa aaacaccaca agactccaca gtaccaaagg
     5881 actattcagc caaccgaatg cttccgacca atacatccaa cgtaagccgg caaacccaac
     5941 tgtacatgtt gatcctaaga agcgggaagc cctatagtac agaagatgag tacttgtatt
     6001 tctgtcactt tggggaagaa attccgattc atcgggcatg aaatgagatc agacatacca
     6061 tagagtatag gatgcgccac gcgtactgcc tcgacacaac agttgactca atccaccaac
     6121 gcttagaaga agttgacaaa tgacggcccc ccatgaatat gccagcgcag gcccgatttc
     6181 aagggccaat gcaacatgcc cagagagaaa gcccatggtc gcgacgaaaa atatcaagga
     6241 aatattgcgc tcaacaagcg gcgcatggcc ccactctcgg gatgaaaacg ttattgctgc
     6301 gtacatgaca ccaaagttga tgaggaggcc catccagaat acacccctct ccaccgggct
     6361 tttcgaggga aagaccagac agtagaccag ttcccacgcg atgttgcaac agaggggcat
     6421 aatcgacatt ccgtaagttt catgtttgaa cgagatgtag accattccga tgtagtttat
     6481 gatccatcct actcccatgc caacaacaaa aagatcagcc aatggcttaa tcgcctggta
     6541 ctccggagga gcttgggaaa catcaaaacc gtccatagtt tctaaggttg acgtgggaaa
     6601 aagaaattag agtcactcgt tgaatagcta tagattgaag gatttgacca tgatgcgtat
     6661 taacggctaa atgtacgtct atttatgccc tgtggatgaa atgggaatat tgaattgtta
     6721 atgaaactgc attatctcat cggttagccc gcagcgggag atggacactc ccggaaatct
     6781 ctgtagatgc agtccacgag gagatcctgc aagatctaaa ctagtctatt tcgccaacga
     6841 aagctagtat gcagtcattc ttgccatgga attcagacga actgcgtcgc aacaattagc
     6901 tgtctttgga taggcagagt ttaggcttac tgccaagtga agaaaatggc tcaaaggaat
     6961 gaaagccgat ttgagtacgg tgcgcctgga aaatcgaggc gtcgatgtgg atcagggcaa
     7021 aagtttcgtt actttccctc ttttttaatt aatattataa ttcttatttt tctcactgca
     7081 tgaaggatct tgaggcgttg ctgcgcttaa cctatttagg cgtgatgttg tcattacagg
     7141 ggctggtatg aagaaaaaat aaaagattaa ttactactgc atagtttgat atctgcatca
     7201 cggagaaacc ggaattatta aggtaccgac agcccctctt gatactacta cctcgttgct
     7261 catcgtagac atcgctgaat gaggtcaatc cgtaaattta gtaacatgta tcacttttgg
     7321 gatcacgcct gaaagctgac aattgtgggg cgaaaatgct gaacgcgatg aatcccactg
     7381 ctttttctaa ttgtgatagc tgcagccgcc gattggacac ctgggaaagt atactccttg
     7441 cattacttat tatatggagg ggatgtattg cgccgaatct caacagccta ccaagcagag
     7501 ctactcgact catttcattt ttcctttcct tgagagaact cgagaatacg ttagtcaata
     7561 ccaaattctc tgttccaagt caacatgaat actctttcga ttctctccaa cacagccttt
     7621 cagggtgtag gtcccatttt gatgggcgta gcagggagcg gagttcttta ctttcttttc
     7681 aacaatgtcc cgagtcctcg cttctggttg aagaaaaccc agttgatagg aaccgagaac
     7741 ccagaaggca taactggcta cgaatgccct tatgaatatc tgcggaagtc atacggcaag
     7801 catcactggg cagcgttcgt tgacaagcta tcgcccaacc ttcaaaatga ggatccagct
     7861 aaataccgca tggtgcttga aacaatggat gtcattcacc tatgcttgat gatggtcgac
     7921 gatgtaagat catttgccat tatatagagg ctttattatc attgtatcta acttctgatt
     7981 cctagatctc cgatggaagc gaatatcgca aaggaaagcc ggctgcgcac aaaatttatg
     8041 gtgcgcctga aacagcgaat cgggcttatt atcgagttac acaaatattg gctcaaactg
     8101 cgacagaatt cccacgtctt tcgccttggt tgatgactga tcttcgggat attctcgagg
     8161 gtcaagatat gtcccttgtc tggcgccgag acggagtcaa tgggttccct ggaactgcat
     8221 cggagagaac tgctgcttac aagcgcatgg ttctgctaaa gacaggtgga ctatttcgtc
     8281 tactcgggca tctcactctc gagaacaatt ccatggatga agcctttagc acccttgggt
     8341 aagaaagaaa aatattttcg gcagccttct gaattttgct aatatttaat gattcctagc
     8401 tggcattcgc aattgcaaaa tgactgcaag aatgtctact cgtcggaata tgccaagatg
     8461 aagggcgttg tagcagaaga tttgctcaat cgtgagatga cataccccat cgtactcgca
     8521 ctggacgcct ctggtggtca ttgggtagag gcagctctaa agtcgccctc tcggcgaaac
     8581 gtcggaaatg ccttgaagat aatacagtgc gactatgttc gagatgtttg catggcagag
     8641 ctggcgagat ctggtgcccc ggttaaggaa tggttgaagt tatggaaacg ggaggagaag
     8701 cttgacctga aggcatgatt ggccttgtga aatatgggac tacgaagtga atcagaagtg
     8761 aatattgagt atttgagtct agatagttca caattttact tgcaattacc aaactttgca
     8821 gaattctacc aagctagact acatgcgggg tgtatccttc ttagactcat gtctgcagtt
     8881 cagtatacaa cgaggatgcc ttctatagga tattgaatct acgttgaagt attccttata
     8941 gaggttgcaa agtgcccagc aacatctgat atccgacatg acagagatga gcatggatta
     9001 caattttgcg agggcggcca ttcaatctca aggcaatgtc cctttacaga agaaccagaa
     9061 aaggatgcca acaaggttaa tgcactcagg tattctgatc cgactcactg ttacagagaa
     9121 tagaagacat tcctgaggat taataaacag aaagcataat tcaattcatt ctaagatgta
     9181 aaatctatct ccagtgaacg tccactgccc accactgcgt tcaaagacaa cgaaagcgac
     9241 cggcaacgta tccctattta cgcctttgta gcccgacgct tgatgaggat gggcgttgcg
     9301 acattcggta cgatcttgtc tccgatcaat agattcttcg gtctctcctt gtgctcggtc
     9361 tcaaacttga agtcatagtc catgaggaac cggctgagaa tcaacttaat cacgaacgct
     9421 gcgaaaaacc ttccagggca ggcataccta ccaaggccga aatgcatatt gttgggacct
     9481 gtgctgacga aacccgacgt tgcagttctt tgcttgacga agcggaatgc atcgaaagtg
     9541 tcagggtcac tgacgacatc gggatccttc gagatgggac cggcggccat gcagatatga
     9601 gtgcccttcg gaaggaagag cccatccgat agagtcaaat ctttcttgac aactcggtga
     9661 aaagatactg ggttttcatc cgtaagctat tatcattcag aaaaggctga tatggatttt
     9721 tcgttcactc acgatctccc ggggggttga gtctctgcga ctctttcaga aagctgtcca
     9781 taataatgag tctgctgaga tcggcctgag tggccttgtt ccagtccttg atttcatttc
     9841 gaatctcatc acgcaatggt tcgatcaaat caggcattgt aagaaggtca taaaggatat
     9901 gggtcatgct catggcactg gtgtgcacga ctgccatact tgttataccc aacaagcgat
     9961 ggctaagatt gtcaggatgc gactcgttct cattttgggc taggtccatc atccactgga
    10021 ggaagtcatc aggcttcttg tattcggagt ccgagcttgc ctcgagcctt cttcgctctt
    10081 tgatgaccgg accaaggaga tcttgttgga tgtaggatag ctggtccttc aagcttctgc
    10141 tggaaggcag aatccttcca acaatcggat gaagaaatcc tggcatggga cgcatcagtg
    10201 caatcgtcag gaagatgttc ttcgtgtaat cgatggatgc ctggagccac ttttcctcgc
    10261 ggcaaagctc atcgccgatg aaaattcgag ccccaactcg agcgacaaga cggaggaaca
    10321 cagtgtaagg gtttatggaa gcgaattgat ctgtccatag tgatttagta accttaaaat
    10381 atgggaaagt ctcgctggta cgaggctcca cctaccatcg catgtaggga actcaacttc
    10441 aaatgcatga tcaagttcgg aaatcattct ggggataagt ctccctggat gaggtgtcag
    10501 tacatcaacc aatcatgtat tggaagaaat gtcgatcatt accaatagcg ggcgttaact
    10561 tcttttgaat tgtctcagtg tgcagatggc tgtcggtgag aattgtggta tacccaccaa
    10621 cgtggtccta attcccacca taagttcaat tgaaatgtca tggaatttag aatggaaggc
    10681 tttttaccgt gaatgttgct tcaagtgcat tcagggttgt tgacggcatc tgtcgcagct
    10741 cttccgcgta tcttgttgag agaaccacaa gatcaccatc aggcttcacc accttgaagg
    10801 cagatgtttt gaactatatc agtgttaatt tcaatcattc atcccgactg ttaggagatg
    10861 tttaaccttt tcatagccct tataaatcac tgttggagca tgtgagttga agaaaattcg
    10921 actgagaatt tccggcatcc aaggacccat gtacttgaca gtaggaacct tgacattggt
    10981 cttgtaggtg ggctttggta aaagaaaata gacaagtaca gcaaatactc caagcttcca
    11041 aaggagactt gcctcttcgt ggaagtaccg aagaggtgtt gagatgtgga aatcggatag
    11101 atccatcttc tttaggtagt tttagttaaa tcgaggaaag agatatccaa tgtcaacgtg
    11161 acagctgtgt cccttgaagt tcccaagagg cctttaagat caaatttgat gaaggacaga
    11221 ttagttcagt gggtttgtta tgggcgccgt gggcatcctg gtataaaata aaaataacat
    11281 gaggccgtca tggtactaat gatacaagtt aggcgttgtg gaactagact atcggaaaca
    11341 tgtactatgt aagataacac tccaacttct tcataccgaa tattacagca cagtatacct
    11401 actagtaccc tgtcttgaga ttcatctaag tacagggtct tggaattgcg tgcttctcgt
    11461 aacgcctaga agctccactc caacttggta aagtaccctt acgaaatctt ctcttccaaa
    11521 ggttcaggcc cccttgtaag caatcaaata cagctaaatt ctgcgaatta ctttcccgaa
    11581 ttattggaac tacatagaaa tggtagcaag attcgtcttc cttccgcggg ttgcccaagg
    11641 cagtttacat gatgtcggtt aaactcaatt tcggctgctt accatgcata atgctgcaga
    11701 aatcctgaag cattgagggt caaatatcag atttgactat caggtttacg gaatgatgac
    11761 gataattcca ttttgagggg aagtacattg gtttttcacg taggaccgtg tgtgagcacg
    11821 gtggcactag ttatctgtcc ccgcatcctg ccaatgtata gagctttgga aggttgcagc
    11881 gtgtaacaaa ggttccgagg taaaaggcct cggctggcct actacctaaa gtaccagact
    11941 acttactaag tagcaaatgc ttcacggtta cctactatat acaggctctc tgctatacca
    12001 cttaggctgc gctcaaaact tagtatgctc agcttggttc ccctctgcgc ttgttgagtg
    12061 tgctagcagc aaatctttct tggtagtaga tgatgctgga attaattgca tggatatcac
    12121 ttctatttct catactttct cagagactac tacaataaaa attgaaaacc ctatctctag
    12181 gtactacact agtctaatgg ttgaaagtct atactactgg ctggggcatt tagtgagatc
    12241 aaatctttca cccgtttgaa acctggaaga aaaatagaat aaatcgaaat aggagccaca
    12301 gttcgaagtt cccactggca caactctggg attcgccggg aaggcctgct gccagtggga
    12361 gggtctgagt tgagttccca cgcatttggt aatgggttat actagtacct accaacaagt
    12421 aatatatgat tcgaaggttt gaatacggtg gagtactcct agtgttccga gtatcgtggt
    12481 aaacttaact aggtagttcg tcaagttgtg agtgttattt ctttactcgt cccaataatc
    12541 cacaattatc atcgacgcct aattgattag gacccccagg catagaaatg cagtcatcaa
    12601 atccacaaaa tatccaattc aaggtatagg aaatgggggc tgtaagatcg tgtctagaag
    12661 attcctcatc atcttggtat acatacaccc ggggctgaca ccaagtaata atctacaggg
    12721 gaagtcttgg gtggggtaag aggataggaa aacttggaag aaattcaatt ttaggaagat
    12781 tactgcgtac tgaaggggaa tatacccatt tctcgcttat aatggcactc atgcaagtcc
    12841 tgcaagacaa aagtccagta atcgtaacca aggccaacca caagacggag agaatctttc
    12901 gcccccacac cgcgcaaaag ctgggccatc atcaattcac tctattctca ccacctccgc
    12961 tataaggcga actgctccgc tatgtgggaa cggtctagtt tcaaattcgc tgggttggag
    13021 taatcatttt aacaattgat gaaagcccaa tcgcaagtcc tacagctcat tatcgtgcaa
    13081 gcagctggct caccccacct ctggggttgt agtggcgaac tatgtgagac taaggagccc
    13141 cgatcctgct agtgtttaac ctgccccatt tttcatgccc actttcacat cttgccttat
    13201 tgtggcgcag tctagagttg caaactttga gatacttggt aagcgagcag gagagatacc
    13261 atgcgcctca gatactgttt catttcattg atagtagtag agttagctag actggcgagt
    13321 cttcttctgg aactacagga tagtccagat tctgagtagt aacaaacaat aagctcgtag
    13381 tagtacatgt tgagaaagcc ttgaaatttt gatactatgg ttgcttgaat aaggcgatcc
    13441 gattccacgg atgtcaaatt tatcgagtgt aatctatttc caaatttccc ttcatgccga
    13501 gacagacttt ctggctttca aaataaccac agctttcatg tcaggaaaca atatcttctt
    13561 gaagatccaa ttttctggac ggcccttgtt atctttagtt gcaatgtcat agttcattag
    13621 aatatgcgcg agcattagac ggatttcgtc agaagccatc catcgccctg gactaaagac
    13681 gggacgggga attagtacca acttcgattt tgttcttgat aaacaaagac caactcacca
    13741 cgtatgcctg ccatctccaa attgtagata tttctggttt gttgctgcga accggaagtc
    13801 ttgtggtttg ccagtctttt gacctaggtt ataaaatctg tatccgtcga actgacgtgc
    13861 ctccgggtag agcgtatcgt caaacaaaat tgggccgttg ggcgcaaaca cgaaagttcc
    13921 ttcaggaata gtcaatccat tcttgaaggt gaagtccttt gtggcacgac gagccagtga
    13981 gcctggatag ttcagcaaat ttcttacacg cccacgacat ctggataatt accggcgtcc
    14041 aatgggttaa atcgttgaca ctctttgatg aagctgtcaa gttttaccat cccctcaatt
    14101 ccttccttaa cccaccctcc atgctcttcg agcgcagact gaatctcaac cctcagaggc
    14161 tcgacatact caggtctcgt cgctagctca aataaacaat gaacaagaac ctgccatctg
    14221 ttagaataaa aaagcgttca atctgcaaag ctacctgctt gaatttaggt attacctggg
    14281 tcgtggtatg aattgctccg aatatcgtgg caatgattga ggaagtgatc tctaaatcgc
    14341 catatacccc cggttcgttt tggtcggtcc aatttctcaa ccatcccatt atatcctgca
    14401 ttgaggtact cttcagacaa acttcaatta aattaacatt caagttaagc aagaacatac
    14461 cgtagattca ataccacctt cttcccgccg tttggcaaat tcctccaaca ggattgcctg
    14521 caaccgtttc gagattcttg gagcgctgca aaaatttgca acaaagctag atagaaatat
    14581 atcagctcag tcgtatgcag taatgaagat agaaacaaac ggtttcatga tctcaggaaa
    14641 catcgctatg aaaaatccac tcgttggcac agcgcttccg tagtcggtga agaggttgac
    14701 aatctcaggg ttacggcaca atggatatcc taccagtgac ctggcggtaa gatgtgcgac
    14761 aactcttgca ccggtctcaa agcaaggcag ctcataatct cctattgaag tattcagttt
    14821 gccgtgtctt tctatcttat tgtgtgggta accttaccat tttcaggaac tggaacttct
    14881 tctttccacg catacaggaa ttcttctaca aattcactga agtacggatc attttgcgca
    14941 gcagatctgt ttcgctgcca ggtcagagct tttcccaata gtgggattga aattttatga
    15001 gccccttctt ctgttccggg tgctgtccat ttgatttgaa ataactattc aattagaagc
    15061 aaacgatgga attgttagtg tggatcacta tggtctgaat attcactcac ttccgaagtc
    15121 actgcgatgg cagaaaattg attgtccatg agatttttgt actctctgat catgtcctcg
    15181 ttgcagatgc agacttccca gcggttgagt aacgcaactt tgaatgcaaa gttgccatgc
    15241 tagatttgaa taagttgcaa aaaccgttag agctggaata gtacttgcat ctatgtctgg
    15301 acataccttt tcatatcctt cttgaaccaa ctcccgtgct ttactctccc attgtaatgc
    15361 cgatatccat ggtcccaata tgccacattt tccaacatag ggcacgggga tcaacacaaa
    15421 tgttagaacc agctcatgtt cgcaaatgga gttagacttc agttaattac ctgcaacttt
    15481 cgagaccgat gaaaggagtg cagagcccag atagagacta gtatgattgc ggcaataccc
    15541 cacgaatctc tctgtaaggc tgataacacg aaatccatac ttgcgataga ttctaacgaa
    15601 ggggtcactt ttgtgttcca aggccctaga gggcataggg tgtatttttc aatgggagtt
    15661 tcggtcacac aacaacacca aaatgaacgc ctgaagacga cttagtatga ggaactacca
    15721 gtgttaggac ttttcgcttt gcttacagag gacgcctcgt agtagaacaa agagagctac
    15781 tcgttgatta tttgatgaga ttttattggt cgcctgcaga attccggatt gtggatcctc
    15841 aacagctgac aacatggatc ttgcatgaag aggggtacct acagggagct gcataaaata
    15901 aaaagccaca aaatgaatcc accctgcaaa agccgattgg atgaataaag agtgactgaa
    15961 atggatctgc gggccatgag gcggccaagt tttgatttca gggatccaat cacgaggttg
    16021 atgacaaaat tgccattttg agaaactgat gcggtgataa caaatttttc tttcaggtat
    16081 ccccttgagt gcatttttgt cctttaggtg catctggtgg cgaagtaaat ggtatcttgg
    16141 cagtcatcac agctgattta tccacaatga ctttgtacgg taaggcatga agcggagtgt
    16201 gtcagagtat tcacccaggt tgaatcatcc ttcgagatgt caggtaggca tcttacttga
    16261 tgtgagtttt ccctattacc gtcactgcag tgtggctctg gagcgaacgc caaggtgggt
    16321 gtctgcaatg gctaacgcac agtggtttcg gcactccgac attgggaatg atagagagat
    16381 cattcagggt ttgacccttt ggatctcctt tggtcccctt aaatgatagt aagaacctgc
    16441 tctccggtat tgtacgtaac ggatggacct ttgaaaactc accccctccc ctggggtcct
    16501 cggagactcg gaggcaaagg agagatagca aggattgtgg tacgttcagc tcatgactgc
    16561 aagcaacgag aaattcggca caggcctcaa tctccagcca aaaaaatcgt cggaaacgtt
    16621 ttagtgaact gttgggtatc taatatgaga tccttgttgt attggccact gcaatgtgca
    16681 tgtgcactga catataacga gttcgagtgg agtttgactt cttttgctct tcatttcacg
    16741 ataatactaa tatgagggaa tagtacattt gataccacta cgtgcaatta ttgattcatc
    16801 tgttctcaag ttcgcctggt actaaggagt tcctggcact atttactaca ttattaaatc
    16861 agcccatatt tcaagtttag atcttgaatt cttgaagttg gtcctggatg atcgttcggg
    16921 ccttttgaac tgtttatgcc gtttccagta ttactatatc cattccttgg tccatgtttc
    16981 gtggctagtg cctactacta ggtagtacca ggaactcaag gttctttcaa agcaaccgct
    17041 gtttcaactt ttcctcctat tatgaagact agaaactggt catggtgcgt aggccatcca
    17101 tggataacgc tactataatt ttcggtatgt ttcaagttct ttccctgctt tcgatcccgg
    17161 cggtacaatt ggatatttac aatgctcacg cgttcaattt acgtcaggct gccttcaagt
    17221 tccgcttgca attgtgatat gatttgaaag tatccaattt gagcagtagt ccaaagacta
    17281 agatatcatt tcaatattgc tcgacgccaa ccaaaggcca gatctatcct agagaccact
    17341 tcaattgtac tagttgggca ctagtatctc gttgctccag ctactgctac cagcatgatt
    17401 gactatgcct tgaaaagctt aggagcccat acagaaggat cggcatattc agaaagctct
    17461 ggcttgtagt aggccgtaat gtaagcgccc tgccccttgt atgagaaaga gatatcgtga
    17521 tgacgacaca ttactttacc gtccttgacg cttcatatgt caattttcat tagcatccga
    17581 cttccatccc aacttgaacc aagattgata atagtagagg gtgaagtggg aaacactcac
    17641 aatgccttga tgtagttgtc cttataagaa tggaaggatt tactccatcc ttgatctttg
    17701 aaaaaagagt ccatgccatc tgcaatgtcc agatcatctt ttccataata cgcacatgga
    17761 agatagatct tggggttggg cttatcggca cctggccaaa tttcaaaatt aaagattaca
    17821 cctgcacatg gcaaagggct ctttggaaga gtttcatcat cacgtagacc atctgggata
    17881 gccatagtgg acatccacag tttccggagc tctttagttg ctcgttgcat ttcggggcca
    17941 tctagccgcc ctccaagagt gaagatatca accatgttat tgaaggctgt ggattgtgtt
    18001 gcgaagtaaa tcttgacacg agttctttga taatcatcgg tcaacatagt gtcgaaagca
    18061 aagaagatgg cataagctcc agactgaacg gccttctcgg aattgataaa gtcctctatc
    18121 actttgaggg acttcatata atccgctgca tcaattccca agtctttgat tgaggagatc
    18181 atgaggtcgc ccatgggacg cttcacttgc atggatttcc acattggaca aattgcaact
    18241 ttggtctgaa tttgacggta tgggaagtca tagctcagca tgcactggac agcttgcatt
    18301 gctatggtcc tgttttctaa ctcggcattg agaatgtttg cttcttcatt aggtatgaag
    18361 aatgcatcag tgaagtgctt gaagaggcgc aaattgtgtc ctggtacaag atgcctttga
    18421 cttgcaattg tatccaaaga agccttttga ttgatgggat cctcagtagt tcccgaggct
    18481 tcagaaattg gaatgtttcc cgttcgaaca gtggctttgc tgttgtagaa gttgatactg
    18541 acttggatcg gggtgtggtc aaaacccatg aatgtatccc aatactgatc gccatttggc
    18601 ttcggcctgg gaccacatgt gggtatgaca tagcgatgga taaatgccag tactcggtat
    18661 ttctcagatg tactatagtc tgcccagtcc atcagcttgt tcagaggctg accaaagaca
    18721 gtccaccagt attcctcatc ggcattgctg aacccaaggc cctcggcgag cgattcccag
    18781 ggtgggattt gcaactcatc gctttgcat
//
