BGC0001084 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001084 (Aspergillus sp. MF297-2)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS,indole	1	40,738	notoamide A	NRPS:Type I+terpene:Hemiterpene+other:other	100%

BGC0001084 - Region 1 - NRPS,indole

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Location: 1 - 40,738 nt. (total: 40,738 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
indole: (indsynth or dmat or indole_PTase)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 40,739
Label		BGC0001084

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001084	1.72	NRP, Terpene, Alkaloid	notoamide A	Aspergillus sp. MF297-2
BGC0000818	1.10	NRP	notoamide A	Aspergillus versicolor
BGC0002254	0.80	Polyketide	notoamide F, (+)-semivioxanthin, waikikiamide B, waikikiamide C, notoamide A, waikikiamide A	Aspergillus sp. FM242
BGC0002157	0.69	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0001249	0.68	NRP	dimethylcoprogen	Alternaria alternata
BGC0002226	0.67	NRP	acu-dioxomorpholine B, acu-dioxomorpholine A	Aspergillus aculeatus ATCC 16872
BGC0002391	0.66	Terpene	zealexin B2, zealexin C2	Zea mays
BGC0000687	0.66	Terpene	phyllocladan-16α-ol	Diaporthe amygdali
BGC0000900	0.65	Other	ferrichrome	Aspergillus oryzae
BGC0001893	0.64	Other	abscisic acid	Botrytis cinerea B05.10

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001084	1.00	NRP, Terpene, Alkaloid	notoamide A	Aspergillus sp. MF297-2
BGC0000818	0.73	NRP	notoamide A	Aspergillus versicolor
BGC0002157	0.68	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0001249	0.67	NRP	dimethylcoprogen	Alternaria alternata
BGC0002226	0.67	NRP	acu-dioxomorpholine B, acu-dioxomorpholine A	Aspergillus aculeatus ATCC 16872
BGC0002391	0.66	Terpene	zealexin B2, zealexin C2	Zea mays
BGC0000687	0.66	Terpene	phyllocladan-16α-ol	Diaporthe amygdali
BGC0000900	0.66	Other	ferrichrome	Aspergillus oryzae
BGC0001893	0.65	Other	abscisic acid	Botrytis cinerea B05.10
BGC0002736	0.65	Terpene	preaspterpenacid I	Aspergillus terreus NIH2624

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 36217:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Pro - Trp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ADM34138.1

Search NORINE for peptide: strict or relaxed

AMP-binding (84..484): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVMMIGAVNK
Nearest Stachelhaus code(s):: Pro DVMMIGAVNK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1165..1564): Trp

nrpys: Trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVYFVGGICK
Nearest Stachelhaus code(s):: Trp DVYFVGGICK (100% 8Å match); Trp or Pro DVYFVGGICK (94% 8Å match)
Stachelhaus code match:: 100% (strong)