Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001093.1:
Cluster 1NRP / Polyketide184868

BGC0001093, disorazole biosynthetic gene cluster from Sorangium cellulosum. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: disorazole
PubChem ID: 44566233
SMILES string: Copy to clipboard
Molecular formula: C43H54N2O10
Average molecular mass: 758.909 Da

Class-specific details

Biosynthetic class(es):
NRP / Polyketide
Polyketide synthase subclass:
Trans-AT type I

Gene cluster description

disorazole (BGC0001093). Gene Cluster 1. Biosynthetic class = NRP/Polyketide. GenBank DQ013294. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

Literature references

1. Carvalho R et al. (2005) The biosynthetic genes for disorazoles, potent cytotoxic compounds that disrupt microtubule formation. Gene 359:91-8. doi: 10.1016/j.gene.2005.06.003.