BGC0001099: kalimantacin A biosynthetic gene cluster from Pseudomonas fluorescens
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Location: 1 - 77,317 nt. (total: 77,317 nt).
This entry is originally from NCBI GenBank GU479979.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
Polyketide
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001099
Short description kalimantacin A biosynthetic gene cluster from Pseudomonas fluorescens
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide (Other)
Loci NCBI GenBank: GU479979.1
Compounds
  • kalimantacin A
Species Pseudomonas fluorescens [taxonomy]
References
Chemical products information
kalimantacin A [synonyms: batumin, Kalimantacin]
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C30H48N2O7
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADD82939.1
  • bat1
 1 - 6720 (+) Bat1
  • Scaffold biosynthesis
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  • ADD82940.1
  • bat2
 6732 - 30773 (+) Bat2
  • Scaffold biosynthesis
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  • ADD82941.1
  • bat3
 30833 - 46282 (+) Bat3
  • Scaffold biosynthesis
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  • ADD82942.1
  • batA
 46406 - 46660 (+) BatA
  • Tailoring (Methylation)
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  • ADD82943.1
  • batB
 46650 - 47867 (+) BatB
  • Tailoring (Methylation)
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  • ADD82944.1
  • batC
 47898 - 49160 (+) BatC
  • Tailoring (Methylation)
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  • ADD82945.1
  • batD
 49148 - 49924 (+) BatD
  • Tailoring (Methylation)
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  • ADD82946.1
  • batE
 49921 - 50673 (+) BatE
  • Tailoring (Methylation)
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  • ADD82947.1
  • batF
 50799 - 52547 (+) BatF
  • Tailoring (Unknown)
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  • ADD82948.1
  • batG
 52666 - 53856 (+) BatG
  • Resistance/immunity
Heterologous expression
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  • ADD82949.1
  • batH
 53976 - 54941 (+) BatH
  • Scaffold biosynthesis
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  • ADD82950.1
  • batI
 54935 - 55732 (+) BatI
  • Unknown
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  • ADD82951.1
  • batJ
 55760 - 56626 (+) BatJ
  • Scaffold biosynthesis
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  • ADD82952.1
  • batK
 56666 - 58042 (+) BatK
  • Tailoring (Reduction)
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  • ADD82953.1
  • batL
 58092 - 60257 (+) BatL
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  • ADD82954.1
  • batM
 60289 - 61224 (+) BatM
  • Activation / processing
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  • ADD82955.1
  • batN
 62127 - 62894 (+) BatN
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  • ADD82956.1
  • batO
 62905 - 63216 (+) BatO
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  • ADD82957.1
  • batP
 63213 - 65792 (+) BatP
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  • ADD82958.1
  • batQ
 65850 - 67301 (+) BatQ
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  • ADD82959.1
  • batR
 67312 - 68625 (+) BatR
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  • ADD82960.1
  • batS
 68666 - 70339 (+) BatS
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  • ADD82961.1
  • batT
 70356 - 71141 (+) BatT
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  • ADD82962.1
  • batU
 71161 - 72189 (+) BatU
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  • ADD82963.1
  • batV
 72206 - 73342 (+) BatV
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  • ADD82964.1
  • batW
 73335 - 74156 (+) BatW
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  • ADD82965.1
  • batX
 74159 - 74416 (+) BatX
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  • ADD82966.1
  • batY
 74516 - 76252 (+) BatY
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  • ADD82967.1
  • batZ
 76274 - 77317 (+) BatZ
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Polyketide-specific information
Subclass Other
Starter unit Acetyl-CoA
Cyclic? no
Release type
  • Hydrolysis
Polyketide-synthases
Genes Properties Modules
batH
+
batJ
+
bat2
+
bat3
+
bat1 		Synthase subclass: Modular type I/Trans-AT type I
Trans-acyltansferases: batH, batJ
Module 0
Genes: bat1
Core domains: Thiolation (ACP/PCP)
Module 1
Genes: bat1
Core domains: Ketosynthase, Ketoreductase, Thiolation (ACP/PCP)
Scaffold-modifying domains: Methylation
KR-domain stereochemistry: L-OH
Module 3
Genes: bat2
Core domains: Ketosynthase, Ketoreductase, Thiolation (ACP/PCP)
KR-domain stereochemistry: L-OH
Module 4
Genes: bat2
Core domains: Ketosynthase, Ketoreductase, Thiolation (ACP/PCP)
KR-domain stereochemistry: L-OH
Module 5
Genes: bat2
Core domains: Ketosynthase, Thiolation (ACP/PCP)
Scaffold-modifying domains: Beta-branching
Module 6
Genes: bat2
Core domains: Ketosynthase, Ketoreductase, Dehydratase, Thiolation (ACP/PCP)
KR-domain stereochemistry: L-OH
Module 7
Genes: bat2
Core domains: Ketosynthase, Ketoreductase, Dehydratase, Thiolation (ACP/PCP)
KR-domain stereochemistry: D-OH
Module 8
Genes: bat3
Core domains: Ketosynthase, Ketoreductase, Dehydratase, Thiolation (ACP/PCP)
KR-domain stereochemistry: L-OH
Module 9
Genes: bat3
Core domains: Ketosynthase, Thiolation (ACP/PCP)
Scaffold-modifying domains: Beta-branching
Module 10
Genes: bat3
Core domains: Ketosynthase, Thiolation (ACP/PCP)
Scaffold-modifying domains: Beta-branching
Module 11
Genes: bat3
Core domains: Ketosynthase, Thiolation (ACP/PCP)
Scaffold-modifying domains: Beta-branching
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
bat2
Module 2
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Unknown
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: LBLIPTLAGFUPCXL63ODXWSCG, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Corrected polyketide synthase gene entries
  • Removed ketoreductase stereochemistry annotation from modules without ketoreductases
  • Fix trans AT gene IDs
  • Cleaned up synonym list
  • Changed amino acid substrates to lower case
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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