BGC0001106: oxazolomycin biosynthetic gene cluster from Streptomyces albus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 12,964 - 97,799 nt. (total: 84,836 nt).
This entry is originally from NCBI GenBank EF552687.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001106
Short description oxazolomycin biosynthetic gene cluster from Streptomyces albus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
EF552687.1
12964 - 97799
via Heterologous expression, Knock-out studies
Compounds
  • oxazolomycin
Species Streptomyces albus [taxonomy]
References
Chemical products information
oxazolomycin Evidence: NMR
Copy SMILES
C35H49N3O9
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABS90465.1
  • ozmA
 12964 - 14412 (+) transmembrane efflux protein
    copy AA seq
    copy Nt seq
    • ABA39082.2
    • ozmB
    		 14449 - 15549 (-) glyceroyl transferase/phosphatase
      copy AA seq
      copy Nt seq
      • ABS90466.1
      • ozmC
      		 15546 - 16523 (-) OzmC
        copy AA seq
        copy Nt seq
        • ABA39084.2
        • ozmD
        		 16520 - 17620 (-) acyl ACP dehydrogenase
          copy AA seq
          copy Nt seq
          • ABS90467.1
          • ozmE
          		 17613 - 17894 (-) acyl carrier protein
            copy AA seq
            copy Nt seq
            • ABS90468.1
            • ozmF
            		 17909 - 18574 (-) o-methyltransferase
              copy AA seq
              copy Nt seq
              • ABS90469.1
              • ozmG
              		 18574 - 19437 (-) glyceroyl ACP dehydrogenase
                copy AA seq
                copy Nt seq
                • ABS90470.1
                • ozmH
                		 20505 - 43718 (+) NRPS/PKS
                  copy AA seq
                  copy Nt seq
                  • ABS90471.1
                  • ozmJ
                  		 43715 - 52495 (+) PKS type I
                    copy AA seq
                    copy Nt seq
                    • ABS90472.1
                    • ozmK
                    		 52512 - 56120 (+) PKS
                      copy AA seq
                      copy Nt seq
                      • ABS90473.1
                      • ozmL
                      		 56198 - 62179 (+) NRPS
                        copy AA seq
                        copy Nt seq
                        • ABS90474.1
                        • ozmM
                        		 62230 - 65349 (+) malonyl CoA-ACP transferase
                          copy AA seq
                          copy Nt seq
                          • ABS90475.1
                          • ozmN
                          		 65423 - 80338 (+) PKS
                            copy AA seq
                            copy Nt seq
                            • ABS90476.1
                            • ozmO
                            		 80335 - 83925 (+) NRPS
                              copy AA seq
                              copy Nt seq
                              • ABS90477.1
                              • ozmP
                              		 83971 - 85119 (+) OzmP
                                copy AA seq
                                copy Nt seq
                                • ABS90478.1
                                • ozmQ
                                		 85129 - 87657 (+) PKS
                                  copy AA seq
                                  copy Nt seq
                                  • ABS90479.1
                                  • ozmR
                                  		 88376 - 89302 (-) transcriptional regulator
                                    copy AA seq
                                    copy Nt seq
                                    • ABS90480.1
                                    • ozmS
                                    		 89340 - 89984 (+) membrane protein
                                      copy AA seq
                                      copy Nt seq
                                      • ABS90481.1
                                      • ozmT
                                      		 90010 - 91329 (-) threonyl-tRNA synthetase
                                        copy AA seq
                                        copy Nt seq
                                        • ABS90482.1
                                        • ozmU
                                        		 92529 - 95318 (-) transcriptional activator
                                          copy AA seq
                                          copy Nt seq
                                          • ABS90483.1
                                          • ozmV
                                          		 95512 - 96849 (+) cytochrome P450
                                            copy AA seq
                                            copy Nt seq
                                            • ABS90484.1
                                            • ozmW
                                            		 97134 - 97799 (+) putative hydroxylase
                                              copy AA seq
                                              copy Nt seq
                                              Biosynthesis information
                                              Annotation changelog

                                              Entry version: next

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2023-11-02
                                              Corrected name of compound, added start:end coordinates, added BGC evidence.
                                              • (ID: ZF6B6VBOHAZ5KYONQR36C2NB)
                                              • (ID: C62OJVVH7XOTOTFZSJT727YU)

                                              Entry version: 4

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2022-10-07
                                              Update chemical activity to schema version 2.11
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 3

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2022-09-15
                                              Updated bioactivity data
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 2

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2019-10-16
                                              Migrated from v1.4
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              2019-10-16
                                              Updated compound(s) information (NPAtlas curation)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 1

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2015-06-12
                                              Submitted
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              Detailed domain annotation
                                              Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
                                              A domain glossary is available here, and an explanation of the visualisation is available here.
                                              Selected features only
                                              Show module domains
                                              Similar known gene clusters from MIBiG 4.0
                                              Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                              Click on reference genes to show details of similarities to genes within the current region.
                                              Click on an accession to open that entry in the MiBIG database.