BGC0001113: spliceostatin biosynthetic gene cluster from Burkholderia sp. FERM BP-3421
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Location: 1 - 93,443 nt. (total: 93,443 nt).
This entry is originally from NCBI GenBank KJ461964.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001113
Short description spliceostatin biosynthetic gene cluster from Burkholderia sp. FERM BP-3421
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • PKS (Unknown)
Loci
KJ461964.1
via
Compounds
  • spliceostatin
  • FR901464
Species Burkholderia sp. FERM BP-3421 [taxonomy]
References
Chemical products information
spliceostatin Evidence:
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C51H82N6O12S1
Chemical database entries
PubCHEM
FR901464 Evidence:
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C27H41N1O8
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AIC32690.1
  • fr9A
 3153 - 4037 (+) FR9A
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    • AIC32691.1
    • fr9B
    		 4352 - 5434 (+) FR9B
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      • AIC32692.1
      • fr9C
      		 5908 - 21093 (+) FR9C
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        • AIC32693.1
        • fr9DEF
        		 21115 - 44859 (+) FR9DEF
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          • AIC32694.1
          • fr9GH
          		 44915 - 59674 (+) FR9GH
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            • AIC32695.1
            • fr9I
            		 59676 - 68834 (+) FR9I
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              • AIC32696.1
              • fr9J
              		 68894 - 69784 (+) FR9J
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                • AIC32697.1
                • fr9K
                		 69795 - 71084 (+) FR9K
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                  • AIC32698.1
                  • fr9L
                  		 71102 - 71857 (+) FR9L
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                    • AIC32699.1
                    • fr9M
                    		 71933 - 72172 (+) FR9M
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                      • AIC32700.1
                      • fr9N
                      		 72165 - 73430 (+) FR9N
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                        • AIC32701.1
                        • fr9O
                        		 73442 - 74575 (+) FR9O
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                          • AIC32702.1
                          • fr9P
                          		 74909 - 75934 (+) FR9P
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                            • AIC32703.1
                            • fr9Q
                            		 76179 - 76616 (+) FR9Q
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                              • AIC32704.1
                              • fr9R
                              		 76711 - 78159 (+) FR9R
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                                Biosynthesis information

                                Biosynthetic modules

                                Name
                                Unk01
                                Type
                                nrps-type1
                                Genes
                                fr9DEF
                                Substrates
                                threonine (evidence: )
                                Integrated Monomers
                                Domains
                                adenylation
                                Annotation changelog

                                Entry version: 4

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2022-10-07
                                Update chemical activity to schema version 2.11
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 3

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2022-09-15
                                Updated bioactivity data
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                2022-09-15
                                Added NRP substrate specificities
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 2

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2019-10-16
                                Migrated from v1.4
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                Entry version: 1

                                Date
                                Changes
                                Submitters
                                Reviewers
                                2015-06-12
                                Submitted
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                Detailed domain annotation
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