BGC0001115: thiomarinol biosynthetic gene cluster from Pseudoalteromonas sp. SANK 73390
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Location: 10,748 - 97,600 nt. (total: 86,853 nt).
This entry is originally from NCBI GenBank FN689524.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
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NRP
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001115
Short description thiomarinol biosynthetic gene cluster from Pseudoalteromonas sp. SANK 73390
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: FN689524.1
Compounds
  • thiomarinol
Species Pseudoalteromonas sp. SANK 73390 [taxonomy]
References
Chemical products information
thiomarinol
Copy SMILES
C30H44N2O9S2
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CBK62717.1
  • tacpB
 10748 - 11083 (-)
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  • CBK62718.1
  • tmpF
 11086 - 13338 (-)
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  • CBK62719.1
  • tacpD
 13493 - 13828 (-)
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  • CBK62720.1
  • tmlS
 13822 - 14547 (-)
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  • CBK62721.1
  • tmlQ
 14561 - 15898 (-)
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  • CBK62722.1
  • tmlM
 16377 - 19523 (-)
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  • CBK62723.1
  • tmlA
 20098 - 21222 (+)
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  • CBK62724.1
  • tmpA
 21265 - 30297 (+)
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  • CBK62725.1
  • tacpC
 30294 - 30560 (+)
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  • CBK62726.1
  • tmlG
 30562 - 31779 (+)
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  • CBK62727.1
  • tmlH
 31803 - 33068 (+)
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  • CBK62728.1
  • tmlJ
 33091 - 33858 (+)
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  • CBK62729.1
  • tmpE
 33858 - 38192 (+)
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  • CBK62730.1
  • tmlL
 38189 - 39022 (+)
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  • CBK62731.1
  • tmpB
 39136 - 47388 (+)
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  • CBK62732.1
  • tmpC
 47452 - 50805 (+)
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  • CBK62733.1
  • tmpD
 50878 - 70959 (+)
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  • CBK62734.1
  • tmlB
 71058 - 71981 (+)
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  • CBK62735.1
  • tmlC
 72078 - 73217 (+)
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  • CBK62736.1
  • tmlF
 73267 - 74319 (+)
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  • CBK62737.1
  • tmlP
 74316 - 75236 (-)
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  • CBK62738.1
  • tmlO
 75246 - 76598 (-) cytochrome P450
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  • CBK62739.1
  • tmlU
 76680 - 78644 (-)
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  • CBK62740.1
  • tmlY
 78712 - 79242 (-)
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  • CBK62741.1
  • tmuA
 79587 - 80669 (-)
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  • CBK62742.1
  • tacpA
 81681 - 81962 (+)
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  • CBK62743.1
  • tmuB
 82295 - 83089 (+)
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  • CBK62744.1
  • tmlW
 83143 - 84546 (+)
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  • CBK62745.1
  • tmlZ
 84558 - 84941 (+)
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  • CBK62746.1
  • holA
 85410 - 88778 (+)
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  • CBK62747.1
  • holB
 88790 - 90415 (+)
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  • CBK62748.1
  • holC
 90412 - 91155 (+)
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  • CBK62749.1
  • holD
 91174 - 92310 (+)
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  • CBK62750.1
  • holE
 92330 - 93214 (+)
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  • CBK62751.1
  • holF
 93255 - 93719 (+)
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  • CBK62752.1
  • holG
 93773 - 94363 (+)
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  • CBK62753.1
  • holH
 94447 - 97557 (+)
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
holA
Module ?
Specificity: cysteine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
  • Knock-out studies
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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