BGC0001118 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001118 (Aspergillus fumigatus Af293)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	21,391	endocrocin	PKS:Iterative type I	100%

BGC0001118 - Region 1 - T1PKS

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Location: 1 - 21,391 nt. (total: 21,391 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 21,392
Label		BGC0001118

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001118	1.00	Polyketide	endocrocin	Aspergillus fumigatus Af293
BGC0001583	0.37	Polyketide	emodin	Escovopsis weberi
BGC0001284	0.36	Polyketide	alternariol	Parastagonospora nodorum SN15
BGC0000013	0.36	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0002154	0.35	Polyketide	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001906	0.35	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001258	0.35	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0002175	0.35	Polyketide	YWA1	Aspergillus oryzae RIB40
BGC0001257	0.35	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0000107	0.35	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001118	1.00	Polyketide	endocrocin	Aspergillus fumigatus Af293
BGC0001583	0.69	Polyketide	emodin	Escovopsis weberi
BGC0001284	0.69	Polyketide	alternariol	Parastagonospora nodorum SN15
BGC0000013	0.68	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0002154	0.68	Polyketide	1,3,5,8-tetrahydroxynapthalene, 1-(alpha-l-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8-trimethoxynaphthalene	Pyricularia oryzae 70-15
BGC0001906	0.68	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001258	0.68	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0002175	0.68	Polyketide	YWA1	Aspergillus oryzae RIB40
BGC0001257	0.68	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0000107	0.68	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 21391:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

AFUA_4G00210

PKS_AT (921..1220): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 95.0
inactive: 59.5
Methoxymalonyl-CoA: 38.5
Methylmalonyl-CoA: 36.6
Isobutyryl-CoA: 13.5
2-Methylbutyryl-CoA: 9.8
Benzoyl-CoA: 7.7
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0