BGC0001122: dihydroisoflavipucine biosynthetic gene cluster from Aspergillus terreus NIH2624
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Location: 901,119 - 944,781 nt. (total: 43,663 nt).
This entry is originally from NCBI GenBank CH476594.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Polyketide
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001122
Short description dihydroisoflavipucine biosynthetic gene cluster from Aspergillus terreus NIH2624
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide (Other)
Loci NCBI GenBank: CH476594.1
Compounds
  • dihydroisoflavipucine
  • isoflavipucine
Species Aspergillus terreus NIH2624 [taxonomy]
References
Chemical products information
dihydroisoflavipucine
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C12H17N1O4
Chemical database entries
NPAtlas
isoflavipucine
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C12H15N1O4
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATEG_00316
  • EAU38962.1
 901119 - 902332 (-) conserved hypothetical protein
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  • ATEG_00317
  • EAU38963.1
 902628 - 904618 (+) conserved hypothetical protein
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  • ATEG_00318
  • EAU38964.1
 905023 - 906498 (+) conserved hypothetical protein
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  • ATEG_00319
  • EAU38965.1
 907326 - 910637 (-) predicted protein
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  • ATEG_00320
  • EAU38966.1
 911158 - 913578 (-) heat shock protein 78, mitochondrial precursor
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  • ATEG_00321
  • EAU38967.1
 914036 - 915078 (+) elongation factor 1-beta
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  • ATEG_00322
  • EAU38968.1
 915466 - 916188 (+) conserved hypothetical protein
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  • ATEG_00323
  • EAU38969.1
 917231 - 917761 (+) predicted protein
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  • ATEG_00324
  • EAU38970.1
 918123 - 919320 (-) ubiquitin-conjugating enzyme E2S
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  • ATEG_00325
  • EAU38971.1
 919949 - 931962 (-) PKS-NRPS hybrid
  • Scaffold biosynthesis
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  • ATEG_00326
  • EAU38972.1
 933368 - 934642 (-) transcription factor
  • Regulation
Other in vivo study
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  • ATEG_00327
  • EAU38973.1
 936762 - 938081 (-) predicted protein
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  • ATEG_00328
  • EAU38974.1
 938542 - 939854 (-) predicted protein
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  • ATEG_00329
  • EAU38975.1
 940702 - 941242 (-) predicted protein
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  • ATEG_00330
  • EAU38976.1
 941766 - 942314 (-) predicted protein
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  • ATEG_00331
  • EAU38977.1
 942877 - 944781 (+) predicted protein
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Polyketide-specific information
Subclass Other
Starter unit Acetyl-CoA
Cyclic? no
Polyketide-synthases
Genes Properties Modules
ATEG_00325 Synthase subclass: Iterative type I
Iterative PKS type: Non-reducing, Unknown
Iteration counts: 2
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
ATEG_00325
Module 1
Specificity: leucine
Evidence for specificity:
Condensation domain type: Unknown
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: ZUAEFEJPIFGA5SNZGJWBG3IU, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Corrected gene identifiers
  • Changed amino acid substrates to lower case
Detailed domain annotation
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