BGC0001123 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001123 (Aspergillus oryzae RIB40)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	43,743	aspirochlorine	NRPS:Type I	100%

BGC0001123 - Region 1 - NRPS

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Location: 1 - 43,743 nt. (total: 43,743 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 43,744
Label		BGC0001123

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001123	0.76	NRP	aspirochlorine	Aspergillus oryzae RIB40
BGC0001989	0.31	Other	pulcherrimin	Kluyveromyces lactis
BGC0002321	0.31	Other	pulcherriminic acid, pulcherrimin, cyclodileucine, compound 3	Metschnikowia aff. pulcherrima
BGC0001547	0.27	Terpene	citreohybridonol	Aspergillus stellatus
BGC0000669	0.25	Terpene	marneral	Arabidopsis thaliana
BGC0002217	0.25	Terpene	HEx-tc3 terpene	Botrytis cinerea T4
BGC0000688	0.23	Terpene	copalyl diphosphate	Diaporthe amygdali
BGC0000685	0.23	Terpene	brassicicene C	Alternaria brassicicola ATCC 96836
BGC0002226	0.23	NRP	acu-dioxomorpholine B, acu-dioxomorpholine A	Aspergillus aculeatus ATCC 16872
BGC0002157	0.22	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001123	1.00	NRP	aspirochlorine	Aspergillus oryzae RIB40
BGC0002608	0.72	NRP, Polyketide	ochratoxin A	Aspergillus steynii
BGC0002670	0.69	Other	fosfonochlorin	Fusarium oxysporum f. sp. lycopersici 4287
BGC0001893	0.68	Other	abscisic acid	Botrytis cinerea B05.10
BGC0000677	0.66	Terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0002341	0.66	Other	3,5-dibromo-p-anisic acid	Planctomycetales bacterium 10988
BGC0001528	0.66	Terpene	betaestacin	Phoma betae
BGC0002721	0.65	Saccharide	α-hydroxynitrile glucoside, β-hydroxynitrile glucoside, γ-hydroxynitrile glucoside	Hordeum vulgare subsp. vulgare
BGC0001278	0.65	Terpene	nivalenol, deoxynivalenol, 3-acetyldeoxynivalenol, 15-acetyldeoxynivalenol, neosolaniol, calonectrin, apotrichodiol, isotrichotriol, 15-decalonectrin, T-2 toxin, 3-acetyl T-2 toxin, trichodiene	Fusarium sporotrichioides
BGC0002406	0.65	Other	hydroxycinnamoyltyramine	Oryza sativa Japonica Group

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 12890 - 43743:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Phe)

Direct lookup in NORINE database: strict or relaxed

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NRPS/PKS substrate predictions

AO090001000043

Search NORINE for peptide: strict or relaxed

AMP-binding (613..997): Phe

nrpys: Phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DGHIYVMCGK
Nearest Stachelhaus code(s):: Phe DGHIYVMCGK (91% 8Å match)
Stachelhaus code match:: 100% (strong)