BGC0001125: puwainaphycin A biosynthetic gene cluster from Cylindrospermum alatosporum CCALA 988
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Location: 1 - 56,729 nt. (total: 56,729 nt).
This entry is originally from NCBI GenBank KM078884.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001125
Short description puwainaphycin A biosynthetic gene cluster from Cylindrospermum alatosporum CCALA 988
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: KM078884.1
Compounds
  • puwainaphycin A
  • puwainaphycin B
  • puwainaphycin C
  • puwainaphycin D
Species Cylindrospermum alatosporum CCALA 988 [taxonomy]
References
Chemical products information
puwainaphycin A
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C58H98N12O17
Chemical database entries
PubCHEM
puwainaphycin B
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C59H100N12O16
Chemical database entries
PubCHEM
puwainaphycin C
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C56H95Cl1N12O16
Chemical database entries
NPAtlas
PubCHEM
puwainaphycin D
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C57H97Cl1N12O15
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AIW82276.1
  • orf1
 1 - 1980 (-) ORF1
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  • AIW82277.1
  • puwA
 2060 - 10672 (-) PuwA
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  • AIW82278.1
  • orf2
 10848 - 14198 (-) ORF2
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  • AIW82279.1
  • puwB
 16099 - 23703 (+) PuwB
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  • AIW82280.1
  • puwC
 23707 - 25500 (+) PuwC
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  • AIW82281.1
  • puwD
 25762 - 26067 (+) PuwD
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  • AIW82282.1
  • puwE
 26336 - 35569 (+) PuwE
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  • AIW82283.1
  • puwF
 35566 - 42678 (+) PuwF
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  • AIW82284.1
  • puwG
 42729 - 53207 (+) PuwG
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  • AIW82285.1
  • puwH
 53421 - 56729 (+) PuwH
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
puwA
Module ?
Specificity: asparagine
Evidence for specificity:
Module ?
Specificity: proline
Evidence for specificity:
puwE
Module ?
Specificity: valine
Evidence for specificity:
puwF
Module ?
Specificity: threonine
Evidence for specificity:
Module ?
Specificity: asparagine / glutamine
Evidence for specificity:
puwG
Module ?
Specificity: threonine
Evidence for specificity:
Module ?
Specificity: asparagine
Evidence for specificity:
Module ?
Specificity: alanine
Evidence for specificity:
puwH
Module ?
Specificity: threonine
Evidence for specificity:
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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