LOCUS       BGC0001125             56729 bp    DNA     linear   BCT 18-NOV-2014
DEFINITION  Cylindrospermum alatosporum CCALA 988 ORF1 (orf1) gene, complete
            cds; and puw gene cluster, complete sequence.
ACCESSION   BGC0001125
VERSION     BGC0001125
KEYWORDS    .
SOURCE      Cylindrospermum alatosporum CCALA 988
  ORGANISM  Cylindrospermum alatosporum CCALA 988
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae;
            Cylindrospermum.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:57:41
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 56729
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..1980)
                     /gene="orf1"
     CDS             complement(1..1980)
                     /codon_start=1
                     /gene="orf1"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 113.8; E-value:
                     1.7e-34)"
                     /gene_kind="transport"
                     /note="ABC transporter"
                     /product="ORF1"
                     /protein_id="AIW82276.1"
                     /transl_table=11
                     /translation="MNLPIAQKSNQNQVLTTDTSYRQFWKQFLAIAKPYWYPDPQDGRK
                     FLDVLFAWSQLGLILLLLLVINGINAYNSYVTRDLIDLLELKDTSAFFRLLFVYAKVLI
                     VLIPFIGLSQYLKRKIALDWYQFLNNYILDKYFQNRAYYKINFRSDIENPDQRIAQEIE
                     PIPRMATQIVFVFVEKTLDMITFLVVLWFIYKPVAIIVVIFGIVANLAAVLLSQRLIKI
                     NLAQVEGEADYSYSLTHVRDNAESVAFFRGEAQESNLVKRRFDKVIQALEQMTEWRRDQ
                     QIFNTSYQSFLSILPFIAIAPLYFFNQIDLGEVNQASTACNYFAAALALLVTEFGSSGR
                     LINLTQRLATFSEILESAKIQQESGRKIETVEGDRIAFEHITLQTPNYERVIIRDLSLS
                     VESGTGLLIVGPSGRGKSSLLRAVAGLWDAGIGRIVRPNLEEILFLPQRPYLVLGTLRD
                     QLLYPNRNHQITDQELELVLQQVNLPDLVSRVGGFDTEAYWENILSLGEQQRLAFARLL
                     VTCPRYVILDEATSALDLSNEENLYQKLQENGTTFISVGHRESLFNYHQWVLEFSGDSN
                     WRLVPTAEYSVSNEARTIEGLPETGSGIVPESMLESVPDYTSMKIEELRKLCQDKGIKW
                     RNARGAGKHLTKGEILAKLSEISP"
     source          1..56729
                     /collected_by="Alena Lukesova"
                     /country="Canada"
                     /culture_collection="CCALA:988"
                     /db_xref="taxon:1382618"
                     /isolate="Lukesova 1989/C24"
                     /isolation_source="soil, 3-4 years after wild fire, Riding
                     Mountain National Park"
                     /mol_type="genomic DNA"
                     /organism="Cylindrospermum alatosporum CCALA 988"
                     /strain="CCALA 988"
                     /type_material="reference strain of Cylindrospermum
                     alatosporum"
     protocluster    1..56729
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2059:56729]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2060..56729
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..56729
                     /SMILES="NC(C(O)C)C(=O)NC(C(O)C)C(=O)NC(CC(=O)N)C(=O)NC(C)C
                     (=O)NC(C(O)C)C(=O)NC([*])C(=O)CC(=O)NC(C(C)C)C(=O)C(C)CNC(C
                     C(=O)N(C))C(=O)N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..56729
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001125"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..56729
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..55569
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[16098:35569]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      16099..35569
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     gene            complement(2060..10672)
                     /gene="puwA"
     CDS             complement(2060..10672)
                     /NRPS_PKS="Domain: Condensation_LCL (47-348). E-value:
                     3.1e-123. Score: 402.4. Matches aSDomain:
                     nrpspksdomains_puwA_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (513-915). E-value:
                     1.1e-112. Score: 368.5. Matches aSDomain:
                     nrpspksdomains_puwA_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (1010-1231). E-value: 2.2e-117.
                     Score: 383.8. Matches aSDomain: nrpspksdomains_puwA_nMT.1"
                     /NRPS_PKS="Domain: PCP (1444-1512). E-value: 9.2e-26.
                     Score: 81.8. Matches aSDomain: nrpspksdomains_puwA_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1533-1834). E-value:
                     2.5e-123. Score: 402.7. Matches aSDomain:
                     nrpspksdomains_puwA_Condensation_LCL.2"
                     /NRPS_PKS="Domain: AMP-binding (1996-2401). E-value:
                     1.8e-111. Score: 364.4. Matches aSDomain:
                     nrpspksdomains_puwA_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2509-2578). E-value: 1.1e-27.
                     Score: 87.9. Matches aSDomain: nrpspksdomains_puwA_PCP.2"
                     /NRPS_PKS="Domain: Thioesterase (2597-2848). E-value:
                     1.5e-38. Score: 125.4. Matches aSDomain:
                     nrpspksdomains_puwA_Thioesterase.1"
                     /codon_start=1
                     /gene="puwA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     481.5; E-value: 4.8e-146)"
                     /gene_kind="biosynthetic"
                     /note="non-ribosomal peptide synthetase"
                     /product="PuwA"
                     /protein_id="AIW82277.1"
                     /sec_met_domain="Condensation (E-value: 5.1e-88, bitscore:
                     284.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 5.1e-122, bitscore:
                     396.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.1e-18, bitscore:
                     56.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLLKRLDHLSPEKRELVLKKLQMQKLSSATENKIQTLPIAPIP
                     RDQTIPLSFAQQRLWFLDQLVGPSATYNTPSALQMTGDLNVTALEQALAEIVHRHEALR
                     TSFQEINNTPVQVIAPRVTLALPVVDLQGLPNQEQSTEVKRLVMLEADKPFDLYQPPLL
                     RGTLLRLSENSHVLLLTVHHIVFDGWSMGVFIQELSVLYPAFAKGEPSPLPDLTVQYAD
                     FAVWQRQWLSGEVLETKLNYWRQKLAGAPPLLELPTDRPRPPVETFRGGLYPFQLNTHL
                     TQQLNSLSQKSGVTLFMTLQAAFVTLLHRYSGQDDILIGTPIANRNRQEIEPLIGFFVN
                     TLVLRTKLQGNPKFSDLLKQVQQVSLESYEYQDVPFEQVVEALQPERNLDHNPLFQVMF
                     VLQNAPTGTLKLLDLALTPLEMQTETAKRDLTLSLIENGEGLEGSWEYNRDLFDESTII
                     QMAGHFQTLLAEIVANPTQRIAHLPLLSESEQQRLLVEWNDTQADYPTHLCLHQWFEQQ
                     VQRTPEAVAVVWEDQRLTYSELNHRANQLANYLQTLGVAADVLVGICVERSLEMVVGLL
                     GILKAGGAYVPLDPAYPRDRLRYMLNDSQVPLLLTQSHLLDILPEEVNRILCLDSDWQA
                     IAHQSTDNVFSQVQPQNLAYIIYTSGSTGEPKGTMIRHQGVVNYLSWCTQAYAVADGCG
                     APVQSSFAFDATITSIFSPLMVGGQVVLLPEKQEIEALCDVLRSRRRFSLVKLTPAHLE
                     LLNQLLLPEELPESTQALVIGGEALLGKTLQFWQQYAPNIRLINEYGPTETVVGCCIYE
                     VTPETSLTEGILIGRPIANTQLYILDQFWQPVPIGVRGELYIGGAGVARGYLNRPELTA
                     ERFIRNPFSNDSEARLYKTGDLARYRLDGNIEYLGRMDNQVKLRGFRIELGEIEAAIAK
                     YPEVRETVVIIREDIPSDKRLVAYVVPNSQDGEDSEPAEDTEFQSEQLSQWQQVFNDSY
                     SQSVHDSDPTFNIIGWNDSRTGLLIPKTEMRQWVEATVERILYWQPHRVLEIGCGTGLL
                     LFRIAQQCQHYYGTDISHHALQYVEQQMSKLGGDWSQVQLAQGSADQFQEFETASFDAV
                     ILNSVVQYFPSIDYLIRVVATAVAANTPGGFIFIGDVRHLPLLEAFHTSVQFHQAPSSL
                     SAAELRQRVQRSLNQEPELVIDPAFFTALQHKFPQISHVQIQIKRGDYHNELTQFRYDV
                     TLHLGDKVTPLVVPQWLDWQQDDLTLTSLRELLTTTKPEILGIKQIPNARLQKEERLLD
                     LLFNTQESTTVGELNAVLPKVTPTTGVDPEALWAWEDELPYTVHINWSVTGNGDYDVVF
                     VRGASESASQSILPVFDQAKSVRPWSTYANNLLQGKLARKLIPQLRNFLKEKLPGYMIP
                     NAFMLLPVLPLTTNGKVDRVALPAPNLELSRTVSFVPPRTPAEEIIAEIIAEVLVLESV
                     GIYDNFFELGGHSLLATQVISRLQAAFQVELPLRCLFEAPTVTELDEFINNHRQTASGL
                     TTPAIAPTPRITPHLPMSWAQQRLWFLSQLEGASATYNMPNAVEITGDLQVDALKQALV
                     EIVRRHEILRTSFHLVEGSPVQVINPTATLTLPVVDLRKLPAEEHPLAVEQLSALEAQE
                     PFELEQAPLVRATLIQLGEKSHVLLFILHHIVCDGWSMGILIQELSVLYPAFAANKPSP
                     LPELPIQYADFAVWQRQWLSGDVLDTKLNYWKQQLADASPVLELPTDKPRPAVQTFRGD
                     RCNFAIKQDLSQQINRLSQQTGTTLFMTLQAAFVTLLHRYSGQDDILIGTPIANRNRQE
                     IEPLIGFFVNTLVLRTKVDNNPKFSEVLTQVRQVALDAYSHQDVPFEQVVEALQPDRKL
                     SHSPLFQVMFAMQNAPMGNLELPGLNFTPLEIENVTAKFDLTLAIWETKEGLTGWWEYN
                     SDLFEAETICRMIGHFETLLTAIATNPDQRLSQLPMLTEQEQQLFGEWNSTQTEYTAES
                     IPQLFTAQVQRTPDAVAVLFGQDQLTYRELDARANQLAHHLQTLGVGPEVVVGICLERS
                     LDLVIGLLGIIKAGGAYLPLDPAYPRDRLGYMLKDSQAAVLLTQSHLIDILPEHESRLV
                     CLDTEWQSSLTQIQPEPANSRLQPDNLAYVIYTSGSTGTPKGVAMTQGALTNLLLWQIR
                     QTHIAASAKTLQFAPVSFDVSFQEMFTTWCAGGTLVLVPDALRRDATALLGLLSEQSVE
                     RVFLPFVALQQLAEAAAGVESLPPLREIMTAGEQLQITPALKNFLRRLPGCSLHNQYGP
                     SETHVVTAFSLEDGLEELPALPPIGRPIDNTQIYILDRQMQQVPIGVRGELYIGGVGVA
                     RGYLNRPDLTEERFIPDFFTNSKVNRLYKTGDGARYLPDGNIEYLGRMDDQVKVRGFRI
                     ELGEIEAVLGLHPQVQQAIAIAYGETAAEKRLVVYVVLSPEQPATPEQLRKFLQQRLPE
                     YMIPSVFIPLETVPLTPSGKVDRRSLPAPFNINQPPTAIAPRDPLELQLAQIWSEVLAV
                     DWVGIRDNFFEIGGHSLLAIRLMAQIQQQFGKQLPLATLFQSPTIEELANLLRQSTDTT
                     IWSSLVPIQPVGTNTPFFCVPGAGGNVIYFYELARCLGANQPFYSLQPQGLDGESAPMT
                     QIEDIAAHYITAIQTVQPQGPYLLGGHSFGGLVAFEMAQQLQQQGHEIALLAILDTTAP
                     IPPDQSVEVELDDTTWLVQIGTAIERLFGKSLNISPEILQPLTAEAQLDYLLEQLKITN
                     ILPADAGKAQFRGFIQVYKTHTQAFSNYFPQSVHKSPITLLRASEMSDEEAAIEGYIER
                     LQEPTLGWSKFSTEPVEIHIVPGTHLTMMVKPNVQVLAEKLGTSIRHATSDR"
     misc_feature    2060..56729
                     /note="puw gene cluster"
     aSDomain        complement(2129..2881)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_Thioesterase.1"
                     /evalue="1.50E-38"
                     /label="puwA_Thioesterase.1"
                     /locus_tag="puwA"
                     /protein_end="2848"
                     /protein_start="2597"
                     /score="125.4"
                     /tool="antismash"
                     /translation="PFFCVPGAGGNVIYFYELARCLGANQPFYSLQPQGLDGESAPMTQ
                     IEDIAAHYITAIQTVQPQGPYLLGGHSFGGLVAFEMAQQLQQQGHEIALLAILDTTAPI
                     PPDQSVEVELDDTTWLVQIGTAIERLFGKSLNISPEILQPLTAEAQLDYLLEQLKITNI
                     LPADAGKAQFRGFIQVYKTHTQAFSNYFPQSVHKSPITLLRASEMSDEEAAIEGYIERL
                     QEPTLGWSKFSTEPVEIHIVPGTHLTMMV"
     aSModule        complement(2129..6073)
                     /complete
                     /domains="nrpspksdomains_puwA_Condensation_LCL.2"
                     /domains="nrpspksdomains_puwA_AMP-binding.2"
                     /domains="nrpspksdomains_puwA_PCP.2"
                     /domains="nrpspksdomains_puwA_Thioesterase.1"
                     /final_module
                     /locus_tags="puwA"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2627..2701)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0023"
                     /evalue="6.10E-15"
                     /label="NRPS-te1"
                     /locus_tag="puwA"
                     /protein_end="2682"
                     /protein_start="2657"
                     /score="47.4"
                     /tool="antismash"
                     /translation="QPQGPYLLGGHSFGGLVAFEMAQQL"
     aSDomain        complement(2939..3145)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_PCP.2"
                     /evalue="1.10E-27"
                     /label="puwA_PCP.2"
                     /locus_tag="puwA"
                     /protein_end="2578"
                     /protein_start="2509"
                     /score="87.9"
                     /tool="antismash"
                     /translation="ELQLAQIWSEVLAVDWVGIRDNFFEIGGHSLLAIRLMAQIQQQFG
                     KQLPLATLFQSPTIEELANLLRQS"
     CDS_motif       complement(3440..3505)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0022"
                     /evalue="1.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwA"
                     /protein_end="2411"
                     /protein_start="2389"
                     /score="39.9"
                     /tool="antismash"
                     /translation="YLGRMDDQVKVRGFRIELGEIE"
     aSDomain        complement(3470..4684)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_AMP-binding.2"
                     /evalue="1.80E-111"
                     /label="puwA_AMP-binding.2"
                     /locus_tag="puwA"
                     /protein_end="2401"
                     /protein_start="1996"
                     /score="364.4"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="FTAQVQRTPDAVAVLFGQDQLTYRELDARANQLAHHLQTLGVGPE
                     VVVGICLERSLDLVIGLLGIIKAGGAYLPLDPAYPRDRLGYMLKDSQAAVLLTQSHLID
                     ILPEHESRLVCLDTEWQSSLTQIQPEPANSRLQPDNLAYVIYTSGSTGTPKGVAMTQGA
                     LTNLLLWQIRQTHIAASAKTLQFAPVSFDVSFQEMFTTWCAGGTLVLVPDALRRDATAL
                     LGLLSEQSVERVFLPFVALQQLAEAAAGVESLPPLREIMTAGEQLQITPALKNFLRRLP
                     GCSLHNQYGPSETHVVTAFSLEDGLEELPALPPIGRPIDNTQIYILDRQMQQVPIGVRG
                     ELYIGGVGVARGYLNRPDLTEERFIPDFFTNSKVNRLYKTGDGARYLPDGNIEYLGRMD
                     DQVKVR"
     CDS_motif       complement(3593..3682)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0021"
                     /evalue="5.60E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="puwA"
                     /protein_end="2360"
                     /protein_start="2330"
                     /score="57.0"
                     /tool="antismash"
                     /translation="PIGVRGELYIGGVGVARGYLNRPDLTEERF"
     CDS_motif       complement(3791..3823)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0020"
                     /evalue="2.70E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="puwA"
                     /protein_end="2294"
                     /protein_start="2283"
                     /score="4.7"
                     /tool="antismash"
                     /translation="QYGPSETHVVT"
     CDS_motif       complement(4205..4261)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0019"
                     /evalue="2.60E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="puwA"
                     /protein_end="2156"
                     /protein_start="2137"
                     /score="29.1"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVAMT"
     CDS_motif       complement(4457..4498)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0018"
                     /evalue="1.30E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="puwA"
                     /protein_end="2072"
                     /protein_start="2058"
                     /score="15.3"
                     /tool="antismash"
                     /translation="LGIIKAGGAYLPLD"
     CDS_motif       complement(5015..5134)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0017"
                     /evalue="3.40E-25"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="puwA"
                     /protein_end="1886"
                     /protein_start="1846"
                     /score="80.5"
                     /tool="antismash"
                     /translation="RQVALDAYSHQDVPFEQVVEALQPDRKLSHSPLFQVMFAM"
     aSDomain        complement(5171..6073)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_Condensation_LCL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.50E-123"
                     /label="puwA_Condensation_LCL.2"
                     /locus_tag="puwA"
                     /protein_end="1834"
                     /protein_start="1533"
                     /score="402.7"
                     /tool="antismash"
                     /translation="HLPMSWAQQRLWFLSQLEGASATYNMPNAVEITGDLQVDALKQAL
                     VEIVRRHEILRTSFHLVEGSPVQVINPTATLTLPVVDLRKLPAEEHPLAVEQLSALEAQ
                     EPFELEQAPLVRATLIQLGEKSHVLLFILHHIVCDGWSMGILIQELSVLYPAFAANKPS
                     PLPELPIQYADFAVWQRQWLSGDVLDTKLNYWKQQLADASPVLELPTDKPRPAVQTFRG
                     DRCNFAIKQDLSQQINRLSQQTGTTLFMTLQAAFVTLLHRYSGQDDILIGTPIANRNRQ
                     EIEPLIGFFVNTLVLRTKVD"
     CDS_motif       complement(5183..5272)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0016"
                     /evalue="6.00E-18"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwA"
                     /protein_end="1830"
                     /protein_start="1800"
                     /score="57.1"
                     /tool="antismash"
                     /translation="DILIGTPIANRNRQEIEPLIGFFVNTLVLR"
     CDS_motif       complement(5525..5563)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0015"
                     /evalue="3.50E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="puwA"
                     /protein_end="1716"
                     /protein_start="1703"
                     /score="19.4"
                     /tool="antismash"
                     /translation="QYADFAVWQRQWL"
     CDS_motif       complement(5612..5677)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0014"
                     /evalue="2.70E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="puwA"
                     /protein_end="1687"
                     /protein_start="1665"
                     /score="39.0"
                     /tool="antismash"
                     /translation="LHHIVCDGWSMGILIQELSVLY"
     CDS_motif       complement(5894..6010)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0013"
                     /evalue="1.10E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwA"
                     /protein_end="1593"
                     /protein_start="1554"
                     /score="56.4"
                     /tool="antismash"
                     /translation="ATYNMPNAVEITGDLQVDALKQALVEIVRRHEILRTSFH"
     CDS_motif       complement(6032..6061)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0012"
                     /evalue="7.40E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="puwA"
                     /protein_end="1547"
                     /protein_start="1537"
                     /score="6.3"
                     /tool="antismash"
                     /translation="SWAQQRLWFL"
     aSDomain        complement(6137..6340)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_PCP.1"
                     /evalue="9.20E-26"
                     /label="puwA_PCP.1"
                     /locus_tag="puwA"
                     /protein_end="1512"
                     /protein_start="1444"
                     /score="81.8"
                     /tool="antismash"
                     /translation="EEIIAEIIAEVLVLESVGIYDNFFELGGHSLLATQVISRLQAAFQ
                     VELPLRCLFEAPTVTELDEFINN"
     aSModule        complement(6137..10531)
                     /complete
                     /domains="nrpspksdomains_puwA_Condensation_LCL.1"
                     /domains="nrpspksdomains_puwA_AMP-binding.1"
                     /domains="nrpspksdomains_puwA_nMT.1"
                     /domains="nrpspksdomains_puwA_PCP.1"
                     /locus_tags="puwA"
                     /monomer_pairings="Asn -> NMe-Asn"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(6980..7642)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_nMT.1"
                     /domain_subtypes="nMT"
                     /evalue="2.20E-117"
                     /label="puwA_nMT.1"
                     /locus_tag="puwA"
                     /protein_end="1231"
                     /protein_start="1010"
                     /score="383.8"
                     /tool="antismash"
                     /translation="GLLIPKTEMRQWVEATVERILYWQPHRVLEIGCGTGLLLFRIAQQ
                     CQHYYGTDISHHALQYVEQQMSKLGGDWSQVQLAQGSADQFQEFETASFDAVILNSVVQ
                     YFPSIDYLIRVVATAVAANTPGGFIFIGDVRHLPLLEAFHTSVQFHQAPSSLSAAELRQ
                     RVQRSLNQEPELVIDPAFFTALQHKFPQISHVQIQIKRGDYHNELTQFRYDVTLHLGD"
     CDS_motif       complement(7898..7963)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0011"
                     /evalue="4.80E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwA"
                     /protein_end="925"
                     /protein_start="903"
                     /score="37.8"
                     /tool="antismash"
                     /translation="YLGRMDNQVKLRGFRIELGEIE"
     aSDomain        complement(7928..9133)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_AMP-binding.1"
                     /evalue="1.10E-112"
                     /label="puwA_AMP-binding.1"
                     /locus_tag="puwA"
                     /protein_end="915"
                     /protein_start="513"
                     /score="368.5"
                     /specificity="substrate consensus: Asn"
                     /tool="antismash"
                     /translation="FEQQVQRTPEAVAVVWEDQRLTYSELNHRANQLANYLQTLGVAAD
                     VLVGICVERSLEMVVGLLGILKAGGAYVPLDPAYPRDRLRYMLNDSQVPLLLTQSHLLD
                     ILPEEVNRILCLDSDWQAIAHQSTDNVFSQVQPQNLAYIIYTSGSTGEPKGTMIRHQGV
                     VNYLSWCTQAYAVADGCGAPVQSSFAFDATITSIFSPLMVGGQVVLLPEKQEIEALCDV
                     LRSRRRFSLVKLTPAHLELLNQLLLPEELPESTQALVIGGEALLGKTLQFWQQYAPNIR
                     LINEYGPTETVVGCCIYEVTPETSLTEGILIGRPIANTQLYILDQFWQPVPIGVRGELY
                     IGGAGVARGYLNRPELTAERFIRNPFSNDSEARLYKTGDLARYRLDGNIEYLGRMDNQV
                     KLR"
     CDS_motif       complement(8051..8140)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0010"
                     /evalue="4.90E-19"
                     /label="NRPS-A_a6"
                     /locus_tag="puwA"
                     /protein_end="874"
                     /protein_start="844"
                     /score="60.3"
                     /tool="antismash"
                     /translation="PIGVRGELYIGGAGVARGYLNRPELTAERF"
     CDS_motif       complement(8255..8281)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0009"
                     /evalue="5.40E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="puwA"
                     /protein_end="806"
                     /protein_start="797"
                     /score="3.9"
                     /tool="antismash"
                     /translation="EYGPTETVV"
     CDS_motif       complement(8654..8713)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0008"
                     /evalue="9.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="puwA"
                     /protein_end="673"
                     /protein_start="653"
                     /score="30.5"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGEPKGTMIRH"
     CDS_motif       complement(8906..8947)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0007"
                     /evalue="9.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="puwA"
                     /protein_end="589"
                     /protein_start="575"
                     /score="18.7"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       complement(9470..9589)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0006"
                     /evalue="5.50E-23"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="puwA"
                     /protein_end="401"
                     /protein_start="361"
                     /score="73.4"
                     /tool="antismash"
                     /translation="QQVSLESYEYQDVPFEQVVEALQPERNLDHNPLFQVMFVL"
     aSDomain        complement(9629..10531)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwA_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.10E-123"
                     /label="puwA_Condensation_LCL.1"
                     /locus_tag="puwA"
                     /protein_end="348"
                     /protein_start="47"
                     /score="402.4"
                     /tool="antismash"
                     /translation="QTIPLSFAQQRLWFLDQLVGPSATYNTPSALQMTGDLNVTALEQA
                     LAEIVHRHEALRTSFQEINNTPVQVIAPRVTLALPVVDLQGLPNQEQSTEVKRLVMLEA
                     DKPFDLYQPPLLRGTLLRLSENSHVLLLTVHHIVFDGWSMGVFIQELSVLYPAFAKGEP
                     SPLPDLTVQYADFAVWQRQWLSGEVLETKLNYWRQKLAGAPPLLELPTDRPRPPVETFR
                     GGLYPFQLNTHLTQQLNSLSQKSGVTLFMTLQAAFVTLLHRYSGQDDILIGTPIANRNR
                     QEIEPLIGFFVNTLVLRTKL"
     CDS_motif       complement(9638..9727)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0005"
                     /evalue="6.00E-18"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwA"
                     /protein_end="345"
                     /protein_start="315"
                     /score="57.1"
                     /tool="antismash"
                     /translation="DILIGTPIANRNRQEIEPLIGFFVNTLVLR"
     CDS_motif       complement(9980..10018)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0004"
                     /evalue="3.50E-06"
                     /label="C4_LCL_164-176"
                     /locus_tag="puwA"
                     /protein_end="231"
                     /protein_start="218"
                     /score="19.4"
                     /tool="antismash"
                     /translation="QYADFAVWQRQWL"
     CDS_motif       complement(10067..10132)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0003"
                     /evalue="4.30E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="puwA"
                     /protein_end="202"
                     /protein_start="180"
                     /score="38.4"
                     /tool="antismash"
                     /translation="VHHIVFDGWSMGVFIQELSVLY"
     CDS_motif       complement(10352..10465)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0002"
                     /evalue="5.50E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwA"
                     /protein_end="107"
                     /protein_start="69"
                     /score="54.1"
                     /tool="antismash"
                     /translation="ATYNTPSALQMTGDLNVTALEQALAEIVHRHEALRTSF"
     CDS_motif       complement(10484..10516)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwA_0001"
                     /evalue="5.80E-03"
                     /label="C1_LCL_004-017"
                     /locus_tag="puwA"
                     /protein_end="63"
                     /protein_start="52"
                     /score="9.4"
                     /tool="antismash"
                     /translation="SFAQQRLWFLD"
     gene            complement(10848..14198)
                     /gene="orf2"
     CDS             complement(10848..14198)
                     /codon_start=1
                     /gene="orf2"
                     /note="patatin-like phospholipase"
                     /product="ORF2"
                     /protein_id="AIW82278.1"
                     /transl_table=11
                     /translation="MAQATQSVLEFDGQNDFVELPGKSIPSGSEITVSFWSYGGSLSPK
                     HSSIIGAQGPNNERILNIHLPWGESKIYFDSGNQASGFDRIEKLAQASEYKQKWSHWAF
                     TKNVTTGEMKIYLNGELWHSGTGKTMPLIPATRVTLGCFSNSQLYHHGMISELQIWNKA
                     RSQDEIKADMARRLVGNEPGLVGYWPLNEGAGTTVKDKTNNANHGTISGNAAWVQAELP
                     IEVKQQPAPPKLQPVLSFDGQNDYINCPEGIVTNSYTKEAWVKLAEPLSQHNNILSGRN
                     HALFMPNGLLGSGHNGQWWFVKDSSTSPANTWFHVAVTYDSQTKVMCLYRDGRLVSQAS
                     DVQPFDPSDRTLQIGSHNSSFLFKGQIAEARVWNKVLSQTEIQSNLSHRLVGNEPGLVX
                     YWPLNEGTGTTVQDKTNNANHGNISGNAAWVQAEIPIEVKQPPTPSKLQPVLSLDGQDD
                     YVELPGKSIPSGSEITVSFWSNAGTLQPKYSSIIEARSDNNTRLFNIHLPWQNSIIYFD
                     CGDLTGYDRITKTMPVSDYRNKWLHWAFTKNATTGEMKIYVNGELWHSESNKTKPISPA
                     AKVCLGCYTDLQNYHHGMISELQIWNKARSQDEIKADMAYRLVGNEPGLVGYWPLNEGT
                     GTTVQDKTKNANHGTISGNAAWLQAEIPIEVKQPQPPTAPQEQPQPDPQPETPVVTQEQ
                     SQPDPQPETPVVTQEQSQPDPQPETPVVTQEQPQPNPQPDIQGQPLVIIQEHSESAIVK
                     QPQTQQKKRTYPYRILSIDGGGIRGIIPAMILAEIERRTEKPISSMFDLFAGTSTGGIL
                     ALGLTKPKPNPNAPAYSEGVPEPAYSAQALVSMFAKYGSEIFYEPIIEELLGNLDDIIK
                     PKYTSEGREDVLKRFFDFTPLQETLKEVFITSYDIELRTPVFFTSNPKKQNTQSHSYRR
                     ICRGFTMKQAAMATSAAPTYFSPYRIQTSQSPSSFYNLVDGGVFANNPTSLALMEALNN
                     AKAAAKRGEETWTIDDILVVSLGTGSLTKVYPYNEARNWGLIGWVRPLINIILDATSQS
                     VSCELEQLLRAPDNSQKQYYRFQAYLDERLEPMDNAKAENIRMLTRVAKQIIDEREEDI
                     DELCNELMR"
     gene            16099..23703
                     /gene="puwB"
     CDS             16099..23703
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (5-429). E-value:
                     1.2e-187. Score: 615.9. Matches aSDomain:
                     nrpspksdomains_puwB_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (540-838). E-value: 2.1e-110.
                     Score: 360.6. Matches aSDomain:
                     nrpspksdomains_puwB_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH2 (933-1144). E-value: 3.8e-37.
                     Score: 119.7. Matches aSDomain:
                     nrpspksdomains_puwB_PKS_DH2.1"
                     /NRPS_PKS="Domain: cMT (1382-1583). E-value: 4.3e-105.
                     Score: 343.4. Matches aSDomain: nrpspksdomains_puwB_cMT.1"
                     /NRPS_PKS="Domain: PKS_ER (1818-2125). E-value: 1.8e-123.
                     Score: 403.5. Matches aSDomain:
                     nrpspksdomains_puwB_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (2137-2314). E-value: 2.9e-70.
                     Score: 227.8. Matches aSDomain:
                     nrpspksdomains_puwB_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2403-2483). E-value: 7.2e-27.
                     Score: 85.5. Matches aSDomain:
                     nrpspksdomains_puwB_PKS_PP.1"
                     /codon_start=1
                     /gene="puwB"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 116.7; E-value:
                     1.8e-35)"
                     /gene_kind="biosynthetic"
                     /note="polyketide synthetase"
                     /product="PuwB"
                     /protein_id="AIW82279.1"
                     /sec_met_domain="hyb_KS (E-value: 1.1e-195, bitscore:
                     639.9, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 3.7e-111, bitscore:
                     360.6, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 1.7e-08, bitscore: 23.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.8e-20, bitscore:
                     60.9, seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 8.4e-66, bitscore:
                     210.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-16, bitscore:
                     50.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNEPIAIIGIGCRFPGIKTPEGFWHLLRDGVDAISEVPKTRWDI
                     ESFYDPDPAIPGKMSTKWGGFLEQVEQFDPQFFGISPREAAGIDPQQRLLLEVAWEALE
                     DAGQKPEQLVGKPVGVFTGISTFDYYWHWMRNPSQTDAYFATGTANCMAANRISYTFNF
                     TGPSLAIDTACSSSLVAVHLACQSLGNGESTLALAGGVNVMTSPWLFVGFSKSGFMAPD
                     GRCKTFDSRANGYVRSEGGGFVVLKLLSQALADGDRIYAVIRGSAINQDGRSNGLTAPN
                     SLAQEAVLRDAYRQAGVSPGRVQYIEAHGTGTKLGDPIEMKALGKVLSEDRPPGEICSV
                     GAVKTNIGHTEAAAGIAGLIKVALSLKNQQIPPSLHFLEANPYIPFDKLPLRVQQTLEP
                     WPTGVGNALAGVSSFGFGGTNAHVVLEAAPQEIQNSKFKIQKDDQSNRSVHLLTLSAKN
                     ETALQALAESYQEYLRSHPDESLANICFTSNIGRSHFEYRLAIATASTQELSQQLEAFT
                     TGSETRGLVQGKITSRKGSKIAFLFTGQGSQYIGMGRQLYETQPSFRSTINHCEERLSP
                     YLEKPLLEILYPQEESGVNTQHFLDETAYTQPALFILEYAIAKLWQSWGIEPAVVLGHS
                     VGEYVAACIAGVFSLEDGLKLIAARGRLMQTLPPDGAMVAVLADEKTVIAAIQPYNEQL
                     SIAAINGVESLVISGQWQAIESVCLALNNQGVKTKPLQVSHAFHSPLMKPILGAFEEVA
                     KTITYSSPKIPLISNVTGQPATTDIATPEYWCHHISQPVKFAASMATLQQQGYEVFVEI
                     GPKPTLLGMGRQCLPEAKGLWLPSLHPRQTDWQQILESLAALYVRGIPVDWVKFNSDYE
                     YSRVSLPTYPFQRQRYWLDTAELPTHQPQLSHQNLHPLLGQRLQLAGLKEIRFESHISQ
                     DQPAYLKDHRVFGEVIFPAAAYLEMVLAAGAKLFKSDSLVLEDVSILQALILSEEIRKL
                     QLSLTPQGNAAYSFQIFSCSATEEEPSWMLHVSGKLLRGENPSTPAQTDLEKQCQQDID
                     TITYYQQCSDRGIDYGFSFQAIEKLWQSEELTTGKVQLPLALVAEAGDYTIHPVLLDAC
                     FQLLGTALPNQNQPDTYLPIGIELLQIDRRPGNHVWSQVQINPPQDANQQILSGDLSLY
                     TPEGQRIAQIKGFQLQRANHGDVLNETPENWQNWLYQVEWRQQVRFISQNLPPNYLPSP
                     QEMSLKLSPDLAELVKRFNLEGSGDVFSHLEKLSLTYIIRAFADMKWKFQLGQRFSTAD
                     ISTQLGVINQHQRLLGRLLEILAEGGYLRQINSQWEVIKVPQESNPEAQLKILFQQYPT
                     AAAELTLLGRCGCKLADVLRGNSDPLQLLFPEGDLTTATQVYQDSPGAKLLNTQVQQAI
                     SSAVARLPKDRGVRVLEIGAGTGGTTTYILPVLPAQQTEYVFTDLSPRFTTQAEEKFRE
                     YPFVKYQVLDIEQDLKSQGFEFHQYDLIVAANVLHATQDLRQTLQNIRQLLAPNGLLVL
                     LEGTARQRWLDLTFGLTEGWWWFTDTDLRPNYPLLTNNQWQNLLLQVGYQAAVTLPLVQ
                     ESQSVIVAQAGSSQLTVAAAQPKHWLLLCDNHGLGEQLAAQLRQKGEICTLVFPGELAE
                     KLDEQTFAINPQQPEDFQQLLRDISHQPAIHGVVHCWSLDTVGADVLKSSDLQGASQQS
                     CGSTLHLVQGLVKASLSPRLWLVTRGAQSVGDAVSGVAQSAIWGLGKVIALEHPELKCV
                     RVDLDPDVLGDAAPALFAEVWADDAEDQVAFRNGLRYVARLIRSAQSEIPLNQPFTLTI
                     SQRGTLENLTFQPAVRRLPDAGEVEIRVRATGLNFRDLLNALDLYPGDPGPLGGECAGE
                     IVAIGAGVEGFAVGDAVIAIAPATFSQYATVNAALVAPKPANLSFEEATTIPITFLTAY
                     YALHHLAKIAPGERVLIHAAAGGVGQAAIQLAQQVGAEVFATASPGKWEFLKSLGVQHI
                     MNSRTVEFAEQIGEITGGEGVNIVLNSLTSDEFIAKSLSVLSSQGRFVEIAKRGVLDTE
                     EMLAVRSDIAYFLVDLVLVCQQQPALIQSMLRHLMPQFAAGKLQPLPQTVFPIQNVVDA
                     FRYMQQAKHIGKIVVTQPAELTLRGDRTYLITGGMGGLGLLIARWMVENGAKHLVLLGR
                     SIPSKSAIETLEVLQNKGAEVMVVQADVTDVAQMTQVIAEIERSHFPLSGVIHAVGVLD
                     DGVLQQQTWERFARVMAPKVEGAWHLHQLTQNLPLDFFVLFSSVASLFGSPGQANHAAA
                     NGFLDALAAYRQQQGLPGLSINWGVVADIGAAAKRQADGWVKTKGMGTISPPQVLEILA
                     QQLQTPAAAQVGVVPVDWSKFIAQSTPWSFFSDFQQTDDSQEQPSQNSELRQQLEVIPK
                     NEQRAYLTNYLCTQVAKVLGLNSSTSIDIQQGFFDLGMDSLTSVELRNRLQTSLGCSLP
                     STLTFKYPTVAALVDYLAVEVLALATTVEITPQETKVNQELEAVKQLSKDELEDSIAQE
                     IAELEALLRGN"
     aSDomain        16114..17385
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="1.20E-187"
                     /label="puwB_PKS_KS.1"
                     /locus_tag="puwB"
                     /protein_end="429"
                     /protein_start="5"
                     /score="615.9"
                     /tool="antismash"
                     /translation="IAIIGIGCRFPGIKTPEGFWHLLRDGVDAISEVPKTRWDIESFYD
                     PDPAIPGKMSTKWGGFLEQVEQFDPQFFGISPREAAGIDPQQRLLLEVAWEALEDAGQK
                     PEQLVGKPVGVFTGISTFDYYWHWMRNPSQTDAYFATGTANCMAANRISYTFNFTGPSL
                     AIDTACSSSLVAVHLACQSLGNGESTLALAGGVNVMTSPWLFVGFSKSGFMAPDGRCKT
                     FDSRANGYVRSEGGGFVVLKLLSQALADGDRIYAVIRGSAINQDGRSNGLTAPNSLAQE
                     AVLRDAYRQAGVSPGRVQYIEAHGTGTKLGDPIEMKALGKVLSEDRPPGEICSVGAVKT
                     NIGHTEAAAGIAGLIKVALSLKNQQIPPSLHFLEANPYIPFDKLPLRVQQTLEPWPTGV
                     GNALAGVSSFGFGGTNAHVVLEAAP"
     aSModule        16114..23547
                     /complete
                     /domains="nrpspksdomains_puwB_PKS_KS.1"
                     /domains="nrpspksdomains_puwB_PKS_AT.1"
                     /domains="nrpspksdomains_puwB_PKS_DH2.1"
                     /domains="nrpspksdomains_puwB_cMT.1"
                     /domains="nrpspksdomains_puwB_PKS_ER.1"
                     /domains="nrpspksdomains_puwB_PKS_KR.1"
                     /domains="nrpspksdomains_puwB_PKS_PP.1"
                     /locus_tags="puwB"
                     /monomer_pairings="mal -> Me-redmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       16591..16638
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0001"
                     /evalue="1.70E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="puwB"
                     /protein_end="180"
                     /protein_start="164"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GPSLAIDTACSSSLVA"
     CDS_motif       16780..16818
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0002"
                     /evalue="5.20E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="puwB"
                     /protein_end="240"
                     /protein_start="227"
                     /score="13.1"
                     /tool="antismash"
                     /translation="FDSRANGYVRSEG"
     CDS_motif       17011..17058
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0003"
                     /evalue="1.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="puwB"
                     /protein_end="320"
                     /protein_start="304"
                     /score="13.7"
                     /tool="antismash"
                     /translation="YIEAHGTGTKLGDPIE"
     CDS_motif       17119..17163
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0004"
                     /evalue="1.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="puwB"
                     /protein_end="355"
                     /protein_start="340"
                     /score="11.1"
                     /tool="antismash"
                     /translation="GAVKTNIGHTEAAAG"
     aSDomain        17719..18612
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_PKS_AT.1"
                     /evalue="2.10E-110"
                     /label="puwB_PKS_AT.1"
                     /locus_tag="puwB"
                     /protein_end="838"
                     /protein_start="540"
                     /score="360.6"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYIGMGRQLYETQPSFRSTINHCEERLSPYLEKPLLEI
                     LYPQEESGVNTQHFLDETAYTQPALFILEYAIAKLWQSWGIEPAVVLGHSVGEYVAACI
                     AGVFSLEDGLKLIAARGRLMQTLPPDGAMVAVLADEKTVIAAIQPYNEQLSIAAINGVE
                     SLVISGQWQAIESVCLALNNQGVKTKPLQVSHAFHSPLMKPILGAFEEVAKTITYSSPK
                     IPLISNVTGQPATTDIATPEYWCHHISQPVKFAASMATLQQQGYEVFVEIGPKPTLLGM
                     GRQCLPEAKGLWLPSLH"
     CDS_motif       17722..17769
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0005"
                     /evalue="2.30E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="puwB"
                     /protein_end="557"
                     /protein_start="541"
                     /score="19.9"
                     /tool="antismash"
                     /translation="FTGQGSQYIGMGRQLY"
     CDS_motif       17899..17967
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0006"
                     /evalue="6.10E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="puwB"
                     /protein_end="623"
                     /protein_start="600"
                     /score="13.1"
                     /tool="antismash"
                     /translation="DETAYTQPALFILEYAIAKLWQS"
     CDS_motif       17971..18093
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0007"
                     /evalue="5.00E-29"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="puwB"
                     /protein_end="665"
                     /protein_start="624"
                     /score="92.8"
                     /tool="antismash"
                     /translation="GIEPAVVLGHSVGEYVAACIAGVFSLEDGLKLIAARGRLMQ"
     CDS_motif       18379..18411
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0008"
                     /evalue="2.70E-03"
                     /label="PKSI-AT-M_m7"
                     /locus_tag="puwB"
                     /protein_end="771"
                     /protein_start="760"
                     /score="10.5"
                     /tool="antismash"
                     /translation="PKIPLISNVTG"
     CDS_motif       18445..18480
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0009"
                     /evalue="3.90E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="puwB"
                     /protein_end="794"
                     /protein_start="782"
                     /score="10.8"
                     /tool="antismash"
                     /translation="YWCHHISQPVKF"
     aSDomain        18898..19530
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_PKS_DH2.1"
                     /evalue="3.80E-37"
                     /label="puwB_PKS_DH2.1"
                     /locus_tag="puwB"
                     /protein_end="1144"
                     /protein_start="933"
                     /score="119.7"
                     /tool="antismash"
                     /translation="AYLKDHRVFGEVIFPAAAYLEMVLAAGAKLFKSDSLVLEDVSILQ
                     ALILSEEIRKLQLSLTPQGNAAYSFQIFSCSATEEEPSWMLHVSGKLLRGENPSTPAQT
                     DLEKQCQQDIDTITYYQQCSDRGIDYGFSFQAIEKLWQSEELTTGKVQLPLALVAEAGD
                     YTIHPVLLDACFQLLGTALPNQNQPDTYLPIGIELLQIDRRPGNHVWS"
     CDS_motif       18901..18978
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0010"
                     /evalue="2.40E-13"
                     /label="PKSI-DH_m2"
                     /locus_tag="puwB"
                     /protein_end="960"
                     /protein_start="934"
                     /score="42.4"
                     /tool="antismash"
                     /translation="YLKDHRVFGEVIFPAAAYLEMVLAAG"
     aSDomain        20245..20847
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="4.30E-105"
                     /label="puwB_cMT.1"
                     /locus_tag="puwB"
                     /protein_end="1583"
                     /protein_start="1382"
                     /score="343.4"
                     /tool="antismash"
                     /translation="QVYQDSPGAKLLNTQVQQAISSAVARLPKDRGVRVLEIGAGTGGT
                     TTYILPVLPAQQTEYVFTDLSPRFTTQAEEKFREYPFVKYQVLDIEQDLKSQGFEFHQY
                     DLIVAANVLHATQDLRQTLQNIRQLLAPNGLLVLLEGTARQRWLDLTFGLTEGWWWFTD
                     TDLRPNYPLLTNNQWQNLLLQVGYQAAVTLPLVQESQS"
     aSDomain        21553..22473
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_PKS_ER.1"
                     /evalue="1.80E-123"
                     /label="puwB_PKS_ER.1"
                     /locus_tag="puwB"
                     /protein_end="2125"
                     /protein_start="1818"
                     /score="403.5"
                     /tool="antismash"
                     /translation="GTLENLTFQPAVRRLPDAGEVEIRVRATGLNFRDLLNALDLYPGD
                     PGPLGGECAGEIVAIGAGVEGFAVGDAVIAIAPATFSQYATVNAALVAPKPANLSFEEA
                     TTIPITFLTAYYALHHLAKIAPGERVLIHAAAGGVGQAAIQLAQQVGAEVFATASPGKW
                     EFLKSLGVQHIMNSRTVEFAEQIGEITGGEGVNIVLNSLTSDEFIAKSLSVLSSQGRFV
                     EIAKRGVLDTEEMLAVRSDIAYFLVDLVLVCQQQPALIQSMLRHLMPQFAAGKLQPLPQ
                     TVFPIQNVVDAFRYMQQAKHIGKIVV"
     CDS_motif       21862..21906
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0011"
                     /evalue="6.80E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="puwB"
                     /protein_end="1936"
                     /protein_start="1921"
                     /score="13.1"
                     /tool="antismash"
                     /translation="ATTIPITFLTAYYAL"
     CDS_motif       21931..21993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0012"
                     /evalue="4.20E-11"
                     /label="PKSI-ER_m5"
                     /locus_tag="puwB"
                     /protein_end="1965"
                     /protein_start="1944"
                     /score="34.9"
                     /tool="antismash"
                     /translation="GERVLIHAAAGGVGQAAIQLA"
     CDS_motif       22003..22050
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0013"
                     /evalue="1.70E-04"
                     /label="PKSI-ER_m6"
                     /locus_tag="puwB"
                     /protein_end="1984"
                     /protein_start="1968"
                     /score="14.4"
                     /tool="antismash"
                     /translation="GAEVFATASPGKWEFL"
     CDS_motif       22120..22158
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0014"
                     /evalue="8.60E-04"
                     /label="PKSI-ER_m7"
                     /locus_tag="puwB"
                     /protein_end="2020"
                     /protein_start="2007"
                     /score="12.0"
                     /tool="antismash"
                     /translation="TGGEGVNIVLNSL"
     CDS_motif       22426..22473
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0015"
                     /evalue="5.20E-08"
                     /label="PKSI-ER_m9"
                     /locus_tag="puwB"
                     /protein_end="2125"
                     /protein_start="2109"
                     /score="25.4"
                     /tool="antismash"
                     /translation="AFRYMQQAKHIGKIVV"
     CDS_motif       22510..22608
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0016"
                     /evalue="4.80E-19"
                     /label="PKSI-KR_m1"
                     /locus_tag="puwB"
                     /protein_end="2170"
                     /protein_start="2137"
                     /score="60.9"
                     /tool="antismash"
                     /translation="TYLITGGMGGLGLLIARWMVENGAKHLVLLGRS"
     aSDomain        22510..23040
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_PKS_KR.1"
                     /evalue="2.90E-70"
                     /label="puwB_PKS_KR.1"
                     /locus_tag="puwB"
                     /protein_end="2314"
                     /protein_start="2137"
                     /score="227.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TYLITGGMGGLGLLIARWMVENGAKHLVLLGRSIPSKSAIETLEV
                     LQNKGAEVMVVQADVTDVAQMTQVIAEIERSHFPLSGVIHAVGVLDDGVLQQQTWERFA
                     RVMAPKVEGAWHLHQLTQNLPLDFFVLFSSVASLFGSPGQANHAAANGFLDALAAYRQQ
                     QGLPGLSINWGVVA"
     CDS_motif       22834..22863
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0017"
                     /evalue="4.60E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="puwB"
                     /protein_end="2255"
                     /protein_start="2245"
                     /score="10.5"
                     /tool="antismash"
                     /translation="PKVEGAWHLH"
     CDS_motif       22885..22995
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwB_0018"
                     /evalue="5.40E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="puwB"
                     /protein_end="2299"
                     /protein_start="2262"
                     /score="67.2"
                     /tool="antismash"
                     /translation="LDFFVLFSSVASLFGSPGQANHAAANGFLDALAAYRQ"
     aSDomain        23308..23547
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwB_PKS_PP.1"
                     /evalue="7.20E-27"
                     /label="puwB_PKS_PP.1"
                     /locus_tag="puwB"
                     /protein_end="2483"
                     /protein_start="2403"
                     /score="85.5"
                     /tool="antismash"
                     /translation="PKNEQRAYLTNYLCTQVAKVLGLNSSTSIDIQQGFFDLGMDSLTS
                     VELRNRLQTSLGCSLPSTLTFKYPTVAALVDYLAV"
     gene            23707..25500
                     /gene="puwC"
     CDS             23707..25500
                     /NRPS_PKS="Domain: CAL_domain (62-506). E-value: 1.2e-134.
                     Score: 441.4. Matches aSDomain:
                     nrpspksdomains_puwC_CAL_domain.1"
                     /codon_start=1
                     /gene="puwC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     398.1; E-value: 7.6e-121)"
                     /gene_kind="biosynthetic-additional"
                     /note="fatty acyl-AMP ligase (FAAL)"
                     /product="PuwC"
                     /protein_id="AIW82280.1"
                     /sec_met_domain="AMP-binding (E-value: 2.9e-95, bitscore:
                     308.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNSTFNIQHSTFNIVRLSAHDEVQNPHFSTFVELLRYRAISQPD
                     KIAFTFLQDGETETGSLTYQALDQQAKAIAVQLESVAAKGDRAIMLYPSGLEFITAFFG
                     CLYAGVVAIPAYPPRRNQNLFRLQSIVTDAQATVALTTTALSSDLKQWFNQNSELATVK
                     WLVTDEIDSNLASVWQQPELNSNTLAFLQYTSGSTGTPKGVMVSHSNLLYNEEMIKLGF
                     QNTEQSIIAGWLPFFHDMGLMANLLQAVYLGVPCFFMPPVAFLQRPYRWLQVISRYKAT
                     SSGAPNFAYDLCVNKITPEQISSLDLSSWDLAFNGAEPVNAATLERFTAKFAAYGFRRE
                     AFYPGYGMAEATLLISGGLRKAAPVVLSVAGSNLEQNRVLVTTDEQEGSKKIVGCGQTW
                     LDQKIAIADPDTLTHCSAEQVGEIWVSGANVAGGYWNRPEETEQTFHSYFADTGEGPFL
                     RTGDLGFLRDGELFITGRIKDVIIIRGRNNYPQDIEVTVEQSHPALRPSNGAAFTVTVN
                     EQEKLIVVQEVERTWLRKLDGETVVKTIRQAVAQQHELQVYAVVLIKTGSIPKTSSGKI
                     QRRACRAKFLAGTLEGLTSDK"
     aSDomain        23893..25224
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwC_CAL_domain.1"
                     /evalue="1.20E-134"
                     /label="puwC_CAL_domain.1"
                     /locus_tag="puwC"
                     /protein_end="506"
                     /protein_start="62"
                     /score="441.4"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TYQALDQQAKAIAVQLESVAAKGDRAIMLYPSGLEFITAFFGCLY
                     AGVVAIPAYPPRRNQNLFRLQSIVTDAQATVALTTTALSSDLKQWFNQNSELATVKWLV
                     TDEIDSNLASVWQQPELNSNTLAFLQYTSGSTGTPKGVMVSHSNLLYNEEMIKLGFQNT
                     EQSIIAGWLPFFHDMGLMANLLQAVYLGVPCFFMPPVAFLQRPYRWLQVISRYKATSSG
                     APNFAYDLCVNKITPEQISSLDLSSWDLAFNGAEPVNAATLERFTAKFAAYGFRREAFY
                     PGYGMAEATLLISGGLRKAAPVVLSVAGSNLEQNRVLVTTDEQEGSKKIVGCGQTWLDQ
                     KIAIADPDTLTHCSAEQVGEIWVSGANVAGGYWNRPEETEQTFHSYFADTGEGPFLRTG
                     DLGFLRDGELFITGRIKDVIIIRGRNNYPQDIEVTVEQSHPALRP"
     CDS_motif       24271..24330
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwC_0001"
                     /evalue="6.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="puwC"
                     /protein_end="208"
                     /protein_start="188"
                     /score="31.0"
                     /tool="antismash"
                     /translation="AFLQYTSGSTGTPKGVMVSH"
     CDS_motif       24964..25041
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwC_0002"
                     /evalue="3.90E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="puwC"
                     /protein_end="445"
                     /protein_start="419"
                     /score="38.4"
                     /tool="antismash"
                     /translation="VGEIWVSGANVAGGYWNRPEETEQTF"
     CDS_motif       25126..25188
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwC_0003"
                     /evalue="1.70E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="puwC"
                     /protein_end="494"
                     /protein_start="473"
                     /score="17.5"
                     /tool="antismash"
                     /translation="TGRIKDVIIIRGRNNYPQDIE"
     gene            25762..26067
                     /gene="puwD"
     CDS             25762..26067
                     /NRPS_PKS="Domain: ACP (32-94). E-value: 4.7e-16. Score:
                     50.8. Matches aSDomain: nrpspksdomains_puwD_ACP.1"
                     /codon_start=1
                     /gene="puwD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047:phosphopantetheine-binding domain-containing
                     protein (Score: 80.4; E-value: 1.5e-24)"
                     /gene_kind="biosynthetic-additional"
                     /note="acyl carrier protein"
                     /product="PuwD"
                     /protein_id="AIW82281.1"
                     /sec_met_domain="PP-binding (E-value: 2.8e-14, bitscore:
                     42.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSEQITQELIELRGKKQIPSLTEIQDWLIVYTAEMLESSPDEID
                     VTMLFDQYGLDSSMTVGMIGDLEVWLGCELDPTLIYDYSTIELLSQHLGSILATKN"
     aSDomain        25858..26043
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwD_ACP.1"
                     /evalue="4.70E-16"
                     /label="puwD_ACP.1"
                     /locus_tag="puwD"
                     /protein_end="94"
                     /protein_start="32"
                     /score="50.8"
                     /tool="antismash"
                     /translation="TAEMLESSPDEIDVTMLFDQYGLDSSMTVGMIGDLEVWLGCELDP
                     TLIYDYSTIELLSQHLG"
     gene            26336..35569
                     /gene="puwE"
     CDS             26336..35569
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (38-465). E-value:
                     4e-186. Score: 610.8. Matches aSDomain:
                     nrpspksdomains_puwE_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (570-866). E-value: 1.5e-113.
                     Score: 371.0. Matches aSDomain:
                     nrpspksdomains_puwE_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (949-1017). E-value: 3.4e-15.
                     Score: 48.3. Matches aSDomain:
                     nrpspksdomains_puwE_PP-binding.1"
                     /NRPS_PKS="Domain: Aminotran_3 (1197-1524). E-value: 2e-50.
                     Score: 163.5. Matches aSDomain:
                     nrpspksdomains_puwE_Aminotran_3.1"
                     /NRPS_PKS="Domain: Condensation_LCL (2010-2316). E-value:
                     8e-87. Score: 282.8. Matches aSDomain:
                     nrpspksdomains_puwE_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (2480-2877). E-value:
                     9.3e-117. Score: 381.9. Matches aSDomain:
                     nrpspksdomains_puwE_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (2985-3053). E-value: 4.4e-25.
                     Score: 79.6. Matches aSDomain: nrpspksdomains_puwE_PCP.1"
                     /codon_start=1
                     /gene="puwE"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 103.3; E-value:
                     2e-31)"
                     /gene_kind="biosynthetic"
                     /note="hybrid polyketide synthetase/non-ribosomal peptide
                     synthetase; aminotransferase; monooxygenase"
                     /product="PuwE"
                     /protein_id="AIW82282.1"
                     /sec_met_domain="hyb_KS (E-value: 9.9e-212, bitscore:
                     692.7, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.6e-114, bitscore:
                     371.0, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_3 (E-value: 6.7e-56, bitscore:
                     179.0, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 6.7e-76, bitscore:
                     244.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-127, bitscore:
                     414.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3e-18, bitscore:
                     55.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNISEAVEQLSSSQRMLLALKEARAKLEAFDRAKTEPIAIIGMG
                     CRFPGNANNPEAFWQLLRDGVDAITEVPKSRWDIDEFYDPDPHQPGKIYTRYGGFLSDV
                     DQFDPQFFGIAPREAVSMAPQQRLLLEVGWEALENAGINPKKLVGSPTGVFLGVGPNDY
                     AKLRMNASEPAGITAHDGTGNGLCFASGRLSYVLGLQGPNLATDTSCSSSLVAVHLACQ
                     SLRAGESNLALAGGVNLNLFPETTLFLSRTHALAPDGRCKTFDAAADGFSRSEGCGVIV
                     LKRLSDALADGDRIWAMIRGSAINHDGPSSGLTVPNQLAQEQLIRQALQNAKVTPEQVS
                     YIEAHGTGTSLGDPIEVGALAAIFCQNRSLEEPLMIGSVKTNLGHLEAAAGIVGLMKAA
                     LALHHGEIPPHLHFQQPNPHITWDNLPVVVPTTRTPWNRGDKPLIAGVSSFGMSGTNAH
                     IVLEAAPQEIKNSKLKVKKDVNLLTLSAKNQSALAELAQSYQEYLQAHPEISLADICFT
                     ANTGRSHFDHRLAVVAASPVELQEHLQNFAAGKEAFGLLHNQVTQRQQPKIAFLFTGQG
                     SQYLDMGRQLYDTQPIFRQTLDRCDEILRPYLEKPLLEVLYPQSPLNSQSLDETAYTQP
                     ALFALEYALYELWRSWGIKPNAVVGHSLGEYVAACVAGVFSLEDGLKLIAQRAQLMQSL
                     KAKGSMVAVFAPESKVLSAIQPYIKEVAIAAINGTENIVISGQQQAVEAVVAVLEAENI
                     KTRSLTVSHAFHSPLVEPMLAEFAVILQQISFQPPQIPVISNLTGKVLAAGEIPDANYW
                     KRHTREPVRFMDGVNALFELGCGIFLELGPKPILTNLGKQCQPENNAVWLSCLAAGRDD
                     WHLLLNTLSALYVQGVAINWLGFEQDYPHSLVSLPTYPFQRQSYWIENNNAPINSQSSQ
                     TSQPLISMPIQTQRRAEIQEKLRSLIAQVLQVPLNGVDVHTSFLEMGADSIFLMEGVRT
                     IENTFGIKIAMRQFFEELSTLEALATYIDLQLPPAVAEVNPLPSEPSQPATPIQPTTNV
                     VVTSPVNSISNGAVSVAGGAMERLMAQQLQVMSEQLAVLRGTPLSVQPISPSSNGNGTN
                     GHGTNGHGANSNFKNVPKPSSNPLAPQPISSAGGLTPQQQRHLEALINRYTQRTQKSKQ
                     RAQASRPHLADNRAVAGFRMGIKEMLYPIVGTRYQGANFWDLDGNEYVDLAMGFGTHLF
                     GHGATFLNQAIHEQIKQGIAVGPQPALALEVCELLCELTGSERATFCQSGSEAVMVALR
                     LARTATKRDRIALFTGSYHGHFDGVLAQAQEMSAQPLAPGIAPNTVKDVLVLDYGDPRA
                     LEILKAEMHTLAAVLVEPVQSRRPDLQPREFLHELRQITQAGGTALIFDEIMTGFRIHQ
                     GGAQAHFGVQADLATYSKIFGGGLPLAAIAGNAKFMNGIDGGFWNYSDQSYPQADRTFF
                     AGTFNKHPLSLSTCRAALRHLKEQGTQLQTELNQRTEYLVEQLNQFFTEQEVELRVVNF
                     GSLFRFVFKSNLDVFFYHLLEKGVYIWEGRTCFLSTAHTEADINWIIRAVKESIQEMRV
                     GGFFPELAQNGRVQEKTPVSQNGFWERRSHKYAAVSSKPTALRAKTSVDPNKTVQFSLY
                     YFGNYESEFSHDKYNLLFAGAKYADQHGFTAVWIPERHFHAFGGFSPNPSVIAAAIARE
                     TKQIQIRSGSVVLPLHHPIRVVEEWSVVDNLSQGRVGISFASGWNPNDFALAPQSFGNH
                     RELMFQGIETVRKLWRGEFIQVQNGVGKSISVQAFPRPMQAELPDWITVVNNPETYIKA
                     GEMGSGVLTNLMGQSIEDLAENIALYRESLEKHGYNPASGKVTVLLHTFVGQDLEQTRE
                     IARQPLCDYLKSSVALFQNLVKSQGLQVDFDQMTADDQDYILSAAYNRYVQSSALIGTP
                     ASCAEVIAKLQAIGVDEVACLIDFGVNTPAVVESLPDLNALRELCQPKTGEQEKEPSPL
                     PIASLPLASLPIASLPLSPIPLTEAQKQLWVLAQMGDDGSIAYNESVSQQLRGSLNLVA
                     MNQAIQQLVERHEALRTTISPQGDVQKILPELKLDLAVIDFSELTNSDGLRPAGSDRTS
                     QVTAWLTQESQSPFDLSSGPLFRVHLLKLEAKLHLLVLSAHHIIVDGWSLGVILQELSA
                     LYSAACQGVDCQLKPPMQFRQYIEWQTQQSQTAEMAEHEAYWLQQFANSIPVLDLPCDR
                     TRSPIKTYQGSKQSIILDASLSRAIKRVSTEQGATLFMTLLSVYTALLHRLTGQDEIVV
                     GIPTSGRSLEGSEGLVGYCAHVLPIRSSVIGSSSFSEYLLAIRDVLLDAYKHQDYPFAK
                     LIQALNLTRDASRSPLVATTFNLDRAAAVPKLFELETSWFAQPISFTDYDIHWNITQIN
                     DELVVDCNYNTDLFEAETIQRWLGHFQTLLLAVVANPTQSMGQLPLLTETERQQLLVTW
                     NATQTDYPADKCIHQQFEVQVQKTPDAVALLWEDQQLTYAQLNVRANQLAHYLRKQGVG
                     PDVPVGICMERSIDLVVGLLGILKAGGAYVPLDPDYPQERLSWILEDVKPLVLLTQSRL
                     VNQLPRTKIVCLDAETATIAQESTENLVPEVKADHLAYIMYTSGSTGKPKGVSIIHRGV
                     VRLVQATNYVALTAAEVFLQLAPISFDASTFEIWGSLLNGAKLVIMPIPKGTLEELGQV
                     IRENQVTTIWLTASLFHLMVDERLDDLKSVRQLLAGGDVLSVTHVQKVFQHLPHCRLIN
                     GYGPTENTTFTCCFPMTAETQIGASVPIGRPIANTLVYILDANLQPVPIGVWGELYIGG
                     AGLAQGYFNRPDLTQEKFIANPFEDSKFNRLYKTGDLARYLPDGNIEFLGRIDQQVKIR
                     GFRIELGEIAAILANHPQVKQAVAIAHTDTSGNKRLVAYFVPDGEKPSSSELRNWLKKK
                     IPDYMLPEVFVCLESLPLNSNGKVDRFALPLPDLELYRSVKFVAPRTATEQAIANIVAE
                     VLNIEQVGIDDNFFELGGNSLNANQVISRLRQTFRVELPLRNLLEEPTVVELATSMDQI
                     RATVQKLQSSPSDLLEDREEIEV"
     aSDomain        26450..27730
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="4.00E-186"
                     /label="puwE_PKS_KS.1"
                     /locus_tag="puwE"
                     /protein_end="465"
                     /protein_start="38"
                     /score="610.8"
                     /tool="antismash"
                     /translation="IAIIGMGCRFPGNANNPEAFWQLLRDGVDAITEVPKSRWDIDEFY
                     DPDPHQPGKIYTRYGGFLSDVDQFDPQFFGIAPREAVSMAPQQRLLLEVGWEALENAGI
                     NPKKLVGSPTGVFLGVGPNDYAKLRMNASEPAGITAHDGTGNGLCFASGRLSYVLGLQG
                     PNLATDTSCSSSLVAVHLACQSLRAGESNLALAGGVNLNLFPETTLFLSRTHALAPDGR
                     CKTFDAAADGFSRSEGCGVIVLKRLSDALADGDRIWAMIRGSAINHDGPSSGLTVPNQL
                     AQEQLIRQALQNAKVTPEQVSYIEAHGTGTSLGDPIEVGALAAIFCQNRSLEEPLMIGS
                     VKTNLGHLEAAAGIVGLMKAALALHHGEIPPHLHFQQPNPHITWDNLPVVVPTTRTPWN
                     RGDKPLIAGVSSFGMSGTNAHIVLEAAP"
     aSModule        26450..30907
                     /complete
                     /domains="nrpspksdomains_puwE_PKS_KS.1"
                     /domains="nrpspksdomains_puwE_PKS_AT.1"
                     /domains="nrpspksdomains_puwE_PP-binding.1"
                     /domains="nrpspksdomains_puwE_Aminotran_3.1"
                     /locus_tags="puwE"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       26936..26983
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0001"
                     /evalue="2.30E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="puwE"
                     /protein_end="216"
                     /protein_start="200"
                     /score="13.6"
                     /tool="antismash"
                     /translation="GPNLATDTSCSSSLVA"
     CDS_motif       27356..27403
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0002"
                     /evalue="2.90E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="puwE"
                     /protein_end="356"
                     /protein_start="340"
                     /score="13.0"
                     /tool="antismash"
                     /translation="YIEAHGTGTSLGDPIE"
     CDS_motif       27464..27508
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0003"
                     /evalue="1.40E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="puwE"
                     /protein_end="391"
                     /protein_start="376"
                     /score="11.2"
                     /tool="antismash"
                     /translation="GSVKTNLGHLEAAAG"
     aSDomain        28046..28933
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_PKS_AT.1"
                     /evalue="1.50E-113"
                     /label="puwE_PKS_AT.1"
                     /locus_tag="puwE"
                     /protein_end="866"
                     /protein_start="570"
                     /score="371.0"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYLDMGRQLYDTQPIFRQTLDRCDEILRPYLEKPLLEV
                     LYPQSPLNSQSLDETAYTQPALFALEYALYELWRSWGIKPNAVVGHSLGEYVAACVAGV
                     FSLEDGLKLIAQRAQLMQSLKAKGSMVAVFAPESKVLSAIQPYIKEVAIAAINGTENIV
                     ISGQQQAVEAVVAVLEAENIKTRSLTVSHAFHSPLVEPMLAEFAVILQQISFQPPQIPV
                     ISNLTGKVLAAGEIPDANYWKRHTREPVRFMDGVNALFELGCGIFLELGPKPILTNLGK
                     QCQPENNAVWLSCLA"
     CDS_motif       28049..28096
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0004"
                     /evalue="6.50E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="puwE"
                     /protein_end="587"
                     /protein_start="571"
                     /score="18.6"
                     /tool="antismash"
                     /translation="FTGQGSQYLDMGRQLY"
     CDS_motif       28217..28285
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0005"
                     /evalue="6.50E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="puwE"
                     /protein_end="650"
                     /protein_start="627"
                     /score="13.0"
                     /tool="antismash"
                     /translation="DETAYTQPALFALEYALYELWRS"
     CDS_motif       28289..28411
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0006"
                     /evalue="3.10E-28"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="puwE"
                     /protein_end="692"
                     /protein_start="651"
                     /score="90.2"
                     /tool="antismash"
                     /translation="GIKPNAVVGHSLGEYVAACVAGVFSLEDGLKLIAQRAQLMQ"
     CDS_motif       28505..28543
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0007"
                     /evalue="3.40E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="puwE"
                     /protein_end="736"
                     /protein_start="723"
                     /score="10.8"
                     /tool="antismash"
                     /translation="AAINGTENIVISG"
     CDS_motif       28766..28801
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0008"
                     /evalue="4.90E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="puwE"
                     /protein_end="822"
                     /protein_start="810"
                     /score="16.6"
                     /tool="antismash"
                     /translation="YWKRHTREPVRF"
     aSDomain        29183..29386
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_PP-binding.1"
                     /evalue="3.40E-15"
                     /label="puwE_PP-binding.1"
                     /locus_tag="puwE"
                     /protein_end="1017"
                     /protein_start="949"
                     /score="48.3"
                     /tool="antismash"
                     /translation="EKLRSLIAQVLQVPLNGVDVHTSFLEMGADSIFLMEGVRTIENTF
                     GIKIAMRQFFEELSTLEALATYI"
     aSDomain        29927..30907
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_Aminotran_3.1"
                     /evalue="2.00E-50"
                     /label="puwE_Aminotran_3.1"
                     /locus_tag="puwE"
                     /protein_end="1524"
                     /protein_start="1197"
                     /score="163.5"
                     /tool="antismash"
                     /translation="TRYQGANFWDLDGNEYVDLAMGFGTHLFGHGATFLNQAIHEQIKQ
                     GIAVGPQPALALEVCELLCELTGSERATFCQSGSEAVMVALRLARTATKRDRIALFTGS
                     YHGHFDGVLAQAQEMSAQPLAPGIAPNTVKDVLVLDYGDPRALEILKAEMHTLAAVLVE
                     PVQSRRPDLQPREFLHELRQITQAGGTALIFDEIMTGFRIHQGGAQAHFGVQADLATYS
                     KIFGGGLPLAAIAGNAKFMNGIDGGFWNYSDQSYPQADRTFFAGTFNKHPLSLSTCRAA
                     LRHLKEQGTQLQTELNQRTEYLVEQLNQFFTEQEVELRVVNFGSLF"
     CDS_motif       30362..30397
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0009"
                     /evalue="1.60E+01"
                     /label="C3_dual_135-156"
                     /locus_tag="puwE"
                     /protein_end="1354"
                     /protein_start="1342"
                     /score="-1.0"
                     /tool="antismash"
                     /translation="ALEILKAEMHTL"
     aSDomain        32366..33283
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="8.00E-87"
                     /label="puwE_Condensation_LCL.1"
                     /locus_tag="puwE"
                     /protein_end="2316"
                     /protein_start="2010"
                     /score="282.8"
                     /tool="antismash"
                     /translation="PIPLTEAQKQLWVLAQMGDDGSIAYNESVSQQLRGSLNLVAMNQA
                     IQQLVERHEALRTTISPQGDVQKILPELKLDLAVIDFSELTNSDGLRPAGSDRTSQVTA
                     WLTQESQSPFDLSSGPLFRVHLLKLEAKLHLLVLSAHHIIVDGWSLGVILQELSALYSA
                     ACQGVDCQLKPPMQFRQYIEWQTQQSQTAEMAEHEAYWLQQFANSIPVLDLPCDRTRSP
                     IKTYQGSKQSIILDASLSRAIKRVSTEQGATLFMTLLSVYTALLHRLTGQDEIVVGIPT
                     SGRSLEGSEGLVGYCAHVLPIRSSV"
     aSModule        32366..35494
                     /complete
                     /domains="nrpspksdomains_puwE_Condensation_LCL.1"
                     /domains="nrpspksdomains_puwE_AMP-binding.1"
                     /domains="nrpspksdomains_puwE_PCP.1"
                     /locus_tags="puwE"
                     /monomer_pairings="Val -> Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       32435..32545
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0010"
                     /evalue="5.10E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwE"
                     /protein_end="2070"
                     /protein_start="2033"
                     /score="47.8"
                     /tool="antismash"
                     /translation="AYNESVSQQLRGSLNLVAMNQAIQQLVERHEALRTTI"
     CDS_motif       32786..32848
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0011"
                     /evalue="3.40E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="puwE"
                     /protein_end="2171"
                     /protein_start="2150"
                     /score="35.5"
                     /tool="antismash"
                     /translation="HHIIVDGWSLGVILQELSALY"
     CDS_motif       33185..33274
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0012"
                     /evalue="4.70E-07"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwE"
                     /protein_end="2313"
                     /protein_start="2283"
                     /score="22.3"
                     /tool="antismash"
                     /translation="EIVVGIPTSGRSLEGSEGLVGYCAHVLPIR"
     CDS_motif       33323..33442
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0013"
                     /evalue="1.60E-17"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="puwE"
                     /protein_end="2369"
                     /protein_start="2329"
                     /score="55.8"
                     /tool="antismash"
                     /translation="RDVLLDAYKHQDYPFAKLIQALNLTRDASRSPLVATTFNL"
     aSDomain        33776..34966
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_AMP-binding.1"
                     /evalue="9.30E-117"
                     /label="puwE_AMP-binding.1"
                     /locus_tag="puwE"
                     /protein_end="2877"
                     /protein_start="2480"
                     /score="381.9"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEVQVQKTPDAVALLWEDQQLTYAQLNVRANQLAHYLRKQGVGPD
                     VPVGICMERSIDLVVGLLGILKAGGAYVPLDPDYPQERLSWILEDVKPLVLLTQSRLVN
                     QLPRTKIVCLDAETATIAQESTENLVPEVKADHLAYIMYTSGSTGKPKGVSIIHRGVVR
                     LVQATNYVALTAAEVFLQLAPISFDASTFEIWGSLLNGAKLVIMPIPKGTLEELGQVIR
                     ENQVTTIWLTASLFHLMVDERLDDLKSVRQLLAGGDVLSVTHVQKVFQHLPHCRLINGY
                     GPTENTTFTCCFPMTAETQIGASVPIGRPIANTLVYILDANLQPVPIGVWGELYIGGAG
                     LAQGYFNRPDLTQEKFIANPFEDSKFNRLYKTGDLARYLPDGNIEFLGRIDQQVKIR"
     CDS_motif       33962..34003
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0014"
                     /evalue="1.00E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="puwE"
                     /protein_end="2556"
                     /protein_start="2542"
                     /score="18.6"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       34190..34249
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0015"
                     /evalue="1.40E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="puwE"
                     /protein_end="2638"
                     /protein_start="2618"
                     /score="26.9"
                     /tool="antismash"
                     /translation="AYIMYTSGSTGKPKGVSIIH"
     CDS_motif       34754..34843
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0016"
                     /evalue="4.10E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="puwE"
                     /protein_end="2836"
                     /protein_start="2806"
                     /score="54.2"
                     /tool="antismash"
                     /translation="PIGVWGELYIGGAGLAQGYFNRPDLTQEKF"
     CDS_motif       34931..34993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwE_0017"
                     /evalue="2.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="puwE"
                     /protein_end="2886"
                     /protein_start="2865"
                     /score="35.7"
                     /tool="antismash"
                     /translation="FLGRIDQQVKIRGFRIELGEI"
     aSDomain        35291..35494
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwE_PCP.1"
                     /evalue="4.40E-25"
                     /label="puwE_PCP.1"
                     /locus_tag="puwE"
                     /protein_end="3053"
                     /protein_start="2985"
                     /score="79.6"
                     /tool="antismash"
                     /translation="EQAIANIVAEVLNIEQVGIDDNFFELGGNSLNANQVISRLRQTFR
                     VELPLRNLLEEPTVVELATSMDQ"
     gene            35566..42678
                     /gene="puwF"
     CDS             35566..42678
                     /NRPS_PKS="Domain: Condensation_LCL (76-375). E-value:
                     4.5e-122. Score: 398.6. Matches aSDomain:
                     nrpspksdomains_puwF_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (540-948). E-value:
                     7.1e-119. Score: 388.9. Matches aSDomain:
                     nrpspksdomains_puwF_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1058-1123). E-value: 2.8e-23.
                     Score: 73.8. Matches aSDomain: nrpspksdomains_puwF_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (1151-1451). E-value:
                     2.9e-68. Score: 222.0. Matches aSDomain:
                     nrpspksdomains_puwF_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1613-2013). E-value:
                     4.8e-114. Score: 373.0. Matches aSDomain:
                     nrpspksdomains_puwF_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2121-2188). E-value: 2.7e-23.
                     Score: 73.8. Matches aSDomain: nrpspksdomains_puwF_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (2209-2368). E-value:
                     4.4e-56. Score: 181.9. Matches aSDomain:
                     nrpspksdomains_puwF_Condensation_LCL.2"
                     /codon_start=1
                     /gene="puwF"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     361.8; E-value: 7.9e-110)"
                     /gene_kind="biosynthetic"
                     /note="non-ribosomal peptide synthetase"
                     /product="PuwF"
                     /protein_id="AIW82283.1"
                     /sec_met_domain="Condensation (E-value: 9.6e-87, bitscore:
                     280.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.5e-129, bitscore:
                     420.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.9e-16, bitscore:
                     48.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPIQEFLSELGNLNIKLWVEGGVKLRCNAPSGTLTPEIRTQLSD
                     RKAEIITFLQQVNLDADDLLDSIPVVPRDGILPLSSTQQRLWFLDQMEGASATYNMPAA
                     IEMHGILQIEMLERSLVEIVRRHEVLRTSFQQLNGTSTQVISAEATIILPVVDLQKFPP
                     EEQANEVKGLIIQEAEKPFDLKQAPLLRVTLLRLSEKSHVLLLNMHHIVSDGWSIGIFI
                     QELSALYSAYCAGKPSPLAELPIQYADFAQWQQQWLRGEVLDTKLKYWKQQLADAPPLL
                     ELPTDRPRPAIQTFRGSSREFLLPIELTEKLKRLSQQSGVTLFMTLEAAFVTLLHRYSG
                     QEDILIGTPIANRNQREIESLIGFFVNTLVLRTNLAGNPSFAELLKQVRQVALDAYTHQ
                     DVPFEQVVEALQPARNLSHTPLFQVLFALQNAPVGELELPGLRLKPLPIEAVTSKFDIT
                     LSMEETPQGLLGNWEYSTDLFDGETISRMAGHFQNLLAAVVANPAEPIQQLPLLSDSER
                     QQLLVDWNSTTVDYQTNLCLHQWFEQQVQQTPLAVAVVFDNTNLTYSQLNNRANQLAHY
                     LQTLGVAPDVLVGICVERSLEMLVGLLGILKAGGAYVPLDPEYPQERLDYMLRDSQVSV
                     LLTQSQCLKSLPDVDNLRICLDTDWEIIETQSQENPVSEVDPNNLAYIIYTSGSTGKPK
                     GVLVNHKNVTRLLGATQHWFNFNQSDVWTLFHSYAFDFSVWEIWGALLYGGRLVVVPFW
                     VSRDSNAFYNLLCVEQVTVLNQTPSAFRQLIWVEEQEERATSNLKLRWVVFGGEALDPS
                     SLIPWFKRHGDSIPQLVNMYGITETTVHVTYRPISIADTESRSSVIGAAIPDLQMYILD
                     EQLQPVPIGVRGQMYVGGAGVARGYLNRPELTAERFIKNPFRDDSEARLYKTGDLARSK
                     PDGSIEYLGRIDNQVKLRGFRIELGEIESAIAQHPQIRETVVLVREDIPGDKRLVAYFV
                     PNAEAPTSSGMRDYLKQQLPDYMIPAVFVGLDSFPLTNNGKLDVRALPIPDQSRPELET
                     YIPPSTPEQALLAGVWAEVLGAEKVGINDNYFELGGDSIRSIQIRAKANQVGLDFSLQQ
                     LFQYQTIAELASVVSREVSIAPISKTAPFSLIAAEERLKLPEDVEDAYPLAALQAGMIF
                     HSEYNETSPIYHDVFTFHLCAALDLERFNAAIQQIIARHAVLRTSIALTGFEQPLQLVH
                     QTVETPLQVEDISLMSKDQQEAVIDAWMEAEKNRHFDWKIPPLLRFHIHRRSEETFNLS
                     FSFHHAILDGWSVASLLTELLQKYFSLMGQEVVLQPSPNLAFADFIALEQTTLQSQDSQ
                     QYWTEQLSDLNVISLPRLPESKSAAKGQLGVQEVPISPEISAGLKQLAQNAGVPIKSVL
                     LAAHLRVLSLVSNQTDVLTGLVSNGRPENADGERVLGLFLNTLPLRLHLNGGTWLDLIR
                     ETFQAEQGILPHRRYPLAELQKMCGGKSLFETNFNFVHFHVYQSILGLEGLEVLGHKVF
                     EQTNFTLVANFSLDLISSQINCILNYDAIELGEEQVRAIGGYYGKTLEAMVSQPDERYE
                     LRSLLSDSERHTLLVEWNQTSSDYPAHLCLHQLIEQQVQRTPDAVAVVFADQHLTYSQL
                     NNRANQLAHHLQSLGVAPDVLVGICVERSLEMLVGLLGIMKAGGAYVPIDPAYPQERLR
                     YMLGDAQVSVLLTQSHLLDILPEENPILCLDTDWQIIAHQSCENVVSQVQPQNLAYIIY
                     TSGSTGQPKGAMIQHQGLVNYLYWSIEAYAVADGCGAPVNSSFAFDATITCLFTPLMVG
                     GQVMMLPEQQKIEALCDVLRGRHQFSLVKLTPAHLELLNQLLLPEELPESALALVIGGE
                     ALLGKTLQFWQQYAPNTRLINEYGPTETVVGCSIYEVTPETSLTEGILIGRPIANTQLY
                     ILDKFLQPVPIGVGGELYIGGAGVARGYFNRPELTQEKFIPNPFSKNREARLYKTGDLA
                     RYLPDGNIEYLGRIDNQVKLRGFRIELGEIENALAQHPQVRETAVLLREDIPGDKRLIA
                     YFVADTEAPTSSDLRDYLKKRLPDYMIPAGFVELETFPLTNNGKVDRRALPAPDLETSN
                     SSNLVSPRTPTEEIIANIIAEVLRVKNLSIYDNFFEIGGNSLLATQVITRLRETFQIEL
                     PLRYLFESPTVAELDAAITTFRQTASGLSTPELTAINRENQPLSLSWAQQRLWFIDQLE
                     GASAVYNMPAAVQMDGILQIEVLEQSLAEIVRRHEVLRTSFHQLNGTSVQVISSEATIN
                     LPVVDLQGESTTEVQKLITLAAEKPFDLKQAPLLRVTLLRLGEKSHLLLLNMHHIVSDG
                     WSTGIFIQELSALYSAYCAGKPHH"
     aSDomain        35794..36690
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.50E-122"
                     /label="puwF_Condensation_LCL.1"
                     /locus_tag="puwF"
                     /protein_end="375"
                     /protein_start="76"
                     /score="398.6"
                     /tool="antismash"
                     /translation="LPLSSTQQRLWFLDQMEGASATYNMPAAIEMHGILQIEMLERSLV
                     EIVRRHEVLRTSFQQLNGTSTQVISAEATIILPVVDLQKFPPEEQANEVKGLIIQEAEK
                     PFDLKQAPLLRVTLLRLSEKSHVLLLNMHHIVSDGWSIGIFIQELSALYSAYCAGKPSP
                     LAELPIQYADFAQWQQQWLRGEVLDTKLKYWKQQLADAPPLLELPTDRPRPAIQTFRGS
                     SREFLLPIELTEKLKRLSQQSGVTLFMTLEAAFVTLLHRYSGQEDILIGTPIANRNQRE
                     IESLIGFFVNTLVLRTNL"
     aSModule        35794..38934
                     /complete
                     /domains="nrpspksdomains_puwF_Condensation_LCL.1"
                     /domains="nrpspksdomains_puwF_AMP-binding.1"
                     /domains="nrpspksdomains_puwF_PCP.1"
                     /locus_tags="puwF"
                     /monomer_pairings="Thr -> Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       35803..35835
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0001"
                     /evalue="5.70E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="puwF"
                     /protein_end="90"
                     /protein_start="79"
                     /score="6.6"
                     /tool="antismash"
                     /translation="SSTQQRLWFLD"
     CDS_motif       35854..35967
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0002"
                     /evalue="1.30E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwF"
                     /protein_end="134"
                     /protein_start="96"
                     /score="49.7"
                     /tool="antismash"
                     /translation="ATYNMPAAIEMHGILQIEMLERSLVEIVRRHEVLRTSF"
     CDS_motif       36187..36252
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0003"
                     /evalue="1.10E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="puwF"
                     /protein_end="229"
                     /protein_start="207"
                     /score="40.2"
                     /tool="antismash"
                     /translation="MHHIVSDGWSIGIFIQELSALY"
     CDS_motif       36301..36339
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0004"
                     /evalue="3.90E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="puwF"
                     /protein_end="258"
                     /protein_start="245"
                     /score="13.1"
                     /tool="antismash"
                     /translation="QYADFAQWQQQWL"
     CDS_motif       36592..36681
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0005"
                     /evalue="2.90E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwF"
                     /protein_end="372"
                     /protein_start="342"
                     /score="54.9"
                     /tool="antismash"
                     /translation="DILIGTPIANRNQREIESLIGFFVNTLVLR"
     CDS_motif       36730..36849
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0006"
                     /evalue="5.40E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="puwF"
                     /protein_end="428"
                     /protein_start="388"
                     /score="76.7"
                     /tool="antismash"
                     /translation="RQVALDAYTHQDVPFEQVVEALQPARNLSHTPLFQVLFAL"
     aSDomain        37186..38409
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_AMP-binding.1"
                     /evalue="7.10E-119"
                     /label="puwF_AMP-binding.1"
                     /locus_tag="puwF"
                     /protein_end="948"
                     /protein_start="540"
                     /score="388.9"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEQQVQQTPLAVAVVFDNTNLTYSQLNNRANQLAHYLQTLGVAPD
                     VLVGICVERSLEMLVGLLGILKAGGAYVPLDPEYPQERLDYMLRDSQVSVLLTQSQCLK
                     SLPDVDNLRICLDTDWEIIETQSQENPVSEVDPNNLAYIIYTSGSTGKPKGVLVNHKNV
                     TRLLGATQHWFNFNQSDVWTLFHSYAFDFSVWEIWGALLYGGRLVVVPFWVSRDSNAFY
                     NLLCVEQVTVLNQTPSAFRQLIWVEEQEERATSNLKLRWVVFGGEALDPSSLIPWFKRH
                     GDSIPQLVNMYGITETTVHVTYRPISIADTESRSSVIGAAIPDLQMYILDEQLQPVPIG
                     VRGQMYVGGAGVARGYLNRPELTAERFIKNPFRDDSEARLYKTGDLARSKPDGSIEYLG
                     RIDNQVKLR"
     CDS_motif       37372..37413
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0007"
                     /evalue="7.60E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="puwF"
                     /protein_end="616"
                     /protein_start="602"
                     /score="19.0"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       37606..37665
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0008"
                     /evalue="3.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="puwF"
                     /protein_end="700"
                     /protein_start="680"
                     /score="31.7"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVLVNH"
     CDS_motif       38197..38286
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0009"
                     /evalue="7.40E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="puwF"
                     /protein_end="907"
                     /protein_start="877"
                     /score="53.4"
                     /tool="antismash"
                     /translation="PIGVRGQMYVGGAGVARGYLNRPELTAERF"
     CDS_motif       38374..38439
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0010"
                     /evalue="5.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwF"
                     /protein_end="958"
                     /protein_start="936"
                     /score="37.6"
                     /tool="antismash"
                     /translation="YLGRIDNQVKLRGFRIELGEIE"
     CDS_motif       38479..38532
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0011"
                     /evalue="1.70E+01"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwF"
                     /protein_end="989"
                     /protein_start="971"
                     /score="-1.9"
                     /tool="antismash"
                     /translation="VLVREDIPGDKRLVAYFV"
     aSDomain        38740..38934
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_PCP.1"
                     /evalue="2.80E-23"
                     /label="puwF_PCP.1"
                     /locus_tag="puwF"
                     /protein_end="1123"
                     /protein_start="1058"
                     /score="73.8"
                     /tool="antismash"
                     /translation="LLAGVWAEVLGAEKVGINDNYFELGGDSIRSIQIRAKANQVGLDF
                     SLQQLFQYQTIAELASVVSR"
     aSDomain        39019..39918
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.90E-68"
                     /label="puwF_Condensation_DCL.1"
                     /locus_tag="puwF"
                     /protein_end="1451"
                     /protein_start="1151"
                     /score="222.0"
                     /tool="antismash"
                     /translation="EDAYPLAALQAGMIFHSEYNETSPIYHDVFTFHLCAALDLERFNA
                     AIQQIIARHAVLRTSIALTGFEQPLQLVHQTVETPLQVEDISLMSKDQQEAVIDAWMEA
                     EKNRHFDWKIPPLLRFHIHRRSEETFNLSFSFHHAILDGWSVASLLTELLQKYFSLMGQ
                     EVVLQPSPNLAFADFIALEQTTLQSQDSQQYWTEQLSDLNVISLPRLPESKSAAKGQLG
                     VQEVPISPEISAGLKQLAQNAGVPIKSVLLAAHLRVLSLVSNQTDVLTGLVSNGRPENA
                     DGERVLGLFLNTLPLRLHL"
     aSModule        39019..42129
                     /complete
                     /domains="nrpspksdomains_puwF_Condensation_DCL.1"
                     /domains="nrpspksdomains_puwF_AMP-binding.2"
                     /domains="nrpspksdomains_puwF_PCP.2"
                     /locus_tags="puwF"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       39028..39066
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0012"
                     /evalue="3.30E-03"
                     /label="C1_dual_004-017"
                     /locus_tag="puwF"
                     /protein_end="1167"
                     /protein_start="1154"
                     /score="10.6"
                     /tool="antismash"
                     /translation="YPLAALQAGMIFH"
     CDS_motif       39088..39201
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0013"
                     /evalue="9.90E-11"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwF"
                     /protein_end="1212"
                     /protein_start="1174"
                     /score="34.0"
                     /tool="antismash"
                     /translation="PIYHDVFTFHLCAALDLERFNAAIQQIIARHAVLRTSI"
     CDS_motif       39424..39489
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0014"
                     /evalue="4.10E-08"
                     /label="C3_DCL_135-156"
                     /locus_tag="puwF"
                     /protein_end="1308"
                     /protein_start="1286"
                     /score="25.8"
                     /tool="antismash"
                     /translation="FHHAILDGWSVASLLTELLQKY"
     CDS_motif       39817..39909
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0015"
                     /evalue="1.80E-07"
                     /label="C5_DCL_263-294"
                     /locus_tag="puwF"
                     /protein_end="1448"
                     /protein_start="1417"
                     /score="23.6"
                     /tool="antismash"
                     /translation="DVLTGLVSNGRPENADGERVLGLFLNTLPLR"
     aSDomain        40405..41604
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_AMP-binding.2"
                     /evalue="4.80E-114"
                     /label="puwF_AMP-binding.2"
                     /locus_tag="puwF"
                     /protein_end="2013"
                     /protein_start="1613"
                     /score="373.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EQQVQRTPDAVAVVFADQHLTYSQLNNRANQLAHHLQSLGVAPDV
                     LVGICVERSLEMLVGLLGIMKAGGAYVPIDPAYPQERLRYMLGDAQVSVLLTQSHLLDI
                     LPEENPILCLDTDWQIIAHQSCENVVSQVQPQNLAYIIYTSGSTGQPKGAMIQHQGLVN
                     YLYWSIEAYAVADGCGAPVNSSFAFDATITCLFTPLMVGGQVMMLPEQQKIEALCDVLR
                     GRHQFSLVKLTPAHLELLNQLLLPEELPESALALVIGGEALLGKTLQFWQQYAPNTRLI
                     NEYGPTETVVGCSIYEVTPETSLTEGILIGRPIANTQLYILDKFLQPVPIGVGGELYIG
                     GAGVARGYFNRPELTQEKFIPNPFSKNREARLYKTGDLARYLPDGNIEYLGRIDNQVKL
                     R"
     CDS_motif       40588..40629
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0016"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="puwF"
                     /protein_end="1688"
                     /protein_start="1674"
                     /score="18.5"
                     /tool="antismash"
                     /translation="LGIMKAGGAYVPID"
     CDS_motif       40819..40878
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0017"
                     /evalue="7.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="puwF"
                     /protein_end="1771"
                     /protein_start="1751"
                     /score="30.7"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGQPKGAMIQH"
     CDS_motif       41392..41481
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0018"
                     /evalue="4.40E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="puwF"
                     /protein_end="1972"
                     /protein_start="1942"
                     /score="54.1"
                     /tool="antismash"
                     /translation="PIGVGGELYIGGAGVARGYFNRPELTQEKF"
     CDS_motif       41569..41634
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0019"
                     /evalue="5.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwF"
                     /protein_end="2023"
                     /protein_start="2001"
                     /score="37.6"
                     /tool="antismash"
                     /translation="YLGRIDNQVKLRGFRIELGEIE"
     CDS_motif       41674..41727
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0020"
                     /evalue="1.10E+01"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwF"
                     /protein_end="2054"
                     /protein_start="2036"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="VLLREDIPGDKRLIAYFV"
     aSDomain        41929..42129
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_PCP.2"
                     /evalue="2.70E-23"
                     /label="puwF_PCP.2"
                     /locus_tag="puwF"
                     /protein_end="2188"
                     /protein_start="2121"
                     /score="73.8"
                     /tool="antismash"
                     /translation="EEIIANIIAEVLRVKNLSIYDNFFEIGGNSLLATQVITRLRETFQ
                     IELPLRYLFESPTVAELDAAIT"
     aSDomain        42193..42669
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwF_Condensation_LCL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="4.40E-56"
                     /label="puwF_Condensation_LCL.2"
                     /locus_tag="puwF"
                     /protein_end="2368"
                     /protein_start="2209"
                     /score="181.9"
                     /tool="antismash"
                     /translation="QPLSLSWAQQRLWFIDQLEGASAVYNMPAAVQMDGILQIEVLEQS
                     LAEIVRRHEVLRTSFHQLNGTSVQVISSEATINLPVVDLQGESTTEVQKLITLAAEKPF
                     DLKQAPLLRVTLLRLGEKSHLLLLNMHHIVSDGWSTGIFIQELSALYSAYCAGKP"
     CDS_motif       42208..42237
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0021"
                     /evalue="3.80E-02"
                     /label="C1_LCL_004-017"
                     /locus_tag="puwF"
                     /protein_end="2224"
                     /protein_start="2214"
                     /score="7.1"
                     /tool="antismash"
                     /translation="SWAQQRLWFI"
     CDS_motif       42259..42375
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0022"
                     /evalue="9.70E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwF"
                     /protein_end="2270"
                     /protein_start="2231"
                     /score="53.4"
                     /tool="antismash"
                     /translation="AVYNMPAAVQMDGILQIEVLEQSLAEIVRRHEVLRTSFH"
     CDS_motif       42580..42645
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwF_0023"
                     /evalue="1.00E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="puwF"
                     /protein_end="2360"
                     /protein_start="2338"
                     /score="40.4"
                     /tool="antismash"
                     /translation="MHHIVSDGWSTGIFIQELSALY"
     gene            42729..53207
                     /gene="puwG"
     CDS             42729..53207
                     /NRPS_PKS="Domain: AMP-binding (283-691). E-value:
                     1.1e-118. Score: 388.2. Matches aSDomain:
                     nrpspksdomains_puwG_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (799-865). E-value: 2.8e-23. Score:
                     73.8. Matches aSDomain: nrpspksdomains_puwG_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (893-1194). E-value:
                     1.8e-68. Score: 222.7. Matches aSDomain:
                     nrpspksdomains_puwG_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1355-1785). E-value:
                     2e-114. Score: 374.2. Matches aSDomain:
                     nrpspksdomains_puwG_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1892-1959). E-value: 5.7e-24.
                     Score: 76.0. Matches aSDomain: nrpspksdomains_puwG_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (1980-2277). E-value:
                     2.6e-123. Score: 402.6. Matches aSDomain:
                     nrpspksdomains_puwG_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (2442-2835). E-value:
                     2.6e-115. Score: 377.2. Matches aSDomain:
                     nrpspksdomains_puwG_AMP-binding.3"
                     /NRPS_PKS="Domain: PCP (2943-3007). E-value: 8.5e-25.
                     Score: 78.7. Matches aSDomain: nrpspksdomains_puwG_PCP.3"
                     /NRPS_PKS="Domain: Epimerization (3020-3326). E-value:
                     8e-165. Score: 541.5. Matches aSDomain:
                     nrpspksdomains_puwG_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (3332-3487). E-value: 9.5e-49.
                     Score: 157.0. Matches aSDomain:
                     nrpspksdomains_puwG_TIGR01720.1"
                     /NRPS_PKS="Domain: NRPS-COM_Cterm (3470-3491). E-value:
                     1.5e-08. Score: 26.2. Matches aSDomain:
                     nrpspksdomains_puwG_NRPS-COM_Cterm.1"
                     /codon_start=1
                     /gene="puwG"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     361.6; E-value: 9.1e-110)"
                     /gene_kind="biosynthetic"
                     /note="non-ribosomal peptide synthetase"
                     /product="PuwG"
                     /protein_id="AIW82284.1"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-129, bitscore:
                     421.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.5e-17, bitscore:
                     52.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.7e-85, bitscore:
                     275.0, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGEVLDTKLKYWKQQLADAPPLLELPTDRPRPAIQTFRGSSRDF
                     LLPIELTEKLKRLSQQSGVTLFMTLEAAFVSLLHRYSGQEDILIGTPIANRNQREIESL
                     IGFFVNTLVLRTNLAGNPSFAELLKQVRQVALDAYTHQDVPFEQVVEALQPARNLSHTP
                     LFQVLFALQNAPVGELELPGLRLKPLPIEAVASKFDITLSMEETPQGLLGNWEYSTDLF
                     DGETISRMAGHFQNLLTAIVANPAETIQQLPLLSNSERQQLLVDWNSTTVDYQTNLCLH
                     QWFEQQVQQTPLAVAVVFDNTNLTYSQLNNRANQLAHYLQTLGVAPDVLVGICVERSLD
                     MVVGLLGILKAGGAYVPLDPEYPQERLEFMLDDSQVSVLLTQSQCLKSLPEVQAQIIPL
                     DTDWEIIETQSQENPVSEVDPNNLAYIIYTSGSTGKPKGVLVNHKNVTRLLGATQHWFN
                     FNQSDVWTLFHSYAFDFSVWEIWGALLYGGRLVVVPFWVSRDSNAFYNLLCVEQVTVLN
                     QTPSAFRQLIWVEEQEERATSNLKLRWVVFGGEALDPSSLIPWFKRHGDSIPQLVNMYG
                     ITETTVHVTYRPISIADTESRSSVIGAAIPDLQMYILDEQLQPVPIGVRGQMYVGGAGV
                     ARGYLNRPELTAERFIKNPFRDDSEARLYKTGDLARSKPDGSIEYLGRIDNQVKLRGFR
                     IELGEIESAIAQHPQIRETVVLVREDIPGDKRLVAYFVPNAEAPTSSGMRDYLKQQLPD
                     YMIPAVFVGLDSFPLTANGKLDVRALPIPEQSKPEETYIPPSTPEQTLLAGVWAEVLGA
                     EKVGINDNYFELGGDSIRSIQIKAKANQVGLDFSLQQLFQYQTIAELASVVSSQPNIFP
                     IPSSKPFSLISDTDQLKLPEDVEDAYPLAALQAGMIFHSEYSIDTAIYHDVFSFHLRAI
                     LDIAKFKDAIQQVVNRYAVLRTSFALTGYEQPLQLVHQTVETPLQVEDISHLDISAQKA
                     VIDDWITAEKYRHFDWKIAPMLRFQIHRRSGETFSLSFSFHHAILDGWSVASLLTELWQ
                     QYFSLLGHTVALQPSPTTTFRDFVALEQSALQSQDSQQYWTEQLRDFNVTELPRLPESA
                     RTGESEKLGEREVLISPELSEGLKQLARKAGVPIKSVLLAAHLRVLSLVSNQTDVLTGL
                     VSNGRPENVDGERALGLFLNTLPLRLHLNGGTWLDLVRATFQAEQANIPHRRYPLAEMQ
                     RMCGGQSLFETNFNFTHFHVYQGILGLDGLELIENTLFEQTNFALVANFSLDVSSSDVR
                     LILSYDAIELGESQIKAIGSYYGKTLEAMVSQPDERYEMRSLLSDSERHQLLVEWNDTQ
                     ADYPAHLCLHQLFEQQVQRTPDAVAVVFADQHLTYSQLNNRANQLGHYLQSLGVAPDVL
                     VGICVERSLEMLVGLLGILKAGGAYVPLDPAYPQERLRYMLDDSQVSVLLTQSHLLDIL
                     PEGNSIFCLDTDWQLIAQQGTENVSSLGTRYEEIGVLRTAKTPRTPRNERRCVSPEVES
                     SNLAYIIYTSGSTGQPKGTMIQHQGVVNYLSWCTQAYAIADGCGAPVQSSFAFDATITS
                     IFSPLIVGGQVVLLPEKQEIEALCEVLRGRHQFSLVKLTPAHLELLNQLLLPEELPESA
                     QALVIGGEALLGKTLQFWQQYAPNTRLINEYGPTETVVGCCIYEVTPETSLTEKILIGR
                     PIANTQLYILDSHLQPLPIGVGGELYIGGAGVARGYLNRPELTAERFIRNPFRNDPEAR
                     LYKTGDLARYLPDGNIEYLGRIDNQIKLRGFRIELGEIENALAQHPQVRETAVLLREDI
                     SGDKRLIAYFVADTEAPTSSDLRDYLKKQLPDYMIPAGFVGLETFPLTANGKVDRRALK
                     APDLETSSSNFVSPRTPTEEIIANIIAEVLRVKRISIHDNFFEIGGNSLNATQVITRLR
                     ETFQIELPLRYLFESPTVAELDTAITTFRQTASGLSTPALVPAKRENQPLSLSWAQQRL
                     WFIDQLEGASAVYNIPASVQMDGILDVVALEQTLAEIVRRHEILRTSFHQLNGTSVQVI
                     SAEATINLPVVDLQGEPTTEVQRLITLAAEKPFDLKQAPLLRVTLLRLGEKSHVLLLNM
                     HHIVSDGWSTGIFIQELSALYSAYCEGKPSPLTELPIQYADFAQWQQQWLRGEVLDTKL
                     KYWKQQLADAPPLLELPTDRPRPAIQTFRGSSREFLLPIELTEKLKRLSQQSGVTLFMT
                     LEAAFVTLLHRYSGQEDILIGTPIANRNHREIESLIGFFVNTLVLRTNLAGNPSFAELL
                     KQVRQVALDAYTHQDVPFEQVVEALQPARNLSHTPLFQVMFILQNAPMGDLELPGLHLT
                     PLSMGAVSAKFDLTLSMEETPQGLLGNWEYSTDLFDGETISRMAGHFQNLLAAVVANPA
                     ETIQQLPLLSDSERQQLLVDWNSTTVDYQHHLCLHQWFEQQVQQTPDALAVVFDNTSLT
                     YSQLNNRANQLAHYLQTLGVAPDVLVGICVERSLDMVVGILGILKAGGAYVPLDPEYPQ
                     ERLDYMLRDSQVSVLLTQSQCLKSLPDVDNLRICLDTDWGIIETQSQENPVSEVAPNNL
                     AYIIYTSGSTGKPKGVAIAHCSPVALVAWALKVFTPQQLAGVLASTSLCFDLSIFEMFV
                     PLSCGGMVIVAENALHLPELIAFEQVTLINTVPSAIRELLNGPGLPQSLATVNLAGEPL
                     PLSLVQQLYQRQTIHQVFNLYGPSETTTYSTFALCNRGDSLAPTIGRAIANTQIYILDA
                     LMQPVPIGVRGELYIGGAGVARGYLNRPELTAEKFIPNPFENSKFHRLYKTGDLARYLP
                     DGNIEYLGRIDNQVKLRGFRIELGEIETAIALHPQLKQAVVSIREDQPGIRRLVAYLVA
                     EVETPSSSELRSFLKQQLPDYMVPGIFVFLDALPLTPNGKVDRRALPAPNLEQNRPISL
                     VPASTAIEESLVTIWSEILGLKQVSIHDNFFDLGGDSIISIQIIARAAQVGVQLTLKQI
                     FQYQTIAELATVCGTITVQAEQGLVTGEVPLTPIQQWFLEQNSPHPDYFNQSVLLEVAP
                     DLKPELLQQVVQQLLEQHDALRLRFGRNDSQWQQINSDTSDIVPFQVFDLSALAHEAQQ
                     AAIETTAAQLQGSLNLSEGPLMRVALFKLGSDSLDQLLIIIHHLAVDGVSWRILLADLS
                     TAYQQISRGEAIQLPLKTTSFKDWAIRLQDYGRSPSLAAELDYWLASSRANVAPLPVDY
                     PDGKESNTVGNTAQVSVSLSESLTHALLQEVPQAYNTQINDVLLTALLQSFAPWTGANS
                     VLVDLEGHGREELFEEINLSRTVGWFTTIYPLLLELGEENQPGAALKWVKEQLRTVPQR
                     GIGYGVLRYLSGDSNIRQQLQALPQAEVCFNYLGQFDHLQTEGIIQGFSQASSGATQSP
                     LSHRRYLLEVNGLVAEGKLQLNWTYSKVVHERRTIERLANEFITVLQGLIIHCQSPEAG
                     GFTPSDFPIAELSQADLDELLAEIN"
     CDS_motif       42984..43073
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0001"
                     /evalue="4.50E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwG"
                     /protein_end="115"
                     /protein_start="85"
                     /score="54.3"
                     /tool="antismash"
                     /translation="DILIGTPIANRNQREIESLIGFFVNTLVLR"
     CDS_motif       43122..43241
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0002"
                     /evalue="8.10E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="puwG"
                     /protein_end="171"
                     /protein_start="131"
                     /score="76.1"
                     /tool="antismash"
                     /translation="RQVALDAYTHQDVPFEQVVEALQPARNLSHTPLFQVLFAL"
     aSDomain        43578..44801
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_AMP-binding.1"
                     /evalue="1.10E-118"
                     /label="puwG_AMP-binding.1"
                     /locus_tag="puwG"
                     /protein_end="691"
                     /protein_start="283"
                     /score="388.2"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEQQVQQTPLAVAVVFDNTNLTYSQLNNRANQLAHYLQTLGVAPD
                     VLVGICVERSLDMVVGLLGILKAGGAYVPLDPEYPQERLEFMLDDSQVSVLLTQSQCLK
                     SLPEVQAQIIPLDTDWEIIETQSQENPVSEVDPNNLAYIIYTSGSTGKPKGVLVNHKNV
                     TRLLGATQHWFNFNQSDVWTLFHSYAFDFSVWEIWGALLYGGRLVVVPFWVSRDSNAFY
                     NLLCVEQVTVLNQTPSAFRQLIWVEEQEERATSNLKLRWVVFGGEALDPSSLIPWFKRH
                     GDSIPQLVNMYGITETTVHVTYRPISIADTESRSSVIGAAIPDLQMYILDEQLQPVPIG
                     VRGQMYVGGAGVARGYLNRPELTAERFIKNPFRDDSEARLYKTGDLARSKPDGSIEYLG
                     RIDNQVKLR"
     aSModule        43578..45323
                     /complete
                     /domains="nrpspksdomains_puwG_AMP-binding.1"
                     /domains="nrpspksdomains_puwG_PCP.1"
                     /locus_tags="puwG"
                     /monomer_pairings="Thr -> Thr"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       43764..43805
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0003"
                     /evalue="1.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="puwG"
                     /protein_end="359"
                     /protein_start="345"
                     /score="18.4"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       43998..44057
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0004"
                     /evalue="5.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="puwG"
                     /protein_end="443"
                     /protein_start="423"
                     /score="31.1"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVLVNH"
     CDS_motif       44451..44474
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0005"
                     /evalue="3.60E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="puwG"
                     /protein_end="582"
                     /protein_start="574"
                     /score="1.6"
                     /tool="antismash"
                     /translation="YGITETTV"
     CDS_motif       44589..44678
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0006"
                     /evalue="1.10E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="puwG"
                     /protein_end="650"
                     /protein_start="620"
                     /score="52.8"
                     /tool="antismash"
                     /translation="PIGVRGQMYVGGAGVARGYLNRPELTAERF"
     CDS_motif       44766..44831
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0007"
                     /evalue="8.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwG"
                     /protein_end="701"
                     /protein_start="679"
                     /score="37.1"
                     /tool="antismash"
                     /translation="YLGRIDNQVKLRGFRIELGEIE"
     CDS_motif       44871..44924
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0008"
                     /evalue="2.60E+01"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwG"
                     /protein_end="732"
                     /protein_start="714"
                     /score="-2.5"
                     /tool="antismash"
                     /translation="VLVREDIPGDKRLVAYFV"
     CDS_motif       45042..45068
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0009"
                     /evalue="2.10E+01"
                     /label="NRPS-A_a10"
                     /locus_tag="puwG"
                     /protein_end="780"
                     /protein_start="771"
                     /score="-0.5"
                     /tool="antismash"
                     /translation="GKLDVRALP"
     aSDomain        45126..45323
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_PCP.1"
                     /evalue="2.80E-23"
                     /label="puwG_PCP.1"
                     /locus_tag="puwG"
                     /protein_end="865"
                     /protein_start="799"
                     /score="73.8"
                     /tool="antismash"
                     /translation="TLLAGVWAEVLGAEKVGINDNYFELGGDSIRSIQIKAKANQVGLD
                     FSLQQLFQYQTIAELASVVSS"
     CDS_motif       45186..45215
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0010"
                     /evalue="6.60E-01"
                     /label="PCP_mE"
                     /locus_tag="puwG"
                     /protein_end="829"
                     /protein_start="819"
                     /score="3.8"
                     /tool="antismash"
                     /translation="NYFELGGDSI"
     aSDomain        45408..46310
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.80E-68"
                     /label="puwG_Condensation_DCL.1"
                     /locus_tag="puwG"
                     /protein_end="1194"
                     /protein_start="893"
                     /score="222.7"
                     /tool="antismash"
                     /translation="EDAYPLAALQAGMIFHSEYSIDTAIYHDVFSFHLRAILDIAKFKD
                     AIQQVVNRYAVLRTSFALTGYEQPLQLVHQTVETPLQVEDISHLDISAQKAVIDDWITA
                     EKYRHFDWKIAPMLRFQIHRRSGETFSLSFSFHHAILDGWSVASLLTELWQQYFSLLGH
                     TVALQPSPTTTFRDFVALEQSALQSQDSQQYWTEQLRDFNVTELPRLPESARTGESEKL
                     GEREVLISPELSEGLKQLARKAGVPIKSVLLAAHLRVLSLVSNQTDVLTGLVSNGRPEN
                     VDGERALGLFLNTLPLRLHL"
     aSModule        45408..48605
                     /complete
                     /domains="nrpspksdomains_puwG_Condensation_DCL.1"
                     /domains="nrpspksdomains_puwG_AMP-binding.2"
                     /domains="nrpspksdomains_puwG_PCP.2"
                     /locus_tags="puwG"
                     /monomer_pairings="Asn -> Asn"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       45417..45455
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0011"
                     /evalue="5.10E-03"
                     /label="C1_dual_004-017"
                     /locus_tag="puwG"
                     /protein_end="909"
                     /protein_start="896"
                     /score="10.0"
                     /tool="antismash"
                     /translation="YPLAALQAGMIFH"
     CDS_motif       45483..45590
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0012"
                     /evalue="5.50E-10"
                     /label="C2_DCL_024-062"
                     /locus_tag="puwG"
                     /protein_end="954"
                     /protein_start="918"
                     /score="31.5"
                     /tool="antismash"
                     /translation="YHDVFSFHLRAILDIAKFKDAIQQVVNRYAVLRTSF"
     CDS_motif       45813..45878
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0013"
                     /evalue="2.60E-07"
                     /label="C3_DCL_135-156"
                     /locus_tag="puwG"
                     /protein_end="1050"
                     /protein_start="1028"
                     /score="23.2"
                     /tool="antismash"
                     /translation="FHHAILDGWSVASLLTELWQQY"
     CDS_motif       46209..46301
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0014"
                     /evalue="2.40E-06"
                     /label="C5_DCL_263-294"
                     /locus_tag="puwG"
                     /protein_end="1191"
                     /protein_start="1160"
                     /score="20.1"
                     /tool="antismash"
                     /translation="DVLTGLVSNGRPENVDGERALGLFLNTLPLR"
     aSDomain        46794..48083
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_AMP-binding.2"
                     /evalue="2.00E-114"
                     /label="puwG_AMP-binding.2"
                     /locus_tag="puwG"
                     /protein_end="1785"
                     /protein_start="1355"
                     /score="374.2"
                     /specificity="substrate consensus: Asn"
                     /tool="antismash"
                     /translation="FEQQVQRTPDAVAVVFADQHLTYSQLNNRANQLGHYLQSLGVAPD
                     VLVGICVERSLEMLVGLLGILKAGGAYVPLDPAYPQERLRYMLDDSQVSVLLTQSHLLD
                     ILPEGNSIFCLDTDWQLIAQQGTENVSSLGTRYEEIGVLRTAKTPRTPRNERRCVSPEV
                     ESSNLAYIIYTSGSTGQPKGTMIQHQGVVNYLSWCTQAYAIADGCGAPVQSSFAFDATI
                     TSIFSPLIVGGQVVLLPEKQEIEALCEVLRGRHQFSLVKLTPAHLELLNQLLLPEELPE
                     SAQALVIGGEALLGKTLQFWQQYAPNTRLINEYGPTETVVGCCIYEVTPETSLTEKILI
                     GRPIANTQLYILDSHLQPLPIGVGGELYIGGAGVARGYLNRPELTAERFIRNPFRNDPE
                     ARLYKTGDLARYLPDGNIEYLGRIDNQIKLR"
     CDS_motif       46980..47021
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0015"
                     /evalue="1.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="puwG"
                     /protein_end="1431"
                     /protein_start="1417"
                     /score="18.4"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       47298..47357
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0016"
                     /evalue="6.30E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="puwG"
                     /protein_end="1543"
                     /protein_start="1523"
                     /score="31.0"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGQPKGTMIQH"
     CDS_motif       47730..47756
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0017"
                     /evalue="6.80E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="puwG"
                     /protein_end="1676"
                     /protein_start="1667"
                     /score="3.6"
                     /tool="antismash"
                     /translation="EYGPTETVV"
     CDS_motif       47871..47960
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0018"
                     /evalue="3.40E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="puwG"
                     /protein_end="1744"
                     /protein_start="1714"
                     /score="57.6"
                     /tool="antismash"
                     /translation="PIGVGGELYIGGAGVARGYLNRPELTAERF"
     CDS_motif       48048..48113
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0019"
                     /evalue="2.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="puwG"
                     /protein_end="1795"
                     /protein_start="1773"
                     /score="35.8"
                     /tool="antismash"
                     /translation="YLGRIDNQIKLRGFRIELGEIE"
     CDS_motif       48324..48347
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0020"
                     /evalue="1.40E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="puwG"
                     /protein_end="1873"
                     /protein_start="1865"
                     /score="2.6"
                     /tool="antismash"
                     /translation="GKVDRRAL"
     aSDomain        48405..48605
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_PCP.2"
                     /evalue="5.70E-24"
                     /label="puwG_PCP.2"
                     /locus_tag="puwG"
                     /protein_end="1959"
                     /protein_start="1892"
                     /score="76.0"
                     /tool="antismash"
                     /translation="EEIIANIIAEVLRVKRISIHDNFFEIGGNSLNATQVITRLRETFQ
                     IELPLRYLFESPTVAELDTAIT"
     CDS_motif       48468..48497
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0021"
                     /evalue="1.10E+01"
                     /label="PCP_mE"
                     /locus_tag="puwG"
                     /protein_end="1923"
                     /protein_start="1913"
                     /score="0.6"
                     /tool="antismash"
                     /translation="NFFEIGGNSL"
     aSDomain        48669..49559
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="2.60E-123"
                     /label="puwG_Condensation_LCL.1"
                     /locus_tag="puwG"
                     /protein_end="2277"
                     /protein_start="1980"
                     /score="402.6"
                     /tool="antismash"
                     /translation="QPLSLSWAQQRLWFIDQLEGASAVYNIPASVQMDGILDVVALEQT
                     LAEIVRRHEILRTSFHQLNGTSVQVISAEATINLPVVDLQGEPTTEVQRLITLAAEKPF
                     DLKQAPLLRVTLLRLGEKSHVLLLNMHHIVSDGWSTGIFIQELSALYSAYCEGKPSPLT
                     ELPIQYADFAQWQQQWLRGEVLDTKLKYWKQQLADAPPLLELPTDRPRPAIQTFRGSSR
                     EFLLPIELTEKLKRLSQQSGVTLFMTLEAAFVTLLHRYSGQEDILIGTPIANRNHREIE
                     SLIGFFVNTLVLRTNL"
     aSModule        48669..53189
                     /complete
                     /domains="nrpspksdomains_puwG_Condensation_LCL.1"
                     /domains="nrpspksdomains_puwG_AMP-binding.3"
                     /domains="nrpspksdomains_puwG_PCP.3"
                     /domains="nrpspksdomains_puwG_Epimerization.1"
                     /domains="nrpspksdomains_puwG_TIGR01720.1"
                     /locus_tags="puwG"
                     /monomer_pairings="Ala -> D-Ala"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       48735..48851
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0022"
                     /evalue="5.80E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwG"
                     /protein_end="2041"
                     /protein_start="2002"
                     /score="54.1"
                     /tool="antismash"
                     /translation="AVYNIPASVQMDGILDVVALEQTLAEIVRRHEILRTSFH"
     CDS_motif       49056..49121
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0023"
                     /evalue="1.50E-12"
                     /label="C3_LCL_132-143"
                     /locus_tag="puwG"
                     /protein_end="2131"
                     /protein_start="2109"
                     /score="39.8"
                     /tool="antismash"
                     /translation="MHHIVSDGWSTGIFIQELSALY"
     CDS_motif       49170..49208
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0024"
                     /evalue="6.00E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="puwG"
                     /protein_end="2160"
                     /protein_start="2147"
                     /score="12.6"
                     /tool="antismash"
                     /translation="QYADFAQWQQQWL"
     CDS_motif       49461..49550
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0025"
                     /evalue="1.60E-17"
                     /label="C5_LCL_267-296"
                     /locus_tag="puwG"
                     /protein_end="2274"
                     /protein_start="2244"
                     /score="55.8"
                     /tool="antismash"
                     /translation="DILIGTPIANRNHREIESLIGFFVNTLVLR"
     CDS_motif       49599..49718
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0026"
                     /evalue="7.60E-25"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="puwG"
                     /protein_end="2330"
                     /protein_start="2290"
                     /score="79.4"
                     /tool="antismash"
                     /translation="RQVALDAYTHQDVPFEQVVEALQPARNLSHTPLFQVMFIL"
     aSDomain        50055..51233
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_AMP-binding.3"
                     /evalue="2.60E-115"
                     /label="puwG_AMP-binding.3"
                     /locus_tag="puwG"
                     /protein_end="2835"
                     /protein_start="2442"
                     /score="377.2"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="FEQQVQQTPDALAVVFDNTSLTYSQLNNRANQLAHYLQTLGVAPD
                     VLVGICVERSLDMVVGILGILKAGGAYVPLDPEYPQERLDYMLRDSQVSVLLTQSQCLK
                     SLPDVDNLRICLDTDWGIIETQSQENPVSEVAPNNLAYIIYTSGSTGKPKGVAIAHCSP
                     VALVAWALKVFTPQQLAGVLASTSLCFDLSIFEMFVPLSCGGMVIVAENALHLPELIAF
                     EQVTLINTVPSAIRELLNGPGLPQSLATVNLAGEPLPLSLVQQLYQRQTIHQVFNLYGP
                     SETTTYSTFALCNRGDSLAPTIGRAIANTQIYILDALMQPVPIGVRGELYIGGAGVARG
                     YLNRPELTAEKFIPNPFENSKFHRLYKTGDLARYLPDGNIEYLGRIDNQVKLR"
     CDS_motif       50241..50282
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0027"
                     /evalue="1.20E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="puwG"
                     /protein_end="2518"
                     /protein_start="2504"
                     /score="18.4"
                     /tool="antismash"
                     /translation="LGILKAGGAYVPLD"
     CDS_motif       50475..50534
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0028"
                     /evalue="1.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="puwG"
                     /protein_end="2602"
                     /protein_start="2582"
                     /score="30.3"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVAIAH"
     CDS_motif       50889..50912
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0029"
                     /evalue="1.30E+00"
                     /label="NRPS-A_a5"
                     /locus_tag="puwG"
                     /protein_end="2728"
                     /protein_start="2720"
                     /score="2.8"
                     /tool="antismash"
                     /translation="YGPSETTT"
     CDS_motif       51021..51110
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0030"
                     /evalue="1.10E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="puwG"
                     /protein_end="2794"
                     /protein_start="2764"
                     /score="59.3"
                     /tool="antismash"
                     /translation="PIGVRGELYIGGAGVARGYLNRPELTAEKF"
     CDS_motif       51198..51263
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0031"
                     /evalue="8.00E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwG"
                     /protein_end="2845"
                     /protein_start="2823"
                     /score="37.1"
                     /tool="antismash"
                     /translation="YLGRIDNQVKLRGFRIELGEIE"
     CDS_motif       51474..51500
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0032"
                     /evalue="2.40E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="puwG"
                     /protein_end="2924"
                     /protein_start="2915"
                     /score="4.7"
                     /tool="antismash"
                     /translation="GKVDRRALP"
     aSDomain        51558..51749
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_PCP.3"
                     /evalue="8.50E-25"
                     /label="puwG_PCP.3"
                     /locus_tag="puwG"
                     /protein_end="3007"
                     /protein_start="2943"
                     /score="78.7"
                     /tool="antismash"
                     /translation="EESLVTIWSEILGLKQVSIHDNFFDLGGDSIISIQIIARAAQVGV
                     QLTLKQIFQYQTIAELATV"
     CDS_motif       51621..51650
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0033"
                     /evalue="3.40E-01"
                     /label="PCP_mE"
                     /locus_tag="puwG"
                     /protein_end="2974"
                     /protein_start="2964"
                     /score="4.6"
                     /tool="antismash"
                     /translation="NFFDLGGDSI"
     aSDomain        51789..52706
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_Epimerization.1"
                     /evalue="8.00E-165"
                     /label="puwG_Epimerization.1"
                     /locus_tag="puwG"
                     /protein_end="3326"
                     /protein_start="3020"
                     /score="541.5"
                     /tool="antismash"
                     /translation="TGEVPLTPIQQWFLEQNSPHPDYFNQSVLLEVAPDLKPELLQQVV
                     QQLLEQHDALRLRFGRNDSQWQQINSDTSDIVPFQVFDLSALAHEAQQAAIETTAAQLQ
                     GSLNLSEGPLMRVALFKLGSDSLDQLLIIIHHLAVDGVSWRILLADLSTAYQQISRGEA
                     IQLPLKTTSFKDWAIRLQDYGRSPSLAAELDYWLASSRANVAPLPVDYPDGKESNTVGN
                     TAQVSVSLSESLTHALLQEVPQAYNTQINDVLLTALLQSFAPWTGANSVLVDLEGHGRE
                     ELFEEINLSRTVGWFTTIYPLLLEL"
     CDS_motif       51804..51833
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0034"
                     /evalue="2.10E-03"
                     /label="NRPS-E1"
                     /locus_tag="puwG"
                     /protein_end="3035"
                     /protein_start="3025"
                     /score="11.2"
                     /tool="antismash"
                     /translation="LTPIQQWFLE"
     CDS_motif       51861..51965
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0035"
                     /evalue="2.40E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="puwG"
                     /protein_end="3079"
                     /protein_start="3044"
                     /score="20.0"
                     /tool="antismash"
                     /translation="NQSVLLEVAPDLKPELLQQVVQQLLEQHDALRLRF"
     CDS_motif       52176..52241
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0036"
                     /evalue="2.60E-10"
                     /label="NRPS-E2"
                     /locus_tag="puwG"
                     /protein_end="3171"
                     /protein_start="3149"
                     /score="32.5"
                     /tool="antismash"
                     /translation="LLIIIHHLAVDGVSWRILLADL"
     CDS_motif       52650..52700
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0037"
                     /evalue="4.20E-08"
                     /label="NRPS-E5"
                     /locus_tag="puwG"
                     /protein_end="3324"
                     /protein_start="3307"
                     /score="25.3"
                     /tool="antismash"
                     /translation="NLSRTVGWFTTIYPLLL"
     aSDomain        52725..53189
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_TIGR01720.1"
                     /evalue="9.50E-49"
                     /label="puwG_TIGR01720.1"
                     /locus_tag="puwG"
                     /protein_end="3487"
                     /protein_start="3332"
                     /score="157.0"
                     /tool="antismash"
                     /translation="GAALKWVKEQLRTVPQRGIGYGVLRYLSGDSNIRQQLQALPQAEV
                     CFNYLGQFDHLQTEGIIQGFSQASSGATQSPLSHRRYLLEVNGLVAEGKLQLNWTYSKV
                     VHERRTIERLANEFITVLQGLIIHCQSPEAGGFTPSDFPIAELSQADLDEL"
     CDS_motif       52743..52805
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwG_0038"
                     /evalue="7.10E-11"
                     /label="NRPS-E6"
                     /locus_tag="puwG"
                     /protein_end="3359"
                     /protein_start="3338"
                     /score="34.2"
                     /tool="antismash"
                     /translation="VKEQLRTVPQRGIGYGVLRYL"
     aSDomain        53139..53201
                     /aSDomain="NRPS-COM_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwG_NRPS-COM_Cterm.1"
                     /evalue="1.50E-08"
                     /label="puwG_NRPS-COM_Cterm.1"
                     /locus_tag="puwG"
                     /protein_end="3491"
                     /protein_start="3470"
                     /score="26.2"
                     /tool="antismash"
                     /translation="PSDFPIAELSQADLDELLAEI"
     gene            53421..56729
                     /gene="puwH"
     CDS             53421..56729
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (5-36). E-value: 5.3e-20.
                     Score: 62.3. Matches aSDomain:
                     nrpspksdomains_puwH_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (14-315). E-value:
                     1.6e-118. Score: 387.0. Matches aSDomain:
                     nrpspksdomains_puwH_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (478-886). E-value:
                     1.3e-121. Score: 397.8. Matches aSDomain:
                     nrpspksdomains_puwH_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (995-1061). E-value: 3.4e-26. Score:
                     83.1. Matches aSDomain: nrpspksdomains_puwH_PCP.1"
                     /codon_start=1
                     /gene="puwH"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     396.6; E-value: 2.3e-120)"
                     /gene_kind="biosynthetic"
                     /note="non-ribosomal peptide synthetase"
                     /product="PuwH"
                     /protein_id="AIW82285.1"
                     /sec_met_domain="Condensation (E-value: 7.6e-77, bitscore:
                     247.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-128, bitscore:
                     418.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.7e-19, bitscore:
                     59.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVSDQTNKSKNVAAIYPLSPMQQGMLFHTLYAPESGVYFEQFSC
                     TLGGKLNVALFEQAWQKVVERHPVLRSLFVWENRKKPLQVVRHQVNLPWIQHDWRSLSP
                     SKQQGQLEEFLISDRTQGFQLDQAPLIRCALIRLSEETYQFIGSFHHLLLDGWSLPILF
                     QEVFGFYEAWNRGDNLSLATPRPFQDYIGWLQRQDLSIAEAFWRRTLQGFTAPTPLGVD
                     RMIKFDTHHQGSFHEQPFQLSATATAALQRFAQQHRLTVSTLVQGTWALLLSRYSGESD
                     VVFGATVSGRPPTLPGAESMVGLFINTLPVRVQIPEDAQTLPWLQQLQSQQVEQDQYSY
                     SFLVDIQGWSEIPRGMPLFESIVVFENYPVAAALQEPLDSLQVDNVRAYETTNYPLTLV
                     AASHQELYGRIVYDRDRFEADAIARMANHFQNLLIAISTQSEQPIKQLPLLDDAEKQQL
                     LQAWNAGKAEYPSEQCLHQWFEQQVEQTPNAIAVVFDNQSLTYAQLNTRANQLAHHLQS
                     LGVAPETLVGICVERSLDMVVGLLGILKAGGAYLPLDPDYPADRLEFILQDAQVSVLLT
                     QSQWLNSLTEVSAQTVCLDTDWEAISAFSQENPVNQATPNNLAYVIYTSGSTGKPKGVL
                     VNHANVTRLFTATQSWFNFNESDVWTLFHSYAFDFSVWELWGALLYGGRLVIVPFWISR
                     DPQAFYQLLCQEKVTVLNQTPSAFRQLIWVEEQAEVTVAKLYLRWVIFGGESLDPSSLM
                     PWFERHGDGTPQLVNMYGITETTVHVTFRPLTIEDAHSRGSVIGLPIPDLQLYILDESL
                     QPVPIGVRGQMFVGGAGVARGYLNRPELTADRFIQNPFSEQLGDKLYKTGDLARYRSDG
                     NIEYLGRIDYQVKIRGFRIELGEIEAALSQHPVVKEAVVIDREGKAGDKRLVAYIVSES
                     QSDTLMGELRCYLEEQLPDYMVPSAFVLLDVLPLTSNGKLDRRALPTPDMGNSHGVSFV
                     PPQTPTEDAIANIITSVLEIEKIGIHDDFFELGGHSLLATQVISRLRQTFSVELPVQVI
                     FTTPTIAELAELVIAKQLEQADNEALELILAEVNQLSDREVNLQLSDPTNHSSS"
     aSDomain        53436..53528
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwH_NRPS-COM_Nterm.1"
                     /evalue="5.30E-20"
                     /label="puwH_NRPS-COM_Nterm.1"
                     /locus_tag="puwH"
                     /protein_end="36"
                     /protein_start="5"
                     /score="62.3"
                     /tool="antismash"
                     /translation="QTNKSKNVAAIYPLSPMQQGMLFHTLYAPES"
     aSDomain        53463..54365
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwH_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.60E-118"
                     /label="puwH_Condensation_DCL.1"
                     /locus_tag="puwH"
                     /protein_end="315"
                     /protein_start="14"
                     /score="387.0"
                     /tool="antismash"
                     /translation="AIYPLSPMQQGMLFHTLYAPESGVYFEQFSCTLGGKLNVALFEQA
                     WQKVVERHPVLRSLFVWENRKKPLQVVRHQVNLPWIQHDWRSLSPSKQQGQLEEFLISD
                     RTQGFQLDQAPLIRCALIRLSEETYQFIGSFHHLLLDGWSLPILFQEVFGFYEAWNRGD
                     NLSLATPRPFQDYIGWLQRQDLSIAEAFWRRTLQGFTAPTPLGVDRMIKFDTHHQGSFH
                     EQPFQLSATATAALQRFAQQHRLTVSTLVQGTWALLLSRYSGESDVVFGATVSGRPPTL
                     PGAESMVGLFINTLPVRVQI"
     aSModule        53463..56603
                     /complete
                     /domains="nrpspksdomains_puwH_Condensation_DCL.1"
                     /domains="nrpspksdomains_puwH_AMP-binding.1"
                     /domains="nrpspksdomains_puwH_PCP.1"
                     /locus_tags="puwH"
                     /monomer_pairings="Thr -> Thr"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       53469..53507
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0001"
                     /evalue="8.00E-06"
                     /label="C1_dual_004-017"
                     /locus_tag="puwH"
                     /protein_end="29"
                     /protein_start="16"
                     /score="18.3"
                     /tool="antismash"
                     /translation="YPLSPMQQGMLFH"
     CDS_motif       53529..53648
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0002"
                     /evalue="8.20E-20"
                     /label="C2_DCL_024-062"
                     /locus_tag="puwH"
                     /protein_end="76"
                     /protein_start="36"
                     /score="63.1"
                     /tool="antismash"
                     /translation="GVYFEQFSCTLGGKLNVALFEQAWQKVVERHPVLRSLFVW"
     CDS_motif       53865..53930
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0003"
                     /evalue="3.90E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="puwH"
                     /protein_end="170"
                     /protein_start="148"
                     /score="35.3"
                     /tool="antismash"
                     /translation="FHHLLLDGWSLPILFQEVFGFY"
     CDS_motif       53976..54014
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0004"
                     /evalue="5.90E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="puwH"
                     /protein_end="198"
                     /protein_start="185"
                     /score="9.5"
                     /tool="antismash"
                     /translation="PFQDYIGWLQRQD"
     CDS_motif       54261..54356
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0005"
                     /evalue="8.20E-22"
                     /label="C5_DCL_263-294"
                     /locus_tag="puwH"
                     /protein_end="312"
                     /protein_start="280"
                     /score="69.6"
                     /tool="antismash"
                     /translation="DVVFGATVSGRPPTLPGAESMVGLFINTLPVR"
     CDS_motif       54405..54527
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0006"
                     /evalue="2.10E-19"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="puwH"
                     /protein_end="369"
                     /protein_start="328"
                     /score="62.0"
                     /tool="antismash"
                     /translation="QSQQVEQDQYSYSFLVDIQGWSEIPRGMPLFESIVVFENYP"
     aSDomain        54855..56078
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwH_AMP-binding.1"
                     /evalue="1.30E-121"
                     /label="puwH_AMP-binding.1"
                     /locus_tag="puwH"
                     /protein_end="886"
                     /protein_start="478"
                     /score="397.8"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FEQQVEQTPNAIAVVFDNQSLTYAQLNTRANQLAHHLQSLGVAPE
                     TLVGICVERSLDMVVGLLGILKAGGAYLPLDPDYPADRLEFILQDAQVSVLLTQSQWLN
                     SLTEVSAQTVCLDTDWEAISAFSQENPVNQATPNNLAYVIYTSGSTGKPKGVLVNHANV
                     TRLFTATQSWFNFNESDVWTLFHSYAFDFSVWELWGALLYGGRLVIVPFWISRDPQAFY
                     QLLCQEKVTVLNQTPSAFRQLIWVEEQAEVTVAKLYLRWVIFGGESLDPSSLMPWFERH
                     GDGTPQLVNMYGITETTVHVTFRPLTIEDAHSRGSVIGLPIPDLQLYILDESLQPVPIG
                     VRGQMFVGGAGVARGYLNRPELTADRFIQNPFSEQLGDKLYKTGDLARYRSDGNIEYLG
                     RIDYQVKIR"
     CDS_motif       55041..55082
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0007"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="puwH"
                     /protein_end="554"
                     /protein_start="540"
                     /score="18.5"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPLD"
     CDS_motif       55275..55334
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0008"
                     /evalue="1.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="puwH"
                     /protein_end="638"
                     /protein_start="618"
                     /score="33.4"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGKPKGVLVNH"
     CDS_motif       55866..55955
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0009"
                     /evalue="6.50E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="puwH"
                     /protein_end="845"
                     /protein_start="815"
                     /score="50.4"
                     /tool="antismash"
                     /translation="PIGVRGQMFVGGAGVARGYLNRPELTADRF"
     CDS_motif       56043..56108
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_puwH_0010"
                     /evalue="4.10E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="puwH"
                     /protein_end="896"
                     /protein_start="874"
                     /score="38.0"
                     /tool="antismash"
                     /translation="YLGRIDYQVKIRGFRIELGEIE"
     aSDomain        56406..56603
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_puwH_PCP.1"
                     /evalue="3.40E-26"
                     /label="puwH_PCP.1"
                     /locus_tag="puwH"
                     /protein_end="1061"
                     /protein_start="995"
                     /score="83.1"
                     /tool="antismash"
                     /translation="EDAIANIITSVLEIEKIGIHDDFFELGGHSLLATQVISRLRQTFS
                     VELPVQVIFTTPTIAELAELV"
ORIGIN
        1 ctatggtgat atttcactta gttttgccag tatttcaccc tttgttaaat gtttacctgc
       61 cccgcgtgca ttccgccatt taatcccttt atcttgacaa agctttcgca attcctcaat
      121 tttcattgaa gtgtaatctg gtacagattc taacatagat tctggcacta ttcctgatcc
      181 agtttctggc aatccttcta ttgttcgtgc ttcgttagaa accgaatact cagcagttgg
      241 tacaagtcgc caatttgaat ctcctgagaa ctccaaaacc cactgatgat aattgaacaa
      301 actctcccga tgaccaacac taataaaggt tgtgccattt tcttgcaact tttgatagag
      361 gttctcttca ttgctcaagt ctagggcgct ggtagcttca tctaaaataa cgtaacgggg
      421 acaagtgacc aacaatcgtg caaaagcaag tcgttgttgt tctcctagag acaatatatt
      481 ttcccaatat gcttctgtat caaaaccacc gactcttgag accaaatctg gaagattcac
      541 ttgttgcaga actagttcaa gttcctggtc tgtgatttga tgattgcggt tggggtaaag
      601 tagctggtcc cgcagggttc ctaaaaccaa ataaggacgc tgaggcaaaa acaaaatttc
      661 ttcgaggttg ggccgcacta tccgacctat accagcatcc cataaacctg caaccgctct
      721 taacagagaa cttttacccc gaccgctagg gccgactatc aacagacctg taccagattc
      781 aactgagagt gataagtctc gaataatcac cctctcataa tttggagttt gcaaagtgat
      841 atgctcaaag gcgatccggt ctccttccac tgtctcaatt tttctaccag actcctgttg
      901 tatctttgct gattccaaga tttccgagaa agtcgctaaa cgctgagtta aattaatgag
      961 cctaccggaa gagccaaatt ctgtcacgag tagtgctaat gcagctgcaa aataattaca
     1021 agctgtactg gcttgattaa cttctcctaa atcaatttga ttaaagaaat ataaaggtgc
     1081 gatcgctata aatggcaata tactaagaaa tgattgatag ctagtgttga atatttgttg
     1141 atctcgtcgc cattcggtca tttgctcaag agcctgaatc actttatcaa atctgcgctt
     1201 gactaagttt gattcctgag cttcacctcg aaaaaaagcg accgattcgg cattatcacg
     1261 aacatgagtt aaggaatagc tgtagtcggc ttcaccttca acttgagcca aattaatctt
     1321 tattagtctt tgactcagaa gcaccgcagc cagattagct actattccaa aaataactac
     1381 aattattgct accggtttat agataaacca gagaaccacc aaaaaggtga tcatatccaa
     1441 agttttttcc acaaaaacga acacaatttg ggtcgccatg cgagggattg gttcaatttc
     1501 ttgagcaatc cgctggtctg ggttttcaat gtcggatcga aaattaattt tgtaataagc
     1561 tcgattctgg aaatatttat ccaggatgta attattcaaa aactgatacc aatcgagggc
     1621 aatttttctt tttaaatatt gagaaagccc gataaatggt atcaaaacta tcagtacttt
     1681 tgcatataca aataataggc gaaagaaagc tgaagtatct tttagttcta ataagtctat
     1741 taagtcgcga gttacatagc tattgtaggc atttatgcca ttgatcacta acagcaataa
     1801 aagtattaga ccgagctgag accatgcgaa taaaacgtct aaaaatttcc tgccatcttg
     1861 agggtctgga taccagtaag gtttagcgat cgctaaaaat tgcttccaga actgtctata
     1921 agatgtatcc gtcgttaaga cctgattctg attggacttt tgggcgatcg gcaaattcat
     1981 aaaaagactc ggtatatggg aaactttttc ctaaaaactc agatgcccga ctgctctaag
     2041 aaatcgggta tcttgttgtt cacctatcag atgtagcatg acgaatggaa gttcccaact
     2101 tttcagctag aacttggaca ttcggcttaa ccatcatcgt caaatgagta cctgggacga
     2161 tatggatctc cactggttca gtagaaaact tgctccaacc caatgttggc tcctgtagcc
     2221 gctcaatata tccctcaatc gctgcttctt catcactcat ttcgctagca cgtaacaagg
     2281 taatcggact tttgtgaacc gactgcggga aataattact aaaggcttga gtgtgagttt
     2341 tataaacttg gataaaaccc cgaaattggg cttttccagc atcggcaggc agaatgttgg
     2401 tgattttcaa ctgttccaaa agatagtcca attgtgcctc cgcagttagg ggctgaagaa
     2461 tttcggggga aatattgaga gacttgccga atagccgttc aatggcagta ccaatttgca
     2521 ctaaccatgt cgtgtcatcc aactcaacct cgacagattg atcaggtgga atcggcgcag
     2581 ttgtatcgag aattgccagg agtgcaattt catgaccttg ctgttgtaac tgctgggcca
     2641 tctcaaaggc aactaagccg ccaaaagaat gcccccccag taggtaaggg ccctgaggct
     2701 gaacggtctg gatggctgtg atgtagtggg cggcgatatc ttcgatttgg gtcatcggtg
     2761 ccgattcccc gtcgagtccc tgaggttgca gactataaaa gggttgatta gcacctagac
     2821 aacgcgctaa ctcataaaag taaatcacat ttccacccgc accaggaaca caaaagaagg
     2881 gtgtatttgt cccgactggt tgaataggaa ccaaactcga ccagattgtg gtgtctgttg
     2941 actgacgcag cagatttgcc agttcttcaa tggtcggact ttggaagaga gtggctaggg
     3001 gtagttgttt gccaaattgt tgctgaattt gagccatcaa gcggatagcc aacagggaat
     3061 gcccaccaat ttcaaaaaag ttatcgcgga ttcccaccca gtcaacggct aaaacctctg
     3121 accaaatttg tgctagttgg agttctaggg ggtcgcgggg tgctatcgct gttggtggtt
     3181 gattgatgtt aaaaggtgct ggtagcgatc gccgatcaac tttgccgcta ggagttaaag
     3241 gcactgtctc caaggggata aacacagatg gaatcatata ctctggcaac cgctgttgca
     3301 agaacttcct taactgttcg ggggttgcgg gctgttctgg agacaacacc acgtatacta
     3361 ccaggcgttt ttcagcggcg gtttctccat aagcgatcgc gatcgcttgt tgaacttgag
     3421 gatgtagccc caaaactgct tcaatttcac ccagttcgat gcggaagccg cgcaccttca
     3481 cctgatcatc catccggcca agatactcaa tgttgccatc gggtaagtaa cgcgccccgt
     3541 cccccgtctt atatagacga ttgacttttg aattggtaaa gaagtcggga atgaatcgct
     3601 cctcggtcaa atctgggcgg ttaagataac ctctagcaac cccaacacca ccgatgtata
     3661 gctcacccct caccccaatc ggcacctgtt gcatctgccg atcaagaatg tagatttggg
     3721 tattatcaat agggcgaccg ataggtggca gggctggcaa ctcttctaac ccatcctcca
     3781 agctaaaggc agttaccaca tgggtttccg agggcccata ttgattatgc agactacaac
     3841 caggaagccg ccgtaagaaa tttttcaagg ctggggtaat ctgcaactgt tcaccggcgg
     3901 tcataatctc ccgtagaggt ggcagcgatt ccaccccagc agctgcctca gctaactgct
     3961 gcaaagccac aaatggcaga aaaactcgtt ctacactttg ttcactgagt aagcctaaaa
     4021 gagccgtggc atcccggcgt agtgcatctg gcactaacac caaagtaccg cctgcacacc
     4081 aagtcgtgaa catttcttgg aaagaaacat caaaactcac cggggcaaat tgcagggttt
     4141 tagcacttgc ggcaatgtga gtctggcgga tttgccaaag taggaggttt gttaaagcac
     4201 cctgagtcat cgctaccccc ttgggtgtgc ctgtagaccc agatgtataa attacataag
     4261 ctaagttatc cggctgtagt ctgctgtttg caggttctgg ctgaatttga gttagggacg
     4321 actgccattc agtatctaag caaactagcc gggactcatg ctctggcaat atatctatta
     4381 ggtgcgactg tgttagcagc actgccgctt gggaatcttt taacatatag cccaagcgat
     4441 cgcggggata agctgggtca aggggcagat atgcaccgcc agctttgata atccctagca
     4501 gtccgataac taagtccagg gaacgttcta ggcagatacc cactaccact tctggcccca
     4561 ctcccagggt ttgtaaatgg tgcgctagtt gattagcacg agcatccaat tccctgtatg
     4621 taagttgatc ttgtccaaac aatacagcca cagcatcggg ggtgcgttgt acctgggctg
     4681 taaacaactg cgggatagat tcggcagtat attctgtttg ggtactgttc cactccccga
     4741 ataactgctg ctcttgctca gtcagcattg gtaattggga aagacgttga tcaggatttg
     4801 tggcgatcgc tgtgagtaaa gtctcgaaat gtccaatcat ccggcaaatc gtctctgcct
     4861 cgaacaaatc gctgttatat tcccaccatc ctgttaatcc ctctttcgtt tcccaaatcg
     4921 ctaaggttaa atcaaactta gcggtaacat tctcaatttc taaaggcgta aaattcaacc
     4981 ccggtagttc taggttcccc atcggcgcat tttgcatagc aaacatcacc tggaacagag
     5041 gactgtggct aagtttgcgg tctggttgca aagcttcgac cacttgctca aagggtacat
     5101 cctgatgact gtatgcatct agtgccactt gccggacttg agttagtacc tcagagaatt
     5161 tgggattgtt gtcaactttg gttcgcagca ccaaggtatt gacaaaaaag ccgatgagag
     5221 gttcaatctc ttggcggttg cggttggcaa ttggcgtacc aatgagaatg tcatcttgac
     5281 cgctgtaacg atgtaataac gtcacaaagg ccgcttgcag ggtcataaat aaggttgtcc
     5341 ctgtttgttg gctgaggcgg ttgatctgct gactcaaatc ttgtttaatg gcaaaattac
     5401 agcgatcgcc acggaaggtc tggacagcag gacgtggttt gtcagttggt agttctaata
     5461 caggagacgc gtctgctaac tgttgcttcc agtagttgag cttggtgtct aacacatccc
     5521 cacttaacca ctgccgctgc cacaccgcaa agtcggcata ctggatgggt aattctggta
     5581 agggggaggg tttgttagcc gcaaaggctg gatagaggac ggacaactct tgaatcaaaa
     5641 tccccatcga ccaaccatca cagacgatat gatgcaagat gaacagcaat acatgggact
     5701 tttctcccaa ctgtatcagt gttgctcgca caaggggtgc ttgttcgagt tcaaagggtt
     5761 cttgcgcttc caaggcactt aactgttcta ctgccagggg atgttcctct gctggcaatt
     5821 tccgcaagtc cacaactggc aaagttagag tagcagtagg gttaattacc tggactgggg
     5881 aaccttccac caaatgaaag cttgtccgca agatttcgtg acggcggaca atttccacca
     5941 aagcctgttt cagggcatca acctgcaagt ccccagtaat ttccaccgca ttgggcatat
     6001 tataggtagc gctggctcct tctagttggg agaggaacca tagtcgctgt tgtgcccagg
     6061 acatcggcag atgaggcgtt attctaggtg ttggtgcgat cgcaggtgtg gtcagtcctg
     6121 aagcagtttg acgatggtta ttaataaact catccagttc cgtgactgtc ggcgcttcaa
     6181 acaaacatcg caggggcaat tctacctgga acgctgcttg caagcgggaa attacctggg
     6241 tagccaggag agaatgtccc cccagttcaa aaaagttgtc gtagatgccg actgactcca
     6301 gtaccaaaac ttcggcgata atctctgcaa tgatctcttc tgctggggtg cgtggtggca
     6361 caaaactcac tgtccgacta agttctagat ttggtgccgg caaggcaacc cgatcaacct
     6421 tgccattggt agtcaatggc aaaacaggca gcagcataaa agcattggga atcatgtacc
     6481 caggcagctt ttccttgaga aaattccgca gttgtggtat taatttccga gcgagttttc
     6541 cttgcagtaa gttattagca taagtactcc aaggtctgac tgacttggct tggtcaaaaa
     6601 cagggagaat actctgagaa gctgactctg aggcaccgcg tacaaagaca acatcatagt
     6661 caccattacc cgttaccgac caattaatgt gaactgtata aggtagttca tcctcccaag
     6721 cccataatgc ttctggatca acccctgttg ttggcgttac ttttggtaaa actgcattta
     6781 gctcacctac cgttgtcgat tcctgagtat tgaatagcaa atcaagcagc cgctcctctt
     6841 tctgaagtcg ggcgttgggg atttgtttga tgcctaaaat ttctggcttt gttgttgtca
     6901 gcagttcccg cagggaggtt aatgtgaggt catcctgctg ccagtcgagc cattggggga
     6961 cgactagagg agtaacttta tcgcctaaat ggagagtcac atcgtaacgg aactgggtta
     7021 actcgttgtg atagtcaccg cgtttaattt ggatttggac atgactgatt tgggggaatt
     7081 tgtgctgtag ggctgtaaaa aaggcggggt caattaccaa ttctggctct tgattaaggc
     7141 ttctctgcac ccgttggcgc aactcggcgg cggataggga agatggcgct tgatggaact
     7201 gaacagaagt atgaaatgct tccaataagg gcaggtggcg aacatccccg ataaaaatga
     7261 atccccctgg agtattagct gccactgccg ttgccacaac tctgatgagg taatcgatac
     7321 tgggaaaata ctgcactacg gagttgagga tcacagcgtc aaaggatgcg gtttcaaact
     7381 cctgaaactg atccgccgat ccctgagcta gctgcacctg tgaccagtct ccccccaact
     7441 tactcatttg ctgctcaaca tactgcaaag cgtgatggga aatgtcggtg ccatagtaat
     7501 gttggcattg ttgagcaatg cggaacagca gcagcccagt gccgcaacca atctctagga
     7561 cgcgatgggg ttgccagtaa agaattcgct ctacagtggc ttctacccat tgccgcatct
     7621 ctgttttggg gatcagtaga ccagtgcgac tgtcgttcca gccgataatg ttgaaggtcg
     7681 ggtctgaatc gtgtacagac tgactgtagc tatcgttaaa cacctgttgc cattgtgaga
     7741 gttgctcact ctggaattca gtgtcttcag ctggctcgct gtcttcgcca tcctgagagt
     7801 tgggaactac ataagcaact aaacgtttgt cgctgggtat gtcttctcgg ataatgacaa
     7861 cggtctcccg gacttctggg tattttgcga tcgcggcctc aatctctccc aattcaatgc
     7921 ggaagccccg caatttcacc tgattatcca tccgtcccag gtattcgatg ttgccatcta
     7981 gacggtaacg cgctaagtcg cctgttttat atagtcttgc ttctgagtca ttgctaaagg
     8041 gatttctgat gaaacgttct gctgtcaact ctggacggtt gaggtatccc cgcgctacac
     8101 cagccccgcc aatgtagagt tcacccctca ccccaatcgg caccggttgc cagaattgat
     8161 ccaggatata aagctgggta ttggctatcg ggcgaccaat caaaattccc tcggtcaggg
     8221 atgtttctgg cgtcacttca tagatgcagc agcccaccac cgtctctgtg gggccatatt
     8281 cattaatcag gcggatgttt ggtgcatatt gttgccaaaa ttgcaaggtt ttgccgagga
     8341 gagcttcacc accgatgact aatgcctgag tcgattctgg tagttcttct gggagaagta
     8401 gttgattgag taattctaaa tgggctggtg tgagtttaac taagctgaac cgacgacggg
     8461 aacgcaaaac gtcacagaga gcttcaattt cttgtttctc tggcagtagc acaacttgcc
     8521 ctcccaccat taaaggagag aaaatactgg taatggtggc atcaaaggcg aaggaagact
     8581 gcacaggtgc gccacagcca tcagcgacgg cataagcttg ggtacaccaa ctaaggtaat
     8641 tcaccacccc ttggtgccgg atcattgtcc ctttcggttc acccgtagag ccggaggtgt
     8701 aaattatgta ggctaaattc tggggttgta cctgagagaa tacattatct gtactctgat
     8761 gagcgatcgc ttgccaatca ctatctaaac acaaaatgcg atttacttct tctggcaaaa
     8821 tatccagcag gtgcgattgc gttaacaaca gcggcacttg ggaatcattt aacatatacc
     8881 gcaagcgatc gcggggataa gccggatcta gaggtacata agcaccacca gctttaagaa
     8941 tccccaataa gcccacaacc atctccagag accgttccac acaaatgccc actaggacat
     9001 cggcagctac acccaaggtt tgcaagtaat ttgctagttg attagcacga tgatttaact
     9061 cagagtatgt aaggcgctgg tcttcccaaa ccaccgccac agcctccggt gtgcgttgca
     9121 cttgttgctc aaaccattga tgcagacata aatgagtcgg ataatcagcc tgagtatcat
     9181 tccattccac tagcaaccgt tgctgttctg actccgagag cagcggtaaa tgggcaatcc
     9241 gctgggtggg attagccaca atctctgcca gtaacgtctg gaaatgtccc gccatctgaa
     9301 tgatagtgga ctcatcaaat aaatcgcggt tatattccca cgatccctcc agtccctctc
     9361 cgttctcaat caatgacaag gttaaatctc gctttgccgt ttccgtctgc atttccaaag
     9421 gagttaacgc caaatccagc agtttcagcg tgcctgttgg tgcattctgc aagacaaaca
     9481 tcacctggaa caggggatta tgatccaaat tccgttctgg ctgcaaagct tctacaactt
     9541 gctcaaaggg tacatcttgg tactcatagg attccagcga tacctgctgt acctgtttga
     9601 gtaaatccga gaacttagga ttgccttgga gcttagttcg cagtaccaaa gtattgacaa
     9661 aaaagccaat tagaggttca atttcctggc ggttacggtt agcaatcggc gtgccaatga
     9721 gaatgtcatc ttgaccgctg taacggtgca gtaaggtgac aaaagccgct tgcagagtca
     9781 taaacagagt cacccctgac ttttgactga ggctgttaag ttgctgagtc aggtgagtgt
     9841 tgagttgaaa agggtagagg ccaccgcgaa aagtctcaac tggagggcgc ggtctgtctg
     9901 tcggcaattc taataaaggg ggcgcacctg ctaacttttg ccgccagtag ttgagtttgg
     9961 tttctagcac ttccccactc aaccattgcc gttgccacac tgcaaagtca gcatactgca
    10021 cggttaaatc tggtaaaggt gagggttcac ccttggcaaa ggctggatac agaactgaca
    10081 actcttggat gaacactccc atcgaccaac catcaaaaac aatgtgatgc acagtcaaca
    10141 gcaggacatg ggaattttca ctcagccgca gcagtgtccc ccgcaataac ggaggctgat
    10201 agaggtcaaa gggtttgtct gcttctagca tcaccaaccg tttcacttca gtagattgct
    10261 cctgatttgg taatccttgc aagtcaacca ctggcaaagc taacgttacc ctgggagcaa
    10321 taacttgcac tggagtgtta ttgatttctt gaaagctagt ccggagggct tcatggcgat
    10381 gaacaatttc tgctaaggct tgctctagtg cagtcacatt caagtcgccg gtcatctgca
    10441 aagcgcttgg tgtattataa gtagcgcttg ggcccaccag ttgatcaaga aaccacagtc
    10501 tttgttgagc aaaagataaa ggaattgtct ggtctctggg tatgggagca ataggcagag
    10561 tttggatttt attctctgtt gcagaactta gcttctgcat ttgcagcttc ttcagaacca
    10621 gttcgcgctt ttctggcgag agatgatcaa gacgttttag caggtcactc atagttaaat
    10681 taaatcttaa actaataatg attttctata gcttcaaaag tatgaataac tataacttta
    10741 gtgaagtttt agaataccct gatgggtagc agaaaatatt cagatggtca ttgaaaaagg
    10801 gttatggcgg tgtaaccctt tttgcttgat tgatattctt gctgaattta tctcatcaat
    10861 tcattgcaca attcatctat atcctcctct ctctcgtcaa taatttgctt ggcgactcta
    10921 gtcagcatcc gaatattttc agctttcgca ttatccatcg gttccagtcg ttcatctaga
    10981 tatgcttgaa agcggtaata ctgtttttgg gaattatccg gagctcgcag caattgttct
    11041 aattcacaag ataccgattg actggtagcg tctaaaataa tgttgatcag cggtcttacc
    11101 caaccaataa gcccccaatt tctcgcctca ttgtaggggt ataccttagt gagagatcca
    11161 gtaccaagag aaaccaccaa gatgtcatca atagtccaag tttcttcccc tcttttggct
    11221 gccgctttgg cattattcag tgcttccatt agggctaaac tagtagggtt gttggcgaaa
    11281 actcccccat ctactaagtt gtaaaaactg cttgggcttt gggatgtttg aattcggtaa
    11341 ggagaaaaat aggttggagc agcactagtt gccattgctg cttgtttcat ggtaaagcct
    11401 ctacatatcc tccggtaact gtgagattgg gtgttttgtt ttttggggtt gcttgtaaag
    11461 aagactggcg tccttagctc gatatcataa ctggtgatga aaacttcttt tagggtttcc
    11521 tgtagggggg taaagtcaaa aaatctcttt aaaacatctt ctctgccttc agaagtgtat
    11581 tttggtttaa tgatgtcgtc gagatttccc agcaattcct caattatggg ttcgtaaaat
    11641 atttcagaac catactttgc aaacatactg accaaggctt gagcgctgta tgctggttct
    11701 ggaactccct cgctgtaggc aggagcattt gggttaggtt taggtttagt tagtcctagg
    11761 gctaaaattc ctcccgttga agttccagcg aagagatcga acatacttga aattggcttt
    11821 tcggttcgtc tttcaatctc tgcgagaatc atcgctggga taattccccg aataccgccg
    11881 ccgtcaattg acaaaattct gtatgggtaa gttcgttttt tctgttgtgt ctggggttgt
    11941 ttgactatgg ctgattcaga atgttcttga atgatcacta gaggctgtcc ttggatatct
    12001 ggttgggggt ttggttgggg ttgttcttga gtcactacag gagtttctgg ttgagggtct
    12061 ggttgggatt gttcttgagt cactacagga gtttctggtt gggggtctgg ttgggattgt
    12121 tcttgagtca ctacaggagt ttctggttga gggtctggtt ggggttgttc ttgaggggct
    12181 gttgggggtt gcggctgttt gacttctatt gggatctcag cctgtaacca agcggcgttc
    12241 ccggaaatag tgccgtggtt agcgttcttt gttttatctt gtactgtggt accagtgcct
    12301 tcattcaatg gccagtaacc cactaagccg ggttcgttac ccacaagacg ataagccatg
    12361 tcagctttaa tttcatcttg agaacgagct ttattccaaa tttgaagctc gctgatcatc
    12421 ccatgatggt aattctggag atcggtataa catcctaagc agacttttgc ggctggggaa
    12481 ataggctttg ttttgttaga ctcactatgc caaagttcac cattgacata gattttcatt
    12541 tctccagtcg tggcattttt agtaaaagcc caatgcaacc atttatttct atagtcacta
    12601 actggcattg ttttggtgat gcgatcatat ccagttaaat cgccacaatc aaaataaatt
    12661 atgctatttt gccaaggcaa atggatatta aaaagccgtg tgttattgtc gcttcttgcc
    12721 tcaattatag aactgtattt gggttgcaaa gtaccagcat tagaccaaaa actaacagta
    12781 atttcgctgc ctgatgggat actttttcct gggagttcta cataatcatc ttgaccatcc
    12841 aaactcagca caggttggag ttttgaaggt gttggcggtt gtttgacttc tattgggatc
    12901 tcagcctgta cccaagcagc gttcccggaa atattgccgt ggttggcgtt gtttgtttta
    12961 tcttgtactg tggtaccagt gccttcattc aatggccagt aanccactaa gccgggttcg
    13021 ttacctacaa gacgatggga tagattggac tggatttctg tctgggaaag cactttattc
    13081 cagacacggg cttccgcaat ttgacctttg aagaggaatg aagagttatg agacccaatt
    13141 tggagggtgc ggtctgaggg atcaaatggt tgcacatcac tggcttggct gactagacga
    13201 ccatctcgat acaagcacat aacttttgtc tggctatcat aggtcactgc cacatggaac
    13261 caagtattag ctgggctggt gctggaatct ttcacaaacc accattgacc gttgtgtcca
    13321 gatcccagta agccattggg cataaataaa gcatggttac gcccagaaag gatgttgtta
    13381 tgttgtgata gcggttcagc gagcttcacc caggcttcct ttgtatagga gttggtgaca
    13441 atcccctcag gacagttgat gtaatcattt tgcccatcaa aactcagcac aggttggagt
    13501 tttggaggtg ctggctgttg tttgacttct attggtaact cagcctgcac ccaagcggcg
    13561 tttccggaaa tagtgccgtg gttagcgttg tttgttttat cttttactgt tgtaccagca
    13621 ccttcattta atggccagta acccactaag ccaggttcgt tacccacaag acgacgagcc
    13681 atatcagcct taatttcatc ttgagagcga gctttattcc aaatttgtag ttcgctgatc
    13741 atcccatgat ggtaaagctg agagttgcta aaacatccca atgtcactct tgtggctgga
    13801 attaaaggca tagttttgcc cgttccgcta tgccacaatt cgccattgag atagattttc
    13861 atttctcccg ttgtcacatt tttagtaaaa gcccaatgtg accatttctg tttgtattca
    13921 ctggcttgag caagtttttc aatgcgatca aagccacttg cctggttgcc agaatcaaag
    13981 taaattttgc tttcgcccca aggcaaatgg atgttgagaa tccgttcgtt attggggcct
    14041 tgtgccccaa tgatagaact atgtttaggt gacaaacttc caccataaga ccaaaaacta
    14101 acggtgattt cgctgcctga tgggatactt tttcctggga gttctacaaa atcattttga
    14161 ccgtcaaatt ctaatactga ctgggttgct tgagccattg atgggatacc tagttgaagt
    14221 ttttccggcg taactcccgc taatgatgca gcgatcgcta gggtagtaga atagacacct
    14281 aatcgagcta aacaattttg tgggcttcca taagtttgcc aacacggtaa tacagattta
    14341 ctgaacccac gtgggttttt aggcagttac tctgattatc tagggcaatg ctggttaatg
    14401 aacctgtgtc atactgctga ctgggactcc acttaagcgt ttgctctttc tctgaaattg
    14461 ccataaatac tatttctttg aaactcccat aatttatact ttacaggtgg ctaaaggccg
    14521 ctgcacctgc ctaaatccgg attgctcaca agttctgcgg attaatttga ttaaatcgtt
    14581 cgccacgtag aaacagactg ctttgaaatt acattgcaag taatatcatg cccgtcgaat
    14641 tactcataat aaaataaccc caccccggtt ttatctgaca ccaaaacctt tcctcccagc
    14701 cagcgggtag gggattagga ggtagggtgc agtaaacatg ggaatcataa ctaaattaac
    14761 cggacatgat ataactcaat agtccttggt gaaaactgtg gtcaaaaatt cgattgaaaa
    14821 gataccccag actcttatga aagtagggac tggggactaa agactagcga aagaggaatt
    14881 tttgtagatg atgcctaatt tgcggttggg caataatgtc aattaaaatc caggcttggc
    14941 agttaaaaga ttttttgcct gtagctttcg acctggtgat ttagatggtc tctatcgctg
    15001 cctggatttt ctagcttgag gtgaagttat tgttcaaaac tgcctcaatc tatctcttta
    15061 acctgtggaa agtaggcgtc gctatctacg tcttctttct tcggcagggt gtctttcagc
    15121 ttttgtttca aatcgtcgga aataggcaaa ccgttaattt ctttgaggat acctgcgaga
    15181 gattcatttt tgctccgctc tgcatacaca taagacagaa gcttctcaat tccgtatcct
    15241 gctagcgctt cgctaacaag ggttgtcagc cctaacacgg ttaaaccacc aaacatacca
    15301 aaagggccac cgagaacagc tagggcgaat gggatagccg tagttactgg atatgcagtt
    15361 gtagccattg ttacaataag tattacgcct ggtagtccca gagacgcaat tactttaaca
    15421 atctcatcca tacgagttac ctgcttaatt gaatcgaaag tatacatagc ttattttacc
    15481 tttcttagat tatgtttcca agcggtaaag caattatcat ataggtcgct tgcctatgtc
    15541 aacttcactt ttattgataa acaggcatct agaggtatag tttgggatga actgacccaa
    15601 tttcagcatc aagttaacaa gtttatagtt gatgcatgat tacaggtctt ggtcaacgac
    15661 agaatattct ctggacagag aatatactgg tgtaggaaat ataattttta cataactgac
    15721 ccgataaaat agcaagattt atttatataa aatttataca gaatttatgg tatctaaata
    15781 ttatgggggc ttaacacagt ctcaaaagtt ctcaatagta aatattggtt tgcgtataga
    15841 aaatagagtt cagcaatttt ccgaaaaggt gctacttttg ttagtcctaa cttttggcga
    15901 ttgtggcaaa tgcttaggca acagtggtac tcaccgctac taccttaatt aatcaatttg
    15961 gcgaagtagt ggactcaaac gtctaaagta ggcgccatgc aatagctggt gactagggat
    16021 tataccaatg aaatatgtat aaactcgaat cggtatttta acatttagcg attaaagccc
    16081 aagctaagaa gaactagaat ggataatgaa cccattgcga ttatcggaat aggatgccgt
    16141 tttcctggta tcaaaactcc ggaagggttt tggcacttac tgcgtgatgg tgtagatgcc
    16201 atttccgaag taccaaagac aaggtgggat atagaatcct tctacgaccc agatccagcg
    16261 attccaggca aaatgagtac taagtggggt ggctttctag agcaagtcga gcaattcgat
    16321 ccccagtttt ttggaatttc ccctagagaa gcagcgggta tagatcccca gcagcggctt
    16381 ttgctagagg tcgcttggga agccttggaa gatgccggac agaagccgga acagttggtg
    16441 ggtaagcccg tgggtgtatt tacgggaatt tctaccttcg actactactg gcattggatg
    16501 aggaatccta gccagactga tgcctatttt gctacaggca ctgctaactg catggcggct
    16561 aaccgcattt cctacacatt taatttcact gggccaagcc tagcaattga tacagcctgc
    16621 tcttcttccc tggtggcagt tcacctcgct tgccagagtt tagggaatgg agagtctacc
    16681 ttagcattag cgggtggtgt gaatgtgatg acatcgccgt ggctatttgt gggttttagc
    16741 aagagcgggt ttatggctcc tgatggtcgg tgcaaaacct ttgatagtcg tgctaatggc
    16801 tatgttcgta gtgagggtgg cggttttgtg gttttaaagc tgctatctca agctttagcg
    16861 gatggcgatc gcatttatgc tgtaattcgt ggcagtgcta ttaaccaaga tgggcgcagt
    16921 aatggcttaa cagcacccaa ttctttggct caggaagcgg tgttaagaga tgcttaccgt
    16981 caagcgggag tttctcctgg tcgagtgcaa tatattgagg ctcatggaac gggaaccaaa
    17041 ttgggtgatc ccatagagat gaaagctttg ggtaaagtac tgagcgaaga ccgtcctcca
    17101 ggggaaatct gctcggtggg tgcggtgaaa accaatattg gacacacaga agctgctgct
    17161 ggcatcgctg ggttaattaa agtggctcta tcgttgaaaa atcagcaaat tccccccagt
    17221 ctgcattttc tagaggctaa tccctatatt ccctttgaca agctaccgct acgagttcag
    17281 cagacgctgg aaccttggcc aacaggagtt ggtaatgcct tagcgggagt tagttccttt
    17341 ggttttggtg ggactaatgc tcacgttgtc ctggaagcag caccacagga aattcaaaat
    17401 tcaaaattca aaattcaaaa agatgatcag agtaaccgtt ctgtgcatct tttgacctta
    17461 tcggcaaaaa atgaaacggc actgcaagca ttagcagaaa gttatcagga atatttgcgt
    17521 tcccatcctg atgaatcatt agctaatata tgcttcacta gcaatattgg gcgatcgcat
    17581 tttgagtacc gattagcgat cgccacagca tccacccaag aactgagtca acagctagaa
    17641 gcctttacca ctgggagcga gactagggga ctggtgcagg gaaaaataac cagccgcaag
    17701 ggttcaaaaa tcgcctttct cttcacaggt caaggttccc aatacattgg tatgggaagg
    17761 caactctacg aaacccaacc cagcttccgg tctaccatca accattgcga agaaagactc
    17821 agcccttatc tagaaaaacc tttattagaa attctttatc ctcaagaaga gtcaggggta
    17881 aacactcagc actttcttga tgaaacagcc tacacccaac cagccctctt tattctagaa
    17941 tatgcgatcg ccaaattatg gcaatcttgg ggaatagaac ccgctgtagt cctaggtcat
    18001 agcgtcggcg aatatgttgc tgcttgcatt gcgggagttt tcagcttaga agatggactg
    18061 aaactgatcg ccgcaagggg acggttaatg cagacattac caccggatgg ggcaatggtc
    18121 gccgtacttg cagacgaaaa gacagtgata gcagccattc aaccctacaa tgagcaattg
    18181 tccatagcgg cgattaatgg tgtcgaaagc ttggtgattt ctggacaatg gcaagccata
    18241 gaaagcgttt gtctggcttt gaacaatcaa ggagtgaaga ccaaacccct acaggtttcc
    18301 catgcctttc actccccctt aatgaaaccg atattaggag cttttgagga agtagcgaaa
    18361 accattacct actcatcccc caaaatcccc ttaatttcca acgtcactgg acaacccgcc
    18421 acaacagaca ttgccacccc tgaatattgg tgtcatcata tttcccagcc ggtgaaattt
    18481 gccgccagca tggcaacatt gcagcagcaa ggctatgaag tctttgtcga aattggcccc
    18541 aagccaacct tactaggtat gggtcgtcaa tgcctgccag aagcaaaagg tctttggtta
    18601 cccagtttac atccaaggca aaccgattgg cagcaaattc tagagagttt ggcagcctta
    18661 tacgtccggg gcattcctgt ggactgggta aagttcaata gtgactatga gtattctcgc
    18721 gtgtctctac cgacctatcc ttttcagaga cagcgttatt ggctggatac agcagaattg
    18781 ccgacacatc agccacaatt aagtcatcag aacctgcacc cgttactcgg tcaaagattg
    18841 caattagcgg gtttaaagga aattcgcttt gaatctcaca tcagccaaga ccaacccgca
    18901 tatctcaaag atcaccgcgt ttttggtgag gtaatttttc cagcagctgc ttatttagaa
    18961 atggtgttag ctgcgggagc gaagttgttt aaatctgaca gcttggtgct agaagacgtg
    19021 agtattctcc aagcattgat tttgtcagaa gaaattagga agctgcaatt aagcttaacg
    19081 ccccaaggca atgctgccta ctcgtttcaa atttttagtt gtagcgctac agaagaagag
    19141 ccatcatgga tgctccatgt ttcgggaaaa ttgctgcgag gagaaaaccc cagtacacct
    19201 gctcagacag acttagaaaa gcagtgtcag caagacatcg acaccatcac atactatcaa
    19261 caatgtagcg atcgcgggat agactacggt ttcagcttcc aagccatcga aaaactttgg
    19321 caatcggaag aacttaccac aggaaaagtg cagttaccat tggcattagt tgccgaagcc
    19381 ggagactaca caatacaccc agtattgcta gatgcctgct tccagctatt agggactgcc
    19441 ttaccgaatc agaatcagcc agatacctat ttgccaattg gaatcgagct attgcaaatt
    19501 gatcgccgtc ctggaaacca tgtatggagc caggtacaaa tcaatccccc ccaagatgca
    19561 aatcaacaaa ttctcagcgg tgatctgagt ctttacaccc ctgaaggaca gagaattgct
    19621 caaattaaag gtttccagtt gcaacgagca aatcatgggg atgtgttgaa tgaaacccca
    19681 gaaaattggc aaaactggct ctatcaagtc gaatggcggc aacaggtacg ctttattagt
    19741 caaaacctac caccaaatta cctgccatct ccccaggaaa tgagtctcaa acttagtccc
    19801 gacttggctg agttggtgaa gcgcttcaac ttagaaggct ctggggacgt tttctcccat
    19861 ctggaaaaat taagcctcac ctacatcatt cgcgcttttg ccgatatgaa gtggaaattc
    19921 cagctagggc aacgcttctc aaccgcagat attagcactc aattgggagt aatcaaccaa
    19981 catcagcggc tactggggcg gcttctagaa atcctggctg aggggggata cctgagacaa
    20041 attaactccc agtgggaggt aattaaagtc ccccaggagt ccaacccaga ggcgcaatta
    20101 aagatcctgt ttcagcaata cccaacagcc gcagccgagt taactttatt ggggcgttgt
    20161 ggttgcaaac tggcagatgt actgcgggga aattctgatc ccctccagtt gctctttccc
    20221 gaaggagatt taaccaccgc cactcaggta tatcaagatt ctcctggggc aaagttgctg
    20281 aatacccaag tgcaacaggc aatctcatct gctgtggcac ggttgccgaa agaccggggt
    20341 gtgcgcgtgc tggaaattgg tgcgggtact ggaggcacca ccacatatat tttgccagtg
    20401 ctaccggccc agcagacaga gtatgtcttt accgatttat ctccccggtt taccacccag
    20461 gctgaagaaa agtttcggga atatcccttt gtaaaatatc aggttttaga tattgagcaa
    20521 gacctgaaat cccaaggatt tgaatttcat caatatgatc tgattgtcgc tgccaatgtt
    20581 ctccacgcca cccaagattt acgacaaacc ctgcaaaaca tccgccaact tttagcccca
    20641 aatgggttgc tcgtgctgtt ggagggcact gctcgccagc gttggttaga tttgacattt
    20701 gggttaactg agggctggtg gtggtttaca gatacagatt tgcgtcccaa ctatccctta
    20761 ctgacaaata accagtggca gaatttgttg ctgcaagtgg gatatcaagc agccgttacc
    20821 ttgcctttgg tgcaggaaag tcaatctgtg attgtggctc aagctggctc atctcagtta
    20881 accgtcgcag cggctcaacc aaagcattgg ttactgttgt gtgataatca cggactgggt
    20941 gagcaattgg cggcacaact gcggcaaaag ggtgaaattt gtaccctcgt tttcccagga
    21001 gagcttgctg aaaaacttga tgagcaaacc tttgctatca atccccagca accagaagat
    21061 tttcagcaat tgctaagaga tataagccat cagcctgcaa tacacggtgt tgttcattgc
    21121 tggagcttgg atacagttgg ggcagatgtt ttaaagagtt ctgatttaca aggggcatct
    21181 caacaaagtt gtggcagtac cctgcatcta gtacaagggt tggtgaaagc cagcttgtca
    21241 cctcgcttat ggttagttac taggggggca cagtcggtag gagacgctgt ttctggggtg
    21301 gctcaatctg ctatctgggg gttggggaaa gtaattgctc tagaacatcc agaactgaaa
    21361 tgtgtgcgag tggatttaga tcctgatgtt cttggagatg cagcaccagc cttgtttgcg
    21421 gaagtttggg cagatgatgc agaagatcaa gtcgctttcc gtaacgggct gcgctatgtt
    21481 gctaggttaa ttcgttctgc ccagtcggaa attcctctga atcaaccctt taccttgaca
    21541 atttcccagc ggggtacttt ggaaaatctc acattccaac ctgcggtacg ccgtttacct
    21601 gatgcgggtg aagtagaaat tcgggtgcgg gcaacggggt taaatttccg agatttgctg
    21661 aatgctttag atttataccc aggtgatccg gggcctctgg gtggggaatg tgcaggtgag
    21721 attgtggcta ttggcgcggg agttgagggg tttgctgttg gtgatgctgt aattgcgatc
    21781 gcaccagcta cttttagcca atacgcaacg gtgaatgctg cattggtagc acccaaacca
    21841 gccaacctca gctttgaaga agctaccacc atccccatta ccttcctcac ggcttactac
    21901 gccctccacc acctcgccaa aatcgctcca ggggaacgtg tattaattca cgctgcggcg
    21961 ggcggagtgg gtcaagcagc catccaatta gctcaacagg tgggggcaga agtttttgcc
    22021 accgctagcc ctggtaaatg ggaatttctc aaatccttgg gagtgcaaca tatcatgaac
    22081 tcccggactg tagaatttgc cgaacaaata ggggaaatta ccgggggtga gggcgtcaat
    22141 attgtgctta actccctgac ttctgatgaa ttcattgcca aaagtctatc ggtgctttca
    22201 tcccaagggc ggtttgtgga aattgccaaa cggggtgttt tggatacaga agagatgttg
    22261 gcggtgcgat cggatatcgc ttactttcta gtcgatttgg tgctagtttg tcagcagcaa
    22321 ccagccttaa tccaatcgat gctgcgccat ttgatgccgc agtttgccgc aggtaagctc
    22381 cagccgctac cacaaaccgt cttccccatc caaaacgtgg ttgatgcttt ccgctatatg
    22441 caacaagcca agcatatcgg gaagattgtt gtcacacagc cagcagaact gaccttgcgg
    22501 ggcgatcgca cttatctaat taccggcggt atgggtggct taggcttatt gattgcccgt
    22561 tggatggtgg agaatggcgc caaacattta gtgttgcttg gtcgtagtat ccccagcaaa
    22621 tctgctatag aaaccttgga agtactgcaa aataagggtg ctgaggtgat ggtagttcaa
    22681 gcagatgtga cagatgtggc acaaatgacc caagtgattg cagaaattga gcgatcgcac
    22741 ttccccctca gtggcgttat tcatgccgtg ggggtattgg atgatggagt gctgcaacaa
    22801 caaacatggg aacgctttgc acgggtaatg gctcccaagg tagaaggcgc ttggcatctg
    22861 catcaattaa cccaaaatct acccctagat ttcttcgtgt tgttttcctc agtggcttct
    22921 ctatttggct cacccggtca agccaatcac gccgcagcca atgggttttt ggatgcttta
    22981 gccgcttacc gtcaacagca gggactcccc ggtttgagta tcaattgggg agtcgtcgcg
    23041 gacatcggag ccgccgcaaa acgtcaagct gacggatggg tgaaaaccaa aggcatggga
    23101 accatttctc ccccgcaagt tttggagata ttagcacagc aattgcaaac accagccgct
    23161 gctcaagttg gggtggttcc cgttgactgg tcaaaattta tcgcccaatc taccccttgg
    23221 tcattcttca gtgatttcca acaaactgac gactcccaag aacaaccaag ccaaaattcg
    23281 gaattacgcc aacagctaga agttataccc aaaaatgaac aacgtgctta cctaacaaat
    23341 tacctctgca cccaagttgc caaagtgctg ggacttaatt catcaacctc catcgatatt
    23401 cagcaaggat tttttgattt aggaatggat tccctcacct ctgtggagtt gagaaaccgc
    23461 ttgcaaacga gtttaggatg cagtttacct tccaccctca ctttcaaata tccgaccgta
    23521 gcggcattgg tggattattt agctgtagaa gtactggctt tagccaccac agtagaaata
    23581 accccacaag aaaccaaagt aaatcaagag ttagaagccg tcaaacaact ctcgaaagat
    23641 gaacttgaag attcaattgc tcaagaaatt gccgaattag aagcgttact gagggggaac
    23701 taggaaatgc aaaattcaac attcaacatt caacattcaa cattcaacat cgttcgactg
    23761 agcgctcacg acgaagttca aaatccccat ttctcaactt ttgtagagtt gctgcgttac
    23821 agagccatat ctcaacctga caaaattgct tttacctttc tccaagatgg agaaacagaa
    23881 acaggtagcc taacttatca agctttagat cagcaggcaa aagcgatcgc agttcagtta
    23941 gaatctgtag cagcaaaagg cgatcgcgcc atcatgcttt acccatctgg gttagaattc
    24001 attaccgcct tttttggttg tttgtatgct ggtgtcgtcg ctattcccgc ttatccaccc
    24061 cgacgcaatc agaatctatt cagactccaa tctatagtga cagatgctca agcaacggta
    24121 gcattaacga ctacggcttt atcaagtgac ctcaaacagt ggtttaatca aaattcagaa
    24181 ttagccacag tgaaatggtt ggtgacagat gaaatcgata gtaatttggc atcagtttgg
    24241 cagcaaccag aactgaacag caacacccta gcgtttctgc aatacacctc cggttccaca
    24301 ggtacaccca agggggtaat ggtcagtcac agcaatttgc tctacaacga ggaaatgatc
    24361 aaacttggct tccagaatac tgagcaaagc atcattgctg gctggttgcc cttttttcat
    24421 gacatgggat tgatggcaaa tttattacaa gccgtatatt taggggtacc atgctttttc
    24481 atgccgccgg tggcatttct ccaaagacca taccgctggt tacaagttat ttctcgttac
    24541 aaagcgacta gcagcggtgc cccgaatttt gcctatgacc tatgtgtgaa taaaattact
    24601 cccgaacaaa tatctagtct tgatttgagc agttgggatc tagccttcaa tggtgctgaa
    24661 cccgttaacg cagcaacctt agagcgattt accgccaagt ttgcagctta tgggtttcgt
    24721 cgcgaagcct tttaccctgg ctatgggatg gctgaggcca ccttattaat ttctggaggg
    24781 ttgagaaaag ccgcacctgt agtgttatct gttgctgggt caaatcttga gcaaaacaga
    24841 gtgttagtaa ctaccgatga acaggagggg agcaaaaaaa tagttggttg tggtcaaact
    24901 tggttagacc agaaaattgc gatcgccgat cccgacacct tgacccattg tagcgctgaa
    24961 caagtaggtg aaatttgggt atctggtgcc aatgtagctg gtggctactg gaaccgacca
    25021 gaagagacag agcaaacctt ccactcttac ttcgctgata ccggagaggg gccgtttctc
    25081 cgtacaggag acttgggatt tttgcgcgat ggtgagttgt ttattactgg acgaattaaa
    25141 gatgtaatca tcatccgggg acgaaataat tatccccagg acattgaagt cactgtcgaa
    25201 cagagccacc cagcactgcg tcccagtaac ggtgcagctt ttactgtaac tgtcaatgaa
    25261 caagaaaaat tgatcgtcgt tcaggaagtc gagcgaactt ggctgcggaa actggatggg
    25321 gagacggtag ttaaaacgat tcgtcaagca gtagcacagc agcacgaact acaagtttat
    25381 gcagtagttc tgattaaaac aggtagtatt cccaaaacat ccagcggcaa aattcagcgt
    25441 cgagcttgtc gagccaagtt tttagcagga acactggaag ggttgacctc agataagtag
    25501 aacggcataa ttaatcaaaa ctatatcacc atcagtataa ctggagaaaa caaagcaata
    25561 gtaaagggtt tagttaattt agggattgtt gcatattttt gtttatttgc gctgttatac
    25621 ttaaatataa ctctggaatc gatgaggtaa tgtattgcat acacctgttg ccttcttaga
    25681 ccaaattaaa ttaatcagtt ttaaaaaaaa cttggttgag aaattagttt ttacattaga
    25741 aaaaaggaaa tttgacaagc aatgaaaagt gagcaaatca cccaggaatt aatcgaactc
    25801 aggggtaaaa aacaaattcc atctctcacg gaaattcaag attggttaat tgtgtacacg
    25861 gcagaaatgc tggaaagttc gcctgatgaa attgatgtaa ctatgctttt tgatcaatat
    25921 ggtttagatt cttccatgac tgtaggaatg attggtgact tagaagtttg gcttgggtgt
    25981 gagttagatc caactttgat ttatgattac tcaactattg aactattatc tcaacattta
    26041 ggctcgattt tagctacaaa aaactagaga actataaaat aatcacaata gttcatattg
    26101 ttctatatca aatatctgaa agcttgactt atagcatttc tcagttaagt gaggtacaga
    26161 taatattttg aaacgcaaag ggacgcaaag taaagcgcag aggtacgcag agatttgtac
    26221 ctcagcagat taggaagctc tatacataca gtcaattgtc tatttgtaca ttgcttaagt
    26281 cctcaaaata tccaacaaat tgccgagcta gtagggttac tgagagaaaa gttaaatgaa
    26341 taatatctcc gaagcagtag agcagctatc ttcatcccaa cggatgctgt tggcgctcaa
    26401 ggaagcacga gctaaattag aagcatttga tcgtgctaaa accgaaccga tcgcaattat
    26461 tggtatgggt tgtcggtttc ctggtaacgc caacaaccca gaggcattct ggcagttatt
    26521 gcgcgatggc gtagatgcca ttaccgaagt gcctaaaagc cgttgggaca ttgatgaatt
    26581 ctatgatccc gatcctcatc agccggggaa gatttacacc cgctatggcg gctttttgtc
    26641 agatgtagac caattcgatc cccagttttt tggcattgct ccacgggaag ctgtgagcat
    26701 ggctccccag cagcgcttgc tattagaagt gggttgggaa gctttggaga acgctggcat
    26761 caatcccaaa aagctggtgg gtagtcccac tggggtcttt ctaggcgtcg ggccaaatga
    26821 ctatgccaaa ctgcgaatga acgccagtga acctgcgggg atcactgccc atgatggcac
    26881 tggcaatggt ttgtgctttg cctctggtcg cttgtcttat gtgttggggt tgcaagggcc
    26941 gaacttagcc acagatacct cttgctcgtc atctttagtc gcggtgcatc tggcttgtca
    27001 gagtctgcga gcgggggaat ctaatctggc acttgcaggt ggggtcaatt tgaacctctt
    27061 cccggaaacc acattgtttc tctccagaac ccatgcattg gctcctgatg gacgctgcaa
    27121 gacctttgat gctgctgctg atggctttag tcgcagtgag ggatgtgggg taattgtcct
    27181 caagcgcctc tcagatgccc ttgcagatgg cgatcgcatt tgggcaatga ttcgcggttc
    27241 agcgattaac cacgatgggc caagtagcgg tctaacggtg ccaaatcaac tcgctcaaga
    27301 gcaactgatt cgccaagcat tgcaaaatgc caaagtgacg ccagagcaag tgagttacat
    27361 agaggcacat ggtaccggta cttccttggg tgaccccatc gaagtcggcg cactagcagc
    27421 aatcttttgc caaaaccgtt ctttagaaga accgctgatg attggttcag taaaaaccaa
    27481 cctcggacac ctagaggcgg cagcgggaat tgttggtttg atgaaagcag ccctggcact
    27541 gcatcacggc gaaatccccc cccatttaca ctttcagcag cctaacccgc atattacctg
    27601 ggataacctg cctgtggtcg tacccactac ccgcacccct tggaatcggg gagacaaacc
    27661 actgattgct ggggtgagtt cctttggcat gagcggcact aatgctcaca ttgtcttaga
    27721 agcggcacca caggaaatta aaaattcaaa attaaaagtt aaaaaagatg tgaatctttt
    27781 gactttatcg gcaaaaaatc agtcggcatt ggcagaacta gcgcagagtt atcaggaata
    27841 tttacaagcc catccagaga tatccttggc ggatatttgt tttacggcga atacggggcg
    27901 atcgcatttt gatcaccgtc tcgctgttgt ggctgcgtct cctgtggagt tacaagaaca
    27961 tctccagaac tttgctgccg gcaaagaagc ctttggactg ctacataatc aagtcactca
    28021 gcgtcagcaa cccaaaattg cctttctctt caccggtcaa gggtcgcaat acctcgacat
    28081 gggaagacaa ctctacgaca cccaaccgat tttccgccaa acccttgatc gctgtgatga
    28141 aattttacgc ccttatttag aaaaaccttt attagaagtt ctttatcctc aatcccccct
    28201 caattcccaa tccctcgatg aaaccgccta cacccaaccg gcgctgtttg ccttggaata
    28261 tgccctctat gaattatggc gctcttgggg cattaaaccg aatgctgtag ttggtcatag
    28321 cctaggcgaa tatgttgctg cttgtgtggc tggtgttttc agtttagaag atgggctaaa
    28381 gctgattgct caacgggcgc agttaatgca gtctctgaag gcaaaaggca gcatggttgc
    28441 ggtgtttgcg cctgaaagca aagtgctgtc agcaattcaa ccctacatca aggaagtggc
    28501 gatcgccgcg attaacggga ctgagaacat tgtgatttct ggtcaacagc aggctgtaga
    28561 agcagttgta gcagttctgg aagcagaaaa catcaaaacg cgatcgctca cggtttctca
    28621 tgccttccac tctcccctgg tggagccgat gctggctgaa tttgcggtca tactccagca
    28681 aatttccttt caaccacctc agattcccgt tatctccaat ttaactggaa aggtgctagc
    28741 tgctggcgaa attcccgatg caaactactg gaaacgccac acaagagaac ccgtcagatt
    28801 tatggacggg gtgaatgcgc tttttgagtt gggatgcggc atatttttag aacttggccc
    28861 caaaccaatt ttgactaatt tgggtaaaca gtgccaacca gaaaacaatg cggtttggct
    28921 ctcttgttta gcagcaggca gagatgattg gcatctgcta ctcaataccc tatcggcctt
    28981 atacgtccag ggtgtagcga ttaactggtt gggatttgag caagattatc cacacagcct
    29041 tgtctcactc cccacctacc cctttcagcg gcaaagttat tggattgaaa acaacaacgc
    29101 ccccataaac tcccaatcaa gtcaaacctc ccaaccccta attagtatgc ccatccagac
    29161 ccaacgacga gcagaaattc aggaaaaatt gcgatcgcta attgcccaag tgctgcaagt
    29221 tcctcttaat ggtgttgatg ttcatacttc attcttggag atgggagccg actctatttt
    29281 cttgatggaa ggggtgcgaa ccattgaaaa cacctttggc atcaaaattg ccatgcgcca
    29341 gttttttgag gagttatcaa cccttgaggc tttagcaacc tacattgatt tacaactacc
    29401 cccagcagtg gctgaagtta atcccctccc cagtgagccg agtcaacctg caacacctat
    29461 tcaaccgacg acaaatgttg tagtaacttc ccccgtcaac agcatcagca atggggctgt
    29521 atcggtggca ggaggggcaa tggaacgcct gatggcgcaa caactccaag tcatgtctga
    29581 gcaattggca gttttgcgcg gtacaccttt gtcagtccag ccgatttccc catcatccaa
    29641 tggaaatgga actaacggac atggaactaa cggacatggg gcaaacagca atttcaaaaa
    29701 tgtccccaaa ccttcctcaa atccccttgc accccaaccc atttcctcag ccggtggact
    29761 taccccacag caacagcgtc acttggaagc tttgattaat cgttatactc aacgaacaca
    29821 aaaatctaag caacgcgccc aagcatcccg tccccattta gctgataacc gagccgtagc
    29881 aggctttcgg atggggatta aagagatgct gtatcccata gttggcacaa gatatcaggg
    29941 agcgaacttt tgggatttag atggtaatga gtatgtcgat ttggccatgg gttttggtac
    30001 ccatttgttt ggccatggtg ctacttttct caaccaagcc atccatgagc aaattaaaca
    30061 aggtattgct gtcggccccc aaccagcgtt agccctagag gtttgcgaac tcctgtgcga
    30121 actgacaggt tcagagcggg ctaccttctg tcagtcggga tctgaagctg tgatggtggc
    30181 attacggttg gctcggacag caactaagcg cgatcgcatt gccttattta ctggatctta
    30241 ccacggtcat tttgatgggg ttttagccca agctcaagaa atgagcgccc aacccctcgc
    30301 ccctggcatt gcgcctaaca ccgtcaaaga tgtgctggta ttggattacg gcgacccacg
    30361 ggcattagaa atcctcaaag ccgagatgca caccttggca gcggttttgg tagaaccagt
    30421 acaaagtcgc cgtcctgact tgcaaccaag agaatttttg catgaactgc gtcaaattac
    30481 ccaagctggg ggaactgccc taatttttga cgaaatcatg acagggtttc gcatccatca
    30541 agggggggca caggctcatt ttggtgtgca ggcagatttg gcaacctaca gtaaaatatt
    30601 tggtggtggt ttgcccttag cggcgatcgc aggcaatgcc aaattcatga acggaattga
    30661 cgggggattc tggaactaca gcgatcaatc ttacccccaa gcagaccgga cattctttgc
    30721 cggcaccttt aacaagcatc cgttatcttt atctacttgt cgcgcagccc tcagacacct
    30781 gaaagaacag ggtacacagc tgcaaacaga attgaatcag cggactgagt atttagttga
    30841 gcaactcaat caattcttta ccgagcaaga agtagaattg cgggttgtca atttcggttc
    30901 tctcttccgt tttgtcttca aaagcaactt ggatgtgttc ttttatcacc tcctggaaaa
    30961 gggagtttac atttgggaag gacgcacttg ttttctttca actgcccata ccgaagcgga
    31021 tattaattgg atcattcggg ctgtaaaaga aagcatccaa gagatgcggg tagggggatt
    31081 ttttcctgaa ttagcgcaaa atgggcgggt tcaggaaaaa actcccgtta gtcaaaacgg
    31141 gttttgggaa cggcgtagcc acaaatacgc tgctgtgtca agtaagccga cagcactgag
    31201 ggcaaaaact agcgtagatc ccaacaaaac agtgcaattc agcttgtatt atttcggcaa
    31261 ctatgaatca gaattcagcc atgataagta caacctgtta tttgccggcg ctaagtatgc
    31321 tgatcaacat ggatttaccg ccgtttggat tcctgaacgc cattttcacg cctttggcgg
    31381 cttttctccc aatccttcag taattgcagc tgcgatcgcc agagaaacaa aacagattca
    31441 aattcgttca ggcagtgtag tgctacctct ccatcacccg attcgcgtgg tagaagaatg
    31501 gtcagtggta gacaatttat ctcaaggtcg agtggggatt tcctttgctt ctggttggaa
    31561 tcccaatgac tttgccctag ccccccaatc cttcggcaac catcgagaac tgatgttcca
    31621 aggtatcgaa accgtccgca agctgtggcg gggtgaattt attcaagttc aaaacggagt
    31681 cggtaaaagc atcagtgtcc aggcgtttcc tagaccgatg caagctgaat tgcccgattg
    31741 gattaccgtg gtgaataatc ccgaaaccta tatcaaagcc ggagaaatgg gttctggggt
    31801 tttaacgaat ctgatgggac aaagcatcga agatttggct gaaaacattg ccctctatcg
    31861 ggaatcccta gaaaagcacg gttataatcc agcatcaggg aaagtgacgg ttttactcca
    31921 tacctttgtg ggtcaagatt tggaacaaac ccgcgagata gcaaggcaac cactgtgcga
    31981 ttatcttaaa tcttccgttg ctttattcca aaatttagtt aaaagtcaag ggttgcaagt
    32041 tgatttcgat caaatgacgg cagatgatca agattatatt ttatcggctg cctacaatcg
    32101 ctatgtgcaa tccagcgccc tgattggtac accagcatct tgcgctgaag tgattgctaa
    32161 gttgcaagca attggagttg atgaagttgc ctgtttgatt gattttgggg taaatactcc
    32221 ggctgttgtc gagagtctgc ctgatttaaa tgccctcaga gaactttgtc aaccaaaaac
    32281 aggggaacag gaaaaagaac cttccccctt gcctattgcc tcattgcccc ttgcctcatt
    32341 gcctattgcc tcattgcctc tttccccgat tcccttaacc gaagcgcaaa agcagttatg
    32401 ggtgctagca caaatgggcg atgatggttc aattgcctac aacgaatcgg tcagtcaaca
    32461 attacgcggt tcgttgaatt tagtagccat gaatcaggca attcagcaac tggtagaaag
    32521 gcatgaagcg ctgcgaacca caatcagccc ccagggggat gtgcaaaaaa ttctccctga
    32581 actgaaatta gatttagcgg tgattgattt ttcagagcta acgaatagcg atgggctacg
    32641 ccccgctgga agcgatcgca catctcaagt tacagcctgg ttaacccaag aaagtcaatc
    32701 accatttgat ctatcttccg gccccctctt ccgtgttcat ctccttaagc tagaagcaaa
    32761 actacatttg ctagtgctga gtgcccatca cattattgtt gatggctggt cacttggggt
    32821 aattttgcaa gaattaagcg ctttgtattc agccgcttgt cagggtgtag attgccaact
    32881 caaacccccc atgcaattta gacaatacat tgagtggcaa actcagcaaa gtcagacagc
    32941 agagatggca gaacatgaag cttactggtt gcaacaattt gctaactcga ttcccgtttt
    33001 agatttgccc tgcgatcgca cacgctcccc tattaaaacc tatcagggca gtaagcaaag
    33061 catcatccta gatgccagtc tttcccgtgc tatcaagcga gttagtactg aacaaggtgc
    33121 caccttgttt atgactttgc tgtcggtcta taccgcctta ctgcatcgcc taacgggaca
    33181 ggatgagatt gtagttggca ttcccacatc tgggagatcc ctagagggaa gcgaagggtt
    33241 agttggttat tgtgcccatg tcttgccaat tcgtagttcc gttattggtt ctagctcctt
    33301 ctcagagtat cttctagcca tcagagatgt gttgttagac gcatacaaac atcaagatta
    33361 tccattcgct aaattgattc aagccttgaa tctcaccaga gatgctagca ggtctccact
    33421 ggtcgctacc acatttaact tagatcgcgc tgccgcagta ccaaaattat ttgaactaga
    33481 aacaagttgg ttcgcgcaac ccatcagctt cacagattac gacattcatt ggaatattac
    33541 ccagattaat gatgaactgg tggttgattg caattacaac actgatttgt ttgaggctga
    33601 aaccattcag cgctggctag gacatttcca aactttattg ttagcagttg tagccaatcc
    33661 cacccagtca atggggcaac taccgttatt aactgagaca gaacgacagc agttattagt
    33721 gacgtggaac gccacccaaa cagattatcc cgccgacaaa tgtattcatc aacaatttga
    33781 ggtgcaggta caaaagacac ctgatgcggt agcactgcta tgggaagatc aacaactcac
    33841 ctacgcacag ttaaatgtgc gtgcaaatca attagcgcac tacctgagaa aacaaggtgt
    33901 ggggccagat gtgccggtgg gcatctgcat ggaacgctct atagatttgg tcgtgggact
    33961 gttgggtatt ctgaaagctg ggggagctta tgtgcccctt gacccagact atccgcaaga
    34021 acggctgtct tggatattag aagatgtaaa gccgctagtc ctgttaactc agtcgcggtt
    34081 agtgaatcag cttccacgga cgaaaatcgt ttgtttagac gcagagacag caactattgc
    34141 tcaggaatct acagaaaatt tggtgccgga agttaaagct gaccacctcg cttatatcat
    34201 gtacacttcc ggctctacag gcaaacccaa gggagtgagc attattcatc ggggggttgt
    34261 acggttagtt caagcaacca actatgttgc tctcaccgca gcagaagtct ttctccagtt
    34321 ggctcctatc tcctttgatg cttcgacatt tgaaatttgg ggtagtttgc tcaatggcgc
    34381 taagttagtg attatgccca tccccaaggg aactttagag gaattaggac aggtaattag
    34441 ggaaaaccaa gtaaccacaa tctggctgac ggcgagttta ttccatctga tggtggatga
    34501 gcggttggat gatcttaaat cggtgcggca actgttggct gggggggatg tgttatcagt
    34561 cacccatgtg caaaaggtat tccaacactt gccccattgt cggctgatta acggttacgg
    34621 gcctaccgaa aatacaactt ttacctgctg ctttccaatg actgctgaaa ctcagattgg
    34681 ggcatctgta ccgattggtc gcccgattgc taataccctg gtttatattc tcgacgcgaa
    34741 tcttcaacct gtgcccattg gtgtttgggg tgaattgtat atcggtggtg cgggtttagc
    34801 tcagggttat tttaatcgtc ctgatttgac tcaggagaaa tttattgcca atccctttga
    34861 ggattcaaaa ttcaatcgtc tttataagac aggggattta gcgcgttatc tgccagatgg
    34921 caacattgag tttttgggac ggatagatca gcaggtgaaa atacgcggtt ttcgtattga
    34981 attgggcgaa atcgccgcta tccttgctaa ccatccccag gtaaaacagg ctgtggcgat
    35041 cgcacataca gatacatcag gtaacaagcg cctcgttgcc tatttcgttc ctgatgggga
    35101 gaagccaagc agcagcgaat tacgtaactg gctgaaaaag aagatccccg actatatgct
    35161 gccagaggtt tttgtctgct tagagagcct gccgttgaac tctaacggca aagtagaccg
    35221 tttcgctcta ccactgcctg atctagaact ttatcgctct gtcaagtttg ttgccccccg
    35281 aactgcaact gaacaagcga tcgctaatat cgtagctgaa gttctcaaca ttgagcaagt
    35341 cggtattgat gacaactttt ttgaactcgg cggtaattcc ctcaatgcca atcaagtaat
    35401 ttctcgctta cggcagactt ttagggttga gttacccctg cgtaacttac tggaggaacc
    35461 gacagttgtt gagttagcca ccagcatgga tcaaattcgg gcaaccgtgc aaaaactaca
    35521 gtctagccct agcgatttac tggaagaccg ggaggaaatt gaagtatgaa accgattcaa
    35581 gagtttttgt ccgagctagg gaatctgaat attaagctct gggtagaggg tggggttaag
    35641 ctgcgctgta atgcccccag tggcacgtta acgccagaaa tccggactca acttagcgat
    35701 cgcaaagcag aaattatcac gtttcttcag caggtgaatc tggatgctga tgatttgcta
    35761 gattcgattc ctgtcgtacc gcgagacggg atattacccc tgtcctcaac acaacagcga
    35821 ctgtggtttc tagaccaaat ggaaggtgct agtgctactt acaatatgcc tgctgccata
    35881 gagatgcacg ggattttgca aattgaaatg ctagagcgat cgcttgtcga aatcgtccgt
    35941 cgtcacgaag tcctgcgaac cagctttcag caactcaatg gcacatcaac ccaggtgatt
    36001 tcagctgaag ccaccatcat tttacccgtg gtggacttgc aaaaattccc cccagaggaa
    36061 caagctaacg aagtcaaggg gttaataatt caggaagcag agaaaccctt tgacctcaaa
    36121 caagcgccct tattgcgagt caccctgttg cgtttaagtg aaaaatccca tgtgttgctg
    36181 ttaaatatgc accacatcgt ctcagatggt tggtcaattg gcatcttcat ccaagaatta
    36241 tcagccctat attcagccta ctgtgcagga aaaccctcac cattagcaga attacccatc
    36301 cagtatgcag acttcgccca atggcaacaa caatggttgc gtggcgaagt attagacaca
    36361 aaactcaaat actggaaaca gcagctagca gatgcaccac cactgttaga actacctaca
    36421 gatagacccc gtccagcgat tcagaccttc cggggtagca gtcgagagtt tctgcttccc
    36481 atagagttaa cagagaaact caaacgccta agtcaacagt caggagtcac actgtttatg
    36541 actctggaag cggcgtttgt caccttatta catcgttaca gcggtcaaga agacatcctc
    36601 ataggtactc ccattgccaa ccgcaatcaa cgagaaatcg aatccttaat tggctttttt
    36661 gtcaatacct tggtactgcg aacaaatcta gccggaaatc ccagttttgc agaattatta
    36721 aagcaagtgc gacaagtagc gctagatgcc tacacgcacc aggatgtgcc ctttgagcag
    36781 gtagttgagg cactgcaacc agcgcggaat cttagccata caccactgtt ccaagtgctg
    36841 tttgccttgc agaatgcccc agtgggagag ttggaattgc cggggctgag attgaaaccg
    36901 ttaccaatag aggcagtcac ctccaagttt gatataactt tgtcgatgga agaaacaccc
    36961 caaggacttt tggggaattg ggaatacagc actgatttat ttgatgggga aaccatctct
    37021 cgcatggctg ggcattttca gaatttgctg gcagcggttg tcgcaaatcc tgcggagcct
    37081 attcagcaat taccgctact ttcagattct gagaggcaac agttgttagt agattggaac
    37141 tctacaacag ttgattatca aactaattta tgtctgcatc aatggtttga gcaacaagta
    37201 caacagacac cgttggctgt ggcagtggtg ttcgataata ctaatttaac ctactcacag
    37261 ttgaataatc gtgcgaatca attagcgcat tatttgcaaa ccttgggtgt agcgcccgat
    37321 gtcctagtgg gcatttgtgt ggaacgttcc ctagagatgc ttgtgggact gttggggatt
    37381 ctgaaggctg gtggtgctta tgtgcccctt gacccagaat atccccaaga gcgcttggat
    37441 tatatgttgc gcgattctca ggtttcagtg ctgctcacac aatcgcaatg cctgaaatcc
    37501 ttgcctgatg tggataattt gagaatctgc ttggatacag attgggaaat cattgaaact
    37561 caaagtcagg agaatccagt cagcgaagtt gaccccaata acctagcgta tattatttat
    37621 acttccggtt cgacaggcaa gcccaaaggc gtattagtca accataaaaa tgttacccgc
    37681 ttattaggag ccacccagca ctggtttaac tttaaccaat cagatgtatg gacattattc
    37741 cactcttatg cattcgactt ttctgtttgg gaaatttggg gtgcattact gtatggtggg
    37801 cggctagtag tcgtaccctt ctgggtgagc cgcgactcca acgccttcta taacttgcta
    37861 tgtgttgaac aggttaccgt cctcaaccaa acaccctcag catttcggca attgatttgg
    37921 gtagaggagc aagaagaacg agcaacatct aacctgaaat tgcgctgggt agtctttggg
    37981 ggagaagctt tagacccatc tagtttaata ccttggttta agcgtcatgg ggatagtatt
    38041 ccgcaactgg taaatatgta cggcatcact gaaaccacag tgcatgttac ctatcgtccc
    38101 atatccatcg ccgataccga aagccgcagc agtgtcattg gtgccgcaat tcccgacttg
    38161 caaatgtaca ttctggatga acaacttcag ccggtaccga taggggtgcg cgggcagatg
    38221 tatgtggggg gtgcaggtgt agcgcggggc taccttaacc gtccagagtt aacagcagag
    38281 cgttttatta aaaatccctt tagggatgat tcagaagcga gactatataa aacaggggat
    38341 ttggcgcgtt ctaagccaga tggaagtatt gagtatctgg gacgcatcga caatcaagtc
    38401 aagctgcgcg gcttccgcat agaattggga gagattgaaa gtgcgatcgc acaacatccc
    38461 caaataagag aaacagtagt cctcgtccga gaagatatcc ccggagataa acgcttagtt
    38521 gcctacttcg tgcccaacgc tgaagcacca acgagtagcg ggatgcgtga ttacctcaaa
    38581 caacagctac cagattacat gattcccgct gtgtttgtcg gactcgatag cttccccctc
    38641 accaataacg gtaaactcga tgttcgcgcc ctcccaatcc ctgaccaaag ccgacccgaa
    38701 ttagaaacat acattccccc ctccacccca gaacaagccc tactagcagg agtttgggca
    38761 gaagtactag gggcagaaaa agttggtatc aacgataact actttgaatt aggcggcgac
    38821 tccattcgca gtattcagat tagggcaaaa gctaatcaag tcgggctaga tttttctctc
    38881 cagcagcttt ttcaatatca gaccattgct gagttagcta gtgttgtcag ccgtgaagtc
    38941 agtatcgcac ctatctccaa aaccgcaccc ttcagcttga ttgctgcgga ggagcgactg
    39001 aaactcccag aggatgtaga ggatgcttat cccctagccg cacttcaagc agggatgatt
    39061 tttcatagcg aatacaatga aactagccca atttaccatg atgtattcac ctttcacctg
    39121 tgcgctgccc tcgacctaga gagatttaac gcagcaatcc agcagataat tgcgcgtcat
    39181 gcagtattgc gaacaagcat tgccctgacg ggatttgagc agccattgca actggtgcat
    39241 cagacagtag agacaccctt gcaggtagaa gacatcagcc tgatgtcaaa agaccagcaa
    39301 gaagcagtca ttgatgcttg gatggaagcc gagaaaaatc gacattttga ttggaaaata
    39361 ccgcccttat tgcgctttca tattcatcgc cgcagtgaag aaacttttaa tttaagtttt
    39421 agtttccacc atgcaattct tgacggatgg agcgttgcat ctttactcac agaattgttg
    39481 cagaaatact tctcattaat gggtcaagaa gttgttttac aaccatctcc aaatctagcc
    39541 tttgccgatt ttatcgcatt agagcaaacc accctgcaat ctcaagacag ccaacagtat
    39601 tggactgagc aactaagcga cttgaatgtg atttctttgc cgcgattacc tgaatctaaa
    39661 tcagccgcga agggacaatt gggtgtccaa gaagtgccaa tttccccaga aatatcagca
    39721 ggattaaagc agctagcgca gaatgcagga gtacccatta agagtgtttt actagctgct
    39781 catctacgag ttttaagctt ggtgagtaac cagacagatg tcctcacagg cttagtctcc
    39841 aatggtagac cggaaaatgc agatggagaa agggtgttgg ggctgttcct gaatacattg
    39901 cccttgcggt tgcatttaaa tggcggcact tggctagact tgatcagaga aaccttccaa
    39961 gcagaacagg gaatccttcc tcaccgtcgc taccccctag cagaattgca aaaaatgtgc
    40021 ggggggaaat cattatttga gaccaatttt aactttgtac atttccacgt ctatcagagc
    40081 attttggggc tggaaggtct ggaagtttta ggacataagg tatttgagca aaccaatttc
    40141 accttagtag ctaactttag cttggatttg atttcgtctc agattaactg tatcctcaac
    40201 tatgacgcta ttgaattggg tgaggaacag gtcagagcaa ttggtggtta ttatggcaaa
    40261 acccttgagg cgatggtttc tcaacctgat gagcgttatg aattgcgatc gcttctctcg
    40321 gactcagaac gccatactct actagtagaa tggaatcaga catcctctga ctatcctgcc
    40381 catttatgtc tgcatcaatt aattgagcaa caagtacaac gcacacccga tgccgtagca
    40441 gtagtatttg ctgaccaaca cctcacatac tctcagttga ataatcgtgc taatcaatta
    40501 gcacaccact tgcaatcttt gggtgttgct cccgatgttc tggtgggtat ttgtgtagaa
    40561 cgttcgctag aaatgctggt cggtttattg ggcattatga aagctggtgg tgcttacgtc
    40621 cccatagatc cagcttatcc ccaagagcgc ctgcgctata tgttgggtga tgctcaagta
    40681 tcggtgttat taacacaatc tcacctgctg gatatcttgc cagaagaaaa tcccattttg
    40741 tgtttagaca cagattggca aattatcgct catcagagtt gtgaaaatgt agtctctcag
    40801 gtacaacccc agaatttagc atacataatt tacacctccg gctccacagg tcaacccaaa
    40861 ggggcaatga ttcagcatca agggctggta aattatcttt attggagtat tgaagcttat
    40921 gccgttgccg atggctgtgg cgcacctgtc aactcttcct tcgcctttga tgccaccatt
    40981 acctgtcttt tcacaccttt aatggtgggc ggacaagtta tgatgctgcc agaacagcaa
    41041 aagattgaag cactttgtga cgttttgcga ggacgtcatc agtttagctt agtcaaactc
    41101 accccagccc atttagaatt actcaatcag ctactgctgc cagaagaact accagaatcg
    41161 gctttggcat tagtcatcgg tggtgaagcc ctcctcggca aaaccctgca attttggcaa
    41221 caatatgcgc caaacacccg cctaattaat gaatatggcc ccacagagac ggttgtggga
    41281 tgcagcatct acgaagtgac gccagaaaca tccctgacag aggggatttt gattggtcgt
    41341 ccgatagcta atacccagct ttatatcctg gataaattct tgcaaccggt gcccattggt
    41401 gtcgggggcg aactctacat tggtggggct ggtgtagcgc gaggatactt taaccgtcca
    41461 gagttaaccc aagagaaatt cattcccaat cctttcagta aaaaccgaga agccagactg
    41521 tataagacag gagacttagc ccgttatttg ccagatggta atattgaata tctgggacgc
    41581 attgacaatc aagtcaagct gcgcggcttc cgcattgaac ttggggaaat agaaaatgct
    41641 ttagcacaac atccccaagt aagagaaaca gcagtcttgc tgcgagaaga catccccggt
    41701 gacaaacgcc taatcgccta tttcgtagct gacaccgaag caccaaccag cagcgacctg
    41761 cgagattacc tgaaaaagcg gctccctgac tacatgattc ccgcaggctt tgtcgaactc
    41821 gaaaccttcc ccctgacaaa caacgggaaa gtagaccgcc gcgccctacc agcccccgac
    41881 ctagaaacca gtaactccag taaccttgtt tccccccgga cacccaccga agaaatcatc
    41941 gccaacatca tcgctgaagt actccgggtc aaaaatctca gcatctacga caacttcttt
    42001 gaaatcggcg ggaattcact cctcgccacc caagttatta ctcgcttgcg ggaaactttc
    42061 caaatagaat tacctctgcg ttatctattt gaatcgccca ccgtcgccga acttgatgcc
    42121 gccataacta ctttccgcca aacagcctca ggactaagca caccagaact cacagccatc
    42181 aatagagaaa atcaacccct gtccctgtcc tgggcacagc agcgactgtg gtttatcgac
    42241 caactcgaag gcgctagtgc ggtgtataat atgcccgctg ccgtgcagat ggacgggatt
    42301 ttgcagattg aagtgctaga gcaatcgctt gccgaaatcg tccgtcgtca cgaagttctg
    42361 cgaaccagtt tccatcagct taatggcaca tcagttcagg tgatttcatc tgaagccacc
    42421 atcaatttac ctgtcgtaga tttacaggga gaatcaacaa cagaagtaca aaaattaata
    42481 actttagccg cagagaaacc ctttgacctc aagcaggctc ccttattgcg agtcacgcta
    42541 ttacgtttag gggaaaaatc tcatctgttg ctgctaaata tgcaccacat cgtctcagat
    42601 ggttggtcaa caggcatctt catccaagaa ttatcagccc tatattcagc ctactgtgca
    42661 ggaaaacctc accattagca gaattaccca tccagtatgc agacttcgcc caatggcaac
    42721 aacaatggtt gcgtggcgaa gtattagaca caaaactcaa atactggaaa cagcagctag
    42781 cagatgcacc accactgtta gaactgccta cagatagacc ccgaccagcg attcaaacct
    42841 tccggggtag cagtcgagat tttctgcttc ccatagagtt aacagagaaa ctcaaacgcc
    42901 taagtcagca atcaggagtc accctgttta tgactttaga agcagcgttt gtcagcttat
    42961 tacatcgtta cagcggtcaa gaagacatac ttataggcac gcccattgcc aaccgcaatc
    43021 aacgagaaat cgaatcctta attggctttt ttgtcaatac cttggtattg cgaacaaatc
    43081 tagccggaaa tcccagtttt gcagaattat taaagcaagt gcgacaagta gcgctagatg
    43141 cctacacgca ccaggatgtg ccctttgagc aggtagttga ggcactgcaa ccagcgcgga
    43201 atcttagcca tacaccactg ttccaagtgc tgtttgcctt gcagaatgcc ccagtgggag
    43261 agttggaatt gccggggctg agattgaaac cgttaccaat agaggcagtc gcctccaagt
    43321 ttgatatcac tctgtcgatg gaagaaacgc ctcaaggact gttggggaat tgggaataca
    43381 gcactgattt gtttgatggg gaaactatct ctcgcatggc tgggcatttc cagaatttgc
    43441 tcacagcaat tgtcgcaaat ccggcggaga ctattcagca attaccgcta ttgagtaatt
    43501 cagaaagaca gcaattgtta gtagattgga actcgacaac agttgattat caaactaatt
    43561 tatgtctgca tcaatggttt gagcaacaag tacaacagac accattggct gtggcagtgg
    43621 tgttcgataa tactaattta acctactcac agttgaataa tcgtgcgaat caattagcgc
    43681 attatttgca aaccttgggt gtagctcccg atgtcctagt gggcatttgt gtggaacgtt
    43741 cccttgatat ggttgtggga ctgttgggga ttctgaaggc tggtggtgct tatgtacctc
    43801 ttgacccaga atatccccaa gagcgcttag agttcatgct tgatgactcc caagtttcag
    43861 tgttgctcac acaatcgcag tgcctgaaat ctttgccaga agttcaagcc cagataattc
    43921 ccttagatac cgactgggaa atcattgaaa ctcaaagtca ggagaatcca gtcagcgaag
    43981 ttgacccaaa taatctggcg tatattattt atacttccgg ttcgacaggc aagcccaaag
    44041 gcgtgttagt caaccataaa aatgttaccc gcttattagg agccacccag cactggttta
    44101 actttaacca atcagatgta tggacattat tccactctta tgcattcgac ttttctgttt
    44161 gggaaatttg gggtgcatta ctgtatggtg ggcggctagt agtcgtaccc ttctgggtga
    44221 gccgcgactc caacgccttc tataacttgc tatgtgttga acaggttacc gtcctcaacc
    44281 aaacaccctc agcatttcgg caattgattt gggtagagga gcaagaagaa cgagcaacat
    44341 ctaacctgaa attgcgctgg gtagtctttg ggggagaagc tttagaccca tctagtttaa
    44401 taccttggtt taagcgtcat ggggatagta ttccgcaact ggtaaatatg tacggcatca
    44461 ctgaaaccac agtgcatgtt acctatcgtc ccatatccat cgccgatacc gaaagccgca
    44521 gcagtgtcat tggtgccgca attcccgact tgcaaatgta cattctggat gaacaacttc
    44581 agccggtacc gataggggtg cgcgggcaga tgtatgtggg gggtgcaggt gtagcgcggg
    44641 gctaccttaa ccgtccagag ttaacagcag agcgttttat taaaaatccc tttagggatg
    44701 attcagaagc gagactatat aaaacagggg atttggcgcg ttctaagcca gatggaagta
    44761 ttgagtatct gggacgcatc gacaatcaag tcaagctgcg cggcttccgc atagaattgg
    44821 gagagattga aagtgcgatc gcacaacatc cccaaataag agaaacagta gtcctcgtcc
    44881 gagaagatat ccccggagat aaacgcttag ttgcctactt cgtgcccaac gctgaagcac
    44941 caacgagtag cgggatgcgt gattacctca aacaacagct accagactac atgattcccg
    45001 ctgtgtttgt cggacttgat agcttccccc tcacagccaa cggtaaactc gatgttcgcg
    45061 ctttaccaat tcctgagcaa agcaaacctg aagaaacata tattccaccc tctaccccag
    45121 aacaaacctt actagcgggg gtttgggcag aagtactagg ggcagaaaaa gttggtatca
    45181 acgataatta ctttgaatta ggcggcgact caattcgcag tattcagatt aaggcaaaag
    45241 ctaatcaagt cgggctagat ttttctctcc agcagctttt tcaatatcag accattgctg
    45301 agttagccag tgttgtcagc agtcaaccga atattttccc catccccagc agcaaaccat
    45361 tcagcctaat atcggacaca gaccagttaa agctgccaga ggatgtagag gatgcttatc
    45421 ccctagcagc actacaagca gggatgatct ttcatagcga atacagcatt gatacggcga
    45481 tttaccacga cgtttttagc ttccatctgc gagctatcct cgatatagcc aagtttaagg
    45541 acgccatcca acaggtagta aatcgctatg cagtattgcg taccagcttt gccctgacag
    45601 gatacgagca gccattgcaa ctggtgcatc agacagtaga gacacccttg caggtagaag
    45661 acatcagcca tttagatatt tccgcccaaa aagcggttat tgatgactgg attaccgcag
    45721 aaaaatatcg gcattttgat tggaagatag caccaatgtt gcgcttccag attcatcgcc
    45781 gcagtgggga aacctttagt ttaagtttta gtttccacca tgcaattctt gacggatgga
    45841 gcgttgcatc tttgctcaca gaattgtggc agcaatattt ctcattactt ggacacacag
    45901 tggcgttgca accgtcacca acaacaacat tccgcgattt tgtagcatta gagcaaagcg
    45961 ccctgcaatc tcaagacagc caacagtatt ggactgagca acttagggat ttcaatgtta
    46021 ctgagttgcc gcgattgcct gaatcggctc gtactgggga gagcgagaaa ctgggagagc
    46081 gggaagtttt gatttcacct gaactttcag aagggttaaa gcagcttgcg cggaaggcag
    46141 gagtaccaat taagagtgtt ttactagctg ctcatctacg agttttaagc ttagtgagta
    46201 atcagacaga tgtcctcacg ggcttagtct ccaatggtag accggaaaat gtagatggag
    46261 aaagggcact gggactattt ctgaatacct tgcctttgcg gttgcatctc aatggcggta
    46321 cttggctgga cttggtacgg gcaactttcc aggcggagca agcaaatatc ccccaccgtc
    46381 gctatccctt agcggaaatg caaaggatgt gcgggggaca atcgttgttc gagactaatt
    46441 ttaactttac ccatttccac gtttatcagg gcattttggg gctggacggt ctggaattaa
    46501 tagagaatac gttatttgag caaaccaact ttgcgttagt cgctaatttt tctttggatg
    46561 tgtcttcgtc cgatgtgagg ttaattctta gctatgacgc cattgaattg ggtgagtcac
    46621 aaatcaaggc aattggcagt tattatggca aaaccctgga ggcgatggtt tctcaaccgg
    46681 atgagcgtta tgaaatgcga tcgctcctct cggactcaga acgtcatcag ttactagtag
    46741 aatggaatga tactcaggct gactatcctg ctcatttatg tctgcatcaa ttatttgagc
    46801 aacaagtaca acgcacaccc gatgctgtag cagtagtatt tgctgaccaa cacctcacat
    46861 actctcagtt gaataatcgt gctaatcaat taggacacta tttgcaatct ttgggtgttg
    46921 ctcccgatgt tctggtgggt atttgtgtag aacgttctct agagatgctt gtcgggttat
    46981 tgggcattct gaaagctggt ggtgcttatg tccccctaga tccagcttat ccccaagagc
    47041 gcctgcggta tatgttggac gattctcaag tatcggtgtt attaacacaa tcgcacctgc
    47101 tggatatctt gccagaagga aattccattt tttgtttaga tacagactgg caacttatcg
    47161 cccagcaggg tacggagaat gtatcttcat taggcacaag atacgaagaa ataggagttt
    47221 tacgaaccgc caagacgcca agaacgccaa gaaatgaaag gcgctgcgta agtcctgaag
    47281 tagaatcatc caacctagcc tatataattt acacttccgg ctctacaggt caacccaaag
    47341 ggacaatgat tcagcatcaa ggggtggtaa attatctcag ttggtgtacc caagcttatg
    47401 cgatcgctga tggctgtggc gcacctgtgc aatcttcctt cgcctttgat gccaccatta
    47461 ccagtatttt ctcaccttta attgtgggtg gacaagttgt gctgctgcca gagaaacaag
    47521 aaattgaagc tctctgtgag gttttgcgag ggcgtcatca gtttagctta gtcaaactca
    47581 ccccagccca tttagaatta ctcaatcagc tactgctgcc agaagaacta ccagaatcgg
    47641 ctcaggcatt agtcatcggc ggtgaagccc tcctcggcaa aaccttgcaa ttttggcaac
    47701 aatatgcacc aaacacccgc ctaattaatg aatatggccc cacagagacg gtggtgggct
    47761 gttgcatcta tgaggtgacg ccggaaacat ccctgacaga gaaaattttg attggtcgcc
    47821 cgatagccaa tacccagctt tatatactag attcccatct ccaaccgcta cccattggtg
    47881 tcgggggtga actctacatt ggtggggcgg gtgtagcacg gggatacctc aaccgtccag
    47941 agttgacagc agaacgtttc atcagaaacc cctttagaaa tgacccagaa gcaaggctgt
    48001 ataaaacagg agacttggcg cgttatttac cagatggaaa tattgaatat ctgggacgca
    48061 tcgacaatca aatcaagctg cgcggcttcc gcattgaatt gggcgaaata gaaaatgctt
    48121 tagcacaaca tccccaagtc agagaaacag cagtcttgtt gcgagaagac atctcaggag
    48181 acaaacgcct aatcgcctat ttcgtagctg acaccgaagc acccacgagt agcgacctgc
    48241 gtgattacct gaaaaagcaa ctcccagact acatgattcc cgcaggcttt gtcggacttg
    48301 aaaccttccc tctcaccgct aacgggaaag tagaccgccg cgccctaaaa gcccccgacc
    48361 tagaaaccag ttccagtaac tttgtttctc cccgcacacc caccgaagaa atcatcgcca
    48421 acattatcgc cgaagtcctc cgtgttaaac ggataagcat tcatgacaac ttctttgaaa
    48481 tcggcgggaa ttcactcaat gcaacccaag ttatcactcg cttgcgggaa actttccaaa
    48541 tagaattacc tctgcgttat ctatttgaat cgcccaccgt cgccgaactt gatacagcca
    48601 taactacttt ccgccaaaca gcttcaggac tgagtacacc agcactcgta ccagcaaaga
    48661 gagaaaatca acccctatcc ctgtcctggg cacagcagcg actgtggttt atcgaccaac
    48721 tcgaaggcgc tagtgcggtg tataatatac ccgctagcgt ccaaatggac gggattcttg
    48781 atgtcgtcgc cctcgaacaa accctagccg aaatcgtccg tcgtcacgaa atcctgcgaa
    48841 ccagtttcca tcagcttaat ggcacatcag ttcaggtgat ttcagccgaa gctacaataa
    48901 atttgcctgt cgtcgattta cagggagaac caacaacaga agtacaaaga ttaatcactt
    48961 tagccgcaga gaaacccttt gacctcaagc aggctcctct attgcgagtc acgctattac
    49021 gtttagggga aaaatctcat gtgttgctgt taaatatgca ccacatcgtc tcagatggtt
    49081 ggtcaaccgg catcttcatc caagaattat cagcgttata ttcagcctac tgtgaaggaa
    49141 aaccctcccc actaacagaa ttacccatcc agtatgcaga cttcgcccaa tggcaacaac
    49201 aatggttgcg tggcgaagtc ttagacacaa aactcaaata ctggaaacag cagctagcag
    49261 atgcaccacc gctgttagaa ctacctacag atagaccccg tccagcgatt cagaccttcc
    49321 ggggtagcag tcgagagttt ctacttccca tagagttaac agagaaactc aaacgcctaa
    49381 gtcaacagtc aggagtcaca ctgtttatga ctctggaagc ggcgtttgtc accttattac
    49441 atcgttacag cggtcaagaa gacatcctca taggtactcc cattgccaac cgcaatcacc
    49501 gagaaatcga atccctaatt ggcttttttg tcaatacttt ggtgttgcgg acaaatttag
    49561 ccggaaatcc cagttttgca gaattattaa agcaagtgcg gcaggtggcg ctagatgcct
    49621 atactcacca ggatgtaccc tttgagcagg tagttgaggc actgcaacca gcgcggaatc
    49681 ttagccatac gcccctgttc caggtgatgt ttatcttgca gaatgcaccg atgggagatt
    49741 tggaattacc agggttgcat ctaacacctt tgtcgatggg ggctgtaagt gccaagtttg
    49801 atttaacttt gtcgatggaa gaaacgcctc aaggactgtt ggggaattgg gaatacagca
    49861 ctgatttgtt tgatggggaa accatctctc gcatggctgg gcatttccag aatttgctag
    49921 cagcggttgt agcaaatccg gcggagacta ttcagcaatt accgctactt tcagattctg
    49981 agaggcaaca gttgttagta gattggaatt ctacaacagt tgattatcag catcatttat
    50041 gtctgcatca atggtttgag caacaagtac aacaaacacc agatgctcta gcagtggtgt
    50101 tcgataatac tagtttgacc tactcacagt tgaataatcg tgcgaatcaa ttagcgcatt
    50161 atttgcaaac cttgggtgta gcgcccgatg tcctagtggg catttgtgtg gaacgttccc
    50221 ttgatatggt tgtgggaatt ttagggattc tcaaagctgg tggtgcttat gtgcctcttg
    50281 acccagaata tccccaagag cgcttggatt atatgttgcg cgattctcaa gtttctgtgc
    50341 tgctgacaca atcgcaatgc ctgaaatctt tgcctgatgt ggataatttg agaatctgct
    50401 tggatactga ctggggaatc attgaaactc aaagtcagga gaatccagtc agcgaagttg
    50461 caccaaataa cctagcgtat attatttata cttccggctc tacagggaaa cctaaggggg
    50521 tagcgatcgc acattgcagt cctgtagcgc tggtggcttg ggcgctcaag gtctttactc
    50581 ctcagcaatt ggcaggggtt ttggcttcga cttccctctg tttcgacctc tccattttcg
    50641 agatgtttgt tcctctcagt tgcggcggta tggtgattgt ggcggaaaat gcactgcatc
    50701 tgcctgagtt aattgccttt gaacaggtca cgctgattaa tacagtcccc tctgcgatta
    50761 gggaattact caacgggcca ggactacccc agagcctagc tacagtcaat ctggcggggg
    50821 aaccgttgcc gctgtcactg gtgcaacaac tgtatcagcg ccagactatc caccaggtat
    50881 ttaatctcta cgggccatcg gaaacgacca cctactcaac ttttgccctg tgtaaccgag
    50941 gagatagttt agctccaact atcggccggg cgatcgcaaa tacgcaaatc tacattctgg
    51001 atgctctcat gcaacctgtg ccaattggcg tgcgtgggga actttacatt ggtggtgcag
    51061 gggtcgcacg gggctatctt aaccgtcccg aattaaccgc agaaaaattc atccccaacc
    51121 cctttgaaaa ttcaaaattc catcgcttgt acaaaacagg tgacttagcc cgttaccttc
    51181 ctgatggcaa cattgaatat ctcggtcgca tcgataatca agttaagctg cgagggttcc
    51241 gcattgaatt gggagaaatt gaaactgcga tcgcattaca cccacaatta aaacaagcag
    51301 ttgtcagcat tcgtgaagac caacctggta tccgtcgcct agtcgcctac ctagtggctg
    51361 aggtcgaaac ccccagcagc agcgaactgc gtagctttct caaacagcaa ctgcctgatt
    51421 acatggtgcc tgggattttt gtcttcctag atgccctacc cttaaccccc aatggtaaag
    51481 ttgatcgccg cgccctccca gcccctaacc tcgaacagaa tcgcccaatc agccttgttc
    51541 cagctagcac agccatcgaa gaaagcttag tcaccatctg gagcgaaata ttagggctaa
    51601 aacaagtcag cattcacgat aatttctttg acttgggtgg agattccatc atcagcattc
    51661 aaattatcgc ccgtgcggct caagtgggag tacaactgac gctgaaacag atatttcaat
    51721 atcaaactat tgctgaattg gcgacagtct gcggcactat tactgtccaa gcggaacaag
    51781 ggttagtgac tggggaagtt cccttgaccc caattcagca gtggttctta gagcaaaatt
    51841 cccctcatcc agactacttc aaccaatctg tgctgctgga agtggctcca gacctgaaac
    51901 cggaattatt gcagcaagtt gtgcagcagt tactagagca acacgatgca ttacggctca
    51961 gattcgggcg caacgattcc cagtggcagc agataaacag tgatacatct gatatagtac
    52021 ctttccaagt ttttgattta tcagcacttg ctcatgaggc gcaacaagca gcgattgaga
    52081 ccacagccgc tcaactgcaa gggagtttaa atctatcaga ggggccattg atgcgggtgg
    52141 cgctgtttaa attggggagt gattcccttg atcagttact aatcatcatc catcacctcg
    52201 ccgtggatgg cgtctcgtgg cggattttac ttgcagactt atctactgcc taccaacaga
    52261 ttagccgtgg agaagccatc caactgccac ttaagacaac ttccttcaaa gattgggcaa
    52321 ttcgcctcca agactatggg cgttcgcctt cccttgctgc tgaattggat tattggctgg
    52381 cttcatcccg cgctaacgtt gctcctctgc cagtggacta tcccgatggc aaagaatcta
    52441 acaccgttgg taacactgct caagtatcgg tttctctcag tgagagtctt acccatgccc
    52501 ttttgcagga agtgccacag gcttacaata ctcaaattaa cgatgtcttg ctgactgctt
    52561 tattgcaaag ctttgcccca tggacaggtg caaattcagt cttagttgat ttagaaggtc
    52621 acggacggga agaactgttt gaggaaatca acctcagccg caccgtgggc tggtttacca
    52681 ccatctaccc cctgctgctg gaacttgggg aggagaatca gccaggagcc gccctcaagt
    52741 gggttaagga gcaattgcgg acggtaccac aacggggtat tggttacggg gtgttacgct
    52801 atctcagtgg cgattccaac attcgccagc aattacaggc attgcctcaa gccgaggtat
    52861 gtttcaacta cttgggacaa ttcgatcact tgcaaacaga agggatcatc caggggtttt
    52921 cccaagcatc cagcggagct actcaaagtc ctttgtccca tcgtcgctat ctcttggaag
    52981 tcaacggact tgtggccgaa ggtaagctac aactcaactg gacttatagc aaagtggtgc
    53041 atgagcggag gacaattgag cgtttagcca atgaatttat caccgtattg caagggctga
    53101 ttattcattg tcaatcgcca gaagcaggtg gatttacccc ttctgatttt ccgatagctg
    53161 agttgagtca agctgatttg gatgagttgt tggcagaaat caattagata ggacttacgg
    53221 acactctacg aattcttggc gttctacagc cctatgccta acggcaggct tacgccaacg
    53281 ggcatcgctg cgcgcgggcg ccttggcggt tcgttaaatt aagcttcttg gctatttttg
    53341 cgtaagtcct gttagagtca tccacaaaat aacaggcgtc tcgcctgttc tacggaatat
    53401 agagttagca caaggtattt atgacagtct ccgaccaaac aaacaaaagc aaaaatgttg
    53461 ccgctattta ccccttgtct cctatgcagc aggggatgct gtttcatacc ctttatgctc
    53521 cagagtcggg agtgtatttt gagcagttta gttgcacttt ggggggaaaa ctaaatgtag
    53581 ctctgtttga acaggcttgg caaaaagtgg ttgagcggca tccggtttta cgatcgctgt
    53641 ttgtttggga aaaccgcaaa aagcccctcc aggttgtgcg gcatcaggtc aatttacctt
    53701 ggattcaaca tgattggcga tcgctttctc cttctaagca acaagggcaa ttagaagaat
    53761 ttctgattag cgatcgcacc caaggttttc aactagatca agcgccgtta atccgctgtg
    53821 ctttgattcg tttgagcgaa gaaacatacc aatttatcgg cagttttcat cacttgttgc
    53881 tagatggttg gtcgctaccc atcttattcc aagaagtttt tggcttttac gaggcttgga
    53941 atcgtggtga taatttatcc ttagctacac cccgtccttt ccaagattac attggttggt
    54001 tgcaacggca ggatctatca atagctgagg cattttggcg tcgtaccctc caagggttta
    54061 cagcaccaac tcccttggga gtagaccgga tgataaagtt tgatactcat catcaaggta
    54121 gtttccacga gcagcctttt cagttatcag caacagcaac ggctgctctc caaaggtttg
    54181 cccaacagca tcgccttacc gtttctacct tggttcaggg aacttgggca cttttgctca
    54241 gtcgctacag tggtgaatcg gatgtcgttt ttggggcaac agtatcaggt cgcccaccga
    54301 ctttgccagg agcagaatcg atggtgggac tgttcatcaa taccttacct gtacgggtac
    54361 aaattcctga agatgctcaa actttgcctt ggctccagca gttacaatcc cagcaggtgg
    54421 agcaggatca gtattcctac agtttcctag tggatattca aggctggagc gaaataccac
    54481 gaggaatgcc cttgtttgag agcatcgttg tgtttgagaa ttaccccgtg gctgcggctt
    54541 tgcaagagcc attagacagc ttgcaagtgg ataatgtgcg tgcttatgaa accaccaatt
    54601 atcccctgac tttggtggct gcgtctcatc aagagttgta tggcagaatc gtttacgatc
    54661 gcgatcgctt tgaagccgat gcgatcgccc gcatggctaa ccatttccaa aatttgttaa
    54721 tagccatatc cacccagtct gagcaaccta ttaaacaatt acctctcctg gacgatgctg
    54781 aaaaacagca gttgttgcaa gcatggaacg ctggtaaagc cgagtatccc tctgagcaat
    54841 gcttgcatca atggtttgaa caacaggtag agcaaacacc aaatgcgatc gcagtcgtgt
    54901 ttgataacca aagtctcacc tacgcacagt taaatactcg cgctaatcaa ttagcacacc
    54961 acttgcaatc cttgggagtg gcacctgaga ccttagtggg tatctgcgtc gaacgctccc
    55021 ttgatatggt agttggactt ttgggcattc tcaaagctgg aggagcctat ctcccccttg
    55081 acccagacta tcccgcagat cgtttggaat tcatcctcca agatgctcag gtatcggtgc
    55141 tgttaacaca gtcccaatgg ctaaattcct taactgaagt gtcagcccag acagtctgct
    55201 tggatactga ttgggaagct atcagcgctt ttagtcaaga gaatcctgta aatcaagcaa
    55261 cgcccaacaa tttagcttat gtaatttata cctccggctc aacaggtaaa cccaagggag
    55321 tattagtcaa tcacgccaat gttacccgcc ttttcacagc tacccaaagc tggtttaact
    55381 tcaacgaaag cgatgtctgg acactattcc actcttacgc cttcgatttt tccgtttggg
    55441 aactttgggg agcgctgttg tatggcggtc gtttagtaat tgtacccttt tggatcagcc
    55501 gcgaccctca agccttctat cagttgctct gtcaagaaaa agtgacggta cttaaccaaa
    55561 caccctcggc atttcggcaa ctgatttggg tggaggaaca agcagaagta acagtagcca
    55621 aactatatct gcgttgggta atttttggcg gagagagttt agatccatct agcttaatgc
    55681 cttggtttga gcggcatggc gatggtactc cccaactggt gaatatgtac ggcatcactg
    55741 aaaccaccgt tcatgttacc ttccgtcctt tgacaattga ggacgcccac agccggggta
    55801 gtgtaattgg cttaccgata cctgacttgc aactatacat tctcgacgag tcccttcagc
    55861 cagtgcctat tggagtccgg ggacagatgt ttgtcggtgg cgctggggta gcccgtggtt
    55921 atctcaatcg ccctgaatta accgcagatc gctttatcca aaatcccttt agtgagcaac
    55981 taggggataa attatacaaa actggtgatt tagcccgata tcgttcagat ggcaatatcg
    56041 aatacctcgg tcgcatcgat tatcaggtga agattcgcgg cttccgcatt gagttgggag
    56101 aaatcgaagc ggcattgagt caacatcctg ttgtgaagga agctgtggtg attgatcgtg
    56161 agggtaaagc tggtgataag cgtttggtcg cttacattgt ttctgaatcg cagtcagata
    56221 ccctaatggg tgagctgcgt tgctaccttg aggagcagtt gcctgactac atggtaccaa
    56281 gtgcctttgt gctgctggat gttctgcccc taactagcaa tggtaaacta gatcgccgcg
    56341 ctctcccaac tccagatatg ggaaacagcc acggagtaag ctttgtgccg ccacaaacac
    56401 caacagaaga tgcgatcgcg aatattataa cttcagttct agaaattgaa aaaattggta
    56461 tccacgacga cttctttgaa ctcggcggac attctctcct cgctacccaa gtaatatccc
    56521 gcttgcggca aactttctcc gtcgaattgc ccgttcaggt aatttttact actcctacca
    56581 ttgcagaact ggcagaactg gtgattgcta aacaattaga gcaagcagat aatgaggcgc
    56641 tagaactgat tttggctgag gtcaatcagt tatctgaccg cgaagtcaat ttgcaactat
    56701 ctgatcctac caaccacagc agttcttaa
//
