Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001126.1:
Cluster 1Terpene / Alkaloid141745

BGC0001126, ambiguine biosynthetic gene cluster from Fischerella ambigua. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: 3-(Z-2'-isocyanoethenyl)-indole
SMILES string: Copy to clipboard
Molecular formula: C11H8N2
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
Terpene / Alkaloid
Terpene subclass:
Other
Terpene subclass by size:
Monoterpene
Final isoprenoid precursor:
GPP
Terpene synthase/cyclase-encoding genes:
Prenyltransferase-encoding genes:
AHB62774.1, AHB62766.1
Alkaloid subclass:
Indole/benzopyrrole

Gene cluster description

ambiguine (BGC0001126). Gene Cluster 1. Biosynthetic class = Terpene/Alkaloid. GenBank KF664586. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?unknown
Evidence for cluster-compound connection:Enzymatic assays
MIxS-compliance:Unknown
Contact for this cluster:Xinyu Liu (University of Pittsburgh)

Literature references

1. Hillwig ML et al. (2014) Biosynthesis of ambiguine indole alkaloids in cyanobacterium Fischerella ambigua. ACS Chem Biol 9(2):372-7. doi: 10.1021/cb400681n. Epub 2013 Nov 20.