BGC0001127: jagaricin biosynthetic gene cluster from Janthinobacterium agaricidamnosum
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Location: 1 - 45,262 nt. (total: 45,262 nt).
This entry is originally from NCBI GenBank HE967328.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001127
Short description jagaricin biosynthetic gene cluster from Janthinobacterium agaricidamnosum
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: HE967328.2
Compounds
  • jagaricin
Species Janthinobacterium agaricidamnosum [taxonomy]
References
Chemical products information
jagaricin
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C56H84N12O16
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CCM43853.1
 1 - 933 (+) bacterial regulatory, Fis family protein
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  • CCM43854.1
  • mug
 1015 - 1596 (-) G/U mismatch-specific DNA glycosylase
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  • CCM43855.1
 1748 - 2791 (-) SPFH domain / Band 7 family protein
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  • CCJ67643.1
 2778 - 4397 (-) cyclic peptide transporter; siderophore ABC transporter
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  • CCM43856.1
 4437 - 4616 (-) putative membrane protein
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  • CCM43857.1
 5355 - 5876 (+) GTPase domain-containing protein
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  • CCJ67644.1
  • mbtH
 5965 - 6198 (+) MbtH
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  • CCJ67645.1
  • jagA
 6246 - 11117 (+) JagA
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  • CCJ67646.1
  • jagB
 11181 - 19943 (+) JagB
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  • CCJ67647.1
  • jagC
 20030 - 30973 (+) JagC
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  • CCJ67648.1
  • jagD
 30990 - 39770 (+) JagD
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  • CCJ67649.1
  • dctA
 40562 - 41854 (-) C4-dicarboxylate transporter DctA
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  • CCM43858.1
 41922 - 43214 (-) amidase family protein
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  • CCM43859.1
 43525 - 44250 (+) bacterial regulator helix-turn-hlix, LysR family protein
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  • CCM43860.1
 44222 - 45262 (-) bifunvtional NMN adenylyltransferase/Nudix hydrolase
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
jagA
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
  • Homology
jagB
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: tyrosine
Evidence for specificity:
  • Structure-based inference
jagC
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
  • Homology
Module ?
Specificity: glutamine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
jagD
Module ?
Specificity: allo-threonine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: histidine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: 5UL74VURKJ25VSPPPO3H2NYB, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update compound structure (SMILES) for jagaricin
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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