Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001133.1:
Cluster 1NRP165888

BGC0001133, taxlllaid biosynthetic gene cluster from Xenorhabdus bovienii. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: Taxlllaid
SMILES string: Copy to clipboard
Molecular formula: C41H73O9N7
Exact molecular mass: 808.5555 Da ([M+H]+)
Molecular activity: Other

Class-specific details

Biosynthetic class(es):
NRP
Other (cyclic)
Thioesterase type:
Unknown
Release / cyclization type:
Unknown

Nonribosomal peptide synthetases:
XBJ1_0775
Module 1
A specificity: Threonine
Evidence for specificity: Sequence-based prediction
C domain subtype: Unknown
Module 2
A specificity: Serine
Evidence for specificity: Sequence-based prediction
C domain subtype: Unknown
Module 3
A specificity: Tyr,Phe
Evidence for specificity: Structure-based inference
C domain subtype: Unknown
Module 4
A specificity: Leucine
Evidence for specificity: Structure-based inference
C domain subtype: Unknown
XBJ1_0774
Module 5
A specificity: Leucine
Evidence for specificity: Sequence-based prediction
C domain subtype: Unknown
Module 6
A specificity: Leucine
Evidence for specificity: Sequence-based prediction
C domain subtype: Unknown
Module 7
A specificity: Serine
Evidence for specificity: Sequence-based prediction
C domain subtype: Unknown

Gene cluster description

taxlllaid (BGC0001133). Gene Cluster 1. Biosynthetic class = NRP. GenBank FN667741, positions 739318-805205. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Proven expression in natural host, Sequence-based prediction
MIxS-compliance:Unknown
Contact for this cluster:Helge Bode (Goethe Universitat Frankfurt)

Literature references

1. Kronenwerth M et al. (2014) Characterisation of taxlllaids A-G; natural products from Xenorhabdus indica. Chemistry 20(52):17478-87. doi: 10.1002/chem.201403979. Epub 2014