BGC0001136: desmethylbassianin biosynthetic gene cluster from Beauveria bassiana
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Location: 1 - 20,147 nt. (total: 20,147 nt).
This entry is originally from NCBI GenBank HM243222.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
Genes
Polyketide
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001136
Short description desmethylbassianin biosynthetic gene cluster from Beauveria bassiana
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide (Other)
Loci NCBI GenBank: HM243222.1
Compounds
  • desmethylbassianin
Species Beauveria bassiana [taxonomy]
References
Chemical products information
desmethylbassianin
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C22H23N1O5
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADN43681.1
 1 - 88 (-) hypothetical protein
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  • ADN43682.1
 1334 - 2986 (+) P450
  • Tailoring (Oxidation)
Other in vivo study
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  • ADN43683.1
 3394 - 5070 (-) P450
  • Tailoring (Oxidation)
Other in vivo study
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  • ADN43684.1
 5654 - 6823 (-) ER
  • Scaffold biosynthesis
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  • ADN43685.1
 7496 - 20147 (+) PKS-NRPS
  • Scaffold biosynthesis
Other in vivo study
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Polyketide-specific information
Subclass Other
Starter unit Acetyl-CoA
Cyclic? no
Polyketide-synthases
Genes Properties Modules
ADN43685.1 Synthase subclass: Iterative type I
Iterative PKS type: Highly reducing, Unknown
Iteration counts: 5
Module 1
Specificity: Multiple (promiscuous)/Malonyl-CoA/Acetyl-CoA
Genes: ADN43685.1
Core domains: Ketosynthase, Acyltransferase, Dehydratase, Methyltransferase, Enoylreductase, Ketoreductase, Thiolation (ACP/PCP)
KR-domain stereochemistry: Unknown
Non-canonical activity:
  • Iterated
Evidence for non-canonical activity:
  • Structure-based inference
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
ADN43685.1
Module 2 [inactive]
Specificity: tyrosine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Unknown
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: 3XTF2R3BHL5LPPSMGJ2QHJQC, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: 5UL74VURKJ25VSPPPO3H2NYB, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Linked new PubChem id for desmethylbassianin (pubchem:91820224)
  • Corrected NRP module activity
  • Corrected gene identifiers
  • Changed amino acid substrates to lower case
Detailed domain annotation
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