BGC0001140 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001140 (Streptomyces platensis)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	terpene	1	41,208	High	platensimycin/platencin/thioplatensimycin/thioplatencin/platensilin/thioplatensilin	terpene:Diterpene

BGC0001140 - Region 1 - terpene

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Location: 1 - 41,208 nt. (total: 41,208 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Terpene

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 41,209
Label		BGC0001140

Tailoring functions

Oxidoreductases: dehydrogenase oxygenase

ACO31265.1: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

ACO31275.1: cytochrome P450

smcogs: SMCOG1034: cytochrome P450

ACO31277.1: dioxygenase, TauD/TfdA

smcogs: SMCOG1121: dioxygenase, TauD/TfdA

ACO31278.1: acyl-CoA dehydrogenase

smcogs: SMCOG1006: acyl-CoA dehydrogenase

ACO31280.1: cytochrome P450

smcogs: SMCOG1007: cytochrome P450

ACO31282.1: dioxygenase, TauD/TfdA

smcogs: SMCOG1121: dioxygenase, TauD/TfdA

ACO31293.1: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

ACO31295.1: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: acetyltransferase

ACO31292.1: acetyl-CoA acetyltransferase

smcogs: SMCOG1124: acetyl-CoA acetyltransferase

Lyases: dehydratase

ACO31296.1: L-carnitine dehydratase/bile acid-inducible

smcogs: SMCOG1189: L-carnitine dehydratase/bile acid-inducible

Ligases: ligase synthase synthetase

ACO31271.1: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

ACO31283.1: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

ACO31286.1: 1-deoxy-D-xylulose-5-phosphate synthase

smcogs: SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase

ACO31291.1: hydroxymethylglutaryl-CoA synthase

smcogs: SMCOG1043: hydroxymethylglutaryl-CoA synthase

ACO31297.1: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

ACS13710.1: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001140.5	0.78	terpene	platensimycin, platencin, thioplatensimycin, thioplatencin, platensilin, thioplatensilin	Streptomyces platensis
BGC0001156.5	0.68	terpene	platencin	Streptomyces platensis
BGC0000677.5	0.55	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0001911.3	0.54	terpene	raimonol	Streptomyces anulatus
BGC0002631.2	0.54	ribosomal	Myxarylin	Pyxidicoccus fallax
BGC0001361.3	0.54	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002283.2	0.54	terpene	sodorifen	Serratia plymuthica
BGC0002043.3	0.53	ribosomal	cittilin A, cittilin B	Myxococcus xanthus DK 1622
BGC0002591.2	0.53	PKS, terpene	aurachin C, aurachin D, aurachin SS	Streptomyces sp.
BGC0001528.4	0.51	terpene	betaestacin I, betaestacin II	Phoma betae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001140.5	0.92	terpene	platensimycin, platencin, thioplatensimycin, thioplatencin, platensilin, thioplatensilin	Streptomyces platensis
BGC0001156.5	0.88	terpene	platencin	Streptomyces platensis
BGC0002276.2	0.58	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0000671.3	0.56	terpene	momilactone B	Oryza sativa Japonica Group
BGC0002274.2	0.56	NRPS	aspulvinone H, aspulvinone B1	Aspergillus terreus NIH2624
BGC0001911.3	0.55	terpene	raimonol	Streptomyces anulatus
BGC0000677.5	0.55	terpene	cyclooctatin	Streptomyces melanosporofaciens
BGC0002631.2	0.54	ribosomal	Myxarylin	Pyxidicoccus fallax
BGC0001361.3	0.54	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002283.2	0.54	terpene	sodorifen	Serratia plymuthica

Similar known clusters from MIBiG 4.0

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
diterpene			C20	C6-C11 + C10-C15	PP

Genes with terpene domains:

ACO31276.1: T2TS

Domain 1 (8 - 521): Type 2 terpene synthase

Subtype: Diterpene synthase

Reactions:: GGPP → diterpene_C6-C11/C10-C15_PP

ACO31279.1: T1TS

Domain 1 (21 - 280): Type 1 terpene synthase

Subtype: unknown

ACO31283.1: PT_FPPS_like

Domain 1 (60 - 344): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

Terpene

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate