BGC0001140: platensimycin biosynthetic gene cluster from Streptomyces platensis
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Location: 4,531 - 45,738 nt. (total: 41,208 nt).
This entry is originally from NCBI GenBank FJ655920.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Terpene
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001140
Short description platensimycin biosynthetic gene cluster from Streptomyces platensis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Terpene (Diterpene/Unknown)
Loci NCBI GenBank: FJ655920.1
Compounds
  • platensimycin
  • platencin
  • thioplatensimycin
  • thioplatencin
Species Streptomyces platensis [taxonomy]
References
Chemical products information
platensimycin
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C24H27N1O7
Chemical database entries
NPAtlas
PubCHEM
platencin
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C24H27N1O6
Chemical database entries
NPAtlas
PubCHEM
thioplatensimycin
(no structure information available)
thioplatencin
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACO31265.1
 4628 - 5392 (-) Ptm01
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  • ACO31266.1
 5389 - 5943 (-) PtmU1
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  • ACO31267.1
 6030 - 7334 (+) PtmA1
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  • ACO31268.1
 7331 - 8041 (+) PtmU2
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  • ACO31269.1
 8087 - 8488 (-) PtmR2
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  • ACO31270.1
 8488 - 9645 (-) PtmD
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  • ACO31271.1
 9647 - 11215 (-) PtmA2
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  • ACO31272.1
 11244 - 12326 (-) PtmU3
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  • ACO31273.1
 12408 - 13262 (-) PtmH
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  • ACO31274.1
 13327 - 14253 (-) PtmT1
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  • ACO31275.1
 14250 - 15572 (-) PtmO2
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  • ACO31276.1
 15572 - 17173 (-) PtmT2
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  • ACO31277.1
 17311 - 18168 (+) PtmO3
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  • ACO31278.1
 18168 - 19334 (+) PtmO4
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  • ACO31279.1
 19331 - 20260 (+) PtmT3
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  • ACO31280.1
 20301 - 21593 (+) PtmO5
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  • ACO31281.1
 21590 - 22657 (+) PtmR3
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  • ACO31282.1
 22745 - 23587 (+) PtmO6
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  • ACO31283.1
 23644 - 24690 (+) GGDP synthase
  • Precursor biosynthesis
Sequence-based prediction
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  • ACO31284.1
 24690 - 26036 (+) HMBDP reductase
  • Precursor biosynthesis
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  • ACO31285.1
 26044 - 27144 (+) HMBDP synthase
  • Precursor biosynthesis
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  • ACO31286.1
 27131 - 28894 (+) DXP synthase
  • Precursor biosynthesis
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  • ACO31287.1
 28972 - 29805 (+) ADHOHP synthase
  • Precursor biosynthesis
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  • ACO31288.1
 29857 - 30963 (+) ADHOHP synthase
  • Precursor biosynthesis
Sequence-based prediction
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  • ACO31289.1
 30969 - 32159 (+) PtmB3
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  • ACO31290.1
 32218 - 33093 (+) PtmC
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  • ACO31291.1
 33179 - 34603 (-) PtmP1
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  • ACO31292.1
 34675 - 35919 (+) PtmP2
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  • ACO31293.1
 35934 - 36839 (+) PtmO7
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  • ACO31294.1
 36872 - 37588 (-) PtmR1
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  • ACO31295.1
 37880 - 38716 (+) PtmO8
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  • ACO31296.1
 38713 - 40503 (+) PtmU4
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  • ACO31297.1
 40542 - 42125 (+) PtmA3
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  • ACS13710.1
 42293 - 43507 (+) Resistance gene
  • Resistance/immunity
Activity assay
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  • ACS13711.1
 43625 - 45247 (+) PtmP4
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  • ACS13712.1
 45271 - 45606 (+) PtmO9
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Terpene-specific information
Carbon count subclass Diterpene
Structural subclass Unknown
Isoprenoid precursor GGPP
Prenyltransferases ACO31283.1
Terpene synthases/cyclases ACO31274.1, ACO31276.1, ACO31279.1
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: QARZXBIU2LN42R2C3IX7JEGD, no GDPR consent given).
  • Hidden contributor (ID: E2T2HCM4X7QXVS4LL4JVBPPK, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Hidden contributor (ID: 3UOU7PODQJXIM6BEPUHHRRA5, no GDPR consent given).
  • Merged annotations from duplicate entry BGC0001898
  • Fixed gene accessions
  • Added AMP-binding domain substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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