BGC0001141: 4-epi-15-epi-brefeldin A biosynthetic gene cluster from Penicillium brefeldianum
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Location: 1 - 37,663 nt. (total: 37,663 nt).
This entry is originally from NCBI GenBank KJ728786.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001141
Short description 4-epi-15-epi-brefeldin A biosynthetic gene cluster from Penicillium brefeldianum
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Iterative type I)
Loci
KJ728786.1
via Knock-out studies
Compounds
  • 4-epi-15-epi-brefeldin A
Species Penicillium brefeldianum [taxonomy]
References
Chemical products information
4-epi-15-epi-brefeldin A Evidence:
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C16H24O4
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AIA58894.1
 263 - 2905 (+) putative F-box domain protein
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    • AIA58903.1
    		 3699 - 4681 (-) thiohydrolase
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      • AIA58895.1
      		 5541 - 7257 (+) putative cytochrome P450
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        • AIA58896.1
        		 7855 - 9494 (+) putative cytochrome P450
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          • AIA58897.1
          		 10514 - 12193 (+) putative cytochrome P450
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            • AIA58898.1
            		 12965 - 14473 (-) putative cytochrome P450
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              • AIA58899.1
              		 16191 - 23507 (+) HRPKS
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                • AIA58900.1
                		 24185 - 25201 (-) putative large tegument protein UL36
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                  • AIA58901.1
                  		 29688 - 34538 (-) putative WD-40 protein
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                    • AIA58902.1
                    		 36036 - 37660 (+) putative kinesin
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                      Biosynthesis information

                      Biosynthetic modules

                      Name
                      1
                      Type
                      pks-modular
                      Genes
                      AIA58899.1
                      Substrates
                      Integrated Monomers
                      Domains
                      acyltransferase, ketosynthase, acyltransferase, dehydratase, enoylreductase, ketoreductase, carrier (ACP)
                      Annotation changelog

                      Entry version: next

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2024-08-01
                      MIBiG v4 annotathon
                      • (ID: JXNPUXPAL6VYCS4XEXVRJDGK)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 3

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-09-15
                      Corrected gene identifiers
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 2

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2019-10-16
                      Migrated from v1.4
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      2019-10-16
                      Updated compound(s) information (NPAtlas curation)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 1

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2015-06-12
                      Submitted
                      • (ID: BMUFDHMMOLZWQLUNJMQED2GP)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      Detailed domain annotation
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