BGC0001142: tryptoquialanine biosynthetic gene cluster from Penicillium aethiopicum
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Location: 1 - 59,698 nt. (total: 59,698 nt).
This entry is originally from NCBI GenBank HQ591508.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001142
Short description tryptoquialanine biosynthetic gene cluster from Penicillium aethiopicum
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: HQ591508.1
Compounds
  • tryptoquialanine
Species Penicillium aethiopicum [taxonomy]
References
Chemical products information
tryptoquialanine
Copy SMILES
C27H26N4O7
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADY16684.1
 283 - 1607 (-) hypothetical protein
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  • ADY16685.1
 3395 - 5346 (+) hypothetical protein
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  • ADY16686.1
 6261 - 8022 (+) hypothetical protein
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  • ADY16687.1
 8692 - 9797 (-) TqaC
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  • ADY16688.1
 10237 - 11778 (+) TqaD
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  • ADY16689.1
 12833 - 16159 (+) TqaB
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  • ADY16690.1
 16443 - 18062 (-) TqaE
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  • ADY16691.1
 18577 - 19633 (+) TqaM
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  • ADY16692.1
 19715 - 20431 (-) TqaF
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  • ADY16693.1
 21261 - 22758 (+) TqaK
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  • ADY16694.1
 23331 - 24446 (+) TqaL
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  • ADY16695.1
 25510 - 27232 (-) TqaG
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  • ADY16696.1
 28030 - 29574 (-) TqaH
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  • ADY16697.1
 30584 - 42893 (+) TqaA
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  • ADY16698.1
 43810 - 44619 (+) TqaI
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  • ADY16699.1
 45638 - 47489 (-) TqaJ
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  • ADY16700.1
 48947 - 50248 (-) hypothetical protein
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  • ADY16701.1
 52301 - 53119 (-) putative RTA1-like transmembrane protein
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  • ADY16702.1
 53873 - 55259 (+) putative Zn2Cys6 transcription factor
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  • ADY16703.1
 55454 - 57406 (-) hypothetical protein
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  • ADY16704.1
 57831 - 58406 (+) hypothetical protein
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  • ADY16705.1
 58720 - 59343 (+) hypothetical protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
ADY16689.1
Module ?
Specificity: 2-aminoisobutyric acid / D-alanine / alanine / D-2-aminobutyric acid
Evidence for specificity:
  • Structure-based inference
  • ATP-PPi exchange assay
ADY16697.1
Module ?
Specificity: anthanillic acid
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: tryptophan
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: alanine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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