BGC0001145: cyclothiazomycin b1 biosynthetic gene cluster from Streptomyces mobaraensis NBRC 13819 = DSM 40847
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 35,019 - 50,744 nt. (total: 15,726 nt).
This entry is originally from NCBI GenBank AORZ01000028.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001145
Short description cyclothiazomycin b1 biosynthetic gene cluster from Streptomyces mobaraensis NBRC 13819 = DSM 40847
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP (Thiopeptide)
Loci NCBI GenBank: AORZ01000028.1
Compounds
  • cyclothiazomycin b1
Species Streptomyces mobaraensis NBRC 13819 = DSM 40847 [taxonomy]
References
Chemical products information
cyclothiazomycin b1
Copy SMILES
C61H69N21O13S7
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • H340_11735
  • EMF00378.1
35019 - 36929 (+) hypothetical protein
copy AA seq
copy Nt seq
  • H340_11740
  • EMF00379.1
36922 - 38853 (+) NADH oxidase
copy AA seq
copy Nt seq
  • H340_11745
  • EMF00380.1
39013 - 39195 (+) hypothetical protein
copy AA seq
copy Nt seq
  • H340_11750
  • EMF00381.1
39323 - 41266 (+) hypothetical protein
copy AA seq
copy Nt seq
  • H340_11755
  • EMF00382.1
41282 - 43879 (+) Lanthionine biosynthesis protein
copy AA seq
copy Nt seq
  • H340_11760
  • EMF00383.1
43866 - 44885 (+) Lantibiotic biosynthesis protein
copy AA seq
copy Nt seq
  • H340_11765
  • EMF00384.1
44882 - 46075 (+) hypothetical protein
copy AA seq
copy Nt seq
  • H340_11770
  • EMF00385.1
46250 - 47059 (+) hypothetical protein
copy AA seq
copy Nt seq
  • H340_11775
  • EMF00386.1
47080 - 47625 (-) hypothetical protein
copy AA seq
copy Nt seq
  • H340_11780
  • EMF00387.1
47937 - 50744 (-) LuxR family transcriptional regulator
copy AA seq
copy Nt seq
RiPP-specific information
Subclass Thiopeptide
Cyclic? yes
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: FTVL3IN3CWSJUJDTYVJJVU23, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Changed to GenBank accession to match gene annotations
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.