BGC0001145: cyclothiazomycin b1 biosynthetic gene cluster from Streptomyces mobaraensis NBRC 13819 = DSM 40847
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Location: 35,019 - 50,744 nt. (total: 15,726 nt).
This entry is originally from NCBI GenBank AORZ01000028.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001145
Short description cyclothiazomycin b1 biosynthetic gene cluster from Streptomyces mobaraensis NBRC 13819 = DSM 40847
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • ribosomal (RiPP)
Loci
AORZ01000028.1
35019 - 50744
via
Compounds
  • cyclothiazomycin b1
Species Streptomyces mobaraensis NBRC 13819 = DSM 40847 [taxonomy]
References
Chemical products information
cyclothiazomycin b1 Evidence:
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C61H69N21O13S7
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • H340_11735
  • EMF00378.1
 35019 - 36929 (+) hypothetical protein
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    • H340_11740
    • EMF00379.1
    		 36922 - 38853 (+) NADH oxidase
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      • H340_11745
      • EMF00380.1
      		 39013 - 39195 (+) hypothetical protein
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        • H340_11750
        • EMF00381.1
        		 39323 - 41266 (+) hypothetical protein
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          • H340_11755
          • EMF00382.1
          		 41282 - 43879 (+) Lanthionine biosynthesis protein
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            • H340_11760
            • EMF00383.1
            		 43866 - 44885 (+) Lantibiotic biosynthesis protein
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              • H340_11765
              • EMF00384.1
              		 44882 - 46075 (+) hypothetical protein
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                • H340_11770
                • EMF00385.1
                		 46250 - 47059 (+) hypothetical protein
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                  • H340_11775
                  • EMF00386.1
                  		 47080 - 47625 (-) hypothetical protein
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                    • H340_11780
                    • EMF00387.1
                    		 47937 - 50744 (-) LuxR family transcriptional regulator
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                      Biosynthesis information
                      Annotation changelog

                      Entry version: 4

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-10-07
                      Update chemical activity to schema version 2.11
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 3

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2022-09-15
                      Changed to GenBank accession to match gene annotations
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      2022-09-15
                      Updated bioactivity data
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 2

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2019-10-16
                      Migrated from v1.4
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      2019-10-16
                      Updated compound(s) information (NPAtlas curation)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 1

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2015-06-12
                      Submitted
                      • (ID: FTVL3IN3CWSJUJDTYVJJVU23)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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