BGC0001147 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001147 (Streptomyces netropsis)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	28,600	disgocidine/distamycin/congocidine	NRPS:Type I	100%

BGC0001147 - Region 1 - NRPS

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Location: 1 - 28,600 nt. (total: 28,600 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 28,601
Label		BGC0001147

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001147	0.93	NRP	disgocidine, distamycin, congocidine	Streptomyces netropsis
BGC0000375	0.34	NRP	indigoidine	Streptomyces chromofuscus
BGC0000772	0.33	Saccharide	lipopolysaccharide	Brucella melitensis
BGC0000900	0.31	Other	ferrichrome	Aspergillus oryzae
BGC0002710	0.29	NRP	metachelin C, metachelin A, metachelin A-CE, metachelin B, dimerumic acid 11-mannoside, dimerumic acid	Metarhizium robertsii ARSEF 23
BGC0000727	0.29	Saccharide	indigoidine	Streptomyces aureofaciens
BGC0000348	0.29	NRP	ergovaline	Epichloe festucae var. lolii
BGC0001561	0.28	NRP	curacomycin	Streptomyces curacoi
BGC0000876	0.28	Other	neopolyoxin C	Streptomyces tendae
BGC0001817	0.28	Other	vancosamine	Streptomyces sp. WAC2288

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001147	1.00	NRP	disgocidine, distamycin, congocidine	Streptomyces netropsis
BGC0000375	0.67	NRP	indigoidine	Streptomyces chromofuscus
BGC0000772	0.66	Saccharide	lipopolysaccharide	Brucella melitensis
BGC0000900	0.65	Other	ferrichrome	Aspergillus oryzae
BGC0001561	0.64	NRP	curacomycin	Streptomyces curacoi
BGC0000727	0.63	Saccharide	indigoidine	Streptomyces aureofaciens
BGC0001225	0.63	NRP	celesticetin	Streptomyces caelestis
BGC0000348	0.62	NRP	ergovaline	Epichloe festucae var. lolii
BGC0002652	0.62	Other, Saccharide	cytosaminomycin F, cytosaminomycin G, streptcytosine P, plicacetin, 40551-F, 12F-plicacetin, streptcytosine D, streptcytosine E	Streptomyces sp. SHP22-7
BGC0000876	0.62	Other	neopolyoxin C	Streptomyces tendae

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 2667 - 28600:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

dst22

AMP-binding (16..413): X

nrpys: Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: -GAVLSVIIK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

dst18

AMP-binding (25..436): X

nrpys: Gua

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: SVEQVGEVSK
Nearest Stachelhaus code(s):: Gua SVEQVGEVSK (100% 8Å match)
Stachelhaus code match:: 100% (strong)