BGC0001147: disgocidine biosynthetic gene cluster from Streptomyces netropsis
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Location: 1 - 28,600 nt. (total: 28,600 nt).
This entry is originally from NCBI GenBank KJ634466.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001147
Short description disgocidine biosynthetic gene cluster from Streptomyces netropsis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: incomplete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Remarks "Contig lacks AIS24865.1, AIS24866.1, AIS24867.1 as part of the NRPS"
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: KJ634466.1
Compounds
  • disgocidine
  • distamycin
  • congocidine
Species Streptomyces netropsis [taxonomy]
References
Chemical products information
disgocidine
(no structure information available)
Chemical database entries
ChemSpider
distamycin
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C22H27N9O4
Chemical database entries
PubCHEM
ChemSpider
congocidine [synonyms: netropsin, sinanomycin]
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C18H26N10O3
Chemical database entries
PubCHEM
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AIS24844.1
  • dst22
 99 - 1670 (-) dst22
  • Scaffold biosynthesis
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  • AIS24845.1
  • dst21
 1654 - 3558 (-) dst21
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  • AIS24846.1
  • dst20
 3558 - 5408 (-) dst20
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  • AIS24847.1
  • dst1
 5983 - 6657 (+) dst1
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  • AIS24848.1
  • dst2
 6990 - 8387 (+) dst2
  • Scaffold biosynthesis
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  • AIS24849.1
  • dst4
 8737 - 9282 (+) dst4
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  • AIS24850.1
  • dst5
 9279 - 10196 (+) dst5
  • Precursor biosynthesis
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  • AIS24851.1
  • dst6
 10193 - 10990 (+) dst6
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  • AIS24852.1
  • dst7
 11043 - 12176 (+) dst7
  • Precursor biosynthesis
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  • AIS24853.1
  • dst8
 12227 - 13531 (+) dst8
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  • AIS24854.1
  • dst9
 13524 - 14504 (+) dst9
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  • AIS24855.1
  • dst10
 14510 - 15583 (+) dst10
  • Precursor biosynthesis
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  • AIS24856.1
  • dst11
 15589 - 16344 (+) dst11
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  • AIS24857.1
  • dst12
 16341 - 17492 (+) dst12
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  • AIS24858.1
  • dst13
 17474 - 19390 (+) dst13
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  • AIS24859.1
  • dst15
 19442 - 20215 (+) dst15
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  • AIS24860.1
  • dst16
 20219 - 21628 (+) dst16
  • Scaffold biosynthesis
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  • AIS24861.1
  • dst17
 21625 - 22671 (+) dst17
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  • AIS24862.1
  • dst18
 22668 - 25859 (+) dst18
  • Scaffold biosynthesis
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  • AIS24863.1
 25936 - 27363 (-) Dst3
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  • AIS24864.1
  • dst19
 27747 - 28109 (+) dst19
  • Scaffold biosynthesis
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
dst22
Module ? [inactive]
Specificity: 4-acetamidopyrrole-2-carboxylic acid
Evidence for specificity:
dst2
Module ? [inactive]
Condensation domain type: Unknown
dst16
Module ? [inactive]
Condensation domain type: LCL
dst18
Module ? [inactive]
Specificity: glycocyamine
Evidence for specificity:
Condensation domain type: LCL
dst19
Module ? [inactive]
Annotation changelog
MIBiG version Submitter Notes
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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