LOCUS       BGC0001150             23437 bp    DNA     linear   BCT 11-MAR-2015
DEFINITION  Streptomyces alboniger strain DSM 40043 TetR family transcription
            regulator (pamR2), drug resistance transporter, EmrB/QacA family
            (pamW), acyl-carrier protein (pamC), Ketoacyl-acyl carrier protein
            synthase III (pamG), Ketoacyl-acyl carrier protein synthase II
            (pamF), Ketoacyl-acyl carrier protein synthase II (pamA), 3-ketoacid
            (adipate/glutaconate) CoA transferase (pamB), Ketoacyl-acyl carrier
            protein synthase III (pamD), Ketoacyl-acyl carrier protein synthase
            III (pamE), Ketoacyl-(acyl-carrier-protein) reductase (pamO),
            Ketoacyl-acyl carrier protein synthase III (pamK), Ketoacyl-acyl
            carrier protein synthase II (pamJ), Ketoacyl-(acyl-carrier-protein)
            reductase (pamM), Ketoacyl-(acyl-carrier-protein) reductase (pamN),
            Hydroxyl acids CoA ligase (pamL), Metal-dependent hydrolase
            (resistance) (pamH), Aminotransferase (pamX), Methyltransferase
            (pamY), Enoyl-CoA hydratase (pamS), and Response regulator LuxR
            family (pamR1) genes, complete cds.
ACCESSION   BGC0001150
VERSION     BGC0001150
KEYWORDS    .
SOURCE      Streptomyces alboniger
  ORGANISM  Streptomyces alboniger
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces aurantiacus group.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 15:00:19
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 23437
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..23437
                     /culture_collection="DSM:40043"
                     /db_xref="taxon:132473"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces alboniger"
                     /strain="DSM 40043"
                     /type_material="type strain of Streptomyces alboniger"
     subregion       1..23437
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001150"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..23437
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(13..750)
                     /gene="pamR2"
                     /locus_tag="SALB_00464"
     CDS             complement(13..750)
                     /codon_start=1
                     /gene="pamR2"
                     /gene_functions="regulatory (smcogs) SMCOG1239:TetR family
                     transcriptional regulator (Score: 187.2; E-value: 6.1e-57)"
                     /gene_kind="regulatory"
                     /locus_tag="SALB_00464"
                     /product="TetR family transcription regulator"
                     /protein_id="AJS09379.1"
                     /transl_table=11
                     /translation="MNETSGRENTPKGQPGSIWLREVKQRPARQPLSREQIVQAAVRLL
                     DEGGVRNLRMRQLADSLNSAPMSLYWHVSTKDDLLELAIDAVFPDPPSRSGTGDWRDDI
                     KAGATDLFEVLLRHSWMIELMGGHPPVGPRALAHTSAIIEILEQAHFSPRQLDSALSAI
                     YYYTVGAALSEASWQAMARQSAESEEEWVSRLGPYLGMATQSHPASLADYVKRSASSST
                     GQRFHDGLECMVSGMGQMRSQDS"
     misc_feature    13..23077
                     /note="pamamycin genen cluster"
     gene            838..2514
                     /gene="pamW"
                     /locus_tag="SALB_00465"
     CDS             838..2514
                     /codon_start=1
                     /gene="pamW"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 360; E-value:
                     2.4e-109)"
                     /gene_kind="transport"
                     /locus_tag="SALB_00465"
                     /product="drug resistance transporter, EmrB/QacA family"
                     /protein_id="AJS09380.1"
                     /transl_table=11
                     /translation="MDGVVHEQQGAGRGGGEGGDDGGVPGAKNRWAVLGVLSLSLLVVA
                     LDLTVLNVALPTLSTELRPSSVQLLWIVDVYSLVVAGLLISCGTLGDRLGRKRFLCLGF
                     IVFGGASAAAAWASGPAMLITARALLGIGAAIIMPSTLSIIRNVFTDRKERTVALAVWA
                     TMSAAGAAVGPVVGGVMIEHFWWGSVFLINVPIMVLALIAALTLVPESRHPNPPRWDTA
                     GALLSVTGLISLVYAIQHGGAKGLEAQTIITGVLGLVLLTALVVRVLRIRDPLFDPTLF
                     RDRAFSVAVVSVVLAMFGMGGLMLLLTQHWQFIGGASPMESGLQLLPLLLATMIGAPIM
                     SVIVPRYGTRYAMMIGMGLIGAAFFVLMNVEPDTEYWVFAIALAGIGAGAGCAMTAASD
                     AIMSTADADTAGGAAGIEETSYELGNGLSVAIMGSVASALFRREMDDPVAGVDPKAMDA
                     AREGLPDAVGVAGALPGAVGEELKRRADNAFTDAFGVTSLCTGVILVVVAVAVFLFIPP
                     SAGRITPATEGGGDAPEDGVDLVKQESRESADGRPTPVDRP"
     gene            complement(2611..2841)
                     /gene="pamC"
                     /locus_tag="SALB_00466"
     CDS             complement(2611..2841)
                     /NRPS_PKS="Domain: PP-binding (6-69). E-value: 7.1e-16.
                     Score: 50.4. Matches aSDomain:
                     nrpspksdomains_SALB_00466_PP-binding.1"
                     /codon_start=1
                     /gene="pamC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00466"
                     /product="acyl-carrier protein"
                     /protein_id="AJS09381.1"
                     /sec_met_domain="PP-binding (E-value: 2.5e-16, bitscore:
                     50.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYESVKSLLTNEFKISEDRIAPDSTLEDLGLDSLASVEFALALEK
                     GFGVEITDDEVVELERLDRIVELVERRKQAS"
     aSDomain        complement(2635..2823)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SALB_00466_PP-binding.1"
                     /evalue="7.10E-16"
                     /label="SALB_00466_PP-binding.1"
                     /locus_tag="SALB_00466"
                     /protein_end="69"
                     /protein_start="6"
                     /score="50.4"
                     /tool="antismash"
                     /translation="SLLTNEFKISEDRIAPDSTLEDLGLDSLASVEFALALEKGFGVEI
                     TDDEVVELERLDRIVELV"
     gene            complement(2895..3929)
                     /gene="pamG"
                     /locus_tag="SALB_00467"
     CDS             complement(2895..3929)
                     /codon_start=1
                     /gene="pamG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 360.1; E-value: 1.6e-109)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00467"
                     /product="Ketoacyl-acyl carrier protein synthase III"
                     /protein_id="AJS09382.1"
                     /sec_met_domain="fabH (E-value: 4.2e-110, bitscore: 358.2,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHNRTRAAVLAGVAGWVPPGTVTNADLEARLDTTDDWIRSRTGI
                     AERHTVPPGMATRELAVEAGRLALKSAGRDDVDAVVLATATPDRLCPATAPEVAAALGL
                     GPVAAHDVAAVCAGFLYALSAGVGAIAAGFADRVLVIGAETFSAIVDPQDRNTAVIFGD
                     AAGAVVLRAGDPDEPGAIGPIRLGSDGTHSDLIQIPAGGARQRAARTVPEPSDHHLQMQ
                     GRKVYRHAKERMAQSAREVIERSGWTVEDVDRLATHQANARISEAVADELGVPRDRVLS
                     NIEHVGNTSAASLPLLLADSAAAGRLRTNDRVLLAAFGGGLAWGAASLTWPDVTALAVH
                     TYRG"
     gene            complement(3941..5260)
                     /gene="pamF"
                     /locus_tag="SALB_00468"
     CDS             complement(3941..5260)
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (54-400). E-value:
                     5.7e-14. Score: 43.6. Matches aSDomain:
                     nrpspksdomains_SALB_00468_PKS_KS.1"
                     /codon_start=1
                     /gene="pamF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2ks"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 157.1; E-value:
                     1.2e-47)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00468"
                     /product="Ketoacyl-acyl carrier protein synthase II"
                     /protein_id="AJS09383.1"
                     /sec_met_domain="t2ks (E-value: 6.1e-37, bitscore: 117.9,
                     seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHQQQDPGRDALITGMGFALPGPGGLCATSAQFLDIVSTGACYV
                     ENDGVFFGQVRTDIADVKERYPELPVKALKLYSPVQLLGLISMAEACGDAGLDWRSGAL
                     SQAAILAARDGGDCWSAQYADILNTDRTQATKDEINELGTRLALTGIPMDVANVQVSVV
                     AGTGPNFTVSNGCTSSAVLLGMAGRMIADGEVEVAVVTGADVFGLGFLRHYADLLDRYA
                     ELSAEEGITVDAMEDAALAMGAQMRPYDKNSPGSNMGNGSITLVVESRAHAERRGATPY
                     SRMLAQRTRRSPQHSAFAIDRAGTGMVQASRDAMAGLVEAEQIDYVNGGAEGDRVFHET
                     ESNIMRSLFGDRATAMPVTVQEACFGHNGGPLGALGVAATSLMIQRDLVFPTAGCVDPD
                     DTCLFDPVPGTTARPLRIDHALSFNYTVGMVSSAILLGKA"
     aSDomain        complement(4061..5098)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SALB_00468_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="5.70E-14"
                     /label="SALB_00468_PKS_KS.1"
                     /locus_tag="SALB_00468"
                     /protein_end="400"
                     /protein_start="54"
                     /score="43.6"
                     /tool="antismash"
                     /translation="VRTDIADVKERYPELPVKALKLYSPVQLLGLISMAEACGDAGLDW
                     RSGALSQAAILAARDGGDCWSAQYADILNTDRTQATKDEINELGTRLALTGIPMDVANV
                     QVSVVAGTGPNFTVSNGCTSSAVLLGMAGRMIADGEVEVAVVTGADVFGLGFLRHYADL
                     LDRYAELSAEEGITVDAMEDAALAMGAQMRPYDKNSPGSNMGNGSITLVVESRAHAERR
                     GATPYSRMLAQRTRRSPQHSAFAIDRAGTGMVQASRDAMAGLVEAEQIDYVNGGAEGDR
                     VFHETESNIMRSLFGDRATAMPVTVQEACFGHNGGPLGALGVAATSLMIQRDLVFPTAG
                     CVDPDD"
     gene            5472..6809
                     /gene="pamA"
                     /locus_tag="SALB_00469"
     CDS             5472..6809
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (178-415). E-value:
                     2.6e-28. Score: 90.9. Matches aSDomain:
                     nrpspksdomains_SALB_00469_PKS_KS.1"
                     /codon_start=1
                     /gene="pamA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 250.8; E-value:
                     4.1e-76)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00469"
                     /product="Ketoacyl-acyl carrier protein synthase II"
                     /protein_id="AJS09384.1"
                     /sec_met_domain="t2fas (E-value: 4.2e-71, bitscore: 230.2,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAQAESAARKNRGDSVLVTGIGVMLPGATHVNEFWQDVRDGNSR
                     LGRLTRCVPGRTGVRVAGELRDFDHRKFLPELNEKFAGRYTRDALVTMSAVEEARRDAG
                     LGSGEIDPLRLSLIASSSRGPLEWVSQALREDDSVGNREGHEDHEAGSTAHFGDSGAML
                     RGMPGAPATLSAIYGDVRGLVTTLSSACVGGHHAIGFAADLIRAGTADAVVVVGYEFPL
                     TPLVFQSFQAMGDRVLSAESADPRRAIRPYTRDREGFAFGEGAVALCLERESHARARGA
                     GGYARFLSHRALNEATHPFGMDMSGQITASAVAGALQDAGRTPRDVDWFCAHGTATPKN
                     DVAESRMLGALYEGRPRSAWPPLSSVKPVYGHLLGAAALVNAAATSLALHHQCLCSTAN
                     YADAVPDPECDHDHVAEGARATRTELAVSLAFAIGSQTSVLALGAA"
     aSDomain        6006..6716
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SALB_00469_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.60E-28"
                     /label="SALB_00469_PKS_KS.1"
                     /locus_tag="SALB_00469"
                     /protein_end="415"
                     /protein_start="178"
                     /score="90.9"
                     /tool="antismash"
                     /translation="DVRGLVTTLSSACVGGHHAIGFAADLIRAGTADAVVVVGYEFPLT
                     PLVFQSFQAMGDRVLSAESADPRRAIRPYTRDREGFAFGEGAVALCLERESHARARGAG
                     GYARFLSHRALNEATHPFGMDMSGQITASAVAGALQDAGRTPRDVDWFCAHGTATPKND
                     VAESRMLGALYEGRPRSAWPPLSSVKPVYGHLLGAAALVNAAATSLALHHQCLCSTANY
                     ADAVPDPECDHDHVA"
     gene            6806..8668
                     /gene="pamB"
                     /locus_tag="SALB_00470"
     CDS             6806..8668
                     /codon_start=1
                     /gene="pamB"
                     /locus_tag="SALB_00470"
                     /product="3-ketoacid (adipate/glutaconate) CoA transferase"
                     /protein_id="AJS09385.1"
                     /transl_table=11
                     /translation="MTGAEPARTEPLKETMSTHSGTAPRPDIVPDVVPDVDSLVSRYVT
                     PGMHLHLAMTMARPNAMVYALARRFAGRGEFTVSTSATHTAMHALTMSGAVRHLITCFL
                     GDTYPTPRPNPLYRDLARGIPFTCELWSLLSFTQRLMAGATGLPYAVTSSLIGSDLERG
                     LTGDGPGTRPLPEGEQPLGGPKFLRLPGRSAEERPFGLVERLRPDLTLVHGACADRRGN
                     IVLVPPAGEGAWAAYAAEQGVLASVERIVPDDFTDGHPERIVIPGRRVLALCEAPLGAH
                     PQSLRGLATGDERGDVSGYRDDYAFLTELVDRLATEDGAKEWYREWVEEPAGHAQYVRK
                     LGEARRAELTLASGPLTSREPATPPVPLPAGAIAAEPVTRQERTIVLGARAIADRVTRD
                     GYDTLLAGIGVSHLAAWLAAALLREQGVRVPVCAELGFYGMDPEPGDVFLFSQLHATRS
                     QQLVGIPEILGGMVSANPRCLGVLAAGEVDADGNVNTSLLADGRWLTGSGGANDIATST
                     DCLVLSTASPRKFVERVAYVTSPGARVREVVSHFGRFRREQDTRGAFRLATWLPLNDGP
                     ASPEEAVAALTRWPVSGAGCTAEPQVTEAEIAWLRSLDPQGFYR"
     gene            8706..9665
                     /gene="pamD"
                     /locus_tag="SALB_00471"
     CDS             8706..9665
                     /codon_start=1
                     /gene="pamD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 197.8; E-value: 3.9e-60)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00471"
                     /product="Ketoacyl-acyl carrier protein synthase III"
                     /protein_id="AJS09386.1"
                     /sec_met_domain="fabH (E-value: 5.9e-51, bitscore: 163.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGIWVGRGLSFRGFGHYFPRHSEEIPADLPDAPEMEAAVLGPD
                     LGVERRHLSDDTESVPYMAVEAGRHALRNAGLEACDLDLVVFSSWSQRRYAPEDGPRIA
                     MRLGAGRALAFDVCAACVGFVHSVQTAAAMLTSHRWRHALVICSDQFSRRLKPGRRGSY
                     VGGDGAGAAVLEVGAPDESRLRDSVVLSYGEHAGVSKARGSDGWTVSLPTISQVAAATA
                     GEATDLVLRRNDMTIADVDRVVPHPGSARISEELVRRIGVAPERVLTNLRTRGQTTSAT
                     IPSALSEFTESGELRKGNVILSPAAGAGWFSGALLYQL"
     gene            9718..10752
                     /gene="pamE"
                     /locus_tag="SALB_00472"
     CDS             9718..10752
                     /codon_start=1
                     /gene="pamE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 251.9; E-value: 1.4e-76)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00472"
                     /product="Ketoacyl-acyl carrier protein synthase III"
                     /protein_id="AJS09387.1"
                     /sec_met_domain="fabH (E-value: 5.2e-60, bitscore: 193.6,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPETRSPLDGGGPPVVLSGVGHYFPGEPVTNDHFARLPELDVDDA
                     WIRAYTGVRTRHWAGPEERFAEMGVKAARRALDDAGLDISDVDVIVGTSATARPRANPS
                     SLGNNYMDISLPVQRQLGARDAFCFDVTAVACAGFLYASVVARGLLATTGARTALVVCA
                     ESPHAILNFGFKNSALFGAGAAAAVWRRGESSGGGADGLPTRSGMIDVVLRADGRYYDA
                     FDIDENDKMVMRGGVLSEVTPDMLVDAGETVLKRNGLAPEQISWCIPHQANTNLLYPMA
                     DRLGIPRERMLLNLPRRGNTSSVGMPSALSEYVGDGTVKPGELLLGVSIGRGLSWGAMV
                     FRYQ"
     gene            10806..11600
                     /gene="pamO"
                     /locus_tag="SALB_00473"
     CDS             10806..11600
                     /NRPS_PKS="Domain: PKS_KR (7-177). E-value: 3.8e-11. Score:
                     35.1. Matches aSDomain: nrpspksdomains_SALB_00473_PKS_KR.1"
                     /codon_start=1
                     /gene="pamO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     184.9; E-value: 3e-56)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00473"
                     /product="Ketoacyl-(acyl-carrier-protein) reductase"
                     /protein_id="AJS09388.1"
                     /transl_table=11
                     /translation="MSDSRNALVTGGTRGLGLAVARLLVARGWRTTVLGLDPGRLEKVR
                     AMAEAEGLDLRAVRADVTSEESVREVFADLTRSEPLHLCVNNAGRNLSRLLLREPREGS
                     GAELLTHPLDDWEQTLRLCLTGVFLVGREAAAGMVRHGVPGAIVNVSSGLAAGAYGQSA
                     YTAAKAGVEALTRTWSYELGPYGIRVAAVAPGVMDGEALREKSTAFPRHARYMDGLKRF
                     VPLGRWGTEEEIADAVCFAAENPYITGSVIRVDGGGPPGWVP"
     CDS_motif       10827..10898
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SALB_00473_0001"
                     /evalue="5.70E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="SALB_00473"
                     /protein_end="31"
                     /protein_start="7"
                     /score="22.2"
                     /tool="antismash"
                     /translation="LVTGGTRGLGLAVARLLVARGWRT"
     aSDomain        10827..11336
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SALB_00473_PKS_KR.1"
                     /evalue="3.80E-11"
                     /label="SALB_00473_PKS_KR.1"
                     /locus_tag="SALB_00473"
                     /protein_end="177"
                     /protein_start="7"
                     /score="35.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVTGGTRGLGLAVARLLVARGWRTTVLGLDPGRLEKVRAMAEAEG
                     LDLRAVRADVTSEESVREVFADLTRSEPLHLCVNNAGRNLSRLLLREPREGSGAELLTH
                     PLDDWEQTLRLCLTGVFLVGREAAAGMVRHGVPGAIVNVSSGLAAGAYGQSAYTAAKAG
                     VEALTRT"
     gene            11685..12695
                     /gene="pamK"
                     /locus_tag="SALB_00474"
     CDS             11685..12695
                     /codon_start=1
                     /gene="pamK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 198.3; E-value: 2.8e-60)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00474"
                     /product="Ketoacyl-acyl carrier protein synthase III"
                     /protein_id="AJS09389.1"
                     /sec_met_domain="fabH (E-value: 1e-46, bitscore: 150.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPNADATSFSSMTTGLHGIWEDAGIRFTGFGHYFGSEEIHNHGV
                     ENATTSHVEDRVIGGVGVRTRYRANDDETPVFMAAQASRQALEQAGVDADDIDVMVVSH
                     WTDRNYVHEVGALTAAELGMKGSMAFEVCGSCAGFIQAVHTAASFLTAPTGYRKALVAT
                     TERVTRRVRPGSKGSMLVSDGAGACVLEATPGGSPGLIDSVFHTDGSLAHMSAASGDKG
                     WVKSHPDLNDVALAHISDTVEEILGRNKLAIGDIDWLIPHSGTEPLAKGIQHNLGADPA
                     RVLTNLAFRGNVSSASIPTTVSELRERGVVKPGDLVLSPSIGGGVWCWGSLLYRI"
     gene            12712..14007
                     /gene="pamJ"
                     /locus_tag="SALB_00475"
     CDS             12712..14007
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (79-395). E-value:
                     9.8e-24. Score: 75.8. Matches aSDomain:
                     nrpspksdomains_SALB_00475_PKS_KS.1"
                     /codon_start=1
                     /gene="pamJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 220.8; E-value:
                     5.2e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00475"
                     /product="Ketoacyl-acyl carrier protein synthase II"
                     /protein_id="AJS09390.1"
                     /sec_met_domain="t2fas (E-value: 1.5e-49, bitscore: 159.2,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTKGPRDALVTGMGFCLPGRTAPTATPEQFWTAVAHGDSFLAQ
                     DDGTYFGSVPLDPDSVAARLPEIPPRFVEKYSDIHLYGLLALLEACEDAALDWRSGALG
                     EAAVLAGRNATADAIVDTYLPVLLADTRNISPREARSILFRNVLNAVMSDVETTQAGLV
                     GATGPSYTLSCGCASSSVLLGNAARMIAAGETDIAVVTGADYWRESRLRQYADLEARSV
                     TGSEPQTATLVDEPMRPYDQRAAGLNYGNGAATLILESREHARRRGARTYGRLLGQTTT
                     RNAQPNLALDVEGTGAVRAARSCMAGIASPDEIDYVNGAATGDRAFNLMEGNIMPAIFG
                     ERAARLPVTVQEAVFGHSGAPLGVIGVAATLQMMGHGHIAPTANCEKPADVCTFDPVPG
                     TQGRPARIDLALSLNYTIGSVASAILLGGTDD"
     aSDomain        12949..13896
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SALB_00475_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="9.80E-24"
                     /label="SALB_00475_PKS_KS.1"
                     /locus_tag="SALB_00475"
                     /protein_end="395"
                     /protein_start="79"
                     /score="75.8"
                     /tool="antismash"
                     /translation="HLYGLLALLEACEDAALDWRSGALGEAAVLAGRNATADAIVDTYL
                     PVLLADTRNISPREARSILFRNVLNAVMSDVETTQAGLVGATGPSYTLSCGCASSSVLL
                     GNAARMIAAGETDIAVVTGADYWRESRLRQYADLEARSVTGSEPQTATLVDEPMRPYDQ
                     RAAGLNYGNGAATLILESREHARRRGARTYGRLLGQTTTRNAQPNLALDVEGTGAVRAA
                     RSCMAGIASPDEIDYVNGAATGDRAFNLMEGNIMPAIFGERAARLPVTVQEAVFGHSGA
                     PLGVIGVAATLQMMGHGHIAPTANCEKPADVCTFD"
     gene            14000..15577
                     /gene="pamM"
                     /locus_tag="SALB_00476"
     CDS             14000..15577
                     /NRPS_PKS="Domain: PKS_KR (246-395). E-value: 1.3e-06.
                     Score: 20.3. Matches aSDomain:
                     nrpspksdomains_SALB_00476_PKS_KR.1"
                     /codon_start=1
                     /gene="pamM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     164.9; E-value: 3.9e-50)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00476"
                     /product="Ketoacyl-(acyl-carrier-protein) reductase"
                     /protein_id="AJS09391.1"
                     /transl_table=11
                     /translation="MTEHTPPGAGPVLETGSLAPVGRRVLLESPPGADHTRAVREVWER
                     HGFHVTHDESAHMTQPPDVYCVVAIGNEALGARPSPPLRRPHVARVLKAMARRGEGRAV
                     LVTDTGPHVHDDAEPEAAAQRAADHAWWQHLAKHCASRGVLANTVRVGYTPFLGHELTD
                     EAAGELLRHLVTRRPVAPEELAAALRLLASRGFGNVAGETLPLDGGLDASIVPMPSARP
                     PRMDASAAEGDGAAVPDPFRLTGRVVLVTGASSGIGASIARECAARGADVVLAARRRPE
                     LEKLAAEVRELGRTAWVLTADLSDPARAADLVHEAWERAGGVDALAYGAGAVSFDGSGD
                     NSANRQQLLALNSLSYAGMCDALLEHWVAAGRSGAVAAVSSLAAVSAPVANLASYGLSK
                     AATAQFTTHFATSAARHKVRANSVLPGFVRTPMTDVTNPAFLEATNRLVPTGRMSEATE
                     VAALVCYLISPAAAGLTGTQLRVDGGGHCLAGLPNLAPPEHTLRGRNPAVTPCVPRPRP
                     AVPEGDHR"
     CDS_motif       14738..14833
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SALB_00476_0001"
                     /evalue="9.30E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="SALB_00476"
                     /protein_end="278"
                     /protein_start="246"
                     /score="18.3"
                     /tool="antismash"
                     /translation="VVLVTGASSGIGASIARECAARGADVVLAARR"
     aSDomain        14738..15184
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SALB_00476_PKS_KR.1"
                     /evalue="1.30E-06"
                     /label="SALB_00476_PKS_KR.1"
                     /locus_tag="SALB_00476"
                     /protein_end="395"
                     /protein_start="246"
                     /score="20.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVLVTGASSGIGASIARECAARGADVVLAARRRPELEKLAAEVRE
                     LGRTAWVLTADLSDPARAADLVHEAWERAGGVDALAYGAGAVSFDGSGDNSANRQQLLA
                     LNSLSYAGMCDALLEHWVAAGRSGAVAAVSSLAAVSAPVANLASY"
     gene            15574..16401
                     /gene="pamN"
                     /locus_tag="SALB_00477"
     CDS             15574..16401
                     /NRPS_PKS="Domain: PKS_KR (10-185). E-value: 6.7e-12.
                     Score: 37.5. Matches aSDomain:
                     nrpspksdomains_SALB_00477_PKS_KR.1"
                     /codon_start=1
                     /gene="pamN"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     171.8; E-value: 3.1e-52)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00477"
                     /product="Ketoacyl-(acyl-carrier-protein) reductase"
                     /protein_id="AJS09392.1"
                     /sec_met_domain="adh_short (E-value: 4.5e-32, bitscore:
                     101.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEDRPLKGKVALVAGASSGIGASIARALAAAGASVALVARRKDQ
                     LACVERDVAGHEVPAVTLIADLSADGVPKETVTAAERALGPVDILVNNAALARTGPIHD
                     TNPRHWRQAFHLNLDVPFLLARTVLPGMRERGHGWIVNISSEGSLLQADWSAPYSITKR
                     ALNALTAQIDLENRHLGVRAIAVLPGWVRTDLAQDPESLGVGVTDLLDPSDIADVVLWA
                     ITRPPAVSIGPLIPVRPVSRSAQTLVNWEQYLRTLRHYDASGGHMVDVPGIPE"
     aSDomain        15604..16128
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SALB_00477_PKS_KR.1"
                     /evalue="6.70E-12"
                     /label="SALB_00477_PKS_KR.1"
                     /locus_tag="SALB_00477"
                     /protein_end="185"
                     /protein_start="10"
                     /score="37.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVAGASSGIGASIARALAAAGASVALVARRKDQLACVERDVAG
                     HEVPAVTLIADLSADGVPKETVTAAERALGPVDILVNNAALARTGPIHDTNPRHWRQAF
                     HLNLDVPFLLARTVLPGMRERGHGWIVNISSEGSLLQADWSAPYSITKRALNALTAQID
                     LENRHLGVRAIA"
     CDS_motif       15610..15699
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SALB_00477_0001"
                     /evalue="1.50E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="SALB_00477"
                     /protein_end="42"
                     /protein_start="12"
                     /score="14.4"
                     /tool="antismash"
                     /translation="LVAGASSGIGASIARALAAAGASVALVARR"
     gene            16398..18101
                     /gene="pamL"
                     /locus_tag="SALB_00478"
     CDS             16398..18101
                     /NRPS_PKS="Domain: AMP-binding (46-453). E-value: 1.7e-80.
                     Score: 262.5. Matches aSDomain:
                     nrpspksdomains_SALB_00478_AMP-binding.1"
                     /codon_start=1
                     /gene="pamL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     315.8; E-value: 6.9e-96)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00478"
                     /product="Hydroxyl acids CoA ligase"
                     /protein_id="AJS09393.1"
                     /sec_met_domain="AMP-binding (E-value: 2.7e-84, bitscore:
                     273.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPTTSAATAARDLDVAADRLVEILPPGDARVPDAEHCVTGALL
                     AARAEAHPDRVYAVFEDGTHWTYGQAYDDARTTAAALYRLGVRQGDTVLCWLPNGLDAL
                     RVWYGVNLLGAVHVPVNTAYRGALLEHVLDNSGARVLVVHALLVERLQHIGDSRLQEVV
                     VLGGGPDAPWPDALPGAPRVHGPAALRGLPEDFVPPERPVAPWDTMAVIYTSGTTGPSK
                     GVLVSYVHHYSTVTALLDDDIGEDDRYLLNLPLCHGGGTEVAYCMLLFGGSIVVTENFR
                     TGEFWDVVRRHGVTMCTLLGAMVDFLLGLAPRPDEAEHPLRAACVIPLTRQALDFGRRF
                     GVDVYTGFNMSETSAPLVSPLNPQRTGSCGRPRPGVQCRVVDANGIDVPDGSVGELVLR
                     ADRPWSLFHGYHAMPEATAGAWRHGWFRTGDAVVREPGGDYFFVDRIKDAIRRRGENVS
                     SMEVEAELLSHPAVAFAAAVAVPSDFAEDEILAALVLRPGARFEPEEFIGYLRPRMAHF
                     MVPRYLRVLSELPVTDTGKVRKETLRAQGVTPDTWDRVAAGIEVTRDRIR"
     aSDomain        16536..17756
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SALB_00478_AMP-binding.1"
                     /evalue="1.70E-80"
                     /label="SALB_00478_AMP-binding.1"
                     /locus_tag="SALB_00478"
                     /protein_end="453"
                     /protein_start="46"
                     /score="262.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ARAEAHPDRVYAVFEDGTHWTYGQAYDDARTTAAALYRLGVRQGD
                     TVLCWLPNGLDALRVWYGVNLLGAVHVPVNTAYRGALLEHVLDNSGARVLVVHALLVER
                     LQHIGDSRLQEVVVLGGGPDAPWPDALPGAPRVHGPAALRGLPEDFVPPERPVAPWDTM
                     AVIYTSGTTGPSKGVLVSYVHHYSTVTALLDDDIGEDDRYLLNLPLCHGGGTEVAYCML
                     LFGGSIVVTENFRTGEFWDVVRRHGVTMCTLLGAMVDFLLGLAPRPDEAEHPLRAACVI
                     PLTRQALDFGRRFGVDVYTGFNMSETSAPLVSPLNPQRTGSCGRPRPGVQCRVVDANGI
                     DVPDGSVGELVLRADRPWSLFHGYHAMPEATAGAWRHGWFRTGDAVVREPGGDYFFVDR
                     IKDAIRRR"
     CDS_motif       17028..17078
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SALB_00478_0001"
                     /evalue="2.60E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="SALB_00478"
                     /protein_end="227"
                     /protein_start="210"
                     /score="20.0"
                     /tool="antismash"
                     /translation="VIYTSGTTGPSKGVLVS"
     gene            18085..19068
                     /gene="pamH"
                     /locus_tag="SALB_00479"
     CDS             18085..19068
                     /codon_start=1
                     /gene="pamH"
                     /locus_tag="SALB_00479"
                     /product="Metal-dependent hydrolase (resistance)"
                     /protein_id="AJS09394.1"
                     /transl_table=11
                     /translation="MTASAEPAAPAHRVVDVCALSLDRECWRTYFRGLGAVAPAYLRAF
                     GRHATAVFGADYPRFRARLDAGDQDGAVDLLVSGQPERVDSDALLKTMDDNGVVHQILM
                     SCGGATADGDDVNSRVAAVAAKAPDRLRAWAGIDLTDPGRAVAELERCHLLGMRGFAVT
                     PFWQGVDPRDTAYDPVYRRARELGMPLWLHTGHHFSRHAAELCHPRNVDWIALRHPGLP
                     IVAGHAAWPWTLELISIAQRHRHVYLDISSHRPQWMARPGSGWESLLLYGTTVLRDRVL
                     FGSATWVNADPVAALARQVAALDLGDEVTDLWLYGNAARLLGLGPG"
     gene            19165..20511
                     /gene="pamX"
                     /locus_tag="SALB_00480"
     CDS             19165..20511
                     /NRPS_PKS="Domain: Aminotran_3 (27-370). E-value: 4.5e-76.
                     Score: 247.9. Matches aSDomain:
                     nrpspksdomains_SALB_00480_Aminotran_3.1"
                     /codon_start=1
                     /gene="pamX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 314.2;
                     E-value: 2.2e-95)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00480"
                     /product="Aminotransferase"
                     /protein_id="AJS09395.1"
                     /sec_met_domain="Aminotran_3 (E-value: 5.4e-73, bitscore:
                     236.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDPADYALWNSGVPRPYLKALSRDDLLTEGDGVRVRDSGGRWYL
                     DGRSGLWNVTLGYGNTRVKEAIKQQVDRLPFANSYGYGRPAQVTVDCAEALVRHLPEGI
                     NHVRFASNGAQAVEMALQLSRFLRLRAGQPERMAVFAMWDGFHGQGPGAGMVTGVPYLH
                     HQTGPMLPEVHHAPGPFSAGATQGVSDMERLITEFGPERVTAVIVEPVVGEGGHILSPE
                     YLGSLGRFCRQHDIHLIFDEVVTGMGRVGDFTRAGQLPDVTPDIITLGKGITSGYVPMS
                     AVAIHDRLYEQLHERTTGDTALSVGSTNDGHAVAAAAALAVIGALTEDGVLENVRRREA
                     DLLSALGKLQAQHPELRAFRALGLFCGLELGEPGGPSWSPGKVNQLRMTLESRGVLSSS
                     LRVVPNLMLMPPLVITEDDVAEIADALDGALTDVKSGRRPESGFAKAMG"
     aSDomain        19246..20274
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SALB_00480_Aminotran_3.1"
                     /evalue="4.50E-76"
                     /label="SALB_00480_Aminotran_3.1"
                     /locus_tag="SALB_00480"
                     /protein_end="370"
                     /protein_start="27"
                     /score="247.9"
                     /tool="antismash"
                     /translation="LTEGDGVRVRDSGGRWYLDGRSGLWNVTLGYGNTRVKEAIKQQVD
                     RLPFANSYGYGRPAQVTVDCAEALVRHLPEGINHVRFASNGAQAVEMALQLSRFLRLRA
                     GQPERMAVFAMWDGFHGQGPGAGMVTGVPYLHHQTGPMLPEVHHAPGPFSAGATQGVSD
                     MERLITEFGPERVTAVIVEPVVGEGGHILSPEYLGSLGRFCRQHDIHLIFDEVVTGMGR
                     VGDFTRAGQLPDVTPDIITLGKGITSGYVPMSAVAIHDRLYEQLHERTTGDTALSVGST
                     NDGHAVAAAAALAVIGALTEDGVLENVRRREADLLSALGKLQAQHPELRAFRALGLFCG
                     LEL"
     gene            20560..21381
                     /gene="pamY"
                     /locus_tag="SALB_00481"
     CDS             20560..21381
                     /codon_start=1
                     /gene="pamY"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248:methyltransferase (Score: 74.2; E-value:
                     1.9e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00481"
                     /product="Methyltransferase"
                     /protein_id="AJS09396.1"
                     /transl_table=11
                     /translation="MSDDMSNAHTDRKTSKQWQEEAAEEWDRYADIWDSWTPDDSRDDA
                     EEAADFLAGLAKGGTALELGIGTGRVALPLAQRGVRVAGIDASPKMLLKLKEKPGGDRI
                     EVFEGNFADVDVKEDYDVIFIALATLFVLPDQDEQARCLANSAKRLKPGGRLVVQNIVP
                     DMTYYQRGRQNDYGMTEPFRISGRLAGHPRLAWFEMNHVDPTTQMVKRTDVIMSEKGNR
                     IIAATMRFVWPSEQDLMARLGGLTLEDRWGGWRKEPFHYDSRDAVSVYRKQ"
     gene            21599..22405
                     /gene="pamS"
                     /locus_tag="SALB_00482"
     CDS             21599..22405
                     /NRPS_PKS="Domain: ECH (23-238). E-value: 2.6e-50. Score:
                     162.9. Matches aSDomain: nrpspksdomains_SALB_00482_ECH.1"
                     /codon_start=1
                     /gene="pamS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 219.1; E-value:
                     8.6e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SALB_00482"
                     /product="Enoyl-CoA hydratase"
                     /protein_id="AJS09397.1"
                     /transl_table=11
                     /translation="MSEEFGQDRPAEAGSGSGTDVLVERRGPVLVIQLNRPRVRNALTR
                     AMAERLAAAFTELDARAELRLGVLTGTPPAFCSGMDLGAFARGERASLPGRGFGGLTEQ
                     PPSKPLIAAVEGAAVGGGFEMVLACDMVVAADDAVFGLPELRRGLVAAAGGLLRLPRAI
                     APAVAMEMALTGEPIDAQRAFALGLVNRVVAPGTALTAACELAEKIAAHADHAVLASKG
                     VLARVRDGELADEYRSHRELLSGILDSPGARAGAREFVRERPGGPR"
     aSDomain        21668..22312
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SALB_00482_ECH.1"
                     /evalue="2.60E-50"
                     /label="SALB_00482_ECH.1"
                     /locus_tag="SALB_00482"
                     /protein_end="238"
                     /protein_start="23"
                     /score="162.9"
                     /tool="antismash"
                     /translation="ERRGPVLVIQLNRPRVRNALTRAMAERLAAAFTELDARAELRLGV
                     LTGTPPAFCSGMDLGAFARGERASLPGRGFGGLTEQPPSKPLIAAVEGAAVGGGFEMVL
                     ACDMVVAADDAVFGLPELRRGLVAAAGGLLRLPRAIAPAVAMEMALTGEPIDAQRAFAL
                     GLVNRVVAPGTALTAACELAEKIAAHADHAVLASKGVLARVRDGELADEYRS"
     gene            complement(22430..23077)
                     /gene="pamR1"
                     /locus_tag="SALB_00483"
     CDS             complement(22430..23077)
                     /codon_start=1
                     /gene="pamR1"
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 95.9; E-value:
                     3.2e-29)"
                     /gene_kind="regulatory"
                     /locus_tag="SALB_00483"
                     /product="Response regulator LuxR family"
                     /protein_id="AJS09398.1"
                     /transl_table=11
                     /translation="MQALGVLVVDRHPVVRYALSSLLDTRVAWTAEAATSDEAWNAVTT
                     SCPGVVVLELELDGATSGADLCQRVKAMEDAPRVVVFTGDTSPGAVVSAISAGADSFLH
                     KSVGSSELVDAVVRTYNGQRMWILGKNEREHVDVRSVMPDGLPAITRREEQVLSLVLRR
                     YTNEEIASELSLASQTIKNQVSSALRKLGVSGRRELFRKYSSPTGVTTGARG"
     misc_feature    complement(23066..23068)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 tgtgccaggg cgtcaggagt cctgggaacg catctgcccc atgccggaca ccatgcattc
       61 gaggccgtcg tggaatcgct ggcccgtgct gctcgaagcg ctgcgcttga cgtagtcggc
      121 cagggaagcc gggtgggact gggtcgccat gccgaggtag gggccgaggc gactcaccca
      181 ctcctcctcg ctctcggcgc tctggcgcgc catcgcctgc caggacgcct cggacaaggc
      241 ggcgcccacg gtgtagtagt agatcgccga gagcgctgag tccagctgcc tcggggagaa
      301 gtgggcctgc tccaggatct cgatgatggc gctggtgtgc gccagcgcgc ggggccccac
      361 cggggggtga ccgcccatca gctcgatcat ccaggagtgc cgcagcagta cctcgaacaa
      421 atccgtcgcg cccgccttga tgtcgtcgcg ccagtccccc gtgccggacc gggaaggcgg
      481 gtcggggaac accgcgtcga tggccagttc cagcaggtcg tccttggtcg acacgtgcca
      541 gtacaacgac atcggtgccg agttcagcga gtccgcgagc tgacgcatgc gcaggttgcg
      601 gacacccccc tcatccagga gacgcaccgc cgcctgcacg atctgttcac ggctcagcgg
      661 ctgcctcgcc ggccgctgct tcacctcgcg cagccagatc gagccgggtt ggcctttcgg
      721 tgtgttttct cgtccagaag tttcattcac agccctatgc taacgcagtc tcgtacgacg
      781 tacgatagct ggtatgacgt acgagaccag ttgacggaat cccgaaggag gccagtcatg
      841 gacggcgtgg tgcatgagca gcagggcgcg ggccgcggag gaggtgaggg cggtgacgac
      901 ggcggcgtcc ccggggcgaa aaaccgatgg gcggtactgg gcgtcctctc gctgagcctt
      961 ctcgtcgtcg ccctcgacct gacggtgctg aacgtggccc tgcccacgct cagcaccgaa
     1021 cttcgaccct cgtcggtgca gttgctgtgg atcgtcgacg tctactcgct cgtcgtcgcc
     1081 ggcctgctca tcagctgcgg cacgctcggc gaccgcctgg gccgcaaacg tttcctgtgc
     1141 cttggcttca tcgtcttcgg cggcgcatcg gccgccgcgg cctgggcgag cgggcccgcg
     1201 atgctgatca cggcccgcgc gctgctcgga atcggcgccg cgatcatcat gccgtcgacg
     1261 ctctcgatca tccggaacgt gttcaccgac cgcaaggagc ggacggtggc gctcgccgtg
     1321 tgggccacca tgtccgcggc cggtgccgcg gtcgggccgg tggtcggcgg tgtcatgatc
     1381 gagcacttct ggtggggctc ggtcttcctg atcaacgtgc ccatcatggt cctcgccctt
     1441 atcgccgcgc tgaccctggt gccggagtcc cggcatccga atccgccgcg ctgggacacc
     1501 gccggagccc tgctgtccgt caccggtctg atctccctcg tgtacgcgat tcagcacggc
     1561 ggcgcgaagg gcctggaggc gcagacgatc atcacaggcg tgctcggcct ggtgctgctc
     1621 accgccctgg tggtgcgagt gctgcgcatc cgcgatccgc tcttcgaccc gaccctcttc
     1681 cgcgaccgcg cgttctccgt ggcggtggtg tccgtggtcc tcgccatgtt cggcatgggc
     1741 gggctgatgc tgctgctcac gcagcactgg cagttcatcg gcggcgcctc gccgatggag
     1801 tcgggccttc agctgctgcc gttgctcctg gccaccatga tcggggcccc gatcatgtcc
     1861 gtcatcgtcc cgaggtacgg gacgcggtac gccatgatga tcggcatggg cctgatcggc
     1921 gccgcgttct tcgtcctgat gaacgtcgag cccgacaccg agtactgggt cttcgccatc
     1981 gccctcgcgg gcatcggcgc cggcgcgggt tgcgccatga cggccgcgtc ggacgccatc
     2041 atgtcgacgg ccgacgcgga taccgcgggt ggcgccgcgg gcatcgagga gacctcctac
     2101 gaactcggca acggactgag cgtggcgatc atgggcagcg tggcgtccgc gctcttccgc
     2161 agggagatgg acgaccccgt cgccggggtg gaccccaagg ccatggatgc cgcgcgcgaa
     2221 ggcctccccg acgccgtcgg agtggccggt gccctgcccg gtgccgtcgg ggaggagttg
     2281 aagcggcgag ccgacaacgc gttcacggac gcgttcgggg tcacgtcgct gtgcaccggc
     2341 gtcatcctcg tggtggtggc ggtcgccgtc ttcctgttca tcccgccctc ggcggggcgg
     2401 atcaccccgg cgaccgaggg cggcggtgac gcgcccgagg acggcgtgga tctggtgaaa
     2461 caggaatcga gggagtccgc cgacggccgc ccaacgcccg tggaccggcc ctgaccacag
     2521 gaagcagccg gggcccgtaa cgggccccgg ctgtccggtg gtcgtgccca ggtccgtgcg
     2581 caccgcgctc tccagggacc tgggcacggc tcaggatgct tgcttgcggc gctcgacgag
     2641 ttcgacgatc ctgtcgagcc gctccagctc gacgacctcg tcgtcggtga tctccacgcc
     2701 gaatcccttc tccagggcga gggcgaactc gaccgacgcc agggagtcca ggccgaggtc
     2761 ctccagcgtg gagtccgggg ctatccggtc ctcggagatc ttgaattcgt tggtgagcag
     2821 ggacttgacc gattcgtaca ccgtttcctc cgggggacgc tgcgtcggtg ggtgggacgg
     2881 gcggttggtc cgcctcagcc gcggtacgta tgcacggcca gggccgtgac gtccggccac
     2941 gtcagagagg ccgcgcccca ggcgagcccg ccgccgaacg ccgcgagcag cacccggtcg
     3001 ttcgtccgca gcctgcccgc cgcggccgag tcggcgagca gcaggggaag ggacgcggcc
     3061 gaggtgttgc cgacatgctc gatgttggac aggacgcggt cgcgcgggac gcccagttcg
     3121 tcggcgacgg cttcgctgat gcgtgcgttg gcctgatggg tcgccagacg gtcgacgtcc
     3181 tcgaccgtcc agccggagcg ctcgatgacc tcgcgcgccg actgtgccat gcgctccttc
     3241 gcgtgccggt agaccttgcg gccctgcatc tgtaggtggt gatcgctcgg ctcgggcacg
     3301 gtccgggcgg cgcgctgccg ggcaccgccc gcggggatct ggatgaggtc gctgtgcgtg
     3361 ccgtcgctgc cgagccggat cgggccgatg gctcccggct cgtcggggtc accggcgcgc
     3421 agcacgacgg ctccggcggc gtcgccgaag atgacggccg tgttgcggtc ctgcgggtcg
     3481 acgatggcgg agaaggtctc ggcgccgatg accaggacgc ggtcggcgaa gcccgcggcg
     3541 atcgccccga ctcctgccga cagcgcgtac aggaatccgg cgcagacggc ggcgacgtcg
     3601 tgcgcggcga cggggccgag cccgagcgcc gccgcgacct cgggggcggt ggccgggcag
     3661 aggcggtccg gggtcgccgt cgcgaggacg accgcgtcca cgtcgtcgcg gccggccgac
     3721 ttcagggcca gccgccccgc ctccacggcc agttcccgcg tggccatgcc cggcgggacg
     3781 gtgtgccgct cggcgatgcc ggtgcggctg cggatccagt cgtcggtggt gtcgaggcgg
     3841 gcttccaggt cggcgttggt gaccgtgccg ggcggcaccc agccggcgac gcccgccagc
     3901 acggccgcgc gtgtcctgtt gtggtccatg tccgcgggcc tcacgccttc cccagcagga
     3961 tcgcgctgct gaccatgccg acggtgtagt tgaaggagag cgcgtgatcg atgcgcagtg
     4021 gccgggcggt ggtgcccggc accgggtcga agaggcaggt gtcgtccggg tcgacgcagc
     4081 cggccgtcgg gaacaccagg tcgcgctgga tcatcaggga cgtggccgcc actcccagag
     4141 cgccgagcgg accgccgttg tgcccgaagc aggcctcctg cacggtgacg ggcatcgcgg
     4201 tcgcgcggtc cccgaagagg ctgcgcatga tgttcgactc cgtctcgtga aagacgcggt
     4261 cgccctcggc ccctccgttg acgtagtcga tctgttcggc ctcgacgagg cccgccatgg
     4321 cgtcccggga ggcctggacc atgccggtcc ccgcacggtc gatggcgaag gcgctgtgct
     4381 gcgggctgcg ccgggtgcgc tgcgccagca ttcgggagta gggggtcgcg ccgcgccgct
     4441 cggcatgcgc gcggctctcc acgacgagcg tgatggagcc gttgcccatg ttggagcccg
     4501 gggagttctt gtcgtacggg cgcatctgcg cgcccatcgc cagtgcggcg tcctccatgg
     4561 cgtcgacggt gatgccctcc tcggcgctca gctcggcgta ccggtcgagg aggtcggcgt
     4621 agtgccgcag gaagccgagg ccgaacacgt cggcgccggt gaccaccgcg acctccacct
     4681 caccgtcggc gatcatccgg cccgccatgc ccaggagcac cgcggaggac gtacagccgt
     4741 tggagacggt gaagttgggg ccggtcccgg ccacgaccga cacctggacg ttggccacgt
     4801 ccatggggat gccggtcagg gcgagacggg tgcccagttc gttgatctcg tccttggtgg
     4861 cttgggtgcg atcggtgttg aggatgtcgg cgtactgcgc cgaccagcag tcgccgccgt
     4921 cccgggctgc gaggatcgcc gcttgcgaca gggcgcccga gcgccagtcg agtccggcgt
     4981 caccgcacgc ctcggccatg gagatcaggc cgagcaactg caccggggaa tagagtttca
     5041 gagcctttac gggaagttcg ggataacgct ccttcacatc cgcgatatcg gtgcgcactt
     5101 gaccgaagaa gacgccgtca ttctccacgt agcaggcgcc ggtggagacg atgtccagga
     5161 attgcgcgga cgtcgcgcac agtcctcctg ggccgggcag ggcgaatccc atgcccgtga
     5221 tcagtgcgtc gcgaccggga tcctgctgct gatgcgccat gagactccct gtgttgcgtg
     5281 ccgctgtcga caggccgccg acgctagagc ggtgcgggtc ggggcgtaac cggctcctgg
     5341 tacccggttt ccgccaccac aggtatcagt agtactgaaa tcaataattg gtacttcaag
     5401 taccacaggg ggattctccc gggtaccggt gggccgatgt ccctcgaatt cccggcggat
     5461 agctttcccg tatggctgca caggctgaat ccgctgcacg gaaaaaccgc ggggactccg
     5521 tactcgtcac cggtatcggc gtcatgctcc ccggcgcgac ccatgtcaac gaattctggc
     5581 aggacgtgcg cgacggcaat tcacgactcg gccggctgac gcgctgcgta ccgggcagga
     5641 ccggggtacg cgtggccggc gagctgcgcg acttcgacca ccggaagttc ctgccggagc
     5701 tgaacgagaa gttcgcgggc cggtacacgc gcgacgcgct ggtgaccatg tcggccgtcg
     5761 aggaggcccg ccgtgacgcg ggtctcgggt ccggcgagat cgacccgctg cgcctctccc
     5821 tcatcgcctc gtcctcacgc ggccccctgg agtgggtcag ccaggcgctg cgggaggacg
     5881 acagcgtcgg caacagagaa ggccacgaag accacgaggc gggcagcacg gcccacttcg
     5941 gtgacagcgg cgccatgctg cgcggcatgc cgggcgcccc ggcgacgctg tcggccatct
     6001 acggcgacgt gcgcggactc gtcaccacgc tcagctccgc ctgcgtgggc gggcaccacg
     6061 ccatcggctt cgccgccgac ctcattcgcg cgggcaccgc cgacgccgtg gtcgtggtgg
     6121 gctacgaatt ccccctgacc cccctggtgt tccagtcctt ccaggcgatg ggcgaccgcg
     6181 tcctgtcggc cgagtcggcc gacccccgcc gcgcgatccg cccctacacc cgcgaccgcg
     6241 agggcttcgc cttcggcgag ggcgccgtcg ccctgtgcct ggagcgggag agccatgccc
     6301 gggcacgcgg cgcgggcggc tacgcccgct tcctgtccca cagggcgctg aacgaggcaa
     6361 cccacccctt cggcatggac atgagcgggc agatcaccgc gtccgccgtc gccggggcgc
     6421 tccaggacgc gggccgcacc ccgcgggacg tcgactggtt ctgcgcgcac ggcaccgcca
     6481 cgccgaagaa cgacgtggcc gagagccgca tgctcggtgc cctgtacgag ggccgcccgc
     6541 ggtccgcctg gccgcccctc agctccgtca agccggtgta cggccacctc ctgggcgccg
     6601 ccgccctggt caacgcggcg gccacctcgc tggccctgca ccaccagtgc ctgtgctcga
     6661 ccgccaacta cgcggacgcc gtgcccgacc cggagtgcga ccacgaccac gtcgccgagg
     6721 gggcccgcgc gacccgcacc gaactcgcgg tgtcgctggc cttcgccatc ggcagccaga
     6781 cctcggtact ggcactcggc gccgcatgac cggtgccgaa cccgcgcgga ccgaacccct
     6841 gaaggagacc atgagcacgc acagcggcac cgcgccacgc cccgacatcg tccctgacgt
     6901 cgtccccgac gtcgactccc tggtgtcccg gtacgtgacg ccggggatgc atctgcacct
     6961 ggccatgacg atggcgcggc ccaacgccat ggtctacgcg ctggcacggc ggttcgcggg
     7021 ccgcggcgag ttcaccgtca gcacgtcggc cacgcacacg gccatgcacg cgctgaccat
     7081 gtcgggcgcg gtcaggcatc tgatcacctg cttcctcggt gacacctacc ccacgccgcg
     7141 ccccaacccg ctctaccgcg acctggcccg cggcatcccc ttcacctgcg agttgtggtc
     7201 cctgctcagc ttcacccagc gcctgatggc cggggccacg gggctgccgt acgccgtgac
     7261 gtcctcgctc atcggcagcg atctggagcg cggtctcacc ggcgacggcc ccgggacacg
     7321 cccgctgccg gagggcgaac agccgctcgg cggaccgaag ttcctgcgcc tgcccggccg
     7381 gtcggccgaa gagcgcccgt tcggtctcgt ggagcggctg cgtccggacc tcaccctggt
     7441 gcacggcgcc tgcgcggacc ggcgcggcaa catcgtcctc gtgccgcccg cgggcgaggg
     7501 cgcctgggcc gcgtacgccg ccgaacaggg cgtgctcgcc tcggtggagc gcatcgtgcc
     7561 cgacgacttc accgacgggc accccgaacg gatcgtcatt cccggccggc gcgtgctcgc
     7621 cctgtgcgag gcgccgctgg gcgcgcaccc gcagtcgctg cgcggtctcg ccaccggcga
     7681 cgagcgcggc gacgtgagcg ggtaccgcga cgactacgcc ttcctcaccg agctggtgga
     7741 ccggctggcc accgaggacg gcgccaagga gtggtaccgc gagtgggtgg aggagcccgc
     7801 cgggcacgcg cagtacgtac gcaagctggg cgaggcgcgc cgcgccgaac tgaccctcgc
     7861 ctcggggccg ctcacctctc gcgagcccgc cactcccccg gtgccgctcc ccgcgggagc
     7921 catcgccgcc gagcccgtga cgcgccagga gcggaccatc gtcctgggcg cccgcgccat
     7981 cgccgaccgg gtcacgcgcg acggctacga caccctgctc gcgggcatcg gcgtctccca
     8041 cctggccgcc tggctcgccg ccgcgctcct gcgcgaacag ggcgtgcggg tgccggtctg
     8101 cgccgagctg ggcttctacg gcatggaccc cgagcccggc gacgtcttcc tcttcagcca
     8161 gctgcacgcc acgcgttccc agcagctcgt gggcatcccc gagatcctcg gcggcatggt
     8221 gtcggcgaac ccgcgctgcc tgggcgtcct ggccgccggt gaggtcgacg cggacggcaa
     8281 cgtcaacacc agcctgctgg ccgacggacg ctggctgacc ggctccggcg gcgccaacga
     8341 catcgcgacg agcaccgact gcctggtgct gtccacggct tccccgcgca agttcgtcga
     8401 gcgggtcgcc tatgtcacca gtcccggtgc ccgcgtacgg gaagtggtca gccacttcgg
     8461 gcggttccgg cgcgagcagg acacacgggg ggccttccgc ctcgccacct ggctgccgct
     8521 caacgacggc ccggcctccc ccgaggaggc cgtggcggcg ctgacccgct ggccggtgag
     8581 cggcgcgggc tgcacggcgg aaccgcaggt caccgaggcg gagatcgcct ggctgcgcag
     8641 tctcgatccg caaggtttct acaggtgacg cgatccgcag gatcccacca ggtgaggagc
     8701 acggtgtgag cggtggaatc tgggtgggcc gcggcctgtc cttccggggc ttcggccact
     8761 acttcccgcg gcacagcgag gagatcccgg ccgacctgcc cgacgcgccg gagatggagg
     8821 cggcggtcct cggcccggac ctcggcgtgg agcggcggca cctgtccgac gacacggaga
     8881 gcgtgccgta catggccgtg gaggccggac ggcacgcgtt gcgcaacgcc ggcctggagg
     8941 cctgcgacct cgacctggtg gtcttctcct cctggtcgca gcggcggtac gcgcctgagg
     9001 acgggccccg gatcgcgatg cgcctcggcg ccgggcgggc cttggccttc gacgtgtgcg
     9061 ccgcctgcgt cggcttcgtc cactccgtgc agacggccgc cgcgatgctg accagtcacc
     9121 gctggcggca cgccctggtg atctgctccg accagttctc gcgtcggctc aagcccggtc
     9181 ggcggggttc gtacgtcggc ggcgacgggg cgggcgcggc cgttctggag gtgggggcgc
     9241 cggacgagtc ccggctgcgg gactccgtcg tgctcagcta cggcgagcac gcgggcgtct
     9301 ccaaggcccg cggcagcgac ggctggacgg tgagcctgcc cacgatctcc caggtggccg
     9361 ccgcgaccgc gggcgaggcc acggacctgg tgctgcggcg caacgacatg accatcgccg
     9421 atgtggaccg ggtcgtgccg catccgggct cggcacggat cagtgaggag ctggtgcggc
     9481 gcatcggcgt cgcccccgag cgggtcctga cgaacctgcg gacacgcggc cagacgacca
     9541 gcgccacgat cccgagcgcc ctgtccgagt tcaccgagtc cggcgaactg cgcaagggca
     9601 acgtgatcct gtcgcccgcg gccggcgcgg ggtggttctc gggcgccctg ctctaccagc
     9661 tctgacgcac cgacggacag cacacaacga cgggaagacg aggaaaggac ctcccccatg
     9721 cccgaaaccc ggtcaccgct cgacggcgga ggcccgccgg tcgtgctcag tggtgtcggc
     9781 cactacttcc ccggcgagcc ggtcaccaac gaccacttcg cccgcctgcc cgagctggac
     9841 gtggacgacg cctggatacg cgcgtacacg ggcgtgcgga cccgtcactg ggccggcccc
     9901 gaggaacggt tcgccgagat gggcgtcaag gcggcccggc gcgctctcga cgacgcgggc
     9961 ctcgacatct ccgacgtgga cgtgatcgtc ggcaccagcg cgaccgcccg gccacgtgcc
    10021 aacccctcct ccctcggcaa caactacatg gacatctccc tgccggtgca gcggcagctg
    10081 ggcgcccgtg acgcgttctg cttcgacgtg accgcggtcg cctgcgcagg attcctgtac
    10141 gcgagcgtgg tggcccgcgg gctgctggcg acgacggggg cccggaccgc cctcgtcgtg
    10201 tgcgcggaaa gcccgcacgc catcctcaac ttcgggttca agaactccgc gctcttcggc
    10261 gcgggcgcgg cggccgcggt gtggcggcgc ggcgagtcct cgggcggcgg cgccgacggc
    10321 ctgccgacgc gcagcggcat gatcgacgtc gtcctgcgcg ccgacggccg ctactacgac
    10381 gccttcgaca tcgacgagaa cgacaagatg gtgatgcgcg gcggggtgct ctccgaggtc
    10441 acgcccgaca tgctcgtcga cgccggagag acggtcctca agcgcaacgg cctggcaccg
    10501 gaacagattt cctggtgcat tccgcatcag gcgaacacca acctcctgta tccgatggcg
    10561 gaccgcctcg gaattccgcg cgagcggatg ctcctgaatc ttccgcgccg cggcaacaca
    10621 tcgagtgtgg gaatgccgag cgcgctctcc gaatacgtcg gtgacggcac ggtgaaaccc
    10681 ggcgaactac tcctgggcgt aagcatcggg cgcggcctga gctggggcgc catggttttc
    10741 cggtaccagt gaacggccgt accgccgcgg cgcacgcgac aaccgagagc gagaggtgaa
    10801 cggccatgtc cgattccagg aatgcgctgg tgaccggggg aacccgcggc ctcggcctgg
    10861 ccgtcgcccg gctgctggtg gcgcggggat ggcgcaccac ggtcctcggc ctcgacccgg
    10921 gacgcctgga gaaggtgcgg gccatggccg aggccgaggg cctggacctg cgcgcggtgc
    10981 gggccgatgt cacctcggag gagtcggtgc gggaggtgtt cgccgacctg acccggagcg
    11041 agccgctgca cctgtgcgtg aacaacgcgg gccgcaacct ctcccgtctg ctactgcgcg
    11101 aaccgcggga gggcagcggc gccgagctgc tcacgcatcc gctcgacgac tgggagcaga
    11161 cgctgcggct gtgcctgacg ggggtcttcc tcgtcggccg cgaggccgcc gccggcatgg
    11221 tgcggcacgg ggtgcccggc gccatcgtca acgtctcctc cggtctcgcg gcgggcgcct
    11281 acgggcagtc cgcgtacacc gccgcgaagg cgggcgtgga ggcgctgacc cgtacctggt
    11341 cctatgaact cggcccctac gggatcaggg tggcggcggt cgcgccgggc gtgatggacg
    11401 gtgaggcact gcgcgagaag agcacggcct ttccacggca cgcccgttat atggacgggc
    11461 tgaagcgttt tgtcccgctg ggccgttggg ggacggagga agagatagcg gacgcggtgt
    11521 gcttcgccgc ggaaaacccc tatatcaccg gatcggtcat tcgggtcgac ggcggcgggc
    11581 cgcccggctg ggttccgtaa cgacgccacc cgtgggtgaa ctacggcttt ttcgcggggt
    11641 acttcgagta cccgcggcat gaatcatcga gtactggagg ccagatgcag ccgaatgccg
    11701 acgccactag tttttcgtcc atgaccacag gcctgcacgg aatctgggaa gacgccggaa
    11761 tacgtttcac cggattcggc cactatttcg gctccgagga aatacacaac cacggcgtcg
    11821 agaacgcgac gacgagccac gtggaggacc gcgtcatcgg cggggtcggt gtccgcaccc
    11881 gctaccgggc caacgacgac gagacccccg tgttcatggc cgcgcaggcc tcccggcagg
    11941 cgctggagca ggccggggtc gacgccgacg acatcgatgt gatggtcgtc agccattgga
    12001 cggaccgcaa ctacgtgcac gaggtgggcg cgctcaccgc ggcggagctg ggaatgaagg
    12061 gctccatggc cttcgaggtg tgcggctcct gcgccggttt catccaggcg gtgcacaccg
    12121 cggcgtcgtt cctgaccgcc ccgaccggct accgcaaggc gctggtggcc accaccgagc
    12181 gggtcacgcg gcgggtgcgg cccggctcca agggctcaat gctcgtctcg gacggcgccg
    12241 gcgcgtgtgt cctcgaagcc acccccggcg gctcccccgg gctcatcgac tccgtgttcc
    12301 acaccgacgg cagcctcgcc cacatgtccg cggcgagcgg ggacaaggga tgggtgaaga
    12361 gccacccgga cctcaacgac gtcgccctgg cccacatcag cgacaccgtg gaggagatcc
    12421 tcggccgcaa caaactggcg atcggcgaca tcgactggct catcccccac tcggggaccg
    12481 agccgctggc caagggcatc cagcacaacc tgggagcgga cccggcgcgc gtcctgacca
    12541 acctcgcctt ccgcggcaac gtctccagcg cctccatccc caccaccgtc tcggaactgc
    12601 gggagcgcgg cgtcgtcaaa cccggcgacc tggtgctctc cccctccatc ggcggcggcg
    12661 tctggtgctg gggcagcctc ctgtaccgga tctgagcgaa gggccaatgc ggtgaccacg
    12721 accaagggcc cccgggacgc actcgtcacc ggcatgggct tctgtctgcc ggggcgtacg
    12781 gcgccgacgg cgacacccga gcagttctgg acggccgtcg cgcacggcga ctccttcctc
    12841 gcgcaggacg acggcaccta cttcggcagc gtccccctag acccggactc cgtcgccgct
    12901 cgactgccgg agatcccgcc gcgcttcgtc gagaagtact ccgacatcca tctgtacggg
    12961 ctgctcgccc tcctggaggc gtgcgaggac gccgcgctcg actggcgttc gggcgcactg
    13021 ggcgaggccg ccgtactcgc gggccgcaac gccacggccg acgccatcgt cgacacgtat
    13081 ctgccggtgc tcctcgccga cacccggaac atcagcccgc gcgaggcccg ctcgatactg
    13141 ttccgcaacg ttctcaacgc ggtgatgtcg gacgtcgaga cgacccaggc gggcctcgtc
    13201 ggcgccaccg gccccagcta cacgctgtcc tgcgggtgcg cctcctcgtc cgtgctgctc
    13261 ggcaacgcgg cccgcatgat cgcagcgggc gagacggaca tcgcggtggt caccggcgcc
    13321 gactactggc gcgagagcag actgcggcag tacgcggacc tcgaggcacg ctcggtgacc
    13381 gggagcgaac cgcagaccgc caccctcgtc gacgagccca tgcgccccta cgaccagcgg
    13441 gccgccggcc tcaactacgg caacggcgcg gccaccttga tcctggagag ccgcgagcac
    13501 gcgcggcgca ggggcgccag gacctacgga cggctcctgg gccagaccac cacccgcaac
    13561 gcccagccca acctcgccct cgacgtcgag ggcacggggg cggtgcgcgc cgcgcgctcc
    13621 tgcatggccg ggatcgcatc gccggacgag atcgactacg tcaacggcgc cgcgaccggc
    13681 gaccgggcgt tcaacctcat ggaaggcaac atcatgcccg ccatcttcgg tgagcgggcg
    13741 gcccggctgc ccgtcaccgt ccaggaggcc gtgttcggac acagcggggc cccgctcgga
    13801 gtgatcggtg tggcggcgac gctccagatg atgggccacg gccacatcgc cccgaccgcg
    13861 aactgcgaga agcccgccga cgtgtgcacc ttcgacccgg tgcccggcac ccaggggcgg
    13921 cccgcgcgca tcgacctggc cctcagtctc aactacacga tcggctccgt ggccagcgcc
    13981 attctcctgg gaggcaccga tgactgagca cacgccgccc ggcgccgggc ccgtgctcga
    14041 aacgggctcc ctggcgcccg tcggccgccg cgtcctgctg gagtccccgc ccggcgccga
    14101 ccacacgcgg gcggtccggg aggtctggga gcgacacggc ttccacgtca cgcacgacga
    14161 gagcgcgcac atgacccagc ccccggacgt gtactgcgtc gtggccatcg gcaacgaagc
    14221 actcggcgcc cggccctcac ctccgttgcg ccgcccccac gtggcccggg tcctgaaggc
    14281 catggcccga cggggcgagg gccgcgccgt cctggtcacc gacacgggcc cgcacgtcca
    14341 cgacgacgcg gagcccgagg ccgccgcaca gcgggccgcc gaccacgcgt ggtggcagca
    14401 cctggccaag cactgcgcga gccggggcgt gctcgccaac acggtgcgcg tcggctacac
    14461 cccgttcctc gggcacgagc tgaccgacga ggcggcgggt gaactgctgc gccacctggt
    14521 cacccgccgc cccgtcgcac cggaggaact ggcggcggca ctgcggctgc tggcctcgcg
    14581 cggcttcggc aacgtcgcgg gcgagacgct gccgctggac ggcggactcg acgcgagcat
    14641 cgtgcccatg ccttcggcac gcccaccgcg aatggacgcg tccgccgccg aaggtgacgg
    14701 cgccgcggtg cccgacccgt tccggctgac cggacgtgtg gtcctggtca ccggcgccag
    14761 cagcgggatc ggggcgagta tcgctcggga gtgcgcggca cgcggcgccg atgtcgtcct
    14821 ggccgcgcgc cgccgcccgg agctggagaa gctcgccgcc gaggtccgcg aactgggccg
    14881 cacggcctgg gtgttgaccg ccgacctgtc ggatccggcg cgggccgccg acctcgtgca
    14941 cgaggcgtgg gagcgtgccg gaggcgtcga cgcgctcgcc tacggcgcgg gcgccgtctc
    15001 cttcgacggc tccggtgaca actccgccaa ccgacagcag ttgctggccc tcaactcgct
    15061 gtcgtacgcg ggtatgtgtg acgcgctgct cgaacactgg gtggctgcgg gccgaagcgg
    15121 ggccgtggcc gccgtctcct cgctggccgc ggtgagcgcg ccggtggcga acctggcgag
    15181 ctacgggctc agcaaggcgg cgaccgcgca gttcaccacc cacttcgcga cctcggcggc
    15241 ccggcacaag gtgcgggcca acagcgtgct tccgggtttc gtccgcaccc cgatgacgga
    15301 cgtcaccaac cccgcgttcc tggaggccac caaccggctc gtgccgaccg gccggatgag
    15361 cgaggcgaca gaggtcgcgg cgctcgtctg ctacctgatc agccccgccg ctgccgggct
    15421 gaccggcacc cagctgcgcg tcgacggcgg cggtcactgc ctggccggac tgccgaacct
    15481 ggccccaccc gagcacaccc ttcgaggaag gaacccggct gtgacgccct gcgtaccacg
    15541 cccccgcccc gccgtgccgg aaggggacca caggtgaccg aggacaggcc cctcaagggc
    15601 aaggtggcgc tggtcgccgg cgcctcgtcc ggcatcgggg cgagcatcgc ccgcgcgctg
    15661 gcggcggccg gcgcctctgt cgccctcgtc gcccgccgca aggaccaact ggcctgcgtc
    15721 gagcgcgacg tggccgggca cgaggtgccc gccgtcacgc tcatcgccga cctgtcggcc
    15781 gacggcgtgc ccaaggagac ggtgaccgcc gccgagcggg ccctcggccc cgtcgacatc
    15841 ctggtgaaca acgccgccct ggctcgcacc ggacccatcc acgacaccaa cccccgccac
    15901 tggcggcagg ccttccacct caatctggac gtccccttcc tgctggcccg cacggtgctc
    15961 cccgggatgc gcgagcgcgg ccacggctgg atcgtcaaca tcagctcgga gggcagtctc
    16021 ctacaggccg actggtcggc cccgtactcc atcaccaaac gcgccctgaa cgcgctgacc
    16081 gcgcaaatcg acctggagaa ccggcacttg ggggtccgcg ccatcgccgt gctgcccggc
    16141 tgggtgcgca cggacctggc gcaggacccc gagtcgctgg gggtgggtgt cacggatctg
    16201 ctggacccct cggacatcgc cgatgtcgtg ctgtgggcca tcacccgccc gcccgctgtc
    16261 agcatcggcc cgctgatacc ggtacgcccc gtcagcagga gtgcccagac cttggtcaac
    16321 tgggagcagt acctgcggac gctgcgccat tacgacgcct ccggcggtca catggtcgac
    16381 gtgcccggga tccctgaatg acgggcccca cgacgtcagc ggccacggcg gcgcgggatc
    16441 tcgacgtggc ggccgaccgc ctcgtcgaga tcctcccgcc gggggacgca cgggtaccgg
    16501 acgccgagca ctgcgtcacg ggcgcgctgc tcgccgcccg cgccgaggcc catcccgacc
    16561 gcgtgtacgc cgtcttcgag gacggcaccc actggacgta cgggcaggcc tacgacgacg
    16621 cgcgcaccac cgccgccgcc ctgtaccggc tgggcgtgcg tcagggcgac accgtgctgt
    16681 gctggctgcc caacggcctg gacgcgctgc gcgtctggta cggcgtcaat ctcctcggcg
    16741 ccgtccacgt ccctgtcaac accgcctatc ggggcgcgct cctggaacac gtactggaca
    16801 actccggggc ccgggtcctt gtggtgcacg cgctgctcgt cgagcggctc cagcacatcg
    16861 gcgacagccg cctccaggag gtcgtcgtcc tcggcggcgg accggacgcg ccctggccgg
    16921 acgccctgcc cggtgccccg cgcgtgcacg gtcccgcggc gctgcggggc ctgccggagg
    16981 acttcgtccc gcccgagcgg ccggtcgcgc cctgggacac catggcggtg atctacacct
    17041 cgggcaccac cggcccgtcc aagggcgtcc tggtctccta cgtccatcac tactcgacgg
    17101 tgaccgcgct cctcgacgac gacatcggcg aggacgaccg gtatctgctc aacctgccgc
    17161 tgtgccacgg cggcggtacc gaagtcgcct actgcatgct cctgttcggg ggctcgatcg
    17221 tcgtcaccga gaacttccgc accggcgagt tctgggacgt ggtgcgccgc cacggggtga
    17281 ccatgtgcac cctgctcggc gccatggtcg acttcctgct cggtctggcc ccccggccgg
    17341 acgaggccga acacccgctg cgggccgcgt gcgtgatacc gctgacgcgc caggccctgg
    17401 acttcggccg ccgcttcggc gtggacgtct acaccgggtt caacatgtcc gagacctcgg
    17461 cgccgctggt gtcaccgctc aatccgcagc gcacgggcag ctgcgggcgg ccgcggccgg
    17521 gggtgcagtg ccgggtggtc gacgcgaacg gcatcgacgt acccgacggc agcgtgggcg
    17581 agctggtgct gcgcgccgac cggccgtggt cgctgttcca cggctaccac gccatgccgg
    17641 aggccaccgc gggggcatgg cggcacggct ggttccgcac cggggacgcc gtggtgcgtg
    17701 agcccggcgg cgactacttc ttcgtggacc gcatcaagga cgccatccgg cgccgcggcg
    17761 agaacgtgtc ctcgatggag gtcgaagccg agttgctgag ccatcccgcc gtggcgttcg
    17821 ccgccgccgt ggcggtgccc agcgacttcg ccgaggacga gatactcgcc gccctcgtgc
    17881 tccggcccgg ggcccgtttc gaaccggagg agttcatcgg gtacctgcgg cctcgcatgg
    17941 cgcacttcat ggtgccgcgc tatctgcgtg tcctgtccga gcttcccgtg acggacacgg
    18001 gcaaggtccg caaggagacg ctgcgcgccc agggcgtcac ccccgacacc tgggaccgcg
    18061 tggcggccgg gatcgaggtc acccgtgacc gcatccgctg agccggccgc ccccgcgcac
    18121 cgtgtcgtcg acgtctgcgc gctgtccctg gaccgcgagt gctggcggac gtacttccgc
    18181 gggctcggcg cggtggcgcc ggcgtacctg cgcgccttcg gccggcacgc gaccgcggtc
    18241 ttcggcgccg attacccgcg cttccgtgcc cgcctagacg ccggggacca ggacggtgcc
    18301 gtcgacctgc tcgtgtcggg tcagcccgaa cgcgtcgact ccgacgcgct gttgaagacc
    18361 atggacgaca acggcgtcgt ccaccagatc ctgatgagct gcggcggcgc caccgccgac
    18421 ggcgacgacg tcaacagccg ggtcgccgcc gtcgccgcca aggcgcccga ccggctccgg
    18481 gcctgggcgg gcattgacct gaccgacccg ggccgtgccg tcgccgagct ggaacgctgc
    18541 catcttctcg gtatgcgcgg cttcgcggtg accccgttct ggcagggcgt cgacccgcgc
    18601 gacaccgcgt acgacccggt ctaccgcagg gcacgagagc tgggcatgcc gttgtggctg
    18661 cacaccgggc accacttctc gcggcacgcg gccgagttgt gccatccccg caacgtcgac
    18721 tggatcgccc tgcgtcaccc cggcctgccg atcgtcgcgg ggcacgccgc ctggccctgg
    18781 acccttgagc tgatctccat cgcccagcgg caccgccacg tctacctcga catctcctcc
    18841 caccgaccgc agtggatggc ccgccccgga tcgggctggg aatccctgct cctgtacggc
    18901 accacggtgc tgcgcgaccg ggtcctgttc ggctcggcga cctgggtcaa cgccgatccg
    18961 gtcgccgcgc tcgcccggca ggtcgccgcc ctggatctcg gcgacgaggt cacggacctc
    19021 tggctgtacg gcaacgcggc ccgcctgctc ggactcggcc ccggctgacg ccggtgcgcg
    19081 cgccccagca cagaaccagc acgtatccag cagagagcac gtaatcagca gagagcacct
    19141 atccagcaga gaaagggacc catcgtgatt gaccccgccg actacgccct gtggaacagc
    19201 ggcgtgccgc gcccgtacct caaggcgctg tcccgcgacg acctgctcac cgagggcgac
    19261 ggcgtgcgcg tccgtgactc cggtggccgc tggtacctgg acggccgctc cgggctgtgg
    19321 aacgtgacgc tcggctacgg caacacccgc gtcaaggagg ccatcaagca gcaggtggac
    19381 cggctgccgt tcgccaacag ctacggctac ggacgtcccg cgcaggtcac cgtggactgc
    19441 gccgaggccc tcgtccgtca tctgcccgag ggcatcaacc acgtccggtt cgccagcaac
    19501 ggggcccagg cggtggagat ggccctccag ctgtcgcgct tcctgcggct gcgggccggg
    19561 cagcccgagc gcatggccgt gttcgccatg tgggacggct tccacgggca ggggccgggc
    19621 gccggcatgg tgaccggtgt cccctacctg caccaccaga ccgggccgat gctccccgag
    19681 gtgcaccacg ctcccggccc gttctcggcg ggcgcgacgc agggcgtcag cgacatggaa
    19741 cggctgatca ccgagttcgg ccccgagcgg gtgaccgcgg tgatcgtgga gcccgtcgtc
    19801 ggcgagggcg gccacatcct gtcccccgag tacctcggct ccctgggccg gttctgccgt
    19861 cagcacgaca tccatctgat cttcgacgag gtcgtcaccg gcatgggccg ggtcggcgac
    19921 ttcacccgcg ccggccaact gcccgatgtc acccccgaca tcatcaccct gggcaagggc
    19981 atcacctcgg ggtacgtgcc gatgtcggcc gtcgccatcc acgaccgcct ctacgagcag
    20041 ctgcacgagc gcaccacggg cgacaccgcg ctcagcgtcg gctcgaccaa cgacggccac
    20101 gcggtggccg ctgcggcggc gctcgcggtg atcggggcgc tcaccgagga cggcgtgctg
    20161 gagaacgtac gccgccgtga ggctgatctc ctctccgccc tgggcaagct ccaggcccag
    20221 caccccgagc tgagggcctt ccgcgctctc ggcctgttct gcggcctgga gctcggcgag
    20281 cccggcggtc cgtcgtggtc cccgggcaag gtgaaccagc tgcgcatgac cttggagagc
    20341 cgaggcgtgc tcagctccag cctgcgtgtc gtaccgaatc tgatgctcat gccgccgctg
    20401 gtcatcaccg aggacgacgt ggcggagata gccgatgcgc tcgacggcgc gctcaccgat
    20461 gtgaagtcgg gtcggcgccc cgagtccggg ttcgccaagg ccatgggatg actcgtcagg
    20521 gccacgggac ggcaacgcgt tttctccacg tgatggaagg tgagtgacga catgtccaat
    20581 gcgcacaccg atcgcaagac cagcaagcag tggcaggaag aggcggcgga ggagtgggac
    20641 cggtacgccg acatctggga cagctggacc cccgatgaca gccgggacga tgccgaggag
    20701 gccgcggact tcctcgcggg cctcgccaag ggcggcaccg ccctggagct ggggatcggg
    20761 acgggccgcg tagccctgcc gctcgcgcag cgcggcgtgc gggtggccgg tatcgacgcc
    20821 tcgccgaaga tgctgctgaa gctcaaggag aagccgggcg gggaccggat cgaggtcttc
    20881 gagggcaact tcgccgatgt cgacgtcaag gaggactacg acgtcatctt catcgccctc
    20941 gccaccctgt tcgtcctgcc cgaccaggac gagcaggccc gctgcctggc caacagtgcc
    21001 aagcggctca agccgggcgg gcggctcgtc gtccagaaca tcgtgccgga catgacgtac
    21061 taccagcgcg ggcggcagaa cgactacggg atgaccgagc cgttccgtat ctcgggccgg
    21121 ctggccgggc acccgcggct cgcctggttc gagatgaacc acgtcgaccc gacgacgcag
    21181 atggtcaagc gcacggacgt catcatgagc gagaagggca accgcatcat cgcggcgacc
    21241 atgcggttcg tgtggccctc ggagcaggac ctgatggccc ggctgggcgg cctgacgctg
    21301 gaggaccgct ggggaggctg gcgcaaggag cccttccact acgacagcag ggacgcggtg
    21361 tccgtctacc gcaagcagtg accgtccggc gccggacgtg accgaggccg ggggcggcga
    21421 ccagccgctc ccggcctcgg ccgcaccgag cgtgcccgaa cctgcccgta caggcatcgg
    21481 gggtactcga acgggccgca ggacgagtac ttccagggcg taggtagccg gtggaaccgt
    21541 cactacgctg atggttccga cccccgtcaa gtgcaccgat tcagggtggg cagaagcaat
    21601 gagcgaagag ttcgggcagg atcgtccggc cgaagcgggc agcgggagcg gcacggacgt
    21661 gctcgtcgag cgccgcggcc ccgtgctcgt gatccaactg aaccggccgc gcgtacgcaa
    21721 cgcgctgacc cgcgccatgg ccgaacggct cgccgccgcc ttcacggaac tggatgcccg
    21781 agcggagctg cgtctcggcg tcctgaccgg caccccgccg gcgttctgct ccggcatgga
    21841 cctcggggcc ttcgcccgcg gggagcgcgc ctccctgccg gggcgtggct tcggcggtct
    21901 gacggagcag ccgccgagca agccgctgat cgccgccgtg gagggtgcgg cggtcggcgg
    21961 tggtttcgag atggtgctcg cctgcgacat ggtggtggcg gcggacgacg cggtgttcgg
    22021 gctgcccgag ctgcgccgag ggctggtggc cgcggccggc ggactgctgc ggctgccgcg
    22081 cgcgatcgcg ccggccgtgg cgatggagat ggcactgacc ggcgaaccga tcgatgcgca
    22141 gcgggccttc gcgctgggtc ttgtcaaccg tgtggtggcc ccggggacgg cgctgacggc
    22201 cgcctgcgag ctggcggaga agatcgccgc gcatgcggac cacgccgtcc tcgcgagcaa
    22261 gggggtcctc gctcgggtgc gcgacgggga gttggcggac gagtaccggt cgcaccgcga
    22321 gctgctgtcg gggatcctcg actcccccgg cgcgcgggca ggtgcgcgtg agttcgtccg
    22381 ggaacgtccg ggcggaccgc gatgacgtgc acggacgggg accggatggt caaccccggg
    22441 ccccggtggt caccccggtc ggagaggagt acttacggaa cagttcacgt cggccgctga
    22501 cgcccagttt ccgcagggcg ctactgactt gattctttat ggtctgggag gccagggaga
    22561 gttcgctggc gatttcctcg ttggtatagc ggcgcagtac gaggctcagg acctgctctt
    22621 cccggcgggt gatggcgggc agcccgtcgg gcatgacgct gcgcacgtcc acgtgttcgc
    22681 gttcgttctt gccaagtatc cacatgcgtt ggccgttgta cgtgcgcacc accgcgtcca
    22741 cgagttccga actgcccacg ctcttgtgca ggaagctgtc ggcccccgcc gatatggcgg
    22801 agacgacggc cccgggcgag gtgtctccgg tgaagacgac gacccggggc gcgtcctcca
    22861 tcgccttcac ccgttggcag agatcggcac cgctggtcgc gccgtccagt tccagttcga
    22921 gtacgacgac acccgggcag gacgttgtga cggcattcca cgcctcgtca ctcgtggcgg
    22981 cctccgccgt ccacgccact ctcgtgtcga gcagtgacga cagcgcgtac ctgaccacgg
    23041 ggtggcgatc gacgacgagt acacctaacg cttgcatggg gactcctcac gcagtgagtg
    23101 cagcggatgg gtagtcaggt ctgcaatgct ccgagatgtg cctgcgccac gctccggatg
    23161 ccgccccgag ggcggcgcgt cgagacgagc ggtatcagac gagctgggtc agtcgctgcg
    23221 tgggcccgtg gcctcccgca cggctgactc cagggggcgg gctggtcagg ccggcactcg
    23281 gagtcattca atgtcacgta atcaatcgtg ggacaacacc ccgttggaca ttccgaaaac
    23341 ggaatcagtc gctcctagac accccgttgg acattccgcg ttcggattcg gtcgttcctc
    23401 cttgccccga ccgcggatga cagacgactg actagag
//
