BGC0001154: cacibiocin B biosynthetic gene cluster from Catenulispora acidiphila DSM 44928
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Location: 3,103,844 - 3,129,235 nt. (total: 25,392 nt).
This entry is originally from NCBI GenBank CP001700.1.

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General information about the BGC

MIBiG accession | BGC0001154
Short description | cacibiocin B biosynthetic gene cluster from Catenulispora acidiphila DSM 44928
Status | Quality: questionable The quality level of this entry. Status: active The status of this entry. Completeness: complete Whether the entry covers everything needed for the pathway producing the compound(s)

Remarks "genes involved in the biosynthesis of the pyrrole-\n2,5-dicarboxylic acid moiety are not yet identified"
Biosynthetic class(es)

- other (other)

Loci
CP001700.1
3108359 - 3124919
via Heterologous expression
Compounds

- cacibiocin B

Species Catenulispora acidiphila DSM 44928 [taxonomy]
References

- [1] Complete genome sequence of Catenulispora acidiphila type strain (ID 139908). Copeland A et al., Stand Genomic Sci (2009) PMID:21304647
- [2] New aminocoumarins from the rare actinomycete Catenulispora acidiphila DSM 44928: identification, structure elucidation, and heterologous production. Zettler J et al., Chembiochem (2014) PMID:24554531

Chemical products information
cacibiocin B Evidence:
Copy SMILES
C15H8Cl2N2O7
Chemical database entries
NPAtlas
List of genes involved in compound(s) production

Identifiers | Position | Product | Functions | Evidence | Extra
--- | --- | --- | --- | --- | ---
Caci_2714 ACU71629.1 | 3108359 - 3109678 (-) | sodium/hydrogen exchanger |  |  | copy AA seq copy Nt seq
Caci_2715 ACU71630.1 | 3109685 - 3110959 (-) | FAD dependent oxidoreductase |  |  | copy AA seq copy Nt seq
Caci_2716 ACU71631.1 | 3110956 - 3112239 (-) | Pyridoxal-5'-phosphate-dependent protein beta subunit |  |  | copy AA seq copy Nt seq
Caci_2717 ACU71632.1 | 3112206 - 3113840 (-) | amide synthetase | Scaffold biosynthesis |  | copy AA seq copy Nt seq
Caci_2718 ACU71633.1 | 3113844 - 3114626 (-) | b-ketotyrosyl-reductase | Scaffold biosynthesis |  | copy AA seq copy Nt seq
Caci_2719 ACU71634.1 | 3114623 - 3115117 (-) | conserved hypothetical protein |  |  | copy AA seq copy Nt seq
Caci_2720 ACU71635.1 | 3115114 - 3115881 (-) | b-ketotyrosyl-reductase | Scaffold biosynthesis |  | copy AA seq copy Nt seq
Caci_2721 ACU71636.1 | 3115878 - 3116192 (-) | MbtH-like protein | Scaffold biosynthesis |  | copy AA seq copy Nt seq
Caci_2722 ACU71637.1 | 3116235 - 3117458 (-) | cytochrome P450 | Scaffold biosynthesis |  | copy AA seq copy Nt seq
Caci_2723 ACU71638.1 | 3117460 - 3119235 (-) | peptide synthetase-like protein | Scaffold biosynthesis |  | copy AA seq copy Nt seq
Caci_2724 ACU71639.1 | 3119401 - 3120921 (+) | tryptophan halogenase | Tailoring |  | copy AA seq copy Nt seq
Caci_2725 ACU71640.1 | 3121002 - 3122297 (-) | transcriptional regulator, LuxR family | Regulation |  | copy AA seq copy Nt seq
Caci_2726 ACU71641.1 | 3122566 - 3124068 (-) | drug resistance transporter, EmrB/QacA subfamily | Resistance/immunity |  | copy AA seq copy Nt seq
Caci_2727 ACU71642.1 | 3124125 - 3124919 (+) | transcriptional regulator, TetR family | Regulation |  | copy AA seq copy Nt seq

Biosynthesis information

No biosynthesis information available for this record.

Annotation changelog

#### Entry version: 2

Date
Changes
Submitters
Reviewers
2019-10-16
Migrated from v1.4

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

2019-10-16
Updated compound(s) information (NPAtlas curation)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

#### Entry version: 1

Date
Changes
Submitters
Reviewers
2015-06-12
Submitted

- (ID: 6BNBMTTKZLI3ZE3JTCJWEZIV)

- (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

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