BGC0001157: bottromycin A2 biosynthetic gene cluster from Streptomyces scabiei 87.22
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Location: 6,304,534 - 6,321,700 nt. (total: 17,167 nt).
This entry is originally from NCBI GenBank FN554889.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001157
Short description bottromycin A2 biosynthetic gene cluster from Streptomyces scabiei 87.22
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • RiPP (Bottromycin)
Loci NCBI GenBank: FN554889.1
Compounds
  • bottromycin A2
Species Streptomyces scabiei 87.22 [taxonomy]
References
Chemical products information
bottromycin A2
Copy SMILES
C42H62N8O7S1
Chemical database entries
PubCHEM
ChemSpider
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SCAB_56591
  • CBG72685.1
 6304534 - 6305976 (-) putative cytosolic aminopeptidase
  • Tailoring (Hydrolysis)
Sequence-based prediction
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  • SCAB_56601
  • CBG72686.1
 6305981 - 6306553 (-) hypothetical protein
  • Regulation
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  • SCAB_56611
  • CBG72687.1
 6306673 - 6308631 (-) Radical SAM methyltransferase
  • Tailoring (Methylation)
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  • SCAB_56621
  • CBG72688.1
 6308639 - 6309775 (-) P450
  • Tailoring (Oxidation)
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  • SCAB_56631
  • CBG72689.1
 6309855 - 6311276 (-) Putative hydrolase
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  • SCAB_56641
  • CBG72690.1
 6311273 - 6312088 (-) Putative hydrolase
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  • SCAB_56651
  • CBG72691.1
 6312123 - 6314138 (-) Radical SAM methyltransferase
  • Tailoring (Methylation)
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  • SCAB_56661
  • CBG72692.1
 6314135 - 6315574 (-) YcaO domain protein
  • Tailoring (Heterocyclization)
Sequence-based prediction
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  • SCAB_56671
  • CBG72693.1
 6315426 - 6316682 (-) YcaO domain protein
  • Tailoring (Heterocyclization)
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  • SCAB_56681
  • CBG72694.1
 6316746 - 6316880 (-) Precursor peptide
  • Scaffold biosynthesis
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  • SCAB_56691
  • CBG72695.1
 6317014 - 6318951 (-) Radical SAM methyltransferase
  • Tailoring (Methylation)
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  • SCAB_56701
  • CBG72696.1
 6319368 - 6320207 (+) Methyltransferase
  • Tailoring (Methylation)
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  • SCAB_56711
  • CBG72697.1
 6320390 - 6321700 (+) Major facilitator superfamily protein
  • Transport
Sequence-based prediction
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RiPP-specific information
Subclass Bottromycin
Cyclic? yes
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: YDLZYFWUWQQQNGTRZENZCBP5, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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