Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001158.1:
Cluster 1Polyketide11569
The following clusters are from record BGC0001158.2:
Cluster 2Polyketide11459
The following clusters are from record BGC0001158.3:
Cluster 3Polyketide1981
The following clusters are from record BGC0001158.4:
Cluster 4Polyketide11819
The following clusters are from record BGC0001158.5:
Cluster 5Polyketide12234
The following clusters are from record BGC0001158.6:
Cluster 6Polyketide16060

BGC0001158, bikaverin biosynthetic gene cluster from Botrytis cinerea. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: bikaverin
PubChem ID: 5281730
SMILES string: Copy to clipboard
Molecular formula: C20H14O8
Average molecular mass: 382.324 Da
Molecular activity: Antibacterial, Antifungal

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (cyclic)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
CCH26295.1
Iterative PKS subtype:
Non-reducing
Number of iterations:
9
Other
Thioesterase type:
Unknown
Release / cyclization type:
Unknown

Gene cluster description

bikaverin (BGC0001158). Gene Cluster 1. Biosynthetic class = Polyketide. GenBank HE802545. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production, Sequence-based prediction, Other
MIxS-compliance:Unknown
Contact for this cluster:Muriel Viaud (INRA)

Literature references

1. Schumacher J et al. (2013 TI) A functional bikaverin biosynthesis gene cluster in rare strains of Botrytis cinerea is positively controlled by VELVET. PLoS One 8(1):e53729. doi: 10.1371/journal.pone.0053729. Epub 2013 Jan 7.

BGC0001158, bikaverin biosynthetic gene cluster from Botrytis cinerea. Locus 2. Full MIBiG entry.

Chemical compounds

Compound: bikaverin
PubChem ID: 5281730
SMILES string: Copy to clipboard
Molecular formula: C20H14O8
Average molecular mass: 382.324 Da
Molecular activity: Antibacterial, Antifungal

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (cyclic)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
CCH26295.1
Iterative PKS subtype:
Non-reducing
Number of iterations:
9
Other
Thioesterase type:
Unknown
Release / cyclization type:
Unknown

Gene cluster description

bikaverin (BGC0001158). Gene Cluster 2. Biosynthetic class = Polyketide. GenBank HE802546. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production, Sequence-based prediction, Other
MIxS-compliance:Unknown
Contact for this cluster:Muriel Viaud (INRA)

Literature references

1. Schumacher J et al. (2013 TI) A functional bikaverin biosynthesis gene cluster in rare strains of Botrytis cinerea is positively controlled by VELVET. PLoS One 8(1):e53729. doi: 10.1371/journal.pone.0053729. Epub 2013 Jan 7.

BGC0001158, bikaverin biosynthetic gene cluster from Botrytis cinerea. Locus 3. Full MIBiG entry.

Chemical compounds

Compound: bikaverin
PubChem ID: 5281730
SMILES string: Copy to clipboard
Molecular formula: C20H14O8
Average molecular mass: 382.324 Da
Molecular activity: Antibacterial, Antifungal

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (cyclic)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
CCH26295.1
Iterative PKS subtype:
Non-reducing
Number of iterations:
9
Other
Thioesterase type:
Unknown
Release / cyclization type:
Unknown

Gene cluster description

bikaverin (BGC0001158). Gene Cluster 3. Biosynthetic class = Polyketide. GenBank HE802547. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production, Sequence-based prediction, Other
MIxS-compliance:Unknown
Contact for this cluster:Muriel Viaud (INRA)

Literature references

1. Schumacher J et al. (2013 TI) A functional bikaverin biosynthesis gene cluster in rare strains of Botrytis cinerea is positively controlled by VELVET. PLoS One 8(1):e53729. doi: 10.1371/journal.pone.0053729. Epub 2013 Jan 7.

BGC0001158, bikaverin biosynthetic gene cluster from Botrytis cinerea. Locus 4. Full MIBiG entry.

Chemical compounds

Compound: bikaverin
PubChem ID: 5281730
SMILES string: Copy to clipboard
Molecular formula: C20H14O8
Average molecular mass: 382.324 Da
Molecular activity: Antibacterial, Antifungal

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (cyclic)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
CCH26295.1
Iterative PKS subtype:
Non-reducing
Number of iterations:
9
Other
Thioesterase type:
Unknown
Release / cyclization type:
Unknown

Gene cluster description

bikaverin (BGC0001158). Gene Cluster 4. Biosynthetic class = Polyketide. GenBank HE802548. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production, Sequence-based prediction, Other
MIxS-compliance:Unknown
Contact for this cluster:Muriel Viaud (INRA)

Literature references

1. Schumacher J et al. (2013 TI) A functional bikaverin biosynthesis gene cluster in rare strains of Botrytis cinerea is positively controlled by VELVET. PLoS One 8(1):e53729. doi: 10.1371/journal.pone.0053729. Epub 2013 Jan 7.

BGC0001158, bikaverin biosynthetic gene cluster from Botrytis cinerea. Locus 5. Full MIBiG entry.

Chemical compounds

Compound: bikaverin
PubChem ID: 5281730
SMILES string: Copy to clipboard
Molecular formula: C20H14O8
Average molecular mass: 382.324 Da
Molecular activity: Antibacterial, Antifungal

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (cyclic)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
CCH26295.1
Iterative PKS subtype:
Non-reducing
Number of iterations:
9
Other
Thioesterase type:
Unknown
Release / cyclization type:
Unknown

Gene cluster description

bikaverin (BGC0001158). Gene Cluster 5. Biosynthetic class = Polyketide. GenBank HE802549. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production, Sequence-based prediction, Other
MIxS-compliance:Unknown
Contact for this cluster:Muriel Viaud (INRA)

Literature references

1. Schumacher J et al. (2013 TI) A functional bikaverin biosynthesis gene cluster in rare strains of Botrytis cinerea is positively controlled by VELVET. PLoS One 8(1):e53729. doi: 10.1371/journal.pone.0053729. Epub 2013 Jan 7.

BGC0001158, bikaverin biosynthetic gene cluster from Botrytis cinerea. Locus 6. Full MIBiG entry.

Chemical compounds

Compound: bikaverin
PubChem ID: 5281730
SMILES string: Copy to clipboard
Molecular formula: C20H14O8
Average molecular mass: 382.324 Da
Molecular activity: Antibacterial, Antifungal

Class-specific details

Biosynthetic class(es):
Polyketide
Polyketide subclass:
Other (cyclic)
Polyketide synthase subclass:
Iterative type I
Starter unit:
Acetyl-CoA
Polyketide synthase / ketosynthase-encoding genes:
CCH26295.1
Iterative PKS subtype:
Non-reducing
Number of iterations:
9
Other
Thioesterase type:
Unknown
Release / cyclization type:
Unknown

Gene cluster description

bikaverin (BGC0001158). Gene Cluster 6. Biosynthetic class = Polyketide. GenBank HE802550. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Domain annotation

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Gene expression correlated with compound production, Sequence-based prediction, Other
MIxS-compliance:Unknown
Contact for this cluster:Muriel Viaud (INRA)

Literature references

1. Schumacher J et al. (2013 TI) A functional bikaverin biosynthesis gene cluster in rare strains of Botrytis cinerea is positively controlled by VELVET. PLoS One 8(1):e53729. doi: 10.1371/journal.pone.0053729. Epub 2013 Jan 7.