LOCUS       BGC0001161              9161 bp    DNA     linear   BCT 13-JUL-2015
DEFINITION  Moorea bouillonii PNG5-198 fatty acyl ACP ligase and polyketide
            synthase genes, complete cds.
ACCESSION   BGC0001161
VERSION     BGC0001161
KEYWORDS    .
SOURCE      Moorena bouillonii PNG
  ORGANISM  Moorena bouillonii PNG
            Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
            Oscillatoriales; Oscillatoriaceae; Moorena.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 15:01:33
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..2454
                     /NRPS_PKS="Domain: AMP-binding (39-516). E-value: 7.2e-87.
                     Score: 283.4. Matches aSDomain:
                     nrpspksdomains_AHH34187.1_AMP-binding.1"
                     /NRPS_PKS="Domain: ACP (660-728). E-value: 2.9e-21. Score:
                     67.5. Matches aSDomain: nrpspksdomains_AHH34187.1_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     390.3; E-value: 1.9e-118)"
                     /gene_kind="biosynthetic"
                     /note="part of OLS pathway"
                     /product="fatty acyl ACP ligase"
                     /protein_id="AHH34187.1"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-103, bitscore:
                     332.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5e-17, bitscore:
                     49.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDDLAVKIRHAGMKDSLDQMSENIPKFSTLVDLLRYRAIHQPDQ
                     IIYTFLLNGETPDRYLTHQQLDNHAQAIASELLHQNAKGERALLLYPPGLEFITAFFGC
                     LYAGVLAVPAYPPRSNQNLSRLEAIVADAQAKFALTTTPLLEKIETQLAENPASASLKW
                     LATDKTRGVGIPPHKQPTNHESDWQHPDCNEKTLAFLQYTSGSTGKPKGVMVSHGNLLY
                     NSALINQCFQDTPQSRGLSWLPAYHDMGLIGGILQPLYVGLPIILMAPVDFLRKPYRWL
                     KAISKYQVTTSGAPNFAYELCVHKITPKQLETLDLSSWQMAFTGAEPVRASTLERFAQK
                     FAPCGFHREAFYPCYGMAETTLLVTGGLKDQPPVVREFEGEALEQNRVVPLPENRLNQS
                     NGQSNGQSNGQSNGQSNGNVPTRILVGCGRTWLNEKIAIAHPQSLTQVEAGAVGEIWVK
                     GPSVAQGYWNQPEVTEKTFNAYLADTGLGPWLRTGDLGFIQDGELFVTGRLKDLIIIRG
                     RNHYPQDIELTAEKSHPALRPAYGAAFSVEVEEAEQLVIVQEVSRNYLRKLDVDQVVEA
                     IRSAISQEYQLQVYAVLLLKTNSIPKTSSGKVQRHACRAGFLNNSLTVVGQWSLAQQPT
                     IAPTKPEKELTTNTIGLQQSSKSIQKWIIDWLARETKLPPQSINISKSFADYGLDSVTA
                     VELADDLEEWLGVPLSPTLAYDYPNIESLAQYLAKVSQQSNSNQGDSPRKIEPRVSSAG
                     SEMQQLWEAQFQNLDRFTSIPFYRSPVTVKSIASSGDQEVDQLLAELEMLSEAQIQEIL
                     GKPIK"
     source          1..9161
                     /collected_by="W. Gerwick"
                     /collection_date="19-May-2005"
                     /country="Papua New Guinea"
                     /db_xref="taxon:568701"
                     /identified_by="Niclas Engene"
                     /lat_lon="5.40 S 146.32 E"
                     /mol_type="genomic DNA"
                     /organism="Moorena bouillonii PNG"
                     /specimen_voucher="PNG:5-198"
                     /strain="PNG 5-198"
     protocluster    1..9161
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2465:9161]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2466..9161
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     protocluster    1..9161
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:2454]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      1..2454
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     cand_cluster    1..9161
                     /SMILES="NC(C)C(=O)CC(O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="neighbouring"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..9161
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001161"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..9161
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        118..1548
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AHH34187.1_AMP-binding.1"
                     /evalue="7.20E-87"
                     /label="AHH34187.1_AMP-binding.1"
                     /locus_tag="AHH34187.1"
                     /protein_end="516"
                     /protein_start="39"
                     /score="283.4"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="IHQPDQIIYTFLLNGETPDRYLTHQQLDNHAQAIASELLHQNAKG
                     ERALLLYPPGLEFITAFFGCLYAGVLAVPAYPPRSNQNLSRLEAIVADAQAKFALTTTP
                     LLEKIETQLAENPASASLKWLATDKTRGVGIPPHKQPTNHESDWQHPDCNEKTLAFLQY
                     TSGSTGKPKGVMVSHGNLLYNSALINQCFQDTPQSRGLSWLPAYHDMGLIGGILQPLYV
                     GLPIILMAPVDFLRKPYRWLKAISKYQVTTSGAPNFAYELCVHKITPKQLETLDLSSWQ
                     MAFTGAEPVRASTLERFAQKFAPCGFHREAFYPCYGMAETTLLVTGGLKDQPPVVREFE
                     GEALEQNRVVPLPENRLNQSNGQSNGQSNGQSNGQSNGNVPTRILVGCGRTWLNEKIAI
                     AHPQSLTQVEAGAVGEIWVKGPSVAQGYWNQPEVTEKTFNAYLADTGLGPWLRTGDLGF
                     IQDGELFVTGRLKDLIIIR"
     aSModule        118..2184
                     /complete
                     /domains="nrpspksdomains_AHH34187.1_AMP-binding.1"
                     /domains="nrpspksdomains_AHH34187.1_ACP.1"
                     /locus_tags="AHH34187.1"
                     /monomer_pairings="Ala -> Ala"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       592..651
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34187.1_0001"
                     /evalue="6.70E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="AHH34187.1"
                     /protein_end="217"
                     /protein_start="197"
                     /score="30.9"
                     /tool="antismash"
                     /translation="AFLQYTSGSTGKPKGVMVSH"
     CDS_motif       1345..1431
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34187.1_0002"
                     /evalue="2.80E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="AHH34187.1"
                     /protein_end="477"
                     /protein_start="448"
                     /score="42.0"
                     /tool="antismash"
                     /translation="AGAVGEIWVKGPSVAQGYWNQPEVTEKTF"
     CDS_motif       1516..1578
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34187.1_0003"
                     /evalue="3.50E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="AHH34187.1"
                     /protein_end="526"
                     /protein_start="505"
                     /score="16.5"
                     /tool="antismash"
                     /translation="TGRLKDLIIIRGRNHYPQDIE"
     aSDomain        1981..2184
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AHH34187.1_ACP.1"
                     /evalue="2.90E-21"
                     /label="AHH34187.1_ACP.1"
                     /locus_tag="AHH34187.1"
                     /protein_end="728"
                     /protein_start="660"
                     /score="67.5"
                     /tool="antismash"
                     /translation="KWIIDWLARETKLPPQSINISKSFADYGLDSVTAVELADDLEEWL
                     GVPLSPTLAYDYPNIESLAQYLA"
     CDS             2466..9161
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (39-488). E-value:
                     8.6e-186. Score: 609.8. Matches aSDomain:
                     nrpspksdomains_AHH34186.1_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (597-896). E-value: 2.3e-110.
                     Score: 360.5. Matches aSDomain:
                     nrpspksdomains_AHH34186.1_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1234-1412). E-value: 9e-64.
                     Score: 206.6. Matches aSDomain:
                     nrpspksdomains_AHH34186.1_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1502-1579). E-value: 5.8e-15.
                     Score: 47.3. Matches aSDomain:
                     nrpspksdomains_AHH34186.1_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 282.4; E-value:
                     1.1e-85)"
                     /gene_kind="biosynthetic"
                     /note="part of OLS pathway"
                     /product="polyketide synthase"
                     /protein_id="AHH34186.1"
                     /sec_met_domain="PKS_KS (E-value: 3.1e-187, bitscore:
                     609.8, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 8.2e-112, bitscore:
                     360.5, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 9.3e-60, bitscore:
                     188.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.9e-16, bitscore:
                     45.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 5.1e-24, bitscore: 72.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRSMLPVDDIAKRIANLSPEKRALLELQLQKRKGLKEPIAIIGI
                     GCRFPGASSPKSFWQLLKNGVDAITEVPPERWDIERFYDKDPTAPGKMYCRYGGFLAHV
                     DKFDPEFFGIAPREATYIDPQQRLLLEVIWEALEDAGQVPSKLSGSQTGVFVGISTHDY
                     GQLLLQSPEVVDTYTNTGVASTMAANRISYLLNFKGPSLTVDTACSSSLVAVHLACQSI
                     WNGESTVAIAGGVNLMLTPVVTVGLSKLTALSPDGRCKAFDSRANGFVRGEGAGVIVVK
                     PLSKALIDKDPIYAVIRGSAVNQDGRTNGLTAPNRDAQEAVLVSAYQHAGISPSDVQYV
                     ETHGTGTLLGDPIEAMALGNVLKRDRKAVPKEHRSDNNSDNNSDNYGALSTHPTNKPVA
                     IGSVKSNIGHLEAAAGIASLIKVALSLKHQERLPSLHFQEPNPHIPFDELPLRVQQQRE
                     PWPWDVIPPFAGVSSFGFGGTNAHVVLQGAPELTKATSNDRDENDQDQNYHLFTLSAKT
                     ATALQTLGKRYIDFIGSEPSSTLADICLTSNKGRSHFNYRLALLVKSTDQLQQQLTKLT
                     ESETISEKIAQNSPTPPEIVFLFTGQGSQYSGMGRQLYETQPIFRATLDQCAEILQSYL
                     EQPLLDVLYPEILSDNSDNSTLNQTAYTQPALFALEYSLAQLWRSWGIEPTVVMGHSVG
                     EYVAATVAGVFSLEDGLKLIAERARLMQQLPAGGEMAVILTNEQQVTEAIQSLSDKVSI
                     AAINGPENIVISGESQAVQTVIARLRSQKVKSLKLPVSHAFHSHLMQPMVGDFAQVLSE
                     ISLHPPQIEIISNLTGKLATAEIATTEYWCDHVRGSVKFYQSMETLYQEGYQLCVEVGP
                     KPSLLGMGKACLPKGKLTAIPSLRPGKPDSRQMLESLASLYKHGASVDWGRFHQHNPRR
                     LVSLPTYPFERQRYWLDTTSVKPLSPISYGQLSTPSYGDWLYQIAWRPKDVDSSDISTD
                     ISKSSTTWLIFADKEGFGERFGETLIQQLAEKCQKVLLISPGSSYEQLQPNHYQINPAQ
                     PQHFQRLLAQEVESLNATSVIVVHMWSLDTPALDRLQTFPLDATLENGCGSVLHLLQGL
                     VKAELAQPPRLWLVTEGTQPVALEKKGKTKKSLQIAQSPLWGLGAVIAQEHPEIWGGII
                     DLEPSQDSALNNEQHYQEQSLMLLNQILQPQGENQIALRDGQAYVPRLIHQQQQSQPPA
                     LPLQLKPDSTYLITGGLGSLGLKVAEWMVDKGARYLVLVGRSQPNPRASEIIGKLEEQG
                     VMVVLEQVDVSQEAQVRDCLNRIQVSLPPLKGIIHGAGVLEDGVLLHQDWAKFARVMKP
                     KVEGAWNLHRLTQDIALELFVLFSSATSILGTPGQGNYSAANGFLDSLSHYRQGQGASA
                     LSINWGPWAEMGLAAGVGKRMAMLGIEPIQAPQGLQILEQLLAQDGAQVGVLPVEWSKL
                     KERLPVELPLFLSEVITTETLPPQGDRENDNSGIFDQLLGSTTTQREELLNDYLKQQIA
                     KALGISREISGSSNLMDLGADSLMIVEVLNACKKDLKITLYPREFYERPTITALAEYLA
                     LEMERLHQPQPTQTSLTTTSLSDIKNWANPWAWNNSERNFTKPTQRNRSMVFLLCSPRS
                     GSTLLRVMLAGHRDLFCPPELHLLPFESMAERNQSLGSTHLGEGLARAFMEIMNLDAEA
                     STTLVEEITQQDWSIQKVYGRLQELTGKRTLVDKSPTYAGSLETLRHAEDLFEEAKYIH
                     LVRHPYAVIDSFVKNRMDKIFGIDEVNPYWLAEEVWTTCNRNILDFCEEIAPSNHHLVY
                     YEELVKQPALVMARLCEFLDIPFDEAVLEPYQGQRMTDGVHPQSLPVDDPNFRNHNQID
                     SALGEVWRQIQLPRPLGNFAEEVATRLDYQLPLLLEPSAQPANLGQKATLPEQLEPMQE
                     SYLDVRGLQLCLCSWGPVDGDLILCIHGVLEHGAAWEEIARPLASMGYRVVAPDQRGHG
                     LSQHVGMGGSYQLIDYLGDLDAIAFGAAEPNPNPLTDQPFILVGHSMGAVVAATFASVR
                     PEKVKSLVLLEPVLPGEGKEDETAQQLATHLDYLASPPQHQVFEDIQAAANRLRRLTPN
                     LSEELALKHAERLTEPGEGGVRWRWDPRLQIRTGIGLSGTAFNRDKYTQLLNQIKAPTT
                     LVYGNNSNFNRAEDLALQQAAIPHAKTVTLSGGHNLHVDAPDAIVAIIANQKLNLKNSK
                     VTR"
     aSDomain        2583..3929
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AHH34186.1_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="8.60E-186"
                     /label="AHH34186.1_PKS_KS.1"
                     /locus_tag="AHH34186.1"
                     /protein_end="488"
                     /protein_start="39"
                     /score="609.8"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="IAIIGIGCRFPGASSPKSFWQLLKNGVDAITEVPPERWDIERFYD
                     KDPTAPGKMYCRYGGFLAHVDKFDPEFFGIAPREATYIDPQQRLLLEVIWEALEDAGQV
                     PSKLSGSQTGVFVGISTHDYGQLLLQSPEVVDTYTNTGVASTMAANRISYLLNFKGPSL
                     TVDTACSSSLVAVHLACQSIWNGESTVAIAGGVNLMLTPVVTVGLSKLTALSPDGRCKA
                     FDSRANGFVRGEGAGVIVVKPLSKALIDKDPIYAVIRGSAVNQDGRTNGLTAPNRDAQE
                     AVLVSAYQHAGISPSDVQYVETHGTGTLLGDPIEAMALGNVLKRDRKAVPKEHRSDNNS
                     DNNSDNYGALSTHPTNKPVAIGSVKSNIGHLEAAAGIASLIKVALSLKHQERLPSLHFQ
                     EPNPHIPFDELPLRVQQQREPWPWDVIPPFAGVSSFGFGGTNAHVVLQGA"
     aSModule        2583..7202
                     /complete
                     /domains="nrpspksdomains_AHH34186.1_PKS_KS.1"
                     /domains="nrpspksdomains_AHH34186.1_PKS_AT.1"
                     /domains="nrpspksdomains_AHH34186.1_PKS_KR.1"
                     /domains="nrpspksdomains_AHH34186.1_PKS_PP.1"
                     /locus_tags="AHH34186.1"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       3060..3107
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34186.1_0001"
                     /evalue="5.60E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="AHH34186.1"
                     /protein_end="214"
                     /protein_start="198"
                     /score="21.4"
                     /tool="antismash"
                     /translation="GPSLTVDTACSSSLVA"
     CDS_motif       3249..3287
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34186.1_0002"
                     /evalue="6.20E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="AHH34186.1"
                     /protein_end="274"
                     /protein_start="261"
                     /score="12.9"
                     /tool="antismash"
                     /translation="FDSRANGFVRGEG"
     CDS_motif       3480..3527
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34186.1_0003"
                     /evalue="1.10E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="AHH34186.1"
                     /protein_end="354"
                     /protein_start="338"
                     /score="11.5"
                     /tool="antismash"
                     /translation="YVETHGTGTLLGDPIE"
     CDS_motif       3666..3710
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34186.1_0004"
                     /evalue="3.90E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="AHH34186.1"
                     /protein_end="415"
                     /protein_start="400"
                     /score="12.7"
                     /tool="antismash"
                     /translation="GSVKSNIGHLEAAAG"
     aSDomain        4257..5153
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AHH34186.1_PKS_AT.1"
                     /evalue="2.30E-110"
                     /label="AHH34186.1_PKS_AT.1"
                     /locus_tag="AHH34186.1"
                     /protein_end="896"
                     /protein_start="597"
                     /score="360.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYSGMGRQLYETQPIFRATLDQCAEILQSYLEQPLLDV
                     LYPEILSDNSDNSTLNQTAYTQPALFALEYSLAQLWRSWGIEPTVVMGHSVGEYVAATV
                     AGVFSLEDGLKLIAERARLMQQLPAGGEMAVILTNEQQVTEAIQSLSDKVSIAAINGPE
                     NIVISGESQAVQTVIARLRSQKVKSLKLPVSHAFHSHLMQPMVGDFAQVLSEISLHPPQ
                     IEIISNLTGKLATAEIATTEYWCDHVRGSVKFYQSMETLYQEGYQLCVEVGPKPSLLGM
                     GKACLPKGKLTAIPSLRP"
     CDS_motif       4260..4307
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34186.1_0005"
                     /evalue="3.70E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="AHH34186.1"
                     /protein_end="614"
                     /protein_start="598"
                     /score="19.3"
                     /tool="antismash"
                     /translation="FTGQGSQYSGMGRQLY"
     CDS_motif       4449..4505
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34186.1_0006"
                     /evalue="3.00E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="AHH34186.1"
                     /protein_end="680"
                     /protein_start="661"
                     /score="17.0"
                     /tool="antismash"
                     /translation="YTQPALFALEYSLAQLWRS"
     CDS_motif       4509..4631
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34186.1_0007"
                     /evalue="9.40E-28"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="AHH34186.1"
                     /protein_end="722"
                     /protein_start="681"
                     /score="88.7"
                     /tool="antismash"
                     /translation="GIEPTVVMGHSVGEYVAATVAGVFSLEDGLKLIAERARLMQ"
     CDS_motif       4725..4763
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34186.1_0008"
                     /evalue="2.00E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="AHH34186.1"
                     /protein_end="766"
                     /protein_start="753"
                     /score="14.5"
                     /tool="antismash"
                     /translation="AAINGPENIVISG"
     CDS_motif       6168..6266
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34186.1_0009"
                     /evalue="7.50E-18"
                     /label="PKSI-KR_m1"
                     /locus_tag="AHH34186.1"
                     /protein_end="1267"
                     /protein_start="1234"
                     /score="57.0"
                     /tool="antismash"
                     /translation="TYLITGGLGSLGLKVAEWMVDKGARYLVLVGRS"
     aSDomain        6168..6701
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AHH34186.1_PKS_KR.1"
                     /evalue="9.00E-64"
                     /label="AHH34186.1_PKS_KR.1"
                     /locus_tag="AHH34186.1"
                     /protein_end="1412"
                     /protein_start="1234"
                     /score="206.6"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="TYLITGGLGSLGLKVAEWMVDKGARYLVLVGRSQPNPRASEIIGK
                     LEEQGVMVVLEQVDVSQEAQVRDCLNRIQVSLPPLKGIIHGAGVLEDGVLLHQDWAKFA
                     RVMKPKVEGAWNLHRLTQDIALELFVLFSSATSILGTPGQGNYSAANGFLDSLSHYRQG
                     QGASALSINWGPWAE"
     CDS_motif       6492..6521
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34186.1_0010"
                     /evalue="2.20E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="AHH34186.1"
                     /protein_end="1352"
                     /protein_start="1342"
                     /score="11.4"
                     /tool="antismash"
                     /translation="PKVEGAWNLH"
     CDS_motif       6543..6653
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34186.1_0011"
                     /evalue="8.90E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="AHH34186.1"
                     /protein_end="1396"
                     /protein_start="1359"
                     /score="63.3"
                     /tool="antismash"
                     /translation="LELFVLFSSATSILGTPGQGNYSAANGFLDSLSHYRQ"
     aSDomain        6972..7202
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AHH34186.1_PKS_PP.1"
                     /evalue="5.80E-15"
                     /label="AHH34186.1_PKS_PP.1"
                     /locus_tag="AHH34186.1"
                     /protein_end="1579"
                     /protein_start="1502"
                     /score="47.3"
                     /tool="antismash"
                     /translation="TTTQREELLNDYLKQQIAKALGISREISGSSNLMDLGADSLMIVE
                     VLNACKKDLKITLYPREFYERPTITALAEYLA"
     CDS_motif       8550..8597
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AHH34186.1_0012"
                     /evalue="8.90E-05"
                     /label="NRPS-te1"
                     /locus_tag="AHH34186.1"
                     /protein_end="2044"
                     /protein_start="2028"
                     /score="15.1"
                     /tool="antismash"
                     /translation="DQPFILVGHSMGAVVA"
ORIGIN
        1 atggacgacg atttggctgt gaaaataagg catgcaggta tgaaagacag tttagatcag
       61 atgagcgaga atataccaaa attttctacc ttagtagacc tgctacgtta ccgagcaata
      121 caccagccgg atcagattat ctatacattt ttactgaacg gggaaacccc agaccgctac
      181 ctaacccatc aacagttaga caaccacgcc caagcgatcg catccgagct tctacaccaa
      241 aacgcaaaag gggagcgagc tttgctactc tatccacccg gtttagagtt tatcacagct
      301 ttcttcggct gtttgtatgc aggagtgtta gccgttcccg cttatccccc ccgctccaat
      361 caaaatttgt ccaggctaga ggcaattgtg gcagatgctc aggccaaatt tgccctgact
      421 actacccctc tattagagaa aatagagact cagctagctg aaaatcccgc cagtgctagc
      481 ttaaagtggc tggctactga caagacgagg ggtgtgggga tacctcccca caagcaacct
      541 acgaaccatg aatcggattg gcagcacccg gactgtaacg aaaagaccct ggcttttcta
      601 cagtacacct ctggctcaac gggtaaaccc aaaggagtaa tggttagcca cgggaatttg
      661 ttatataact cagctttgat taatcagtgt ttccaagata caccccaaag cagaggattg
      721 tcttggttac ctgcttacca tgatatggga ctgattggcg gcatcctaca acccctttat
      781 gttggtcttc ccatcatcct gatggctcca gtagatttcc tccgcaagcc ttaccgctgg
      841 ctaaaagcaa tttccaaata ccaggtgact accagtggtg ctccgaattt tgcctatgag
      901 ctgtgtgtac ataaaattac ccctaagcaa ttagaaaccc ttgacctgag cagctggcaa
      961 atggccttta ccggtgctga gccggttcga gcctcaacat tagagcgatt tgctcaaaaa
     1021 tttgcccctt gtggtttcca tcgggaagca ttttacccct gttatggcat ggcagaaacc
     1081 acattattag tcactggagg cttgaaagac caacctccag tggtaaggga atttgaaggg
     1141 gaagctcttg aacaaaatcg agtggttccc ctgccagaaa atcgtctcaa tcagtctaat
     1201 ggtcagtcta atggtcagtc taatggtcag tctaatggtc agtctaatgg taatgtgccg
     1261 actcgaatcc tggttgggtg tggccggact tggttaaatg aaaaaattgc gatcgcacac
     1321 ccccaatccc taacccaagt tgaagccggt gccgtcggag agatttgggt aaaaggtcca
     1381 agtgttgctc aaggctattg gaatcaacca gaggtgacgg aaaaaacctt taatgcctat
     1441 ctagctgata ctggtttagg accatggctg cgtactggtg atttaggatt tatccaggat
     1501 ggcgagttgt ttgtaacagg tcgtctgaag gatttaatta ttatccgggg tcgcaaccat
     1561 tatccccaag atatagaatt gacggcggaa aagagtcatc cagctcttcg ccctgcctat
     1621 ggcgcagctt tttctgtgga agtggaagag gctgagcaat tggtgattgt ccaagaagtt
     1681 tccaggaatt acctgcggaa actagatgtc gatcaagtgg ttgaagcaat ccggagtgcc
     1741 atctcccaag aataccagct tcaagtctat gctgtgttat tgctcaagac caatagtatt
     1801 cccaagacat ccagtggcaa agtacagcgc catgcttgtc gagctggatt tctaaacaat
     1861 agcttgacag ttgtagggca atggagtttg gcacaacagc caaccattgc cccaactaaa
     1921 ccagaaaaag aactcaccac taatactatc ggccttcagc aaagctccaa atcaattcaa
     1981 aagtggataa tagattggct agcgcgagaa acaaaacttc ctccccagtc tattaacatc
     2041 agcaagtctt ttgctgatta tggtctagat tcagtaacag cagttgaact agctgatgat
     2101 ctcgaagaat ggttaggggt gcctctgtct cctacactgg cttatgatta tcccaatatc
     2161 gagtcccttg cccaatatct ggcgaaagta agtcaacaaa gcaactcaaa ccagggggac
     2221 agcccaagaa aaatcgaacc gagagtttcg agtgcaggta gtgagatgca acaattatgg
     2281 gaggcacagt tccagaatct ggatcggttc acctcgattc ccttttatcg ttcacccgta
     2341 acggttaaat cgattgcctc cagtggtgat caagaggtag accaactctt agctgagttg
     2401 gaaatgcttt cagaagcaca aatccaagaa attctgggaa aacccatcaa ataattccta
     2461 gatctatgtt tcgatctatg ttgccagtgg atgatattgc taagcggatt gccaatctct
     2521 cccccgaaaa acgcgccctt cttgaattgc agctgcaaaa gaggaaaggc ttaaaagaac
     2581 ctattgctat tatcgggatt ggctgccgct ttccaggtgc ctcttcccca aaatcattct
     2641 ggcaactgct caaaaatggt gtcgatgcta ttactgaagt gccaccagag cgttgggata
     2701 tcgagagatt ttacgacaag gaccccacag caccaggcaa aatgtattgt cgttatggtg
     2761 gtttcctggc gcatgttgat aaattcgatc cagaattctt tggcattgct cctcgggaag
     2821 ctacctatat cgacccccag cagcgactac tgttggaagt aatttgggaa gcactagagg
     2881 atgcaggcca agtgcctagt aaactcagtg gtagccaaac gggggtcttt gttggcattt
     2941 ctactcatga ttatggtcag ctgcttctcc aaagtccaga ggtggtggat acctatacca
     3001 atactggtgt agcttccact atggcagcta atcgcatttc ctacctactg aatttcaaag
     3061 ggccaagtct aacggttgat acggcttgct cctcatccct agtcgctgtt catttggctt
     3121 gtcagagtat ctggaatggt gagtcaaccg tagccatagc agggggagtg aatttgatgc
     3181 taaccccagt ggtgacggtt gggttgagta agttaacggc tttatctccc gatggtcgct
     3241 gtaaagcatt tgattcccgt gccaatggct ttgtcagggg cgagggcgct ggggtgatag
     3301 tagtaaagcc cctatccaaa gccctgatcg ataaagatcc aatttatgct gtgattcgag
     3361 gcagtgcggt gaaccaagat gggcgcacta atgggctaac tgctcccaat cgagacgctc
     3421 aggaagctgt tctagtctcg gcctaccagc acgcgggcat ttcaccttca gatgtgcagt
     3481 atgtagaaac ccatggcacc ggaaccctac tgggagaccc gattgaagcg atggccttgg
     3541 gaaatgtcct aaaacgcgat cgcaaagcgg ttccaaagga acatcgctct gacaataact
     3601 ctgataataa ctctgataac tacggtgcgt tatcaaccca tcctaccaac aagcctgttg
     3661 cgattggctc ggtcaaatct aatattggtc atctagaagc agctgctggt attgctagtt
     3721 taatcaaagt tgccctatcc ctcaagcacc aagaacgttt acccagcctc catttccagg
     3781 agccaaatcc ccacattccc tttgatgaac tgcccctgcg agtacagcag caacgggagc
     3841 cttggccatg ggatgttatt cccccatttg ctggtgtaag ttctttcggt tttggaggaa
     3901 ccaatgctca tgtggtgcta caaggagcgc cagagttgac aaaagcgaca agtaatgata
     3961 gagacgaaaa cgatcaagac caaaactatc atctatttac cttgtctgcc aaaacagcaa
     4021 ccgccctgca aaccctagga aagcgataca tagacttcat aggatctgag ccatcaagca
     4081 cactagcaga tatttgtttg accagcaata aagggcgatc gcattttaac tatcgtctag
     4141 ccctcctagt taaatccact gaccagttgc agcaacaact gaccaagttg acagaaagcg
     4201 aaaccatttc ggaaaaaata gcacaaaata gccctactcc ccccgaaatc gttttccttt
     4261 tcaccggtca aggctctcag tatagtggta tgggaaggca actttacgaa acccaaccaa
     4321 tctttcgggc tactctcgac caatgcgccg aaattctgca atcctattta gaacagccgt
     4381 tactggatgt cctgtatcca gaaatcttga gcgacaacag tgacaactcc acattaaatc
     4441 aaacggccta cacccaacca gcattatttg ctctagaata ctccctggct cagttatggc
     4501 ggtcttgggg aatcgaacca accgtggtta tgggtcatag tgttggggaa tatgtggcag
     4561 caactgtagc aggagtcttt agcttagaag atgggctcaa gctgattgcc gaaagagcgc
     4621 gtttgatgca acagttgcca gcagggggtg aaatggcagt cattttgacc aatgagcagc
     4681 aggtcactga ggcaattcaa tccctatccg acaaagtctc aatcgctgcc attaacggtc
     4741 cggaaaatat tgtgatttct ggggaaagtc aggcggttca aaccgtgata gcccgactac
     4801 gctctcaaaa ggtcaaatca ctaaagttgc cagtctccca tgccttccat tctcacctaa
     4861 tgcaaccaat ggtgggagat tttgctcagg tattatcgga aatatcctta catcccccac
     4921 aaatagagat aatttcgaat ttaactggaa aattagccac tgctgagata gctacgaccg
     4981 agtattggtg tgaccatgtg cgtgggtccg tgaaattcta ccagagcatg gaaacccttt
     5041 atcaagaggg ttatcaactg tgtgtggaag taggaccgaa gcctagccta ttgggaatgg
     5101 gcaaagcgtg cttaccgaaa ggaaagctca cagctatacc aagtttgcgc ccaggaaaac
     5161 cagatagtcg gcaaatgctg gaaagtttgg caagcctata taaacatggc gcatcagtag
     5221 actggggaag attccatcag cataaccccc gtcgcctagt ttccctaccc acttatccgt
     5281 ttgaacggca acggtattgg ctagatacca cttcagtaaa accattatcc ccgatttcct
     5341 atggccaact atcgactccc tcctatgggg attggttgta tcaaatagca tggcgaccta
     5401 aggatgtaga ttcatctgat atatctactg atatatctaa atctagtaca acttggttga
     5461 tttttgctga taaagagggc tttggagaaa gatttggaga aacattaatt caacagctgg
     5521 cagaaaaatg ccaaaaggtt ttgctaattt cccctggctc aagttatgaa caattacaac
     5581 caaaccatta tcaaattaac ccagcgcaac cgcaacactt tcagcgtctg ttagctcaag
     5641 aagtcgaatc cctaaacgca acatctgtga ttgtggttca tatgtggagt ttagatactc
     5701 ccgcactgga ccgattgcaa acatttcccc tagacgccac cttagaaaac ggttgtggta
     5761 gtgtcttgca tctgctgcaa gggttagtca aagcagaatt agctcaaccc cctcgtctgt
     5821 ggttagttac cgagggcaca caacccgtag cattagagaa aaaaggtaag acgaaaaaat
     5881 ccctacagat tgcccagtct cccctatggg gtttaggtgc agttattgcc caagaacatc
     5941 cagaaatctg gggagggata atagacctag aaccaagtca agactcagca ctgaacaatg
     6001 agcagcacta ccaagagcaa tcattaatgc tgctcaacca gatattacag ccacagggag
     6061 aaaaccaaat tgctttgagg gatggacaag cctatgtgcc tcgcctgatt catcaacagc
     6121 aacagtctca accccccgct ttaccattac agctaaaacc agatagcacc tacttaatta
     6181 ccggtggttt ggggtcactg gggttaaagg tagctgaatg gatggtcgat aagggggcaa
     6241 ggtatttagt attagtagga cgaagccaac caaatcctag ggcgtcagaa ataattggga
     6301 aattagaaga acaaggtgtg atggtagtcc tggagcaggt ggatgtatcc caggaagcac
     6361 aagttagaga ctgtctcaac agaattcagg tttccctacc ccccctcaaa ggaattatcc
     6421 atggtgcagg ggtgctggag gatggggtgc tgctgcacca agattgggca aaatttgcca
     6481 gggtgatgaa accgaaagtt gagggagcct ggaatttaca caggttgact caggatatag
     6541 ccctagagtt atttgtacta ttttcttccg ccacctctat cctaggtacc cctggtcaag
     6601 gaaactattc cgcagctaac ggatttttag atagcctcag ccattatcga caagggcaag
     6661 gtgcgagcgc tttaagtatt aattgggggc cttgggctga gatgggttta gccgctggcg
     6721 tcggtaaacg gatggcaatg ctgggaatag agccgattca agcaccacag ggattacaga
     6781 tactcgaaca acttctggca caagatgggg ctcaggtggg ggtattaccg gtggagtggt
     6841 caaagttaaa agaacgacta ccggtagagt taccgttatt cctatcagag gtaatcacaa
     6901 cagaaacact accgcctcag ggggatcggg aaaacgacaa ttctgggatt tttgatcaac
     6961 tgctcggtag tacaacaacc caacgggaag agttattaaa cgattacctt aagcaacaga
     7021 ttgctaaggc tttagggata agtcgcgaaa tctcagggtc gagcaacctg atggatttgg
     7081 gtgctgattc cttgatgatt gtagaagtac tcaatgcctg taagaaagac ctgaagataa
     7141 cgctttatcc tagggagttt tatgagcgac caacgattac agctctagct gagtacttgg
     7201 ctttggagat ggaacggctt catcagcccc agccaaccca aacctcattg accactacta
     7261 gtctctcaga tattaagaat tgggctaatc cttgggcatg gaacaatagc gaacgaaatt
     7321 ttaccaaacc cacccagcgc aatcggagca tggtgttttt gctgtgtagc cctcggtcag
     7381 gctccacctt actgcgggtg atgctagctg gtcatcggga tttattctgt ccaccagaat
     7441 tacacctatt gccctttgaa agcatggccg agcgcaatca atccttgggt tcaactcact
     7501 taggagaagg gttagcgcga gctttcatgg aaatcatgaa cctagatgcc gaagcaagta
     7561 caacactggt ggaggagata acccagcaag actggtcaat tcagaaggtt tatggcaggt
     7621 tacaggaact aacgggtaaa cgtactcttg tggataagtc tcctacctat gctggcagtc
     7681 tggaaaccct aaggcacgcg gaagatttat ttgaagaagc caagtatatt catctagtac
     7741 gtcatcccta tgccgtaatt gattccttcg tgaaaaatcg gatggataaa atctttggta
     7801 ttgatgaggt gaacccttat tggctagcag aggaagtttg gacaacctgt aaccgtaata
     7861 tcctagactt ctgcgaggaa attgcaccat ctaatcatca tttagtgtat tacgaggaac
     7921 tagtaaagca acctgctttg gtcatggcaa ggttgtgtga gtttctggat attccttttg
     7981 atgaggcggt tttagaaccc tatcaaggcc agcggatgac ggatggagtt catccccaat
     8041 ccctaccggt agatgacccc aatttccgca accataacca aattgattcg gctttgggag
     8101 aggtttggcg gcaaatccag ttgccccggc ctttggggaa ttttgcggaa gaggtagcga
     8161 cacggttgga ttatcaattg ccgttactgc ttgaaccttc agcccaacca gctaaccttg
     8221 gccaaaaggc cacgctaccc gaacaacttg aaccgatgca ggagtcttat ctagacgtgc
     8281 ggggtttaca gctgtgtctg tgtagttggg gtccagtcga tggagattta atcctatgta
     8341 tccatggtgt tttagaacat ggagcggctt gggaagaaat tgcccgtccc ttagcaagta
     8401 tgggatatcg agtcgttgca cctgaccagc gaggccatgg actttcccag catgtaggta
     8461 tgggagggtc ttatcaatta attgactact taggggattt agatgcgatc gcgtttggcg
     8521 cggcagagcc taacccaaat ccactgacag accagccatt tattctagtc ggtcattcca
     8581 tgggggctgt agttgctgcc acctttgcca gtgttagacc cgaaaaggtc aagtctttag
     8641 tattgctgga gccagtgcta ccaggggaag ggaaggagga tgaaacggct caacagttag
     8701 caactcattt agattatcta gcatccccac cccaacacca agtctttgag gatatccaag
     8761 ctgctgctaa tcgtctgcgc cgcttaaccc ccaacctctc tgaagaatta gctttaaaac
     8821 atgctgagcg acttacggaa cctggtgagg gtggtgtacg ttggcgctgg gatccaagac
     8881 tgcaaattcg tacgggaatt ggtttaagtg gaacagcttt taatcgggat aaatacacac
     8941 agttactgaa tcaaattaaa gctcctacta ctttagttta tggcaataat agtaacttta
     9001 accgagccga agacctagcc ttacaacaag ctgccatacc tcatgctaaa acagtaacac
     9061 tatcaggagg acataacctc catgtcgatg caccagatgc tatagttgca attatcgcca
     9121 accaaaaatt aaatctgaaa aattcaaaag tgacaaggta a
//
