BGC0001166 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001166 (Alternaria jesenskae)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	15,624

BGC0001166 - Region 1 - NRPS

Download region GenBank file

Download region SVG

Location: 1 - 15,624 nt. (total: 15,624 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 15,625
Label		BGC0001166

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001166.1	1.00	NRP	HC-toxin	Alternaria jesenskae
BGC0001833.1	0.28	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001261.1	0.28	NRP	AM-toxin	Alternaria alternata
BGC0001135.1	0.26	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001220.1	0.26	NRP	aculeacin A	Aspergillus japonicus
BGC0001132.1	0.25	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001844.1	0.25	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001758.1	0.24	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001641.1	0.22	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000357.1	0.21	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001166.1	1.00	NRP	HC-toxin	Alternaria jesenskae
BGC0001833.1	0.62	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001261.1	0.61	NRP	AM-toxin	Alternaria alternata
BGC0001135.1	0.60	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001220.1	0.59	NRP	aculeacin A	Aspergillus japonicus
BGC0001132.1	0.59	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001844.1	0.58	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001758.1	0.58	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001641.1	0.55	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000357.1	0.53	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255

Similar known gene clusters

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 15624:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-pro - ala - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

HTS1

Search NORINE for peptide: strict or relaxed

AMP-binding (218..617): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: diavitvlik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1826..2232): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: daggcamvak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2978..3385): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dllffgsvlk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4131..4534): X

NRPSPredictor2: gly, ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvllctgimk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)