BGC0001166: HC-toxin biosynthetic gene cluster from Alternaria jesenskae
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Location: 1 - 15,624 nt. (total: 15,624 nt).
This entry is originally from NCBI GenBank KC862269.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001166
Short description HC-toxin biosynthetic gene cluster from Alternaria jesenskae
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: incomplete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: KC862269.1
Compounds
  • HC-toxin
Species Alternaria jesenskae [taxonomy]
References
Chemical products information
HC-toxin
Copy SMILES
C21H32N4O6
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AGQ43600.1
  • HTS1
 1 - 15624 (+) HC-toxin synthetase
  • Scaffold biosynthesis
Sequence-based prediction
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NRP-specific information
Subclass N/A
Cyclic? yes
Release type
  • Macrolactamization
NRP-synthases
Gene Modules
HTS1
Module 1
Specificity: proline
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: Unknown
Modification domains: Unknown
Module 2
Specificity: alanine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: Unknown
Module 3
Specificity: D-alanine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: Unknown
Module 4
Specificity: 2S-amino-9,10-epoxy-8-oxodecanoic acid
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: Unknown
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: EYZO6ZFFY6I7ZU7RR4A7A64Y, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Updated NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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