Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001167.1:
Cluster 1RiPP19324

BGC0001167, piricyclamide biosynthetic gene cluster from Microcystis aeruginosa. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: Piricyclamide
Molecular activity: Unknown

Class-specific details

Biosynthetic class(es):
RiPP
RiPP subclass:
None (cyclic)
Peptides in this cluster:
AFK79987.1
RiPP core peptide sequence(s): WILLADGTRPKNAP
Leader peptide length: 32
Follower peptide length: 7
Peptidase(s) involved in precursor cleavage: afk79993.1, afk79998.1
Crosslinks in final product:
- None
AFK79996.1
RiPP core peptide sequence(s): TFCDLATKQCYP
Leader peptide length: 32
Follower peptide length: 7
Peptidase(s) involved in precursor cleavage: afk79993.1, afk79998.1
Crosslinks in final product:
3=10 AA (Thioether)
AFK79988.1
RiPP core peptide sequence(s): NEFMQTGSYSGP
Leader peptide length: 32
Follower peptide length: 7
Peptidase(s) involved in precursor cleavage: afk79993.1, afk79998.1

Gene cluster description

piricyclamide (BGC0001167). Gene Cluster 1. Biosynthetic class = RiPP. GenBank JQ951924. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Heterologous expression
MIxS-compliance:Unknown
Contact for this cluster:David Fewer (University of Helsinki)

Literature references

1. Leikoski N et al. (2012 TI) Analysis of an inactive cyanobactin biosynthetic gene cluster leads to discovery of new natural products from strains of the genus Microcystis. PLoS One 7(8):e43002. doi: 10.1371/journal.pone.0043002. Epub 2012 Aug 27.