BGC0001168 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001168 (Streptomyces lividans 1326)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS-like	1	4,582	Livipeptin	NRPS:Type V	100%

BGC0001168 - Region 1 - NRPS-like

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Location: 1 - 4,582 nt. (total: 4,582 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 4,583
Label		BGC0001168

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001168	1.00	NRP	livipeptin	Streptomyces lividans 1326
BGC0002602	0.22	Alkaloid	aspergillic acid	Aspergillus flavus
BGC0001516	0.22	NRP	aspergillic acid	Aspergillus flavus NRRL3357
BGC0001599	0.20	NRP	fragin	Burkholderia cenocepacia H111
BGC0002348	0.20	NRP	aspulvinone E	Aspergillus terreus NIH2624
BGC0002582	0.20	NRP	guanipiperazine A, guanipiperazine B	Streptomyces chrestomyceticus
BGC0001132	0.19	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0002286	0.19	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135	0.19	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001128	0.19	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001168	1.00	NRP	livipeptin	Streptomyces lividans 1326
BGC0002602	0.55	Alkaloid	aspergillic acid	Aspergillus flavus
BGC0001516	0.55	NRP	aspergillic acid	Aspergillus flavus NRRL3357
BGC0001599	0.53	NRP	fragin	Burkholderia cenocepacia H111
BGC0002348	0.52	NRP	aspulvinone E	Aspergillus terreus NIH2624
BGC0002582	0.52	NRP	guanipiperazine A, guanipiperazine B	Streptomyces chrestomyceticus
BGC0001132	0.51	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0002286	0.51	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135	0.50	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001128	0.50	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 4582:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Arg)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

SLI_0883

Search NORINE for peptide: strict or relaxed

AMP-binding (3..391): Arg

nrpys: Arg

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DTEDIGAITK
Nearest Stachelhaus code(s):: Arg DTEDIGAITK (100% 8Å match)
Stachelhaus code match:: 100% (strong)