BGC0001168: Livipeptin biosynthetic gene cluster from Streptomyces lividans 1326
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Location: 891,947 - 896,528 nt. (total: 4,582 nt).
This entry is originally from NCBI GenBank CM001889.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
Operons
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001168
Short description Livipeptin biosynthetic gene cluster from Streptomyces lividans 1326
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type V)
Loci
CM001889.1
891947 - 896528
via Knock-out studies, Heterologous expression, Gene expression correlated with compound production
Compounds
  • Livipeptin
Species Streptomyces lividans 1326 [taxonomy]
References
Chemical products information
Livipeptin [synonyms: 2-acetamido-N-(5-guanidino-1-oxopentan-2-yl)-3-phenylpropanamide] Evidence: Mass spectrometry [1]
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C17H25N5O3
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SLI_0883
  • EOY45602.1
 891947 - 894913 (+) Adenylation and reductase domains containing protein
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    • SLI_0884
    • EOY45603.1
    		 894936 - 895718 (+) Leucyl/Phenylalanil-tRNA-Protein transferase
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      • SLI_0885
      • EOY45604.1
      		 895746 - 896528 (+) N-Acyl transferase
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        Biosynthesis information
        Operons
        Genes Evidence
        SLI_0883, SLI_0884, SLI_0885
        Annotation changelog

        Entry version: next

        Date
        Changes
        Submitters
        Reviewers
        2024-07-31
        MIBiG v4 annotathon
        • (ID: VS2OWCDWMTWO6ITJSKJXQZUA)
        • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 4

        Date
        Changes
        Submitters
        Reviewers
        2022-10-07
        Update chemical activity to schema version 2.11
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 3

        Date
        Changes
        Submitters
        Reviewers
        2022-09-15
        Corrected NRP module activity
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        2022-09-15
        Corrected gene identifiers
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        2022-09-15
        Updated bioactivity data
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        2022-09-15
        Updated NRP substrate specificities
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 2

        Date
        Changes
        Submitters
        Reviewers
        2019-10-16
        Migrated from v1.4
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

        Entry version: 1

        Date
        Changes
        Submitters
        Reviewers
        2015-06-12
        Submitted
        • (ID: YFQE6LBJ4VCTUO2RYKJB5QD7)
        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
        Detailed domain annotation
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