Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001174.1:
Cluster 1RiPP16052

BGC0001174, corynazolicin biosynthetic gene cluster from Corynebacterium urealyticum. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: corynazolicin
SMILES string: Copy to clipboard
Molecular formula: C55H56N18O9S7
Exact molecular mass: 1337.2595 Da ([M+H]+)
Molecular activity: Antibacterial

Class-specific details

Biosynthetic class(es):
RiPP subclass:
LAP (linear)
Peptides in this cluster:
RiPP core peptide sequence(s): RCSCTTIPCCCCCGG
Leader peptide length: 31
Follower peptide length: -1
Peptidase(s) involved in precursor cleavage: cu7111_1587

Gene cluster description

corynazolicin (BGC0001174). Gene Cluster 1. Biosynthetic class = RiPP. GenBank CP004085, positions 1876183-1882234. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Enzymatic assays, Sequence-based prediction
Contact for this cluster:Doug Mitchell (University of Illinois at Urbana-Champaign)

Literature references

1. Molohon KJ et al. (2011) Structure determination and interception of biosynthetic intermediates for the plantazolicin class of highly discriminating antibiotics. ACS Chem Biol 6(12):1307-13. doi: 10.1021/cb200339d. Epub 2011 Oct