BGC0001177: mensacaricin biosynthetic gene cluster from Streptomyces bottropensis
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Location: 1 - 36,742 nt. (total: 36,742 nt).
This entry is originally from NCBI GenBank KJ437437.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001177
Short description mensacaricin biosynthetic gene cluster from Streptomyces bottropensis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Type II)
Loci
KJ437437.1
via Heterologous expression
Compounds
  • mensacaricin
Species Streptomyces bottropensis [taxonomy]
References
Chemical products information
mensacaricin Evidence:
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C21H24O9
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AHL46681.1
  • msnO1
 10041 - 10787 (-) ketoreductase
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    • AHL46682.1
    • msnO2
    		 10963 - 12018 (-) luciferase-like monooxygenase
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      • AHL46683.1
      • msnO3
      		 12015 - 12536 (-) flavin reductase
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        • AHL46684.1
        • msnH5
        		 12564 - 13667 (-) hypothetical protein
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          • AHL46685.1
          • msnK2
          		 13727 - 14932 (-) ketosynthase
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            • AHL46686.1
            • msnK1
            		 15028 - 16293 (-) ketosynthase
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              • AHL46687.1
              • msnH6
              		 16365 - 17210 (-) hypothetical protein
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                • AHL46688.1
                • msnO4
                		 17207 - 18286 (-) luciferase-like monooxygenase
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                  • AHL46689.1
                  • msnO5
                  		 18310 - 18615 (-) monooxygenase
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                    • AHL46690.1
                    • msnC1
                    		 18644 - 19891 (-) putative bifunctional cyclase/dehydratase
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                      • AHL46691.1
                      • msnO6
                      		 19881 - 20198 (-) monooxygenase
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                        • AHL46692.1
                        • msnO7
                        		 20409 - 20723 (+) monooxygenase
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                          • AHL46693.1
                          • msnC2
                          		 20720 - 21643 (+) putative cyclase
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                            • AHL46694.1
                            • msnO8
                            		 21678 - 22682 (+) luciferase-like monooxygenase
                            • Activation / processing
                            • Knock-out Activity assay
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                            • AHL46695.1
                            • msnO9
                            		 22735 - 23706 (+) putative NADPH:quinone oxidoreductase
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                              • AHL46696.1
                              • msnO10
                              		 23762 - 24544 (+) ketoreductase
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                                • AHL46697.1
                                • msnK3
                                		 24585 - 24881 (+) acyl carrier protein
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                                  • AHL46698.1
                                  • msnO11
                                  		 24874 - 25659 (+) ketoreductase
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                                    • AHL46699.1
                                    • msnC3
                                    		 25720 - 26664 (+) putative bifunctional cyclase/dehydratase
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                                      • AHL46700.1
                                      • msnR1
                                      		 27058 - 27909 (+) SARP regulatory protein
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                                        • AHL46701.1
                                        • msnH7
                                        		 27944 - 28855 (+) hypothetical protein
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                                          • AHL46702.1
                                          • msnH8
                                          		 28852 - 29187 (+) hypothetical protein
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                                            • AHL46703.1
                                            • msnR2
                                            		 29338 - 32181 (-) regulatory protein
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                                              • AHL46704.1
                                              • msnM1
                                              		 32650 - 34113 (-) adenosylhomocysteinase
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                                                • AHL46705.1
                                                • msnM2
                                                		 34091 - 34996 (-) N5,N10-methylene etrahydrofolate reductase
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                                                  • AHL46706.1
                                                  • msnM3
                                                  		 34993 - >36741 (-) methionine synthase
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                                                    Biosynthesis information
                                                    Annotation changelog

                                                    Entry version: 3

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2022-10-07
                                                    Update chemical activity to schema version 2.11
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 2

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2019-10-16
                                                    Migrated from v1.4
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                    Entry version: 1

                                                    Date
                                                    Changes
                                                    Submitters
                                                    Reviewers
                                                    2015-06-12
                                                    Submitted
                                                    • (ID: LPHAMZXQ3BT6INJWOLKUYGWU)
                                                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                    Detailed domain annotation
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