Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001184.1:
Cluster 1Other17298

BGC0001184, bacilysin biosynthetic gene cluster from Bacillus amyloliquefaciens. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: bacilysin
PubChem ID: 160175
SMILES string: Copy to clipboard
Molecular formula: C12H18N2O5
Average molecular mass: 270.285 Da
Molecular activity: Antibacterial

Class-specific details

Biosynthetic class(es):
Other
Other biosynthetic class:
None

Gene cluster description

bacilysin (BGC0001184). Gene Cluster 1. Biosynthetic class = Other. GenBank CP000560, positions 3593877-3599784. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Knock-out studies, Gene expression correlated with compound production, Sequence-based prediction
MIxS-compliance:Unknown
Contact for this cluster:Rainer Borriss (Humboldt University)

Literature references

1. Chen XH et al. (2009) Difficidin and bacilysin produced by plant-associated Bacillus amyloliquefaciens are efficient in controlling fire blight disease. J Biotechnol 140(1-2):38-44. doi: 10.1016/j.jbiotec.2008.10.015.
2. Wu L et al. (2014) Bacilysin from Bacillus amyloliquefaciens FZB42 has specific bactericidal activity against harmful algal bloom species. Appl Environ Microbiol 80(24):7512-20. doi: 10.1128/AEM.02605-14. Epub
3. Wu L et al. (2015) Difficidin and bacilysin from Bacillus amyloliquefaciens FZB42 have antibacterial activity against Xanthomonas oryzae rice pathogens. Sci Rep 5:12975. doi: 10.1038/srep12975.