BGC0001187: xenolozoyenone biosynthetic gene cluster from Glarea lozoyensis
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Location: 1 - 12,562 nt. (total: 12,562 nt).
This entry is originally from NCBI GenBank KM603664.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Polyketide
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001187
Short description xenolozoyenone biosynthetic gene cluster from Glarea lozoyensis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: incomplete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP (Other lipopeptide)
  • Polyketide (Other)
Loci NCBI GenBank: KM603664.1
Compounds
  • xenolozoyenone
Species Glarea lozoyensis [taxonomy]
References
Chemical products information
xenolozoyenone
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C17H23N1O4
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AKL78824.1
  • glpks3
 499 - 9519 (+) GLPKS3
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  • AKL78825.1
  • glnrps7
 9546 - 12209 (+) GLNRPS7
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Polyketide-specific information
Subclass Other
Starter unit Propionyl-CoA
Cyclic? yes
Polyketide-synthases
Genes Properties Modules
glpks3
+
glpks3 		Synthase subclass: Iterative type I
Iterative PKS type: Highly reducing, Unknown
Iteration counts: 6
Module 1
Specificity: Propionyl-CoA
Evidence for specificity: Structure-based inference
Genes: glpks3
Core domains: Ketosynthase, Acyltransferase, Dehydratase, Enoylreductase, Ketoreductase, Thiolation (ACP/PCP), Condensation
KR-domain stereochemistry: Unknown
Non-canonical activity:
  • Iterated
Evidence for non-canonical activity:
  • Structure-based inference
NRP-specific information
Subclass Other lipopeptide
Cyclic? yes
Lipid moiety (4E,6E,8E)-3-oxopentadeca-4,6,8-trienoic acid
Thioesterase genes
  • glnrps7 (Unknown)
NRP-synthases
Gene Modules
glnrps7
Module 2
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
Condensation domain type: Unknown
Annotation changelog
MIBiG version Submitter Notes
1.1
  • Hidden contributor (ID: T6QCSVEAKBFCHEG52RTY4VCK, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected NRP module activity
  • Changed amino acid substrates to lower case
Detailed domain annotation
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