BGC0001193: thiolutin biosynthetic gene cluster from Saccharothrix algeriensis
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Location: 1 - 41,334 nt. (total: 41,334 nt).
This entry is originally from NCBI GenBank KM114209.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001193
Short description thiolutin biosynthetic gene cluster from Saccharothrix algeriensis
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: KM114209.1
Compounds
  • thiolutin
Species Saccharothrix algeriensis [taxonomy]
References
Chemical products information
thiolutin
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C8H8N2O2S2
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AJI44167.1
 72 - 5129 (+) long-chain-fatty-acid-CoA ligase
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  • AJI44168.1
 5138 - 6523 (+) hypothetical protein
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  • AJI44169.1
 6516 - 7544 (+) 2-keto-3-deoxy-D-arabino-heptulosonate-7
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  • AJI44170.1
 7727 - 9277 (+) hypothetical protein
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  • AJI44171.1
 9461 - 10681 (-) cytochrome P450 hydroxylase
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  • AJI44172.1
 10714 - 11886 (-) ferredoxin reductase
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  • AJI44173.1
 11901 - 12107 (-) ferredoxin
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  • AJI44191.1
 12859 - 13524 (-) hypothetical protein
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  • AJI44174.1
  • dtpR2
 14314 - 15279 (+) streptomycin biosynthesis operon regulator
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  • AJI44175.1
  • dtpA
 15332 - 15913 (-) phosphopantothenoylcysteine decarboxylase
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  • AJI44176.1
  • dtpB
 16250 - 19384 (+) nonribosomal peptide synthetase
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  • AJI44177.1
  • dtpC
 19381 - 20931 (+) glucose-methanol-choline oxidoreductase
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  • AJI44178.1
 20937 - 21683 (+) hypothetical protein
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  • AJI44179.1
 21685 - 22827 (+) hypothetical protein
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  • AJI44180.1
  • dtpF
 22872 - 23315 (+) globin
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  • AJI44181.1
  • dtpG
 23643 - 25058 (-) hypothetical protein
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  • AJI44182.1
  • dtpH
 25245 - 25832 (-) putative regulatory protein
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  • AJI44183.1
  • dtpI
 25921 - 26871 (+) thioredoxin reductase
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  • AJI44184.1
  • dtpJ
 26997 - 28592 (-) drug resistance transporter EmrB/QacA
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  • AJI44185.1
  • dtpK
 28756 - 29517 (+) hypothetical protein
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  • AJI44186.1
  • dtpL
 29514 - 31991 (+) hypothetical protein
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  • AJI44187.1
 32665 - 34125 (+) hypothetical protein
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  • AJI44188.1
  • dtpN
 34160 - 34984 (+) hypothetical protein
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  • AJI44189.1
 35017 - 36606 (+) hypothetical protein
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  • AJI44190.1
  • dtpP
 36576 - 40556 (-) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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