BGC0001196: desotamide biosynthetic gene cluster from Streptomyces scopuliridis
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Location: 1 - 45,196 nt. (total: 45,196 nt).
This entry is originally from NCBI GenBank KP769807.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001196
Short description desotamide biosynthetic gene cluster from Streptomyces scopuliridis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: KP769807.1
Compounds
  • desotamide
Species Streptomyces scopuliridis [taxonomy]
References
Chemical products information
desotamide
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C35H52N8O7
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AJW76700.1
1 - 1425 (+) hypothetical protein
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  • AJW76701.1
1483 - 1965 (+) transcriptional regulator
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  • AJW76702.1
1979 - 2680 (+) hydrolase
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  • AJW76703.1
2774 - 3691 (-) DsaA
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  • AJW76704.1
4368 - 5180 (-) DsaB
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  • AJW76705.1
5249 - 5752 (-) DsaC
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  • AJW76706.1
5749 - 6882 (-) DsaD
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  • AJW76707.1
6995 - 7369 (-) DsaE
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  • AJW76708.1
7474 - 7683 (-) DsaF
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  • AJW76709.1
7768 - 15696 (-) DsaG
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  • AJW76710.1
15838 - 22605 (-) DsaH
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  • AJW76711.1
23190 - 30323 (-) DsaI
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  • AJW76712.1
30474 - 31883 (-) DsaJ
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  • AJW76713.1
32053 - 34812 (-) DsaK
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  • AJW76714.1
34818 - 35498 (-) DsaL
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  • AJW76715.1
35916 - 37127 (+) DsaM
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  • AJW76716.1
37124 - 37783 (+) DsaN
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  • AJW76717.1
37956 - 38405 (-) DsaO
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  • AJW76718.1
38845 - 39531 (+) DsaP
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  • AJW76719.1
40541 - 41680 (+) DsaQ
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  • AJW76720.1
41677 - 43233 (+) ATP-binding protein
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  • AJW76721.1
43223 - 45196 (+) inner-membrane translocator
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
AJW76709.1
Module ?
Specificity: tryptophan
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
AJW76710.1
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: valine / allo-isoleucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
AJW76711.1
Module ?
Specificity: asparagine / aspartic acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (MIBiG Annotathon)
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Cleaned up synonym list
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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