BGC0001204: versipelostatin biosynthetic gene cluster from Streptomyces versipellis
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Location: 6,818 - 115,042 nt. (total: 108,225 nt).
This entry is originally from NCBI GenBank LC006086.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001204
Short description versipelostatin biosynthetic gene cluster from Streptomyces versipellis
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • PKS (Unknown)
Loci
LC006086.1
6818 - 115042
via
Compounds
  • versipelostatin
Species Streptomyces versipellis [taxonomy]
References
Chemical products information
versipelostatin Evidence:
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C61H94O17
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAQ21932.1
  • vstD
 6818 - 8035 (+) putative cytochrome P450 hydroxylase
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    • BAQ21933.1
    • vstE
    		 8032 - 8295 (+) putative ferredoxin
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      • BAQ21934.1
      • vstB1
      		 8328 - 9194 (+) putative TDP-sugar reductase
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        • BAQ21935.1
        • vstB2
        		 9225 - 9812 (-) putative TDP-sugar 3,5-epimerase
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          • BAQ21936.1
          • vstF
          		 9822 - 10871 (-) putative 3-oxoacyl-(acyl carrier protein) synthase III
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            • BAQ21937.1
            • vstG
            		 11063 - 11503 (+) hypothetical protein
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              • BAQ21938.1
              • vstH
              		 11601 - 12860 (-) putative glycosyltransferase
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                • BAQ21939.1
                • vstA1
                		 13214 - 39895 (+) putative type I polyketide synthase
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                  • BAQ21940.1
                  • vstA2
                  		 39897 - 62486 (+) putative Type I polyketide synthase
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                    • BAQ21941.1
                    • vstI
                    		 62745 - 63956 (-) putative Glycosyl transferase
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                      • BAQ21942.1
                      • vstB3
                      		 64052 - 65047 (-) putative TDP-sugar 2,3-reductase
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                        • BAQ21943.1
                        • vstB4
                        		 65203 - 65952 (-) putative NDP-sugar 4-ketoreductase
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                          • BAQ21944.1
                          • vstB5
                          		 65989 - 67539 (-) putative TDP-sugar 2,3-dehydratase
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                            • BAQ21945.1
                            • vstJ
                            		 67719 - 68147 (+) [4+2]-cycloaddition catalyzing enzyme
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                              • BAQ21946.1
                              • vstA3
                              		 68296 - 79065 (+) putative type I polyketide synthase
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                                • BAQ21947.1
                                • vstA4
                                		 79103 - 89956 (+) putative type I polyketide synthase
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                                  • BAQ21948.1
                                  • vstA5
                                  		 89963 - 94678 (+) putative type I polyketide synthase
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                                    • BAQ21949.1
                                    • vstK
                                    		 94671 - 96215 (+) putative FAD-dependent oxidoreductase
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                                      • BAQ21950.1
                                      • vstB6
                                      		 96291 - 97427 (-) putative sugar O-methyltransferase
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                                        • BAQ21951.1
                                        • vstC5
                                        		 97497 - 98528 (-) putative 3-oxoacyl-ACP synthase III
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                                          • BAQ21952.1
                                          • vstC4
                                          		 98587 - 99675 (-) putative dehydratase
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                                            • BAQ21953.1
                                            • vstC3
                                            		 99672 - 100502 (-) putative acyltransferase
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                                              • BAQ21954.1
                                              • vstC2
                                              		 100499 - 100726 (-) putative acyl carrier protein
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                                                • BAQ21955.1
                                                • vstC1
                                                		 100723 - 102615 (-) putative FKbH-like protein
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                                                  • BAQ21956.1
                                                  • vstL
                                                  		 102617 - 103993 (-) putative crotonyl-CoA reductase
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                                                    • BAQ21957.1
                                                    • vstR1
                                                    		 104019 - 104801 (-) putative SARP family regulator
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                                                      • BAQ21958.1
                                                      • vstM
                                                      		 104779 - 105507 (-) putative type II thioesterase
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                                                        • BAQ21959.1
                                                        • vstN
                                                        		 105609 - 105863 (-) hypothetical protein
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                                                          • BAQ21960.1
                                                          • vstR2
                                                          		 106182 - 108872 (-) putative transcriptional regulator
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                                                            • BAQ21961.1
                                                            • vstO
                                                            		 109114 - 109608 (-) hypothetical protein
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                                                              • BAQ21962.1
                                                              • vstP
                                                              		 109697 - 111466 (-) putative dehydrogenase
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                                                                • BAQ21963.1
                                                                • vstQ
                                                                		 112188 - 112448 (+) hypothetical protein
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                                                                  • BAQ21964.1
                                                                  • vstB7
                                                                  		 112470 - 113537 (+) putative glucose-1-phosphate thymidylyltransferase
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                                                                    • BAQ21965.1
                                                                    • vstB8
                                                                    		 113534 - 114520 (+) putative TDP-sugar 4,6-dehydratase
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                                                                      • BAQ21966.1
                                                                      • vstR3
                                                                      		 114557 - 115042 (+) putative regulator
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                                                                        Biosynthesis information
                                                                        Annotation changelog

                                                                        Entry version: 4

                                                                        Date
                                                                        Changes
                                                                        Submitters
                                                                        Reviewers
                                                                        2022-10-07
                                                                        Update chemical activity to schema version 2.11
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                        Entry version: 3

                                                                        Date
                                                                        Changes
                                                                        Submitters
                                                                        Reviewers
                                                                        2022-09-15
                                                                        Updated bioactivity data
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                        Entry version: 2

                                                                        Date
                                                                        Changes
                                                                        Submitters
                                                                        Reviewers
                                                                        2019-10-16
                                                                        Migrated from v1.4
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        2019-10-16
                                                                        Updated compound(s) information (NPAtlas curation)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                        Entry version: 1

                                                                        Date
                                                                        Changes
                                                                        Submitters
                                                                        Reviewers
                                                                        2015-08-17
                                                                        Submitted
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        Detailed domain annotation
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