BGC0001216: splenocin C biosynthetic gene cluster from Streptomyces sp. CNQ431
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Location: 6,356 - 31,635 nt. (total: 25,280 nt).
This entry is originally from NCBI GenBank KP719128.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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TTA codons
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General
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0001216
Short description splenocin C biosynthetic gene cluster from Streptomyces sp. CNQ431
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: KP719128.1
Compounds
  • splenocin C
Species Streptomyces sp. CNQ431 [taxonomy]
References
Chemical products information
splenocin C
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C29H34N2O9
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AKA54624.1
  • spnA
 6356 - 6877 (-) putative RNA polymerase sigma factor
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  • AKA54625.1
  • spnB
 6935 - 8236 (-) acyltransferase
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  • AKA54626.1
  • spnC
 8880 - 17573 (+) NRPS
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  • AKA54627.1
  • spnD
 17566 - 21387 (+) PKS
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  • AKA54628.1
  • spnE
 21443 - 22663 (+) crotonyl-CoA reductive carboxylase
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  • AKA54629.1
 22767 - 23108 (-) transposase
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  • AKA54630.1
  • spnF
 23278 - 24564 (-) AMP dependent CoA-ligase
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  • AKA54631.1
  • spnG
 24756 - 25004 (-) ACP
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  • AKA54632.1
  • spnH
 25305 - 26360 (+) phenylacetate-CoA oxygenase PaaA
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  • AKA54633.1
  • spnI
 26465 - 26659 (+) phenylacetate-CoA oxygenase PaaB
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  • AKA54634.1
  • spnJ
 26652 - 27440 (+) phenylacetate-CoA oxygenase PaaC
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  • AKA54635.1
  • spnK
 27533 - 27955 (+) phenylacetate-CoA oxygenase PaaD
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  • AKA54636.1
  • spnL
 27967 - 29070 (+) phenylacetate-CoA oxygenase PaaE
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  • AKA54637.1
  • spnM
 29105 - 29881 (+) 3-oxoacyl-ACP reductase
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  • AKA54638.1
  • spnN
 29928 - 30776 (+) tryptophan 2,3-dioxygenase
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  • AKA54639.1
  • spnO
 30958 - 31635 (+) esterase
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Annotation changelog
MIBiG version Submitter Notes
1.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: SJG3CBEHSM6A3I74YXLH6GLA, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Add compound details
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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