BGC0001221: marinophenazine A biosynthetic gene cluster from Streptomyces sp. CNQ-509
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 24,521 nt. (total: 24,521 nt).
This entry is originally from NCBI GenBank KJ451627.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001221
Short description marinophenazine A biosynthetic gene cluster from Streptomyces sp. CNQ-509
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Remarks "Cluster information for Marinophenazine A and B"
Biosynthetic class(es)
  • other (phenazine)
Loci
KJ451627.1
via Enzymatic assays
Compounds
  • marinophenazine A
  • phenaziterpene A
Species Streptomyces sp. CNQ-509 [taxonomy]
References
Chemical products information
marinophenazine A Evidence: NMR
Copy SMILES
C22H24N2O3
phenaziterpene A Evidence:
Copy SMILES
C22H24N2O2
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AIT42110.1
  • cnq720
15 - 947 (+) putative transcriptional regulator
    copy AA seq
    copy Nt seq
    • AIT42111.1
    • cnq721
    944 - 1657 (+) putative N-acylglucosamine-6-phosphate 2-epimerase
      copy AA seq
      copy Nt seq
      • AIT42112.1
      • cnq722
      1711 - 2208 (-) hypothetical protein
        copy AA seq
        copy Nt seq
        • AIT42113.1
        • cnq723
        2321 - 2842 (-) putative pyridoxamine 5'-phosphate oxidase
          copy AA seq
          copy Nt seq
          • AIT42114.1
          • cnq724
          2954 - 3889 (+) putative sigma factor
            copy AA seq
            copy Nt seq
            • AIT42115.1
            • cnq725
            3978 - 4985 (+) putative methyltransferase
              copy AA seq
              copy Nt seq
              • AIT42116.1
              • cnq726
              5112 - 5750 (-) putative FMN-dependent oxidase
                copy AA seq
                copy Nt seq
                • AIT42117.1
                • cnq727
                5793 - 6632 (-) putative trans-2,3-dihydro-3-hydroxyanthranilate isomerase
                  copy AA seq
                  copy Nt seq
                  • AIT42118.1
                  • cnq728
                  6710 - 8725 (-) putative 2-amino-2-desoxy-isochorismate synthase
                    copy AA seq
                    copy Nt seq
                    • AIT42119.1
                    • cnq729
                    8722 - 9345 (-) putative 2,3-dihydro-3-hydroxy-anthranilate (DHHA) synthase
                      copy AA seq
                      copy Nt seq
                      • AIT42120.1
                      • cnq730
                      9438 - 10631 (-) putative 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthase
                        copy AA seq
                        copy Nt seq
                        • AIT42121.1
                        • cnq731
                        10664 - 11125 (-) putative enzyme of phenazine biosynthesis
                          copy AA seq
                          copy Nt seq
                          • AIT42122.1
                          • cnq732
                          11908 - 12804 (+) putative streptogrisin A
                            copy AA seq
                            copy Nt seq
                            • AIT42123.1
                            • cnq733
                            12914 - 13267 (-) hypothetical protein
                              copy AA seq
                              copy Nt seq
                              • AIT42135.1
                              • cnq734
                              13385 - 13891 (-) putative enzyme of phenazine biosynthesis
                                copy AA seq
                                copy Nt seq
                                • AIT42124.1
                                • cnq735
                                14182 - 15408 (-) putative monooxygenase
                                  copy AA seq
                                  copy Nt seq
                                  • AIT42125.1
                                  • cnq737
                                  15408 - 15539 (-) hypothetical protein
                                    copy AA seq
                                    copy Nt seq
                                    • AIT42126.1
                                    • cnq738
                                    15577 - 16479 (-) putative prenyltransferase
                                      copy AA seq
                                      copy Nt seq
                                      • AIT42127.1
                                      • cnq739
                                      16861 - 17637 (-) hypothetical protein
                                        copy AA seq
                                        copy Nt seq
                                        • AIT42128.1
                                        • cnq740
                                        17706 - 18902 (-) hypothetical protein
                                          copy AA seq
                                          copy Nt seq
                                          • AIT42129.1
                                          • cnq741
                                          19084 - 19353 (-) hypothetical protein
                                            copy AA seq
                                            copy Nt seq
                                            • AIT42130.1
                                            • cnq742
                                            19739 - 20260 (-) putative GntR family transcriptional regulator
                                              copy AA seq
                                              copy Nt seq
                                              • AIT42131.1
                                              • cnq743
                                              20392 - 21069 (-) putative cellulose-binding protein
                                                copy AA seq
                                                copy Nt seq
                                                • AIT42132.1
                                                • cnq744
                                                21234 - 21812 (+) putative deaminase reductase
                                                  copy AA seq
                                                  copy Nt seq
                                                  • AIT42133.1
                                                  • cnq745
                                                  21837 - 23384 (-) putative MFS transporter
                                                    copy AA seq
                                                    copy Nt seq
                                                    • AIT42134.1
                                                    • cnq746
                                                    23474 - 24508 (-) putative phosphatase
                                                      copy AA seq
                                                      copy Nt seq
                                                      Biosynthesis information
                                                      Annotation changelog

                                                      Entry version: 4

                                                      Date
                                                      Changes
                                                      Submitters
                                                      Reviewers
                                                      Update chemical activity to schema version 2.11
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                      Entry version: 3

                                                      Date
                                                      Changes
                                                      Submitters
                                                      Reviewers
                                                      Fixed gene accessions
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      Updated bioactivity data
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                      Entry version: 2

                                                      Date
                                                      Changes
                                                      Submitters
                                                      Reviewers
                                                      Migrated from v1.4
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      Updated compound(s) information (NPAtlas curation)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                      Entry version: 1

                                                      Date
                                                      Changes
                                                      Submitters
                                                      Reviewers
                                                      Submitted
                                                      • (ID: 6BNBMTTKZLI3ZE3JTCJWEZIV)
                                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                      Similar known gene clusters from MIBiG 4.0
                                                      Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                      Click on reference genes to show details of similarities to genes within the current region.
                                                      Click on an accession to open that entry in the MiBIG database.