Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0001221.1:
Cluster 1Other124521

BGC0001221, marinophenazines biosynthetic gene cluster from Streptomyces sp. CNQ-509. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: marinophenazine A
SMILES string: Copy to clipboard
Molecular formula: C22N2O3H24
Exact molecular mass: 364.44 Da (Other)
Molecular activity: Cytotoxic

Class-specific details

Biosynthetic class(es):
Other
Other biosynthetic class:
Phenazine

Gene cluster description

marinophenazines (BGC0001221). Gene Cluster 1. Biosynthetic class = Other. GenBank KJ451627, positions 5112-13891. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Sequence-based prediction
MIxS-compliance:Unknown
Comments:Cluster information for Marinophenazine A and B
Contact for this cluster:Alexander Kristian Apel (Eberhard Karls Universitaet Tuebingen)

Literature references

1. Zeyhle P et al. (2014) A membrane-bound prenyltransferase catalyzes the O-prenylation of 1,6-dihydroxyphenazine in the marine bacterium Streptomyces sp. CNQ-509. Chembiochem 15(16):2385-92. doi: 10.1002/cbic.201402394. Epub 2014
2. Ruckert C et al. (2015) Complete genome sequence of Streptomyces sp. CNQ-509, a prolific producer of meroterpenoid chemistry. J Biotechnol 216:140-1. doi: 10.1016/j.jbiotec.2015.08.009. Epub