BGC0001229: SBI-06990 A1 biosynthetic gene cluster from Streptomyces bingchenggensis BCW-1
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Location: 8,356,685 - 8,365,315 nt. (total: 8,631 nt).
This entry is originally from NCBI GenBank CP002047.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
RiPP
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001229
Short description SBI-06990 A1 biosynthetic gene cluster from Streptomyces bingchenggensis BCW-1
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Remarks "The protease encoded in the two component lanthipeptide cluster is fused with a second lanthionine synthetase, LanM in the same orf SBI_06987"
Biosynthetic class(es)
  • RiPP (Lanthipeptide)
Loci NCBI GenBank: CP002047.1
Compounds
  • SBI-06990 A1
  • SBI-06989 A2
Species Streptomyces bingchenggensis BCW-1 [taxonomy]
References
Chemical products information
SBI-06990 A1 [synonyms: bingicin alpha]
(no structure information available)
SBI-06989 A2 [synonyms: bingicin beta]
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SBI_06987
  • ADI10107.1
 8356685 - 8361721 (-) type II lanthionine synthetase and transporter
  • Tailoring (Unknown)
Sequence-based prediction
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  • SBI_06988
  • ADI10108.1
 8361723 - 8364764 (-) type II lanthionine synthetase
  • Tailoring (Unknown)
Sequence-based prediction
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  • SBI_06989
  • ADI10109.1
 8364893 - 8365087 (-) lanthipeptide beta
  • Precursor biosynthesis
Sequence-based prediction
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  • SBI_06990
  • ADI10110.1
 8365112 - 8365315 (-) lanthipeptide alpha
  • Precursor biosynthesis
Sequence-based prediction
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RiPP-specific information
Subclass Lanthipeptide
Cyclic? yes
Peptidases
    SBI_06987
Precursor genes
SBI_06990
Leader sequence: MHQEFEGDISLVEELAEQDLHDAAQHGG
Core sequences:
  • TISPIDTVKIIFRVSSHFGGNGGFGLFCTLSKECQPNCN
Crosslinks:
  • 16x18 (Thioether)
  • 29x34 (Thioether)
  • 31x38 (Thioether)
Cleavage recognition sites:
  • GG
SBI_06989
Leader sequence: MQKDTDILGAWDEAELVELSEADVHGG
Core sequences:
  • TDPAVTGLILGIVAIQAGVAVGVSAAFCPTTKCTSRC
Crosslinks:
  • 24x28 (Thioether)
  • 30x33 (Thioether)
  • 34x37 (Thioether)
Cleavage recognition sites:
  • GG
Annotation changelog
MIBiG version Submitter Notes
1.2
  • Hidden contributor (ID: MMICHVHAHR3QYQ42VLNY35LY, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: 3UOU7PODQJXIM6BEPUHHRRA5, no GDPR consent given).
  • Remove negative molecular mass
Similar known gene clusters
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