BGC0001240 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001240 (Metarhizium robertsii)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	28,516	serinocyclin A/serinocyclin B	NRPS:Type I	100%

BGC0001240 - Region 1 - NRPS

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Location: 1 - 28,516 nt. (total: 28,516 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 28,517
Label		BGC0001240

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001240	1.00	NRP	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0001261	0.33	NRP	AM-toxin	Alternaria alternata
BGC0001135	0.31	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0002518	0.31	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57
BGC0001128	0.29	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0002286	0.29	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001166	0.28	NRP	HC-toxin	Alternaria jesenskae
BGC0001844	0.27	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0002437	0.27	NRP	thermoactinoamide A	Thermoactinomyces sp. AS95
BGC0000357	0.26	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001240	1.00	NRP	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0001261	0.66	NRP	AM-toxin	Alternaria alternata
BGC0001135	0.64	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0002518	0.64	NRP	syringafactin A, syringafactin C	Pseudomonas sp. SZ57
BGC0001128	0.62	NRP	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0002286	0.62	NRP	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001166	0.62	NRP	HC-toxin	Alternaria jesenskae
BGC0001844	0.61	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0002437	0.60	NRP	thermoactinoamide A	Thermoactinomyces sp. AS95
BGC0000357	0.60	NRP	cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val)	Penicillium rubens Wisconsin 54-1255

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 28516:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - Ser - D-X - bAla - D-Ser - Ser)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

X797_010654

Search NORINE for peptide: strict or relaxed

AMP-binding (51..451): X

nrpys: Acc

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A